Uhplc In Life Sciences

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UHPLC in Life Sciences

Author : Davy Guillarme,Jean-Luc Veuthey
Publisher : Royal Society of Chemistry
Page : 484 pages
File Size : 52,6 Mb
Release : 2015-11-09
Category : Science
ISBN : 9781782626152

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UHPLC in Life Sciences by Davy Guillarme,Jean-Luc Veuthey Pdf

Since its commercial introduction in 2004, UHPLC (Ultra-High Performance Liquid Chromatography) has begun to replace conventional HPLC in academia and industry and interest in this technique continues to grow. Both the increases in speed and resolution make this an attractive method; particularly to the life sciences and more than 1500 papers have been written on this strongly-evolving topic to date. This book provides a solid background on how to work with UHPLC and its application to the life sciences. The first part of the book covers the basics of this approach and the specifics of a UHPLC system, providing the reader with a solid background to working properly with such a system. The second part examines the application of UHPLC to the life sciences, with a focus on drug analysis strategies. UHPLC-MS, a key technique in pharmaceutical and toxicological analyses, is also examined in detail. The editors (Davy Guillarme and Jean-Luc Veuthey) were some of the earliest adopters of UHPLC and have published and lectured extensively on this topic. Between them they have brought together an excellent team of contributors from Europe and the United States, presenting a wealth of expertise and knowledge. This book is an essential handbook for anyone wishing to adopt an UHPLC system in either an academic or industrial setting and will benefit postgraduate students and experienced workers alike.

HPLC and UHPLC for Practicing Scientists

Author : Michael W. Dong
Publisher : John Wiley & Sons
Page : 410 pages
File Size : 40,6 Mb
Release : 2019-07-23
Category : Science
ISBN : 9781119313762

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HPLC and UHPLC for Practicing Scientists by Michael W. Dong Pdf

A concise yet comprehensive reference guide on HPLC/UHPLC that focuses on its fundamentals, latest developments, and best practices in the pharmaceutical and biotechnology industries Written for practitioners by an expert practitioner, this new edition of HPLC and UHPLC for Practicing Scientists adds numerous updates to its coverage of high-performance liquid chromatography, including comprehensive information on UHPLC (ultra-high-pressure liquid chromatography) and the continuing migration of HPLC to UHPLC, the modern standard platform. In addition to introducing readers to HPLC’s fundamentals, applications, and developments, the book describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. HPLC and UHPLC for Practicing Scientists, Second Edition offers three new chapters. One is a standalone chapter on UHPLC, covering concepts, benefits, practices, and potential issues. Another examines liquid chromatography/mass spectrometry (LC/MS). The third reviews at the analysis of recombinant biologics, particularly monoclonal antibodies (mAbs), used as therapeutics. While all chapters are revised in the new edition, five chapters are essentially rewritten (HPLC columns, instrumentation, pharmaceutical analysis, method development, and regulatory aspects). The book also includes problem and answer sections at the end of each chapter. Overviews fundamentals of HPLC to UHPLC, including theories, columns, and instruments with an abundance of tables, figures, and key references Features brand new chapters on UHPLC, LC/MS, and analysis of recombinant biologics Presents updated information on the best practices in method development, validation, operation, troubleshooting, and maintaining regulatory compliance for both HPLC and UHPLC Contains major revisions to all chapters of the first edition and substantial rewrites of chapters on HPLC columns, instrumentation, pharmaceutical analysis, method development, and regulatory aspects Includes end-of-chapter quizzes as assessment and learning aids Offers a reference guide to graduate students and practicing scientists in pharmaceutical, biotechnology, and other industries Filled with intuitive explanations, case studies, and clear figures, HPLC and UHPLC for Practicing Scientists, Second Edition is an essential resource for practitioners of all levels who need to understand and utilize this versatile analytical technology. It will be a great benefit to every busy laboratory analyst and researcher.

Mass Spectrometry in Life Sciences and Clinical Laboratory

Author : Goran Mitulović
Publisher : BoD – Books on Demand
Page : 156 pages
File Size : 40,6 Mb
Release : 2021-06-02
Category : Science
ISBN : 9781838818616

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Mass Spectrometry in Life Sciences and Clinical Laboratory by Goran Mitulović Pdf

Mass spectrometry is a state-of-the-art tool for basic biological research and applied clinical diagnostics. This book covers sample preparation for mass spectrometric analysis for proteomics, clinical studies, and food analysis. In addition, it explores possible directions for further developing the technology and its potential applications.

