Tweaking The Telomeres

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Tweaking The Telomeres

Author : Fergus Dignan
Publisher : ShieldCrest Publishing
Page : 128 pages
File Size : 48,9 Mb
Release : 2020-02-18
Category : Humor
ISBN : 9781912505753

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Tweaking The Telomeres by Fergus Dignan Pdf

The story describes two biotechnology companies, one ethical, the other not: Peter Melville, a scientist at GeneGACT, has good reason to hope for a cure for Huntington s disease. Hank Wubbernacker, the CEO at Suckett Ansee, is attempting to create human immortality. When Peter finds out, he plans to sabotage the research project by breaking into Suckett Ansee's laboratories. Peter also has domestic dramas: his wife, Jane, has been sexually molested by a work colleague but there is no redress due to a lack of evidence. However, the molester has reckoned without Peter s cat, Psycho! Does Jane get her revenge? Does Peter save the planet from human immortality? Read on . . .

Tweaking The Telomeres

Author : Fergus Dignan
Publisher : ShieldCrest Publishing
Page : 240 pages
File Size : 45,9 Mb
Release : 2020-02-12
Category : Humor
ISBN : 9781911090991

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Tweaking The Telomeres by Fergus Dignan Pdf

The story describes two biotechnology companies, one ethical, the other not: Peter Melville, a scientist at GeneGACT, has good reason to hope for a cure for Huntington’s disease. Hank Wubbernacker, the CEO at Suckett Ansee, is attempting to create human immortality. When Peter finds out, he plans to sabotage the research project by breaking into Suckett Ansee’s laboratories. Peter also has domestic dramas: his wife, Jane, has been sexually molested by a work colleague but there is no redress due to a lack of evidence. However, the molester has reckoned without Peter’s cat, Psycho! Does Jane get her revenge? Does Peter save the planet from human immortality? Read on . . .

The Telomere Effect

Author : Dr. Elizabeth Blackburn,Dr. Elissa Epel
Publisher : Grand Central Publishing
Page : 328 pages
File Size : 44,5 Mb
Release : 2017-01-03
Category : Health & Fitness
ISBN : 9781455587964

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The Telomere Effect by Dr. Elizabeth Blackburn,Dr. Elissa Epel Pdf

The New York Times bestselling book coauthored by the Nobel Prize winner who discovered telomerase and telomeres' role in the aging process and the health psychologist who has done original research into how specific lifestyle and psychological habits can protect telomeres, slowing disease and improving life. Have you wondered why some sixty-year-olds look and feel like forty-year-olds and why some forty-year-olds look and feel like sixty-year-olds? While many factors contribute to aging and illness, Dr. Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection. They and other scientists have found that changes we can make to our daily habits can protect our telomeres and increase our health spans (the number of years we remain healthy, active, and disease-free). The Telemere Effect reveals how Blackburn and Epel's findings, together with research from colleagues around the world, cumulatively show that sleep quality, exercise, aspects of diet, and even certain chemicals profoundly affect our telomeres, and that chronic stress, negative thoughts, strained relationships, and even the wrong neighborhoods can eat away at them. Drawing from this scientific body of knowledge, they share lists of foods and suggest amounts and types of exercise that are healthy for our telomeres, mind tricks you can use to protect yourself from stress, and information about how to protect your children against developing shorter telomeres, from pregnancy through adolescence. And they describe how we can improve our health spans at the community level, with neighborhoods characterized by trust, green spaces, and safe streets. The Telemere Effect will make you reassess how you live your life on a day-to-day basis. It is the first book to explain how we age at a cellular level and how we can make simple changes to keep our chromosomes and cells healthy, allowing us to stay disease-free longer and live more vital and meaningful lives.

Telomeres and Telomerase

Author : Derek J. Chadwick,Gail Cardew
Publisher : John Wiley & Sons
Page : 250 pages
File Size : 46,9 Mb
Release : 2008-04-30
Category : Science
ISBN : 9780470515440

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Telomeres and Telomerase by Derek J. Chadwick,Gail Cardew Pdf

Telomeres and Telomerase Chairman: Sydney Brenner, 1997 Telomeres are the protective genetic elements located at the ends of chromosomes and are essential for correct chromosomal structure and function. They are not fully replicated by the conventional DNA polymerase system because DNA synthesis occurs only in the 5' to 3' direction and requires an RNA primer for initiation. Consequently, cells require a special enzyme to maintain the telomeric ends of chromosomes during each round of replication. This enzyme, telomerase, is a ribonucleoprotein that extends chromosome ends by adding short stretches of nucleotide repeats using a portion of its integral RNA component as the template. Recently, much excitement has been generated by the suggestion that telomerase, or rather the absence of telomerase and the resultant loss of terminal DNA, is a cause of human ageing. The evidence for this is twofold: the telomeres of certain cells in culture shorten during their lifespan; and immortalization of cells is associated, at least in some cases, with the maintenance of telomeres and telomerase activity. The latter observation prompted the analysis of clinical samples from patients with cancer and the demonstration that, in contrast to normal somatic cells, malignant cells possess telomerase activity. This is a unique book. Not only does it contain the latest experimental results from an international group of experts, but it also includes critical examinations of the current evidence, and discussions that attempt to identify the central and underlying concepts of this rapidly expanding field.

