Tissue Hypoxia And Ischemia

Author : Martin Reivich
Publisher : Springer Science & Business Media
Page : 382 pages
File Size : 52,8 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9781461590354

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Tissue Hypoxia and Ischemia by Martin Reivich Pdf

This monograph contains the proceedings of a symposium entitled, "Tissue Hypoxia and Ischemia," which was held at the Annenberg Center of the University of Pennsylvania on August 13 and 14, 1976. The symposium was jointly sponsored by the following groups at the University of Pennsylvania: the Respiratory Physiology Group of the Department of Physio logy, the Cardiopulmonary Section of the Department of Medicine, the Johnson Research Foundation, the Cerebrovascular Research Center of the Department of Neurology, the Head Injury Center of the Department of Neurosurgery, the. Institute for Environ mental Medicine, and the International Society on Oxygen Transport to Tissues. Its purpose was to promote an interdisciplinary discussion of oxygen sensors in various tissues and their mechanism of action as well as to examine the deleterious effects of hypoxia and ischemia with special reference to the brain. There were four sessions, one on the biochemistry of physi ologic oxygen sensors, two on the mechanism of oxygen sensing in tissues and one on the circulatory and metabolic aspects of cerebral hypoxia and ischemia.

Author : Martin Reivich
Publisher : Springer
Page : 400 pages
File Size : 48,6 Mb
Release : 2014-01-15
Category : Electronic
ISBN : 1461590361

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Tissue Hypoxia and Ischemia by Martin Reivich Pdf

Author : Roland N. Pittman
Publisher : Biota Publishing
Page : 117 pages
File Size : 52,5 Mb
Release : 2016-08-18
Category : Medical
ISBN : 9781615047215

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Regulation of Tissue Oxygenation, Second Edition by Roland N. Pittman Pdf

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Author : Jürgen Grote,Carsten Stick
Publisher : Fischer Gustav Verlag GmbH & Company KG
Page : 300 pages
File Size : 53,9 Mb
Release : 1996
Category : Anoxemia
ISBN : UOM:39015041128391

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Tissue Reactions in Response to Hypoxia and Ischemia by Jürgen Grote,Carsten Stick Pdf

Author : Richard E. Klabunde
Publisher : Lippincott Williams & Wilkins
Page : 689 pages
File Size : 41,7 Mb
Release : 2020-12-01
Category : Medical
ISBN : 9781975150099

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Cardiovascular Physiology Concepts by Richard E. Klabunde Pdf

Praised for its concise coverage, this highly accessible monograph lays a foundation for understanding the underlying concepts of normal cardiovascular function and offers a welcome alternative to a more mechanistically oriented approach or an encyclopedic physiology text. Clear explanations, ample illustrations and engaging clinical cases and problems provide the perfect guidance for self-directed learning and prepare you to excel in clinical practice.

Author : Kusal Das,Mallanagouda Shivanagouda Biradar
Publisher : BoD – Books on Demand
Page : 146 pages
File Size : 44,7 Mb
Release : 2018-12-12
Category : Medical
ISBN : 9781789848281

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Hypoxia and Anoxia by Kusal Das,Mallanagouda Shivanagouda Biradar Pdf

The molecular deprivation of oxygen is manifested by hypoxia, a deficiency of oxygen and anoxia, or the absence of oxygen supply to the tissues. This book entitled Hypoxia and Anoxia will cover a broad range of understanding on hypoxia and anoxia from molecular mechanisms to pathophysiology. Hypoxia and anoxia stimulate multiple systems through specific cell signal transduction pathways and regulate several transcriptional factors like HIF-1, REST to encode genes for VEGF, Epo, etc. This book will also highlight different types of hypoxia and anoxia along with their impact on apoptosis, cardiovascular pathophysiology, and glucose regulatory mechanisms. This book will be a ready reckoner to give a deep understanding of the oxygen-sensing environment in vivo for researchers, academicians, and clinicians throughout the world.

