Tsh Receptor And Autoimmunity

Author : Takashi Akamizu,Jae Hoon Chung,Cesidio Giuliani,Rauf Latif,Giorgio Napolitano,Susanne Neumann
Publisher : Frontiers Media SA
Page : 126 pages
File Size : 53,5 Mb
Release : 2019-04-05
Category : Electronic
ISBN : 9782889458165

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TSH Receptor and Autoimmunity by Takashi Akamizu,Jae Hoon Chung,Cesidio Giuliani,Rauf Latif,Giorgio Napolitano,Susanne Neumann Pdf

The present Research Topic aims to provide updated reviews on TSH receptor structure and function, and its relationship with thyroid autoimmunity. Indeed, original reviews deal also with the pathogenesis of Graves' disease and its complications such as thyroid-associated opthalmopathy. Another issue that is addressed in this topic is the multifaceted nature of TSH receptor autoantibodies (TRAbs) and their role in the diagnosis and prognosis of Graves’ disease, with the most recent data on the clinical applications of TRAbs assays. Furthermore, the functional role of the TSH receptor in extrathyroidal tissues is discussed.

Author : A. Pinchera
Publisher : Springer Science & Business Media
Page : 579 pages
File Size : 43,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461309451

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Thyroid Autoimmunity by A. Pinchera Pdf

In 1956, three groups independently reported evidence that some thyroid disease appearing spontaneously in humans or experimentally induced in animals are related to autoimmune processes. The interval between these landmark discoveries and the present has witnessed a remarkable and continuing growth of both knowledge and concepts concerning the mechanisms of immune regulation, the pathogenesis of autoimmune thyroid diseases, and their clinical and laboratory manifestations. More importantly knowledge of thyroid autoimmunity has, in many respects, comprised the vanguard of an ever increasing appreciation and understanding of autoimmune diseases in general. On November 24-26 1986, an International Symposium on Thyroid Autoimmunity was held in Pisa. Its purpose was to commemorate the birth of thyroid autoimmunity as a scientific discipline, to summarize current knowledge and concepts in this area, and where possible, to anticipate areas of opportunity for the future - hence the theme of the Symposium, Memories and Perspectives. To open the meeting, the Magnifico Rettore (Chancellor) of the University of Pisa granted special Awards to Dr. Deborah Doniach, Dr. Ivan Roitt, and Dr. Noel R. Rose, who published the first fundamental studies in the field of thyroid autoimmunity, and to Dr. Duncan G. Adams, whose discovery of the long-acting thyroid stimulator (LATS) opened the door to our current understanding of the pathogenesis of Graves' disease. During the meeting thirty plenary lectures were presented.

Author : A.P. Weetman
Publisher : Springer Science & Business Media
Page : 296 pages
File Size : 55,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401150446

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Endocrine Autoimmunity and Associated Conditions by A.P. Weetman Pdf

Autoimmunity is the most common cause of endocrine disorders. This volume provides an up-to-date summary of recent advances in this important field. In addition, it describes developments in our understanding of conditions such as vitiligo and pernicious anaemia which are frequently associated with autoimmune endocrinopathies. There is a detailed review of animal models of endocrine disease which have contributed greatly to current knowledge. Furthermore, the aetiology, pathogenesis and treatment of the clinical disorders are discussed in depth. The book will be of interest to anyone working in the areas of endocrinology and immunology.

Author : Paul G. Walfish,Jack R. Wall,Robert Volpé
Publisher : Academic Press
Page : 476 pages
File Size : 44,8 Mb
Release : 2013-09-11
Category : Health & Fitness
ISBN : 9781483273983

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Autoimmunity and the Thyroid by Paul G. Walfish,Jack R. Wall,Robert Volpé Pdf

Autoimmunity and the Thyroid is a collection of papers presented at an International Satellite Meeting prior to the 7th International Congress of Endocrinology, held at the Mount Sinai Hospital, University of Toronto Medical School on June 29 and 30, 1984. The book provides presentations of participants relating to selected aspects of immune regulation and its role in autoimmune thyroid diseases. Concepts on humoral and cell-mediated immunity mechanisms in the pathogenesis of autoimmune thyroid disease are reviewed; important observations with promising clinical implications in terms of immunogenetics of Graves' and Hashimoto's diseases are presented; and selection of appropriate therapy for Graves' thyrotoxicosis, and the possibility of preventive immunosuppressive and ophthalmopathy therapy are discussed. Endocrinologists, physicians, pathologists, physiologists, and medical researchers will find the book interesting.

