Understanding Radiation Biology

Author : Kenneth Chadwick
Publisher : CRC Press
Page : 253 pages
File Size : 50,7 Mb
Release : 2019-11-15
Category : Medical
ISBN : 9781000733549

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Understanding Radiation Biology by Kenneth Chadwick Pdf

This book provides a qualitative and quantitative exploration of the action of radiation on living matter which leads to a complete and coherent interpretation of radiation biology. It takes readers from radiation-induced molecular damage in the nucleus of the cell and links this damage to cellular effects such as cell killing, chromosome aberrations and mutations before exploring organ damage, organism lethality and cancer induction. It also deals with radiological protection concepts and the difficulties of predicting the dose–effect relationship for low-dose and dose rate radiation risk. The book ends with separate chapters dealing with the effects of UV light exposure and risk classification of chemical mutagens, both of which are derived by logical extensions of the radiation model. This book will provide the basic foundations of radiation biology for undergraduate and graduate students in medical physics, biomedical engineering, radiological protection, medicine, radiology and radiography. Features Presents a comprehensive insight into radiation action on living matter Contains important implications for radiological protection and regulations Provides analytical methods for applications in radiotherapy

Author : Susan B Klein,Marc S Mendonca
Publisher : World Scientific
Page : 399 pages
File Size : 50,7 Mb
Release : 2023-01-04
Category : Medical
ISBN : 9789811257674

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Fundamentals Of Radiation Biology by Susan B Klein,Marc S Mendonca Pdf

Fundamentals of Radiation Biology presents a contemporary, comprehensive review of the interactions between ionizing radiations and biological materials, tracking the consequences to three inevitable endpoints: cell restitution, cell death, or cell transformation.The introductory narrative is followed by examination of larger scale phenomena including tissue responses to radiation injury, organ failure modes, and resultant human illness including cancer. Ultimately, Fundamentals of Radiation Biology considers circumstantial radiation incidents impacting biological systems including radiological terrorism and radiation pollution remediation. Chapters presenting an overview of carcinogenesis and radiation therapy techniques based in radiobiology discuss two significant expansions central to the concerns of the text.This book takes an unprecedented narrative approach to radiobiology; each chapter expands on the fundamentals surveyed previously to lead the reader steadily to a panorama of radiation biocomplexity. No biological event happens in isolation. Actions evoke reactions that alter structures and cause living systems to adapt. It also examines the components constituting mammalian radiation response machinery and correlates them with resultant physiological behaviors.

Author : Alison P. Casarett,American Institute of Biological Sciences
Publisher : Prentice Hall
Page : 392 pages
File Size : 55,5 Mb
Release : 1968
Category : Science
ISBN : UOM:39015003386375

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Radiation Biology by Alison P. Casarett,American Institute of Biological Sciences Pdf

Author : Sarah Baatout
Publisher : Springer Nature
Page : 687 pages
File Size : 48,5 Mb
Release : 2023-09-23
Category : Science
ISBN : 9783031188107

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Radiobiology Textbook by Sarah Baatout Pdf

This open access textbook focuses on the various aspects of radiobiology. The goal of radiobiological research is to better understand the effects of radiation exposure at the cellular and molecular levels in order to determine the impact on health. This book offers a unique perspective, by covering not only radiation biology but also radiation physics, radiation oncology, radiotherapy, radiochemistry, radiopharmacy, nuclear medicine, space radiation biology & physics, environmental and human radiation protection, nuclear emergency planning, molecular biology and bioinformatics, as well as the ethical, legal and social considerations related to radiobiology. This range of disciplines contributes to making radiobiology a broad and rather complex topic. This textbook is intended to provide a solid foundation to those interested in the basics and practice of radiobiological science. It is a learning resource, meeting the needs of students, scientists and medical staff with an interest in this rapidly evolving discipline, as well as a teaching tool, with accompanying teaching material to help educators.

Author : William A. Glass,Matesh N. Varma
Publisher : Springer Science & Business Media
Page : 512 pages
File Size : 51,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468476279

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Physical and Chemical Mechanisms in Molecular Radiation Biology by William A. Glass,Matesh N. Varma Pdf

The fundamental understanding of the production of biological effects by ionizing radiation may well be one of the most important scientific objectives of mankind; such understanding could lead to the effective and safe utilization of the nuclear energy option. In addition, this knowledge will be of immense value in such diverse fields as radiation therapy and diagnosis and in the space program. To achieve the above stated objective, the U. S. Department of Energy (DOE) and its predecessors embarked upon a fundamental interdisciplinary research program some 35 years ago. A critical component of this program is the Radiological and Chemical Physics Program (RCPP). When the RCPP was established, there was very little basic knowledge in the fields of physics, chemistry, and biology that could be directly applied to understanding the effects of radiation on biological systems. Progress of the RCPP program in its first 15 years was documented in the proceedings of a conference held at Airlie, Virginia, in 1972. At this conference, it was clear that considerable progr:ess had been made in research on the physical and chemical processes in well-characterized systems that could be used to understand biological effects. During this period of time, most physical knowledge was obtained for the gas phase because the technology and instru mentation had not progressed to the point that measurements could be made in liquids more characteristic of biological materials.