Advances in Chromatography

Author : Nelu Grinberg,Peter W. Carr
Publisher : CRC Press
Page : 307 pages
File Size : 47,7 Mb
Release : 2017-12-12
Category : Medical
ISBN : 9781351655491

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Advances in Chromatography by Nelu Grinberg,Peter W. Carr Pdf

For more than five decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. For Volume 55, established, well-known chemists offer cutting-edge reviews of chromatographic methods to pay tribute to the late Eli Grushka, beloved series editor, who inspired and mentored many in the field of separation science. The clear presentation of topics and vivid illustrations for which this series has become known makes the material accessible and engaging to analytical, biochemical, organic, polymer, and pharmaceutical chemists at all levels of technical skill.

The HPLC Expert II

Author : Stavros Kromidas
Publisher : John Wiley & Sons
Page : 380 pages
File Size : 43,5 Mb
Release : 2017-04-10
Category : Science
ISBN : 9783527339723

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The HPLC Expert II by Stavros Kromidas Pdf

How can I use my HPLC/UHPLC equipment in an optimal way, where are the limitations of the technique? These questions are discussed in detail in the sequel of the successful "HPLC Expert" in twelve chapters written by experts in the respective fields. The topics encompass - complementary to the first volume - typical HPLC users' problems and questions such as gradient optimization and hyphenated techniques (LC-MS). An important key aspect of the book is UHPLC: For which analytical problem is it essential, what should be considered? Besides presentation of latest developments directly from the main manufacturers, also UHPLC users and independent service engineers impart their knowledge. Consistent with the target groups, the level is advanced, but the emphasis is on practical applications.

Principles and Practice of Modern Chromatographic Methods

Author : Kevin Robards,Danielle Ryan
Publisher : Academic Press
Page : 532 pages
File Size : 49,6 Mb
Release : 2021-12-03
Category : Science
ISBN : 9780128220979

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Principles and Practice of Modern Chromatographic Methods by Kevin Robards,Danielle Ryan Pdf

Principles and Practice of Modern Chromatographic Methods, Second Edition takes a comprehensive, unified approach in its presentation of chromatographic techniques. Like the first edition, the book provides a scientifically rigid, but easy-to-follow presentation of chromatography concepts that begins with the purpose and intent of chromatographic theory - the “what and why that are left out of other books attempting to cover these principles. This fully revised second edition brings the content up-to-date, covering recent developments in several new sections and an additional chapter on composite methods. New topics include sample profiling, sample preparation, sustainable green chemistry, 2D chromatography, miniaturization/nano-LC, HILIC, and more. Contains thorough chapters that begin with an updated schematic overview and a visual representation of the content Avoids the obfuscation of different terminologies and classification systems that are prevalent in the area, such as the relationship between liquid chromatography and column chromatography Provides integrated and comprehensive topic coverage based on chromatographic bibliometrics and survey reports on the relative usage of chromatographic techniques

Natural Product Extraction

Author : Juliana Prado,Mauricio Rostagno
Publisher : Royal Society of Chemistry
Page : 757 pages
File Size : 54,6 Mb
Release : 2022-07-20
Category : Science
ISBN : 9781839165900

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Natural Product Extraction by Juliana Prado,Mauricio Rostagno Pdf

Natural products are used by the food, pharmaceutical and cosmetics industries, and extraction technologies and potential applications for plant extracts are of interest to many industrial sectors. Extraction of natural products in an economic and environmentally friendly way is of high importance to all industries involved. The second edition of this book presents an updated, holistic, in-depth view of the more environmentally benign techniques available for the extraction of natural products, along with their newest applications and case studies. Conventional and emerging extraction techniques are discussed in detail. New topics include enzymes, pulsed electric energy, and on-line/in-line analysis. Written for academics and industrialists working in both natural product extraction and green chemistry, this new edition provides a valuable update on current trends in the field.