Author : Robert Volpe'
Publisher : CRC Press
Page : 374 pages
File Size : 49,6 Mb
Release : 1990-10-05
Category : Medical
ISBN : 0849368499

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Autoimmune Diseases of the Endocrine System by Robert Volpe' Pdf

This book is a comprehensive, easy-to-read discussion of the organ-specific autoimmune endocrine diseases emphasizing new contributions and trends for research and management. It begins with a brief chapter introducing the general principles of immunology, followed by discussions covering topics such as immunogenetics and animal models and how they can be applied toward interpreting human autoimmune endocrine diseases, autoimmune thyroid diseases, insulin-dependent diabetes mellitus hypophysitis, and Addison's disease. The book also discusses future trends toward gaining an understanding of these disorders and possible therapeutic principles. It is well-illustrated and will prove to be a useful reference source for internists, endocrinologists, and postgraduate students interested in human autoimmune endocrine diseases.

Author : Robert Volpé
Publisher : Springer Science & Business Media
Page : 434 pages
File Size : 43,7 Mb
Release : 1999-06-04
Category : Medical
ISBN : 9781592597048

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Autoimmune Endocrinopathies by Robert Volpé Pdf

Dr. Robert Volpé and his distinguished contributors comprehensively review the latest thinking about the theoretical, experimental, and clinical aspects of autoimmune endocrine disorders. These world-renowned experts examine the pathogenesis and immunogenetics of these diseases, discuss the role of sex hormones in autoimmunity, and elucidate the nature of autoantigens. They also provide clinical detail on a wide variety of autoimmune endocrinopathies, including autoimmune thyroid disease, Graves' ophthalmopathy and dermopathy, human insulin-dependent diabetes mellitus, and autoimmune adrenocortical failure. Postpartum autoimmune endocrine syndromes, autoimmune hypophysitis, and the polyglandular autoimmune syndromes are also discussed in detail. Comprehensive and authoritative, Autoimmune Endocrinopathies provides today's most up-to-date understanding of the etiology and pathogenesis of autoimmune endocrine diseases.

Author : A.M. McGregor
Publisher : Springer Science & Business Media
Page : 208 pages
File Size : 51,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400941717

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Immunology of Endocrine Diseases by A.M. McGregor Pdf

Nineteen eighty-six is a most appropriate year in which to be writing about developments in the organ-specific, autoimmune endocrine diseases. It celebrates the publication 30 years ago in 1956 of the classic papers of Roitt and Doniach and their co-workers I , and of Rose and Witebsky2 and Adams 3 and Purves . These three sets of fundamental observations provided the initial building blocks upon which much of what has been established in the field in the last 30 years was built. No publication of this nature on endocrine autoimmune disease can cover every aspect of the subject. I have chosen to highlight the organs (thyroid and pancreeas) which have attracted the most attention, and the areas of work within these fields within which most research effort is currently focused. There are still some gaps; the insulin and TSH receptors are not considered, nor in any detail are the role of cytotoxic mechanisms in mediating gland destruction. Molecular biology will undoubtedly in the next few years clarify once and for all the controversy that surrounds the structure of the TSH receptor and T cell cloning, the role of cell-mediated cytotoxicity. The pathogenetic mechanisms underlying autoimmunity are increasingly well understood and the search for the aetiology has begun.

Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 48,8 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570

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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Author : Anthony P. Weetman
Publisher : Springer Science & Business Media
Page : 434 pages
File Size : 53,7 Mb
Release : 2007-12-26
Category : Medical
ISBN : 9781597455176

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Autoimmune Diseases in Endocrinology by Anthony P. Weetman Pdf

This is a comprehensive and novel text that examines key features that predispose individuals to autoimmune diseases. The first section details the basic mechanism of autoimmunity and examines immunogenetic and environmental factors in autoimmunity. The next section examines autoimmune thyroid disease. The third section takes a look at Type 1 diabetes mellitus. In the final section, authors explain other autoimmune endocrinopathies.

Author : George S. Eisenbarth
Publisher : Landes Bioscience
Page : 292 pages
File Size : 45,5 Mb
Release : 1999
Category : Medical
ISBN : UOM:39015049978862

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Endocrine and Organ Specific Autoimmunity by George S. Eisenbarth Pdf

A dozen studies report on recent research findings for clinicians and scientists working in immunology. They discuss such topics as the immunobiology of autoimmunity, autoimmune polyendocrine syndrome types I and II, insights into the molecular mechanisms of the autoimmune thyroid diseases, type I d

Author : Robert Volpé
Publisher : Marcel Dekker
Page : 496 pages
File Size : 44,7 Mb
Release : 1985
Category : Medical
ISBN : UOM:39015009553135

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Autoimmunity and Endocrine Disease by Robert Volpé Pdf

Author : W. Savino,F. Guaraldi
Publisher : Karger Medical and Scientific Publishers
Page : 180 pages
File Size : 47,5 Mb
Release : 2017-02-28
Category : Medical
ISBN : 9783318060140

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Endocrine Immunology by W. Savino,F. Guaraldi Pdf

In the last decades, several in vitro and in vivo studies have revealed the existence of a very complex network between the neuroendocrine and immune system. Important molecular mechanisms underlying these interactions, in both physiological and pathological conditions, have also been described. Indeed, hormones play a pivotal role in the development and functional regulation of the immune system – both innate and acquired responses. Immune system cells present specific hormone receptors and themselves produce some hormones, thus influencing hormone secretion. More recently, the modulation of hormone secretion has been attempted for treating associated autoimmune disorders, further supporting the strong interplay between the endocrine and immune system. Distinguished experts, who have published extensively in their fields, have contributed comprehensive chapters to this volume. The focus is on the various aspects of endocrine-neuro-immune connections, providing an updated panorama - from basics to clinical applications - of current knowledge and still debated issues.

Author : A. Pinchera
Publisher : Unknown
Page : 458 pages
File Size : 48,9 Mb
Release : 1980
Category : Autoimmune diseases
ISBN : UCAL:B3884069

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Autoimmune Aspects of Endocrine Disorders by A. Pinchera Pdf

Author : Bruce D. Weintraub
Publisher : Lippincott Williams & Wilkins
Page : 552 pages
File Size : 51,7 Mb
Release : 1995
Category : Endocrine glands
ISBN : UOM:39015032316906

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Molecular Endocrinology by Bruce D. Weintraub Pdf

Author : Yehuda Shoenfeld,Ricard Cervera,M. Eric Gershwin
Publisher : Springer Science & Business Media
Page : 593 pages
File Size : 40,7 Mb
Release : 2010-06-08
Category : Medical
ISBN : 9781603272858

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Diagnostic Criteria in Autoimmune Diseases by Yehuda Shoenfeld,Ricard Cervera,M. Eric Gershwin Pdf

According to the Autoimmune Diseases Coordinating Committee (ADCC), between 14.7 and 23.5 million people in the USA – up to eight percent of the population are affected by autoimmune disease. Autoimmune diseases are a family of more than 100 chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. In Handbook of Autoimmune Disease, the editors have gathered in a comprehensive handbook a critical review, by renowned experts, of more than 100 autoimmune diseases, divided into two main groups, namely systemic and organ-specific autoimmune diseases. A contemporary overview of these conditions with special emphasis on diagnosis is presented. Each chapter contains the essential information required by attending physicians as well as bench scientists to understand the definition of a specific autoimmune disease, the diagnostic criteria, and the treatment.