Author : James Mannie Shuler
Publisher : Universal-Publishers
Page : 121 pages
File Size : 53,9 Mb
Release : 2006
Category : Medical
ISBN : 9781581129076

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Understanding Radiation Science by James Mannie Shuler Pdf

The purpose of Understanding Radiation Science: Basic Nuclear and Health Physics is to provide the reader a basic understanding of radiation science. Therefore, basic nuclear physics and health physics principles are presented through chapters on atomic structure, types of radiation, terminology and units, radiation biology, exposure and controls, background radiation, personnel monitoring, and radiation instrumentation. The book concludes with chapters on historical events and definitions. This book provides introductory information for students starting their education in nuclear physics, health physics and nuclear engineering. The material covered in this book is appropriate for all types of radiation workers. Persons studying to take the health physics certification exam, radiation protection technologist exam, or the certifying examinations to become radiologic technologists, radiation therapy technologists, ultrasound technologists, or nuclear medicine technologists will find this information most useful.

Author : Institute of Medicine,Committee to Study the Feasibility of, and Need for, Epidemiologic Studies of Adverse Reproductive Outcomes in the Families of Atomic Veterans
Publisher : National Academies Press
Page : 107 pages
File Size : 48,6 Mb
Release : 1995-07-17
Category : Medical
ISBN : 9780309176118

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Adverse Reproductive Outcomes in Families of Atomic Veterans by Institute of Medicine,Committee to Study the Feasibility of, and Need for, Epidemiologic Studies of Adverse Reproductive Outcomes in the Families of Atomic Veterans Pdf

Over the past several decades, public concern over exposure to ionizing radiation has increased. This concern has manifested itself in different ways depending on the perception of risk to different individuals and different groups and the circumstances of their exposure. One such group are those U.S. servicemen (the "Atomic Veterans" who participated in the atmospheric testing of nuclear weapons at the Nevada Test Site or in the Pacific Proving Grounds, who served with occupation forces in or near Hiroshima and Nagasaki, or who were prisoners of war in or near those cities at the time of, or shortly after, the atomic bombings. This book addresses the feasibility of conducting an epidemiologic study to determine if there is an increased risk of adverse reproductive outcomes in the spouses, children, and grandchildren of the Atomic Veterans.

Author : Donald J. Pizzarello
Publisher : CRC Press
Page : 311 pages
File Size : 51,6 Mb
Release : 2020-04-15
Category : Medical
ISBN : 9781000693416

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Radiation Biology by Donald J. Pizzarello Pdf

First Published in 1991, this book offers a full, comprehensive guide into the aspects of radiation and how it affects our bodies. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for Students of Radiology, and other practitioners in their respective fields.

Author : Charles A. Kelsey,Philip H. Heintz,Gregory D. Chambers,Daniel J. Sandoval,Natalie L. Adolphi,Kimberly S. Paffett
Publisher : John Wiley & Sons
Page : 341 pages
File Size : 53,7 Mb
Release : 2014-02-10
Category : Medical
ISBN : 9780470551776

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Radiation Biology of Medical Imaging by Charles A. Kelsey,Philip H. Heintz,Gregory D. Chambers,Daniel J. Sandoval,Natalie L. Adolphi,Kimberly S. Paffett Pdf

This book provides a thorough yet concise introduction to quantitative radiobiology and radiation physics, particularly the practical and medical application. Beginning with a discussion of the basic science of radiobiology, the book explains the fast processes that initiate damage in irradiated tissue and the kinetic patterns in which such damage is expressed at the cellular level. The final section is presented in a highly practical handbook style and offers application-based discussions in radiation oncology, fractionated radiotherapy, and protracted radiation among others. The text is also supplemented by a Web site.

Author : Leroy G. Augenstein,Ronald Mason,Max Zelle
Publisher : Academic Press
Page : 382 pages
File Size : 43,9 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483282404

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Advances in Radiation Biology by Leroy G. Augenstein,Ronald Mason,Max Zelle Pdf

Advances in Radiation Biology, Volume 2, reflects a continuing effort to provide wide-ranging analyses of progress in various phases of radiation research. The articles cover a spectrum of topics varying from the initial physical events which allow us to discriminate color, to the chemical and biological processes which determine the extent and permanence of radiation damage, and finally to the role of genetic control and damage in determining the fate of irradiated cells. The basic emphasis of the articles also varies. In some, the main attempt is to review extensively the available data so as to evaluate the possible contributions of various mechanisms to a given phenomenon. One article is devoted an evaluation of one physical approach which appears to be a promising way of understanding color perception. These different treatments should be of value not only to the researcher but also to the student, inasmuch as each approach is invariably dictated by the state of the art in the area being covered.