Gradient HPLC for Practitioners

Author : Stavros Kromidas
Publisher : John Wiley & Sons
Page : 269 pages
File Size : 54,7 Mb
Release : 2019-04-16
Category : Science
ISBN : 9783527812769

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Gradient HPLC for Practitioners by Stavros Kromidas Pdf

This practical guide for analytical scientists explains the use of gradients in liquid chromatography. The fundamentals of gradient separations, as well as the most common application scenarios are addressed, from LC-MS coupling to biochromatography to the separation of ionic substances. Throughout, this handy volume provides detailed hands-on information for practitioners, enabling them to use gradient separation methods reliably and efficiently.

State-of-the-Art Technologies in Food Science

Author : Murlidhar Meghwal,Megh R. Goyal
Publisher : CRC Press
Page : 397 pages
File Size : 55,7 Mb
Release : 2018-08-14
Category : Science
ISBN : 9781351676625

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State-of-the-Art Technologies in Food Science by Murlidhar Meghwal,Megh R. Goyal Pdf

There has been a growing interest in the health benefits derived from fruits and vegetables and the food products based on them. Many foods contain various phytochemicals, flavonoids, fibers, macronutrients and micronutrients, minerals, etc. that are good for health and essential for keeping good health. This volume provides a global perspective of the current state of food and health research, innovation, and emerging trends. It focuses on topics of food for better health, including functional foods and nutraceutical foods. The book is divided into several sections, covering: • Foods for Human Health Promotion and Prevention of Diseases, which include fruits, vegetables, and grains: their peels and fiber for better human health, health prospects of bioactive peptides derived from seed storage proteins, mushrooms as a novel source of antihyperlipidemic agents, and emerging foodborne illnesses and their prevention. • Specific Fruits, Spices and Dairy-Based Functional Foods for Human Health, which looks at the functional medicinal values of fenugreek, fruits as functional foods, and functional fermented dairy products. • Issues, Challenges, and Specialty Topics in Food Science, which focuses mainly on the stability issues of whole wheat flour, physicochemical properties and quality of food lipids, methods for food analysis and quality control, and interventions of ohmic heating technology in foods. The volume will be of interest to health practitioners, food specialists, nutrition producers and suppliers, practicing food process engineers, food technologists, researchers, food industry professionals, and faculty and upper-level students in food science.

Issues in Biomedical Engineering Research and Application: 2011 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 1453 pages
File Size : 41,9 Mb
Release : 2012-01-09
Category : Technology & Engineering
ISBN : 9781464964541

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Issues in Biomedical Engineering Research and Application: 2011 Edition by Anonim Pdf

Issues in Biomedical Engineering Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biomedical Engineering Research and Application. The editors have built Issues in Biomedical Engineering Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biomedical Engineering Research and Application in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biomedical Engineering Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Liquid Chromatography

Author : Salvatore Fanali,Bezhan Chankvetadze,Paul R. Haddad,Colin Poole,Marja-Liisa Riekkola
Publisher : Elsevier
Page : 886 pages
File Size : 51,6 Mb
Release : 2023-04-20
Category : Science
ISBN : 9780323999991

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Liquid Chromatography by Salvatore Fanali,Bezhan Chankvetadze,Paul R. Haddad,Colin Poole,Marja-Liisa Riekkola Pdf

Liquid Chromatography: Fundamentals and Instrumentation, Third Edition offers a single source of authoritative information on all aspects of the practice of modern liquid chromatography. The book gives those working in academia and industry the opportunity to learn, refresh, and deepen their understanding of the field by covering basic and advanced theoretical concepts, recognition mechanisms, conventional and advanced instrumentation, method development, data analysis, and more. This third edition addresses new developments in the field with updated chapters from expert researchers. The book is a valuable reference for research scientists, teachers, university students, industry professionals in research and development, and quality control managers. Emphasizes the integration of chromatographic methods and sample preparation Provides important data related to complex matrices, sample preparation, and data handling Gives background information to facilitate the choice of LC sub-technique and experimental conditions, mobile and stationary phases, detectors, data processing, and more Offers comprehensive updates to all chapters Includes new chapters on chiral recognition, co-solvents and mobile phase additives, physicochemical measurements, and identification and quantitation in mass spectrometry

Advances in Nanotechnology Research and Application: 2011 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 8760 pages
File Size : 52,6 Mb
Release : 2012-01-09
Category : Technology & Engineering
ISBN : 9781464920585

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Advances in Nanotechnology Research and Application: 2011 Edition by Anonim Pdf

Advances in Nanotechnology Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Nanotechnology. The editors have built Advances in Nanotechnology Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nanotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Nanotechnology Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Handbook of Chemical and Biological Plant Analytical Methods, 3 Volume Set