Leslie Beck's Longevity Diet

Author : Leslie Beck
Publisher : Penguin Canada
Page : 384 pages
File Size : 47,7 Mb
Release : 2011-01-04
Category : Health & Fitness
ISBN : 9780143184485

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Leslie Beck's Longevity Diet by Leslie Beck Pdf

Celebrity nutritionist Leslie Beck unlocks the secrets to achieving good health and maintaining an active and energetic lifestyle in Leslie Beck's Longevity Diet. Complete with food plans, new recipes, tips, and strategies, Leslie Beck's Longevity Diet includes the following information to help slow aging and promote lifelong vitality: • The secrets of the healthiest cultures from around the world • A quick and easy self-assessment to determine how your lifestyle habits are affecting your health • The top foods to slow aging and promote health • How to determine your own caloric prescription for optimal longevity

Elizabeth Blackburn and the Story of Telomeres

Author : Catherine Brady
Publisher : MIT Press
Page : 413 pages
File Size : 51,5 Mb
Release : 2009-02-13
Category : Biography & Autobiography
ISBN : 9780262512459

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Elizabeth Blackburn and the Story of Telomeres by Catherine Brady Pdf

The story of molecular biologist Elizabeth Blackburn and her groundbreaking research on telomeres and what it reveals about the resourceful opportunism that characterizes the best scientific thinking. Molecular biologist Elizabeth Blackburn—one of Time magazine's 100 “Most Influential People in the World” in 2007—made headlines in 2004 when she was dismissed from the President's Council on Bioethics after objecting to the council's call for a moratorium on stem cell research and protesting the suppression of relevant scientific evidence in its final report. But it is Blackburn's groundbreaking work on telomeric DNA, which launched the field of telomere research, that will have the more profound and long-lasting effect on science and society. In this compelling biography, Catherine Brady tells the story of Elizabeth Blackburn's life and work and the emergence of a new field of scientific research on the specialized ends of chromosomes and the enzyme, telomerase, that extends them. In the early stages of telomere research, telomerase, heralded as a potential cure for cancer and diseases related to aging, attracted the voracious interest of biotech companies. The surrounding hype succeeded in confusing the role of telemorase in extending the life of a cell with a mechanism that might extend the lifespan of an entire organism. In Brady's hands, Blackburn's story reveals much about the tension between pure and applied science, the politicking that makes research science such a competitive field, and the resourceful opportunism that characterizes the best scientific thinking. Brady describes the science accessibly and compellingly. She explores Blackburn's struggle to break down barriers in an elite, male-dominated profession, her role as a mentor to other women scientists (many of whom have made their mark in telomere research), and the collaborative nature of scientific work. This book gives us a vivid portrait of an exceptional woman and a new understanding of the combination of curiosity, imaginative speculation, and aesthetic delight that powers scientific discovery.

Neuroscience Calisthenics: Hijack your Body Clock

Author : Jean Fallacara
Publisher : Jean Fallacara
Page : 230 pages
File Size : 44,6 Mb
Release : 2024-07-03
Category : Medical
ISBN : 8210379456XXX

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Neuroscience Calisthenics: Hijack your Body Clock by Jean Fallacara Pdf

We all aspire to live a long and healthy life and know that staying active is critical to achieving this goal. Usually, we think that we physically peak at around the age of 20. That is what most physical trainers, athletes but mainly the media are going to tell you and they are not wrong. It is just what they are used to seeing. Most gymnasts or Olympic athletes that we see usually reach their prime in their late teens or early twenties. Taking Usain Bolt as an example; he had been earning gold medals in several world championships ever since he was 15 but it was in the 2008 Beijing Olympics that he lit up the world stage when he broke the world record for the 100-meter sprint. Since then he has progressed on to break his own record and earn consecutive gold medals in the 2012 and 2016 Olympics, up until he was 30, after which he retired.