Author : A. H. W. Nias
Publisher : Unknown
Page : 364 pages
File Size : 49,8 Mb
Release : 1990-11-02
Category : Medical
ISBN : UOM:39015022253176

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Introduction to Radiobiology by A. H. W. Nias Pdf

Provides an introduction to quantitative radiobiology with emphasis on practical aspects of the subject. Readers will gain a ready understanding of both the very fast processes which initiate damage in irradiated tissue and the kinetic patterns in which such damage is expressed at the cellular level. Among the topics considered are reparable damage, densely ionizing radiation, normal and malignant cells and whole body regulation. These and other aspects of radiation biology are described in detail at a level appropriate to readers with a basic knowledge of mammalian cell biology.

Author : John Lett
Publisher : Academic Press
Page : 336 pages
File Size : 46,9 Mb
Release : 2012-12-02
Category : Health & Fitness
ISBN : 9780323155465

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Advances in Radiation Biology V14 by John Lett Pdf

Advances in Radiation Biology, Volume 14: Relative Radiation Sensitivities of Human Organ Systems, Part II focuses on radiation sensitivities of particular human organ systems. The sensitivities are then assessed based on the severity and the rapidity in which the effects of radiation manifest. The opening chapter surveys the clinical and experimental data on approaches toward the prevention of bladder complications in clinical radiotherapy. A discussion on HeLa cells, which are of special importance in human cervical cancer therapy, is then presented. In presenting this topic, this book emphasizes radiation sensitivity and radiobiology of tumors of the cervix of the female genital tract. Chapter 3 briefly covers imaging techniques for hypothalamic-pituitary dysfunction diagnosis and introduces hormonal therapy for remarkable improvements in both physical and mental status of patients. The subsequent chapters discuss basic radiobiology of the thyroid in experimental animal and the late effects of therapeutic and low-level radiation in humans. The radiation damages in bone and cartilage and the changes occurring in the various types of vessels during radiation therapy are also discussed. Chapter 7 presents the basic biology of spermatogenesis, as it applies to the understanding of radiation effects. This chapter also explains the studies of rodents, as it applies to subhuman primates and to man. Moreover, it considers as well the mechanisms of radiation damage to the testis, as elucidated by experimental studies of rodents and subhuman primates. Finally, it presents the limited data available on man and discusses these data in terms of the biology of the system known from experimental studies. The concluding chapter describes the features of radiation-induced hepatic injury, ranging from asymptomatic biochemical or a radiographic abnormality to fulminant, fatal hepatic failure. Radiation biologists will greatly benefit from this book, especially those who are involved in dose fractionation in radiation therapy.

Author : United States. Department of Energy. Technical Information Center
Publisher : Unknown
Page : 740 pages
File Size : 44,9 Mb
Release : 1978
Category : Radiation
ISBN : UOM:39015095115914

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Low-level Radiation by United States. Department of Energy. Technical Information Center Pdf

Author : Donald J. Pizzarello,Richard L. Witcofski
Publisher : Unknown
Page : 170 pages
File Size : 50,9 Mb
Release : 1975
Category : Science
ISBN : UCR:31210001553138

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Basic Radiation Biology by Donald J. Pizzarello,Richard L. Witcofski Pdf

Author : Eric J. Hall,Amato J. Giaccia
Publisher : Lippincott Williams & Wilkins
Page : 908 pages
File Size : 50,8 Mb
Release : 2012-03-28
Category : Medical
ISBN : 9781451154184

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Radiobiology for the Radiologist by Eric J. Hall,Amato J. Giaccia Pdf

In print since 1972, this seventh edition of Radiobiology for the Radiologist is the most extensively revised to date. It consists of two sections, one for those studying or practicing diagnostic radiolo, nuclear medicine and radiation oncology; the other for those engaged in the study or clinical practice of radiation oncology--a new chapter, on radiologic terrorism, is specifically for those in the radiation sciences who would manage exposed individuals in the event of a terrorist event. The 17 chapters in Section I represent a general introduction to radiation biology and a complete, self-contained course especially for residents in diagnostic radiology and nuclear medicine that follows the Syllabus in Radiation Biology of the RSNA. The 11 chapters in Section II address more in-depth topics in radiation oncology, such as cancer biology, retreatment after radiotherapy, chemotherapeutic agents and hyperthermia. Now in full color, this lavishly illustrated new edition is replete with tables and figures that underscore essential concepts. Each chapter concludes with a "summary of pertinent conclusions" to facilitate quick review and help readers retain important information.