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Author : A. G. Dalton,Françoise Haguenau
Publisher : Unknown
Page : 240 pages
File Size : 47,8 Mb
Release : 1967
Category : Kidneys
ISBN : OCLC:500447439
Author : Albert J. Dalton,Françoise Haguenau
Publisher : Academic Press
Page : 253 pages
File Size : 47,9 Mb
Release : 2013-09-17
Category : Science
ISBN : 9781483266473
Ultrastructure in Biological Systems, Volume 2: Ultrastructure of the Kidney provides an overview of the state of knowledge on the ultrastructure of the mammalian kidney. The application of the electron microscope to studies of the kidney resulted in the demonstration of the hitherto undetected early thickening of the basement membrane of glomerular capillaries in glomerulonephritis. Yet many problems remain, particularly in relation to the correlation between function and the ultrastructure of components of the kidney—mesangium, glomerulus, juxtaglomerular apparatus, and the renal tubules. It is only recently that the mesangium has come to be accepted as real, and many questions remain as to the function of its cells. The existence of true membranes between foot processes of the epithelial cells of glomeruli is a newly established fact; but what this has to do with glomerular filtration is not known at present. Granules apparently secretory in nature have been identified in cells of the juxtaglomerular apparatus, but so far their presence has not been correlated with specific functional change. Artifacts introduced at fixation are now known to have considerable relevance in interpreting the ultrastructure of the normal nephron. These are paraphrased views of the contributors to this monograph who, while acquainting the reader with the research being carried on in these areas, have also brought into focus the many problems still awaiting solution.
Author : Arvid Bernhard Maunsbach,T. Steen Olsen,Erik Christensen
Publisher : Unknown
Page : 485 pages
File Size : 53,5 Mb
Release : 1980-01-01
Category : Kidneys
ISBN : 0124812503
Author : Rubén P. Laguens,Víctor Raúl Miatello
Publisher : Unknown
Page : 384 pages
File Size : 43,5 Mb
Release : 1964
Category : Anatomy, Pathological
ISBN : UOM:39015052210096
Author : H. Bergman
Publisher : Springer Science & Business Media
Page : 783 pages
File Size : 51,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461259077
This volume, focusing on the ureter and the diseases which involve it, is an updated second edition. Many journals and textbooks deal with the physiology, pathology, diagnosis, and therapy of derangements of the urinary tract. In most instances, however, the discussion properly centers on the disease process itself and its primary aspects, with only a tan gential description of effects on the ureter. The editor is therefore correct that the ureter itself should be considered a major organ. Though it has been regarded in the recent past as a simple muscular tube, reacting to stretching or filling by contraction, this simplistic view of ureteral phys iology is changing fast. With expanded knowledge of ureteral physiology, a pharmacology is developing which is becoming useful to the clinician in many ways. One of the most interesting aspects of the ureter is its role in inducing the permanent kidney, the metanephros. Relatively slight displacements in the origin of the ureteral bud result in ectopic ureteral orifices and a wide range of congenital anomalies. An ureteral bud which arises medial to the normal position at the genu of the mesonephric duct results in a lateral, and usually incompetent, ureterovesical junction after the duct is taken up to form a portion ofthe trigone. This appears certainly to be the developmental mechanism which results in primary reflux.
Author : Charles Rouiller,Alex Fritz Muller
Publisher : Unknown
Page : 0 pages
File Size : 46,5 Mb
Release : 1969
Category : Diseases
ISBN : 0125988028
Author : Margit Pavelka,Jürgen Roth
Publisher : Springer Science & Business Media
Page : 366 pages
File Size : 49,6 Mb
Release : 2010-07-16
Category : Science
ISBN : 9783211993903
The period between 1950 and 1980 were the golden unique insights into how pathological processes affect years of transmission electron microscopy and produced cell organization. a plethora of new information on the structure of cells This information is vital to current work in which that was coupled to and followed by biochemical and the emphasis is on integrating approaches from functional studies. TEM was king and each micrograph proteomics, molecular biology, genetics, genomics, of a new object produced new information that led to molecular imaging and physiology and pathology to novel insights on cell and tissue organization and their understand cell functions and derangements in disease. functions. The quality of data represented by the images In this current era, there is a growing tendency to of cell and tissues had been perfected to a very high level substitut e modern light microscopic techniques for by the great microscopists of that era including Palade, electron microscopy, because it is less technically Porter, Fawcett, Sjostrand, Rhodin and many others. At demanding and is more readily available to researchers- present, the images that we see in leading journals for This atlas reminds us that the information obtained by the most part do not reach the same technical level and electron microscopy is invaluable and has no substitute.