Author : Can Ince,J. Kesecioglu,L. Telci,K. Akpir
Publisher : Springer
Page : 0 pages
File Size : 40,7 Mb
Release : 2011-10-01
Category : Science
ISBN : 1461380022

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Oxygen Transport to Tissue XVII by Can Ince,J. Kesecioglu,L. Telci,K. Akpir Pdf

nd The 22 meeting of the International Society on Oxygen Transport to Tissue (LS. O. T. T. ) of which this volume is the scientific proceedings, was held in Istanbul, Turkey on August 22-26, 1994. It was a historical occasion in that it was almost 200 years to the day that one of the founding fathers of oxygen research, Antoine Lavoisier, on May 8, 1794 found his early demise at the hands of the guillotine. This spirit of history set the tone of the conference and in the opening lecture the contribution that this part of the world has given to the understanding of oxygen transport to tissue was highlighted. In particular, the contribution of Galen of Pergamon (129-200) was discussed who for the first time demon strated that blood flowed through the arteries and whose view on the physiology of the circulation dominated the ancient world for well over a millennium. A forgotten chapter in the history of the circulation of the blood is the contribution made by Ibn al Nafis of Damascus (1210-1280) who for the first time described the importance of the pulmonary circulation by stating that all venous blood entering the right ventricle ofthe heart passes to the left ventricle, not through pores in the septum of the heart as had been postulated by Galen, but through the circulation of the lungs.

Author : Hans-Jürgen Machulla
Publisher : Springer Science & Business Media
Page : 208 pages
File Size : 55,8 Mb
Release : 1999-01-31
Category : Medical
ISBN : 0792355296

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Imaging of Hypoxia by Hans-Jürgen Machulla Pdf

Reports observations and findings using PET, SPECT, and other imaging technologies to identify tissue that is not getting sufficient oxygen, which can enhance the development and progress of disease and increase the resistance of tumors to radiation therapy. Nine papers from a workshop in Tubingen-Buhl, Germany in 1995 consider such aspects as the biology of technetium-based hypoxic tissue localizing compounds, molecular design approaches of hypoxia tracers, pre-clinical and clinical studies of quantifying hypoxia with radiolabeled fluoromisonidazole, and evaluating hypoxia in diabetes. Annotation copyrighted by Book News, Inc., Portland, OR

Author : Gabriel G. Haddad,Shan Ping Yu
Publisher : Springer Science & Business Media
Page : 268 pages
File Size : 55,9 Mb
Release : 2009-01-06
Category : Medical
ISBN : 9781603275798

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Brain Hypoxia and Ischemia by Gabriel G. Haddad,Shan Ping Yu Pdf

Brain Hypoxia and Ischemia explores the various aspects of cell death and survival that are crucial for understanding the basic mechanisms underlying brain hypoxia and ischemia. Chapters focus on a panorama of issues including the role of ion channels/transporters, mitochondria and apoptotic mechanisms, the roles of glutamate/NMDA, mechanisms in penumbral cells and the importance of intermittent hypoxia and gene regulation under these stressful conditions. The volume explores findings from both mammalian and invertebrate model systems and their applicability to human systems and diseases. Careful consideration is also given to differences in hypoxia and ischemia across development. This volume aims to increase the understanding of these mechanisms and to stimulate research on better diagnosis and treatment of diseases that afflict the brain and potentially other organs when O2 levels are dysregulated. Brain Hypoxia and Ischemia is designed for neuroscientists, clinicians and medical/graduate students for use in both basic research and clinical practice.