Ageless

Author : Andrew Steele
Publisher : Anchor
Page : 353 pages
File Size : 48,5 Mb
Release : 2021-03-23
Category : Science
ISBN : 9780385544931

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Ageless by Andrew Steele Pdf

“A fascinating look at how scientists are working to help doctors treat the aging process itself, helping us all to lead longer, healthier lives.” —Sanjay Gupta, MD Aging—not cancer, not heart disease—is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: there are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are, a phenomenon known as “biological immortality.” In Ageless, Andrew Steelecharts the astounding progress science has made in recent years to secure the same for humans: to help us become old without getting frail, to live longer without ill health or disease.

The 6 Keys

Author : Jillian Michaels
Publisher : Little, Brown Spark
Page : 241 pages
File Size : 40,5 Mb
Release : 2018-12-18
Category : Health & Fitness
ISBN : 9780316448611

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The 6 Keys by Jillian Michaels Pdf

Reverse the effects of aging and maintain optimal health for life through the revolutionary 6 Keys program by New York Times bestselling author Jillian Michaels. With Master Your Metabolism, Jillian Michaels showed us how to take control of the metabolic machinery underneath our weight and health struggles. Now she's ahead of the curve again -- conquering the mayhem, myths, and misunderstandings associated with aging. After all, if you can decide your weight, why not your age? Scientists and doctors have identified six major age inciters: metabolism, damaged macromolecules, epigenetics, inflammation, stress adaptation, telomeres. The 6 Keys presents an ageless health, fitness, and beauty plan that addresses all six of them -- and gets them working for you instead of against you. Empowering and rigorously researched, The 6 Keys outlines powerful lifestyle interventions, dietary guidelines, exercise plans, and vanguard strategies for cultivating mindfulness that restore and protect human performance, keeping you fit, healthy, and beautiful for life.

Exercise Is Medicine

Author : Judy Foreman
Publisher : Oxford University Press, USA
Page : 385 pages
File Size : 46,8 Mb
Release : 2020-01-02
Category : Medical
ISBN : 9780190685461

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Exercise Is Medicine by Judy Foreman Pdf

Aging, despite its dismal reputation, is actually one of the great mysteries of the universe. Why don't we just reproduce, then exit fast, like salmon? Could aging just be one big evolutionary accident? Is senescence, the gradual falling apart of our bodies, at least partially avoidable? Can we extend the healthy lifespan and reduce the lingering, debilitating effects of senescence? In this book, investigative health journalist Judy Foreman suggests that we actually can, and the key element is exercise, through its myriad effects on dozens of molecules in the brain, the muscles, and other organs. It's no secret, of course, that exercise is good for you and that exercise can extend longevity. What Foreman uncovers through extensive research into evolutionary biology, exercise physiology, and the new field of geroscience is exactly why exercise is so powerful - the mechanisms now being discovered that account for the vast and varied effects of exercise all over the body. Though Foreman also delves into pills designed to combat aging and so-called exercise "mimetics," or pills that purport to produce the effects of exercise without the sweat, her resounding conclusion is that exercise itself is by far the most effective, and safest, strategy for promoting a long, healthy life. In addition to providing a fascinating look at the science of exercise's effects on the body, Foreman also provides answers to the most commonly asked practical questions about exercise.

Up

Author : Hilary Tindle
Publisher : Penguin
Page : 268 pages
File Size : 49,9 Mb
Release : 2013-05-30
Category : Health & Fitness
ISBN : 9781101623633

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Up by Hilary Tindle Pdf

Why looking up matters A positive attitude is important, but until now we didn’t know how important. In Up, a practicing physician and NIH-funded researcher draws on her research and experience to show that our outlook on life— our unique patterns of thinking and feeling about ourselves, others, and the world—may be the key to how well and how fast we age. From wrinkles to cognitive decline, our outlook affects our health at every level. Using the framework of outlook GPS, Up illustrates how we can gauge our current attitude latitude and move to healthier ground. Tindle brings a fresh eye to attitudinal traits such as optimism, noting that it has many faces, including the face of her own struggling optimism. Using the 7 Steps of Attitudinal Change that she applies to her own patients, Tindle offers us a path toward healthy aging. Prescriptive and accessible, Up puts forward a paradigm shift in how we age and treat disease, giving even the most struggling optimists a chance for hope. It will appeal to readers of The Longevity Project by Howard S. Friedman and Leslie R. Martin as well as The Blue Zones by Dan Buettner.

