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Author : Anonim
Publisher : American Academy of Anti-Aging Med
Page : 288 pages
File Size : 41,7 Mb
Release : 2003
Category : Family & Relationships
ISBN : 0966893735
Author : Wing-Fu Lai
Publisher : Springer Nature
Page : 511 pages
File Size : 54,7 Mb
Release : 2020-10-19
Category : Medical
ISBN : 9783030544904
This book presents a multidisciplinary assessment of the state of science in the use of systemic delivery technologies to deliver anti-aging therapeutics now under development. There is a gap between basic aging research and the development of intervention technologies. This major obstacle must be overcome before biogerontological interventions can be put into clinical practice. As biogerontology comes to understand aging as a systemic degenerative process, it is clear that there is a pressing need for technologies that enable cells and tissues in a fully developed adult body to be manipulated systemically to combat aging. The authors review advances in the chemistry and engineering of systemic delivery methods and analyze the strengths and limitations of each. The book is organized into six sections. The first offers an overview of the need for systemic delivery technologies alongside the development of anti-aging therapies and describes approaches that will be required for studying the properties and efficiency of carriers for systemic delivery. Sections II, III and IV describe recent advances in a range of strategies that may enable systemic delivery to help combat aging conditions ranging from cell senescence to decline in immune function and hormonal secretion. Section V discusses practical strategies to engineer and optimize the performance of delivery technologies for applications in systemic delivery, along with their working principles. The final section discusses technical and biological barriers that must be overcome as systemic delivery technologies move from research laboratory to clinical applications aimed at tackling aging and age-associated diseases. Benefiting scholars, students and a broader audience of interested readers, the book includes helpful glossary sections in each chapter, as well as sidebars that highlight important notes, and questions for future research.
Author : Astrid Stuckelberger
Publisher : vdf Hochschulverlag AG
Page : 330 pages
File Size : 52,7 Mb
Release : 2008
Category : Aging
ISBN : 9783728131959
The 21st century technological development is revolutionizing medicine and health care, bringing new hopes to human suffering by offering cures and treatments which were unthinkable a few decades ago. This is where anti-ageing medicine finds its niche. Anti-ageing medicine aims at slowing, arresting, and reversing phenomena associated with ageing by merging biotechnological innovation and engineered solutions. Ideally, by means of the newest medical technology, the "body machinery" should be kept fit and at peak performance all life long. Early detection of age-related dysfunction should thus be "fixed" at any age with interventions such as metabolic fine tuning, enhancement, regeneration, restoration or replacement of "body parts" (i.e. organs, skin, bone or muscle). It covers a vast array of domains: from cell therapy to pharmaceutical interventions, from bio-surgery to aesthetic surgery, from human enhancement to fortified food, from smart housing and robots to toxic-free environments. Anti-ageing medicine holds promises but also significant risks and safety issues which are addressesd in this book. It presents the latest scientific evidence on what works or does not work. It also provides public policy recommendations to ensure the protection of consumers and their rights while encouraging research and development. This book is intended for academics, health professionals, business persons, consumers and policy-makers interested in the latest evidence and ethical issues about anti-ageing medicine.
Author : Alexander M Vaiserman
Publisher : Royal Society of Chemistry
Page : 570 pages
File Size : 47,6 Mb
Release : 2017-01-18
Category : Medical
ISBN : 9781782629856
Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies. This book provides an overview of current research aimed to search for life-extending medications and describes pharmacological aspects of anti-aging medicine. Readers are introduced to the fascinating historical background of geroprotection in the first chapter. In-depth information on models for investigating geroprotective drugs precedes a section covering anti-aging properties of pharmaceutical compounds, such as calorie restriction mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. Finally, strategies to translate discoveries from aging research into drugs and healthcare policy perspectives on anti-ageing medicine are provided to give a complete picture of the field. A timely and carefully edited collection of chapters by leading researchers in the field, this book will be a fascinating and useful resource for pharmacologists, gerontologists and any scientifically interested person wishing to know more about the current status of research into anti-aging remedies, challenges and opportunities.
Author : J. Robin Harris,Viktor I. Korolchuk
Publisher : Springer
Page : 499 pages
File Size : 53,9 Mb
Release : 2019-03-19
Category : Medical
ISBN : 9789811336812
This volume of the subcellular Biochemistry series will attempt to bridge the gap between the subcellular events that are related to aging as they were described in the first volume of this set of two books and the reality of aging as this is seen in clinical practice. All chapters will start from the biochemistry or cell biology, where the data is available and work up towards the understanding that we have of aging in the various areas that are related to the subject. Key focus points for this volume are nutrition, external factors and genetics on aging. There will also be chapters that will focus on various organs or tissues in which aging has been well studied, like the eyes, the muscles, the immune system and the bones. The aim of the book project and the book project that is published in concert with this volume is to bring the subcellular and clinical areas into closer contact.
Author : Andrew Steele
Publisher : Anchor
Page : 353 pages
File Size : 45,5 Mb
Release : 2021-03-23
Category : Science
ISBN : 9780385544931
“A fascinating look at how scientists are working to help doctors treat the aging process itself, helping us all to lead longer, healthier lives.” —Sanjay Gupta, MD Aging—not cancer, not heart disease—is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: there are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are, a phenomenon known as “biological immortality.” In Ageless, Andrew Steelecharts the astounding progress science has made in recent years to secure the same for humans: to help us become old without getting frail, to live longer without ill health or disease.
