Treatise On Ocular Drug Delivery

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Treatise on Ocular Drug Delivery

Ashim K. Mitra
Treatise on Ocular Drug Delivery Book PDF

Author : Ashim K. Mitra
Publisher : Bentham Science Publishers
Page : 301 pages
File Size : 52,5 Mb
Release : 2013-06-26
Category : Medical
ISBN : 9781608051755

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Treatise on Ocular Drug Delivery by Ashim K. Mitra Pdf

A multidisciplinary approach is increasingly being adapted by the Pharmaceutical industry to tackle several challenges in developing efficacious treatment solutions. The field of Ophthalmology is no less different. Treatise on Ocular Drug Delivery is a unique collection of information put together by various experts in the field. One of the major goals behind this volume is to link clinical information with the current strategies employed in ocular drug delivery. This monograph covers a range of topics on ocular pharmacology. Chapters in the e-book cover several aspects of drug delivery research such as the biochemical background of specific eye diseases, challenges for ocular drug delivery, the role of influx and efflux transporters, novel drug delivery systems, pharmacokinetics, regulatory aspects, and patenting opportunities for researchers. This E-Book would serve as a suitable reference for pharmacy graduates, medical students, professional scientists and ophthalmic clinicians in academic and industrial laboratories.

Update on Polymers for Ocular Drug Delivery

Atish S Mundada
Update on Polymers for Ocular Drug Delivery Book PDF

Author : Atish S Mundada
Publisher : Smithers Rapra
Page : 210 pages
File Size : 45,7 Mb
Release : 2011-12-20
Category : Medical
ISBN : 9781847355645

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Update on Polymers for Ocular Drug Delivery by Atish S Mundada Pdf

The eye is the most easily accessible site for topical administration of a medication. Drugs are commonly applied to the eye for localised action on the surface or in the interior of the eye. A major problem in ocular therapeutics is the attainment of an optimal drug concentration at the site of action. Poor bioavailability of drugs from ocular dosage forms is mainly due to the precorneal loss factors which include tear dynamics, non-productive absorption, transient residence time in the cul-de-sac, and the relative impermeability of the corneal epithelial membrane. Due to these physiological and anatomical constraints only a small fraction of the drug, effectively 1% or even less of the instilled dose is ocularly absorbed. The effective dose of medication administered ophthalmically may be altered by increasing the retention time of medication in contact with the surface of the eye. To date, Pharmaceutical Technologists have tried to develop different novel formulations like gel, ocular inserts, collagen shields, implants, liposomes, nanoparticles, penetration enhancers and in-situ gelling systems, in order to increase the bioavailability and duration of the therapeutic action of ocular drugs and polymers plays an important role in all these approaches. This book provides detailed information regarding all such polymers which have been used and shown to be excellent in improving the bioavailability of ocular drugs.

Ophthalmic Drug Delivery Systems

Ashim K. Mitra
Ophthalmic Drug Delivery Systems Book PDF

Author : Ashim K. Mitra
Publisher : CRC Press
Page : 847 pages
File Size : 54,9 Mb
Release : 2019-12-02
Category : Electronic
ISBN : 0367446766

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Ophthalmic Drug Delivery Systems by Ashim K. Mitra Pdf

The second edition of this text assembles significant ophthalmic advances and encompasses breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery.

Treatise on Controlled Drug Delivery

Agis F. Kydonieus
Treatise on Controlled Drug Delivery Book PDF

Author : Agis F. Kydonieus
Publisher : Routledge
Page : 659 pages
File Size : 54,7 Mb
Release : 2017-10-02
Category : Medical
ISBN : 9781351406871

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Treatise on Controlled Drug Delivery by Agis F. Kydonieus Pdf

An introductory but detailed treatise which includes some 1,000 references and solved examples and end-of-chapter problems, making it useful to both students and practitioners. The pharmokinetics, pharmacodynamics, and biological and biopharmaceutical parameters pertinent to each route of administra

Handbook of Polymers for Pharmaceutical Technologies, Processing and Applications

Vijay Kumar Thakur,Manju Kumari Thakur
Handbook of Polymers for Pharmaceutical Technologies Processing and Applications Book PDF

Author : Vijay Kumar Thakur,Manju Kumari Thakur
Publisher : John Wiley & Sons
Page : 496 pages
File Size : 47,6 Mb
Release : 2015-07-27
Category : Technology & Engineering
ISBN : 9781119041405