Betrayed by Nature

Author : Robin Hesketh
Publisher : St. Martin's Press
Page : 272 pages
File Size : 48,8 Mb
Release : 2012-05-08
Category : Science
ISBN : 9780230341920

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Betrayed by Nature by Robin Hesketh Pdf

Seven million people die from cancer each year around the world, and many more are impacted by this universal scourge. In Betrayed by Nature, research scientist and lecturer Robin Hesketh demystifies the nature of cancer. Hesketh provides a concise and comprehensive history of both the science and the medical advances made over the decades. He takes the reader on a riveting tour of human biology; he explains how cancers start, what is meant by ‘a mutation', and how mutations can make cells grow abnormally and spread around our bodies. Drawing on the latest discoveries from the Human Genome Project, Hesketh reveals the strides being made in understanding this malevolent disease and makes accessible the science of today's treatments. Betrayed by Nature looks forward to the day when many cancers can be treated readily and effectively. With cancer afflicting one in three people worldwide, this is an illuminating and optimistic look at the past, present, and future of cancer.

Becoming Immortal

Author : Stanley Shostak
Publisher : State University of New York Press
Page : 322 pages
File Size : 41,6 Mb
Release : 2012-02-01
Category : Science
ISBN : 9780791488416

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Becoming Immortal by Stanley Shostak Pdf

Providing the philosophical, practical, and theoretical leverage for abandoning evolution and development in favor of engineering human beings, Becoming Immortal examines the directions biological change might take if civilization were to take charge of its own destiny. With the aid of embryonic manipulation, cloning, and stem-cell therapy, immortality would seem within the reach of future generations. The question is, "Do we presently have the wisdom to undertake creating immortal organisms?" The author examines every facet of this question, from theory to practice, and provides an answer through an in-depth analysis of life and death.

Younger

Author : Sara Gottfried
Publisher : HarperCollins
Page : 249 pages
File Size : 42,7 Mb
Release : 2017-03-07
Category : Health & Fitness
ISBN : 9780062316295

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Younger by Sara Gottfried Pdf

NEW YORK TIMES BESTSELLER The New York Times bestselling author of The Hormone Cure and The Hormone Reset Diet shows every woman how to create a lifestyle that will help her look great, feel energized, and slow down the effects of aging. Feel destined for cellulite, saddle bags, and belly fat? Does your family come from a long line of Alzheimer's, cancer, or heart disease? Will nothing help your aging skin or declining libido or flagging energy? This book is for you. The body is magnificent but it doesn't come with a lifetime warranty, or an operating manual. You're the result of millions of years of evolution, but many of the adaptations that helped your ancestors survive are now working overtime to accelerate the aging process. The assumption here is that we are our genes and therefore trapped by the past. The good news is that your genetic code—the DNA sequence that is the biochemical basis of heredity—can play a minor role in the way you age. The scientific reality is that 90 percent of the signs of aging and disease are caused by lifestyle choices, not your genes. In other words, you have the capability to overcome and transform your genetic history and tendencies. Harvard/MIT—trained physician Sara Gottfried, M.D. has created a revolutionary 7-week program that empowers us to make the critical choices necessary to not just look young, but also feel young. Dr. Gottfried identifies and builds this book around the five-key factors that lead to accelerated aging -the muscle factor, the brain factor, the hormone factor, the gut factor, and the toxic fat factor. The 7-week program addresses these factors and treats them in an accessible and highly practical protocol and is as follows: Feed—Week 1 Sleep—Week 2 Move—Week 3 Release—Week 4 Expose—Week 5 Soothe—Week 6 Think—Week 7 Younger increases not only your lifespan, but also your healthspan. Dr. Gottfried's program makes it possible to change the way you age, stay younger longer, and remain healthy and vibrant for all of your days.

Telomere Miracle

Author : Ed Park, MD
Publisher : Hay House, Inc
Page : 280 pages
File Size : 55,5 Mb
Release : 2018-01-23
Category : Health & Fitness
ISBN : 9781401952587

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Telomere Miracle by Ed Park, MD Pdf

What if everything you think you know about getting older and staying healthy is wrong? Ed Park, M.D., offers the revolutionary idea that disease and aging in humans all arises from a single source: genetic errors caused by shortening of telomeres, or the sequences of DNA at the ends of our chromosomes. Telomeres naturally wear down over time, and thus when cells replicate (as they do all the time in our bodies), they’re creating progressively poorer-quality duplicates of themselves, like making a Xerox of a Xerox of a Xerox. Ultimately, the body deteriorates, resulting in a range of ailments, many of which we associate with aging—from diabetes to hypertension to macular degeneration to cancer. Happily, Ed tells us, it’s possible to slow or even reverse this process and effectively turn back the clock. In The Telomere Miracle, he explains cutting-edge science in a lively style, using illustrations and metaphors ranging from auto parts to superheroes. Then he shows readers how they can intervene in the aging process by boosting the activity of the enzyme telomerase naturally by understanding and optimizing six key areas of breathing, mindset, sleep, exercise, diet, and supplements.