Author : Vincent C. Giampapa
Publisher : CRC Press
Page : 310 pages
File Size : 55,7 Mb
Release : 2022-09-01
Category : Science
ISBN : 9781000794557
This book takes a whole new perspective concerning the approach to treating aging process. Most doctors feel they have no other options but to operate on the physical processes that occur as we grow older. Now, for the first time, there is another scientific approach that impacts on the causes of aging and not just on the effects.
Author : A4M American Academy of Anti-Aging Medicine
Publisher : A4M American Academy of Anti-Aging Medicine
Page : 238 pages
File Size : 53,7 Mb
Release : 2015-03-13
Category : Medical
ISBN : 9781934715178
Proceedings of the Twenty-First World Congress on Anti-Aging Medicine & Regenerative Biomedical Technologies, sponsored by the American Academy of Anti-Aging Medicine (A4M)
Author : Alexander M Vaiserman
Publisher : Royal Society of Chemistry
Page : 592 pages
File Size : 53,6 Mb
Release : 2017-02-01
Category : Aging
ISBN : 9781782624356
Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies. This book provides an overview of current research aimed to search for life-extending medications and describes pharmacological aspects of anti-aging medicine. Readers are introduced to the fascinating historical background of geroprotection in the first chapter. In-depth information on models for investigating geroprotective drugs precedes a section covering anti-aging properties of pharmaceutical compounds, such as calorie restriction mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. Finally, strategies to translate discoveries from aging research into drugs and healthcare policy perspectives on anti-ageing medicine are provided to give a complete picture of the field. A timely and carefully edited collection of chapters by leading researchers in the field, this book will be a fascinating and useful resource for pharmacologists, gerontologists and any scientifically interested person wishing to know more about the current status of research into anti-aging remedies, challenges and opportunities.
Author : Syed Ibrahim Rizvi,Ufuk Çakatay
Publisher : Springer
Page : 386 pages
File Size : 54,6 Mb
Release : 2018-11-02
Category : Medical
ISBN : 9789811316999
This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions – including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction – that will be of interest to scientists and researchers from various disciplines in the life sciences.
Author : Dr. Marios Kyriazis
Publisher : Watkins Media Limited
Page : 244 pages
File Size : 49,5 Mb
Release : 2012-01-01
Category : Health & Fitness
ISBN : 9781780283005
An in-depth analysis of the benefits, limitations and side effects of the most commonly used anti-ageing medicines.
Author : David A. Sinclair,Matthew D. LaPlante
Publisher : Atria Books
Page : 432 pages
File Size : 45,6 Mb
Release : 2019-09-10
Category : Science
ISBN : 9781501191978
A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.” —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.
Author : Aubrey de Grey,Michael Rae
Publisher : St. Martin's Press
Page : 452 pages
File Size : 44,7 Mb
Release : 2007-09-04
Category : Science
ISBN : 9781429931830
MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.
Author : Sandeep Kumar Singh,Chih Li Lin,Shailendra Kumar Mishra
Publisher : Academic Press
Page : 411 pages
File Size : 43,9 Mb
Release : 2022-07-19
Category : Medical
ISBN : 9780323902366
Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging is a comprehensive and timely book on all aspects of anti-aging strategies. The book provides comprehensive, foundational knowledge on the mechanisms of aging and current anti-aging strategies and approaches developed. Aging research has experienced an unprecedented advance over recent years with the discovery that the rate of aging is determined, at least to some extent, mainly by our genetics and modulated by environmental factors. The hallmarks of aging describe the molecular and cellular processes that govern biological aging and their variation in individuals. Covers different aspects of anti-aging research, from foundational knowledge to future perspectives Provides understanding on the different hallmarks of aging and how they can be applied in the development of anti-aging drugs Discusses various anti-aging strategies, including telomerase reactivation, clearance of senescent cells, stem cell-based therapy, and others
Author : Ronald Klatz,Robert Goldman, M.D.
Publisher : Bantam
Page : 417 pages
File Size : 40,5 Mb
Release : 1997-07-01
Category : Health & Fitness
ISBN : 9780553577518
Why many of us will live past 100--and enjoy our extra years. In Stopping the Clock, two pioneers of anti-aging medicine show how we can start now to regain energy and vitality, halt or reverse damage to our bodies, and avoid the diseases--heart attack, arthritis, cancer, diabetes--that do most to reduce current life expectancy. In sixteen fully-documented, information-packed chapters, Klatz and Goldman detail an up-to-the-minute longevity program, including: The key anti-aging hormones: Melatonin, DHEA, and human growth hormone, how to take them and precautions to use. The sex hormones: the role of estrogen and progesterone supplementation, including natural alternatives to prescription hormones--plus new research on testosterone supplementation for men and women. The role of the "miracle minerals"--chromium, selenium and magnesium--and the latest information on the key anti-oxidant vitamins and how to take them. A thyroid support program to avoid the many dangerous effects of thyroid deficiency. A sensible approach to anti-aging exercise--plus 25 ways to defeat the aging effects of stress. The life-long diet--including the top 25 healing foods. A longevity test to determine your current estimated lifespan. Personal longevity programs--including daily supplement regiments--from 28 leaders of anti-aging medicine. Glossary of 75 anti-aging substances available at health-food stores.