Author : Robert C. Roach,Peter D. Wagner,Peter H. Hackett
Publisher : Springer Science & Business Media
Page : 466 pages
File Size : 47,9 Mb
Release : 2002-01-31
Category : Medical
ISBN : 0306466961

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Hypoxia by Robert C. Roach,Peter D. Wagner,Peter H. Hackett Pdf

Hypoxia remains a constant threat throughout life. It is for this reason that the International Hypoxia Society strives to maintain a near quarter century tradition of presenting a stimulating blend of clinical and basic science discussions. International experts from many fields have focused on the state-of-the-art discoveries in normal and pathophysiological responses to hypoxia. Topics in this volume include gene-environment interactions, a theme developed in both a clinical context regarding exercise and hypoxia, as well as in native populations living in high altitudes. Furthermore, experts in the field have combined topics such as skeletal muscle angiogenesis and hypoxia, high altitude pulmonary edema, new insights into the biology of the erythropoietin receptor, and the latest advances in cardiorespiratory control in hypoxia. This volume explores the fields of anatomy, cardiology, biological transport, and biomedical engineering among many others.

Author : Jing Zheng,Chi Zhou
Publisher : BoD – Books on Demand
Page : 456 pages
File Size : 47,8 Mb
Release : 2017-02-01
Category : Medical
ISBN : 9789535128953

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Hypoxia and Human Diseases by Jing Zheng,Chi Zhou Pdf

This book contains a total of 21 chapters, each of which was written by experts in the corresponding field. The objective of this book is to provide a comprehensive and updated overview of cellular and molecular mechanisms underlying hypoxia's impacts on human health, as well as current advances and future directions in the detection, recognition, and management of hypoxia-related disorders. This collection of articles provides a clear update in the area of hypoxia research for biomedical researchers, medical students, nurse practitioners, and practicing clinicians in the fields of high altitude biology, cardiovascular biology and medicine, tumor oncology, obstetrics, pediatrics, and orthodontics and for others who may be interested in hypoxia.

Author : Anthony Marmarou,Ross Bullock,Cees Avezaat,Alexander Baethmann,Donald Becker,Mario Brock,Julian Hoff,Hajime Nagai,Hans-J. Reulen,Graham Teasdale
Publisher : Springer Science & Business Media
Page : 464 pages
File Size : 54,8 Mb
Release : 1998-08-24
Category : Medical
ISBN : 3211830944

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Intracranial Pressure and Neuromonitoring in Brain Injury by Anthony Marmarou,Ross Bullock,Cees Avezaat,Alexander Baethmann,Donald Becker,Mario Brock,Julian Hoff,Hajime Nagai,Hans-J. Reulen,Graham Teasdale Pdf

This volume contains the most recent works on intracranial pressure and neuromonitoring in brain injury selected from 300 abstracts submitted to the 10th International Symposium on Intracranial Pressure. It includes state of the art monitoring of the brain injured patient in intensive care as well as the current state of knowledge in neurochemical and oxygen monitoring of the injured brain. Recent advances in molecular mechanisms of injury and the pathophysiology of ischemia and trauma are also included. "... this publication presents a comprehensive survey of the present state of art in the field and thus gives directions for further research to those engaged in ICP measurement and neuromonitoring”. Intensive Care Med

Author : Robert Fitridge,M. M. Thompson
Publisher : University of Adelaide Press
Page : 589 pages
File Size : 40,9 Mb
Release : 2011
Category : Medical
ISBN : 9781922064004

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Mechanisms of Vascular Disease by Robert Fitridge,M. M. Thompson Pdf

New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Author : Hugo Lagercrantz
Publisher : Cambridge University Press
Page : 427 pages
File Size : 46,8 Mb
Release : 2010-01-07
Category : Medical
ISBN : 9780521889759

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The Newborn Brain by Hugo Lagercrantz Pdf

The new edition of this respected work presents a comprehensive review of basic mechanisms of fetal and neonatal brain development.

Author : George J. Siegel,Bernard W. Agranoff
Publisher : Lippincott Raven
Page : 1216 pages
File Size : 44,5 Mb
Release : 1999
Category : Medical
ISBN : UOM:39015045578211

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Basic Neurochemistry by George J. Siegel,Bernard W. Agranoff Pdf

Illustrations by Lorie M. Gavulic, MFA Sponsored by the American Society for Neurochemistry.