Author : Shilin Chen,Andrew Marston,Hermann Stuppner
Publisher : John Wiley & Sons
Page : 1176 pages
File Size : 48,9 Mb
Release : 2014-07-15
Category : Medical
ISBN : 9781118874981

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Handbook of Chemical and Biological Plant Analytical Methods, 3 Volume Set by Shilin Chen,Andrew Marston,Hermann Stuppner Pdf

Plants and plant-derived compounds and drugs are becoming moreand more popular with increasing numbers of scientists researchingplant analysis. The quality control of herbal drugs is alsobecoming essential to avoid severe health problems, and in thefuture many more new drugs will be developed from plantsources. This three-volume Handbook, featuring 47 detailed review articles,is unique as it deals with chemical and biological methodologiesfor plant analysis. It presents the most important and mostaccurate methods which are available for plant analysis. This comprehensive work is divided into six sections asfollows: Sample preparation and identification – discussingplant selection and collection, followed by extraction and samplepreparation methodologies. Extraction and sample preparation methodologies Instrumentation for chemical analysis - severalinstrumentations for chemical plant analysis are presented with anemphasis on hyphenated techniques, e.g. the coupling between HPLCand mass spectroscometry, and HPLC with NMR. Strategies for selective classes of compounds –coverage of the most interesting classes of compounds such aspolysaccharides, saponins, cardiotonic glycosides, alkaloids,terpenoids, lipids, volatile compounds and polyphenols (flavonoids, xanthones, coumarins, naphthoquinones, anthraquinones,proanthocyanidins, etc.). Biological Analysis - includes phenotyping, DNA barcodingtechniques, transcriptome analysis , microarray, metabolomics andproteomics. Drugs from Plants – covers the screening of plantextracts and strategies for the quick discovery of novelbioactive natural products. Safety assessment of herbal drugs ishighly dependent on outstanding chromatographic and spectroscopicmethods which are also featured here. This Handbook introduces to scientists involved in plant studiesthe current knowledge of methodologies in various fields ofchemically- and biochemically-related topics in plantresearch. The content from this Handbook will publish online within theEncyclopedia of Analytical Chemistry via Wiley Online Library: ahref="http://www.wileyonlinelibrary.com/ref/eac"http://www.wileyonlinelibrary.com/ref/eac/a Benefit from the introductory offer, valid until 30 November2014! Introductory price: £425.00 / $695.00 /€550.00 List price thereafter: £495.00 / $795.00 / €640.00

Novel Developments in Pharmaceutical and Biomedical Analysis

Author : Atta-ur- Rahman,Sibel A. Ozkan,Rida Ahmed
Publisher : Bentham Science Publishers
Page : 466 pages
File Size : 49,8 Mb
Release : 2018-04-24
Category : Science
ISBN : 9781681085746

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Novel Developments in Pharmaceutical and Biomedical Analysis by Atta-ur- Rahman,Sibel A. Ozkan,Rida Ahmed Pdf

Recent Advances in Analytical Techniques is a series of updates in techniques used in chemical analysis. Each volume presents information about a selection of analytical techniques. Readers will find information about developments in analytical methods such as chromatography, electrochemistry, optical sensor arrays for pharmaceutical and biomedical analysis. Novel Developments in Pharmaceutical and Biomedical Analysis is the second volume of the series and covers the following topics: o Chromatographic assays of solid dosage forms and their drug dissolution studies o UHPLC method for the estimation of bioactive compounds o HILIC based LC/MS for metabolite analysis o In vitro methods for the evaluation of oxidative stress o Application of vibrational spectroscopy in studies of structural polymorphism of drugs o Electrochemical sensors based on conductive polymers and carbon nanotubes o Optical sensor arrays for pharmaceutical and biomedical analyses o Chemical applications of ionic liquids o New trends in enantioanalysis of pharmaceutical compounds

Nitro Compounds—Advances in Research and Application: 2012 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 150 pages
File Size : 45,5 Mb
Release : 2012-12-26
Category : Science
ISBN : 9781481604260

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Nitro Compounds—Advances in Research and Application: 2012 Edition by Anonim Pdf

Nitro Compounds—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Nitro Compounds. The editors have built Nitro Compounds—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nitro Compounds in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Nitro Compounds—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.