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Handbook of Polymers for Pharmaceutical Technologies, Processing and Applications by Vijay Kumar Thakur,Manju Kumari Thakur Pdf

Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers

Drug Delivery for the Retina and Posterior Segment Disease

Jayvadan K. Patel,Vijaykumar Sutariya,Jagat Rakesh Kanwar,Yashwant V. Pathak
Drug Delivery for the Retina and Posterior Segment Disease Book PDF

Author : Jayvadan K. Patel,Vijaykumar Sutariya,Jagat Rakesh Kanwar,Yashwant V. Pathak
Publisher : Springer
Page : 494 pages
File Size : 49,5 Mb
Release : 2018-10-08
Category : Medical
ISBN : 9783319958071

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Drug Delivery for the Retina and Posterior Segment Disease by Jayvadan K. Patel,Vijaykumar Sutariya,Jagat Rakesh Kanwar,Yashwant V. Pathak Pdf

This book addresses the issues relating to a wide variety of ocular diseases from which millions of people suffer. Long-term challenges include visual impairment and ocular blindness. Certain ocular diseases are quite rare, whereas others, such as cataracts, age-related macular degeneration (AMD), and glaucoma, are very common, especially in the aging population. A rapid expansion of new technologies in ocular drug delivery and new drug candidates, including biologics, to treat these challenging diseases in the retina and posterior segments of the eye have recently emerged. These approaches are necessary because the eye has many unique barriers to drug delivery. Thus, this timely reference Drug Delivery for the Retina and Posterior Segment Disease compiles and analyzes recent advances in the research and development of drug delivery systems for retina and posterior segment diseases of the eye, with an emphasis on the use of implantable devices, iontophoresis as well as micro- and nanoparticles.

Ophthalmic Product Development

Seshadri Neervannan,Uday B. Kompella
Ophthalmic Product Development Book PDF

Author : Seshadri Neervannan,Uday B. Kompella
Publisher : Springer Nature
Page : 650 pages
File Size : 55,6 Mb
Release : 2022-03-11
Category : Medical
ISBN : 9783030763671

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Ophthalmic Product Development by Seshadri Neervannan,Uday B. Kompella Pdf

This is a comprehensive textbook addressing the unique aspects of drug development for ophthalmic use. Beginning with a perspective on anatomy and physiology of the eye, the book provides a critical appraisal of principles that underlie ocular drug product development. The coverage encompasses topical and intraocular formulations, small molecules and biologics (including protein and gene therapies), conventional formulations (including solutions, suspensions, and emulsions), novel formulations (including nanoparticles, microparticles, and hydrogels), devices, and specialty products. Critical elements such as pharmacokinetics, influence of formulation technologies and ingredients, as well as impact of disease conditions on products development are addressed. Products intended for both the front and the back of the eye are discussed with an eye towards future advances. @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:3 0 0 0 1 0;}@font-face {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-469750017 -1073732485 9 0 511 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-ansi-language:EN-US; mso-fareast-language:EN-US;}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:EN-US; mso-fareast-language:EN-US;}div.WordSection1 {page:WordSection1;}

Organic Materials as Smart Nanocarriers for Drug Delivery

Alexandru Mihai Grumezescu
Organic Materials as Smart Nanocarriers for Drug Delivery Book PDF

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 768 pages
File Size : 52,8 Mb
Release : 2018-03-26
Category : Science
ISBN : 9780128136645

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Organic Materials as Smart Nanocarriers for Drug Delivery by Alexandru Mihai Grumezescu Pdf

Organic Materials as Smart Nanocarriers for Drug Delivery presents the latest developments in the area of organic frameworks used in pharmaceutical nanotechnology. An up-to-date overview of organic smart nanocarriers is explored, along with the different types of nanocarriers, including polymeric micelles, cyclodextrins, hydrogels, lipid nanoparticles and nanoemlusions. Written by a diverse range of international academics, this book is a valuable reference for researchers in biomaterials, the pharmaceutical industry, and those who want to learn more about the current applications of organic smart nanocarriers. Explores the most recent molecular- and structure-based applications of organic smart nanocarriers in drug delivery Highlights different smart nanocarriers and assesses their intricate organic structural properties for improving drug delivery Assesses how molecular organic frameworks lead to more effective drug delivery systems

Introduction to Nanomaterials in Medicine

Mohammad Rabiee,Navid Rabiee,Reza Salarian,Ghazal Rabiee
Introduction to Nanomaterials in Medicine Book PDF