Author : Anonim
Publisher : Unknown
Page : 516 pages
File Size : 45,7 Mb
Release : 1979
Category : Kidneys
ISBN : CUB:U183048569909
Author : Thomas C. Jones,Gordon C. Hard,Ulrich Mohr
Publisher : Springer Science & Business Media
Page : 496 pages
File Size : 55,9 Mb
Release : 2013-03-12
Category : Medical
ISBN : 9783642803352
A complete update on the safety testing of foods, drugs, and chemicals in laboratory animals, featuring: - a thorough review of each subject area with extensive revision in line with new information and concepts - electron micrographs in exquisite detail to illustrate results of recent research - the effects of many carcinogens described succinctly and illustrated in detail - neoplasms described in detail and compared with natural and induced tumours in other species - standardised nomenclature. Of interest to those interested in the many applications to human patients, Urinary System: - facilitates uniform interpretation of bioassay results world-wide - provides a basis for understanding mechanisms involved in the functions and malfunctions of the most minute, but important structures of the kidneys - explains the functional significance of details by identifying the composition of structures at the molecular level. Forming a solid basis for understanding the causes and effects of disease of the urinary system, this is essential reading for pathologists, toxicologists, regulatory agencies, and all those involved in carcinogenicity and toxicity studies.
Author : Anonim
Publisher : Unknown
Page : 856 pages
File Size : 40,6 Mb
Release : 1976
Category : American periodicals
ISBN : UOM:39015007296919
Author : Fred Hossler
Publisher : John Wiley & Sons
Page : 966 pages
File Size : 49,9 Mb
Release : 2014-06-03
Category : Science
ISBN : 9781118284537
Ultrastructure Atlas of Human Tissues presents a variety of scanning and transmission electron microscope images of the major systems of the human body. Photography with the electron microscope records views of the intricate substructures and microdesigns of objects and tissues, and reveals details within them inaccessible to the naked eye or light microscope. Many of these views have significance in understanding normal structure and function, as well as disease processes. This book offers a unique and comprehensive look at the structure and function of tissues at the subcellular and molecular level, an important perspective in understanding and combating diseases. • Presents the major systems of the human body through scanning and transmission electron microscope images • Has images prepared almost exclusively from human tissues • Includes electron micrographs of common pathologies such as fibrotic and emphysemic lung, kidney stones, sickle cell anemia, and skin parasites • Contains sets of 3D images in most chapters
Author : Xin J. Zhou,Zoltan G. Laszik,Tibor Nadasdy,Vivette D. D'Agati
Publisher : Cambridge University Press
Page : 691 pages
File Size : 45,9 Mb
Release : 2017-03-02
Category : Medical
ISBN : 9781316613986
An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.
Author : Kathy Pritchard-Jones,Jeffrey S. Dome
Publisher : Springer
Page : 0 pages
File Size : 50,8 Mb
Release : 2016-10-06
Category : Medical
ISBN : 3662519186
This book provides a comprehensive overview of the biological basis of renal tumors in childhood and the clinical approaches to their treatment. Recent advances in our understanding of the molecular genetics of Wilms and other renal tumors are placed in their clinical context, including the differing treatment approaches of immediate surgery or pre-operative chemotherapy. The challenges in applying this knowledge to improve risk stratification and to incorporate biologically targeted agents into front-line therapy are discussed. All of the authors are experts from Europe and North America and the book has been written specifically as an easy reference for the practising clinician and the research scientist. It lays the basis for understanding the future direction of clinical and translational research to improve outcomes in patients with childhood renal tumors and will prove indispensable for those treating or researching into these diseases.
Author : Brigitte Kaissling,W. Kriz
Publisher : Springer
Page : 126 pages
File Size : 44,5 Mb
Release : 1979-01-01
Category : Science
ISBN : 3540091459
Karl Peter stated in 1909 in his famous monograph, Untersuchungen iiber Bau und Entwicklung der Niere, that the rabbit has a simply structured kidney and without knowledge of it he would not have succeeded in understanding the structural organi zation of other more complicated kidneys. Even with today's advanced knowledge of kidney organization this statement is still valid. With regard to the histotopographic relations of tubules and vessels as well as to the ultrastructure, the rabbit kidney is more simply organized than other mammalian kidneys, for example the mouse kidney and especially the Psammomys kidney. The rabbit kidney essentially displays the basic pattern of a mammalian kidney. Therefore, a thorough knowledge of the morphology of the rabbit kidney is indispensable for investigating kidneys of other species. Another reason for extensively investigating the rabbit kidney is that it is the only kidney with tubules that can easily be isolated and, therefore, be used for in vitro experiments (Burg et al. , 1966). Many investigations using these techniques have been performed in the last decade (for references see corresponding chapters). Accordingly the different segments of the nephron are functionally best characterized in the rabbit kidney. The purpose of this paper is to supply the basis for good structural-functional correlations. 2 Material and Methods 2. 1 Light Microscopy The histologic and histotopographic observations are based on a study of the kidneys of a total of 25 male and female New Zealand rabbits (2500-4500 g body wt. ). . 2. 1.
Author : Neil N. Turner,Norbert Lameire,David J. Goldsmith,Christopher G. Winearls,Jonathan Himmelfarb,Giuseppe Remuzzi
Publisher : Oxford University Press
Page : 3045 pages
File Size : 48,6 Mb
Release : 2015-10-29
Category : Medical
ISBN : 9780191017650
This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts. The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field. This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasis throughout is on marrying advances in scientific research with clinical management. Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrology's position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence. This print edition of The Oxford Textbook of Clinical Nephrology comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.