Author : Mohammad Rabiee,Navid Rabiee,Reza Salarian,Ghazal Rabiee
Publisher : Morgan & Claypool Publishers
Page : 111 pages
File Size : 42,8 Mb
Release : 2019-03-21
Category : Science
ISBN : 9781643274164

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Introduction to Nanomaterials in Medicine by Mohammad Rabiee,Navid Rabiee,Reza Salarian,Ghazal Rabiee Pdf

Advancement in the field of nanotechnology has revolutionized the field of medicines and pharmaceuticals in the twentieth century. The proper use of nanomaterials in medical applications requires a proper understanding of these compounds. This correct understanding, beyond the physical and chemical properties, must also have the correct logic of use. In other words, the strategic use of nanomaterials with applicable perspective can also help to advance research, but if we go forward with the current research perspective that leads to the expansion of inapplicable researches, the intrinsic importance of using these nanomaterials is eliminated. This book, considering the importance of nanomaterials and their application in medicine, as well as the significant growth of biomaterials in research fields, introduces the variables law (Rabiee's theory) for the implementation of this research and the establishment of a proper strategy. Considering that the degree of number of biomaterial and host variables follow a variety factors, and by increasing the degree of number of biomaterials and host variables, the degree of total variables also increases and as a result, performance and, consequently, biomaterial behavior in the host environment will have less control and predictive capabilities. For an external substance that is supposed to be in the human body, it must be predictable and controllable, In addition, according to the principle that the host in a fixed person does not have the ability to change, therefore, by using the simpler biomaterials (with less variables), the above goal is more accessible. It should be noted that in addition to observing biocompatibility tests for a biomaterial based on existing protocols and standards, the Applicable Compatibility (AC) parameter is also required in accordance with Rabiee's theory. This book is written in accordance with Rabiee's theory and the contents of this book should be evaluated from this perspective.

Nanotechnology Based Delivery of Phytoconstituents and Cosmeceuticals

Deep Pooja,Hitesh Kulhari
Nanotechnology Based Delivery of Phytoconstituents and Cosmeceuticals Book PDF

Author : Deep Pooja,Hitesh Kulhari
Publisher : Springer Nature
Page : 353 pages
File Size : 44,6 Mb
Release : 2024-01-10
Category : Medical
ISBN : 9789819953141

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Nanotechnology Based Delivery of Phytoconstituents and Cosmeceuticals by Deep Pooja,Hitesh Kulhari Pdf

This book explores the role of nanotechnology in the delivery of natural phytoconstituents and cosmeceuticals. It presents polymeric nanocarriers, lipid-based nanocarriers, metal/metal oxide nanocarriers, protein nanocarriers, and dendrimers for the delivery of phytoconstituents. Further, it focuses on the usage of phytocompounds in various cosmeceutical products and nano delivery technologies used in the delivery of various cosmeceuticals. Finally, the book reviews the toxicity issues of nanoparticles in the delivery of phytoconstituents and cosmeceuticals and regulatory aspects for clinical applications of nano phytomedicines. This book is helpful for academicians and researchers working in pharmaceutical sciences, nano science, material science, plant science, and cosmetic science.

Bioadhesive Drug Delivery Systems

Vincent M. Lenaerts,Robert Gurny
Bioadhesive Drug Delivery Systems Book PDF

Author : Vincent M. Lenaerts,Robert Gurny
Publisher : CRC Press
Page : 244 pages
File Size : 54,6 Mb
Release : 1989-11-30
Category : Medical
ISBN : 084935367X

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Bioadhesive Drug Delivery Systems by Vincent M. Lenaerts,Robert Gurny Pdf

This comprehensively written text covers, in-depth, all aspects of bioadhesive systems. Bioadhesive systems are presently playing a major role in the field because of their ability to maintain a dosage form at a precise body-site for a prolonged period of time over which the active principle is progressively released. Included in this book are descriptions of the different mucosae in healthy and pathological situations, a theoretical approach of polymers-mucin interactions, and a comparative description of the methods used to evaluate bioadhesion. Up-to-date reviews of pharmaceutical applications are also given - subdivided according to the route of administration and type of system. It also contains a chapter devoted to the fundamentals of bioadhesion. This reference is an indispensable guide for researchers in the pharmaceutical field as well as academic researchers.

Intraocular Drug Delivery

Glenn J. Jaffe,Paul Ashton,P. Andrew Pearson
Intraocular Drug Delivery Book PDF

Author : Glenn J. Jaffe,Paul Ashton,P. Andrew Pearson
Publisher : CRC Press
Page : 385 pages
File Size : 52,9 Mb
Release : 2006-03-13
Category : Medical
ISBN : 9781420016505

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Intraocular Drug Delivery by Glenn J. Jaffe,Paul Ashton,P. Andrew Pearson Pdf

This reference studies the most recent advances in the development of ocular drug delivery systems. Covering methods to treat or prevent ocular inflammation, retinal vascular disease, retinal degeneration, and proliferative eye disease, this source covers breakthroughs in the management of endophthalmitis, uveitis, diabetic macular edema, and age-r

Natural Polymers

Ololade Olatunji
Natural Polymers Book PDF

Author : Ololade Olatunji
Publisher : Springer
Page : 372 pages
File Size : 53,5 Mb
Release : 2015-12-24
Category : Technology & Engineering
ISBN : 9783319264141

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Natural Polymers by Ololade Olatunji Pdf

This book introduces the most recent innovations in natural polymer applications in the food, construction, electronics, biomedical, pharmaceutical, and engineering industries. The authors provide perspectives from their respective range of industries covering classification, extraction, modification, and application of natural polymers from various sources in nature. They discuss the techniques used in analysis of natural polymers in various systems incorporating natural polymers as well as their intrinsic properties.

Novel Formulations and Future Trends

Amit Kumar Nayak,Kalyan Kumar Sen
Novel Formulations and Future Trends Book PDF

Author : Amit Kumar Nayak,Kalyan Kumar Sen
Publisher : Elsevier
Page : 695 pages
File Size : 41,9 Mb
Release : 2024-03-25
Category : Medical
ISBN : 9780323972451

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Novel Formulations and Future Trends by Amit Kumar Nayak,Kalyan Kumar Sen Pdf

Novel Formulations and Future Trends, Volume Three in the Recent and Future Trends in Pharmaceutics series, explores aspects of pharmaceutics with an original approach focused on technology, novelties and future trends. It discusses the most important developments in drug delivery, including important and exciting areas such as mucosal, implantable, transdermal, gastroretentive, vaccine and targeted drug delivery systems. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. This is an essential reference for researchers in academia and industry as well as advanced graduate students. New technologies are also explored including 3D printing and computational pharmaceutics. Explores the most recent technologies in drug delivery in detail Contains contributions from the leading experts from academia, research, industry and regulatory agencies Includes high quality illustrations, flow charts and tables for easy understanding of concepts Discusses practical examples and research case studies

Natural Polysaccharides in Drug Delivery and Biomedical Applications

Md Saquib Hasnain,Amit Kumar Nayak
Natural Polysaccharides in Drug Delivery and Biomedical Applications Book PDF

Author : Md Saquib Hasnain,Amit Kumar Nayak
Publisher : Academic Press
Page : 654 pages
File Size : 54,8 Mb
Release : 2019-07-23
Category : Business & Economics
ISBN : 9780128170564

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Natural Polysaccharides in Drug Delivery and Biomedical Applications by Md Saquib Hasnain,Amit Kumar Nayak Pdf

Natural Polysaccharides in Drug Delivery and Biomedical Applications provides a fundamental overview of natural polysaccharides, their sources, extraction methodologies, and characterizations. It covers specific natural polysaccharides and their effective application in drug delivery and biomedical use. Additionally, chapters in the book discuss key topics including the sources and extraction methodologies of natural polysaccharides, their role in tissue engineering applications, polysaccharide-based nanoparticles in biomedical applications, and their role in the delivery of anticancer drugs. Written by industry leaders and edited by experts, this book emphasizes recent advances made in the field. Natural Polysaccharides in Drug Delivery and Biomedical Applications provides academics, researchers, and pharmaceutical health care professionals with a comprehensive book on polysaccharides in pharmaceutical delivery process. Provides fundamental concepts of natural polysaccharides as it applies to the pharmaceutical, biomedical, and biotechnology industries Includes contributions from global leaders and experts from academia, industry, and regulatory agencies in the application of natural polysaccharides in pharmaceutical products and biomedical utilization Offers practical examples, illustrations, chemical structures, and research case studies to help explain natural polysaccharides concepts in drug delivery and biomedical applications