Physical And Chemical Mechanisms In Molecular Radiation Biology

Author : William A. Glass,Matesh N. Varma
Publisher : Springer Science & Business Media
Page : 512 pages
File Size : 46,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468476279

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Physical and Chemical Mechanisms in Molecular Radiation Biology by William A. Glass,Matesh N. Varma Pdf

The fundamental understanding of the production of biological effects by ionizing radiation may well be one of the most important scientific objectives of mankind; such understanding could lead to the effective and safe utilization of the nuclear energy option. In addition, this knowledge will be of immense value in such diverse fields as radiation therapy and diagnosis and in the space program. To achieve the above stated objective, the U. S. Department of Energy (DOE) and its predecessors embarked upon a fundamental interdisciplinary research program some 35 years ago. A critical component of this program is the Radiological and Chemical Physics Program (RCPP). When the RCPP was established, there was very little basic knowledge in the fields of physics, chemistry, and biology that could be directly applied to understanding the effects of radiation on biological systems. Progress of the RCPP program in its first 15 years was documented in the proceedings of a conference held at Airlie, Virginia, in 1972. At this conference, it was clear that considerable progr:ess had been made in research on the physical and chemical processes in well-characterized systems that could be used to understand biological effects. During this period of time, most physical knowledge was obtained for the gas phase because the technology and instru mentation had not progressed to the point that measurements could be made in liquids more characteristic of biological materials.

Author : Raymond D. Cooper,Robert Winfield Wood
Publisher : Unknown
Page : 340 pages
File Size : 52,7 Mb
Release : 1974
Category : Radiation
ISBN : UOM:39015004508183

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Physical Mechanisms in Radiation Biology by Raymond D. Cooper,Robert Winfield Wood Pdf

Author : Glyn O. Phillips
Publisher : Unknown
Page : 558 pages
File Size : 54,5 Mb
Release : 1968
Category : Biophysics
ISBN : UOM:39015004381516

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Energetics and Mechanisms in Radiation Biology by Glyn O. Phillips Pdf

Author : John T. Lett,Howard Adler
Publisher : Academic Press
Page : 492 pages
File Size : 42,7 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483281896

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Advances in Radiation Biology by John T. Lett,Howard Adler Pdf

Advances in Radiation Biology, Volume 9, provides an overview of the state of knowledge in radiation biology. The book contains nine chapters and begins with a study on the ways in which physical and chemical agents might trigger "regulatory dysfunction" and how these agents might interact with each other. This is followed by separate chapters on the mechanisms underlying changes in vascular function after doses of radiation in the therapeutic range and their role in the development of late effects in normal tissues; the future of hypoxic cell sensitizers in the clinical setting; DNA strand break formation by ionizing radiation; and major pathways which result in radiation-induced loss of cellular proliferative capacity. Subsequent chapters deal with the solid-state radiation chemistry of DNA; radiosensitivity of proliferating mammalian cells; the use of microwave/radiofrequency energy cancer treatment; and the decline of basic radiobiology.

Author : Leroy G. Augenstein,Ronald Mason,Max Zelle
Publisher : Academic Press
Page : 382 pages
File Size : 44,8 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483282404

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Advances in Radiation Biology by Leroy G. Augenstein,Ronald Mason,Max Zelle Pdf

Advances in Radiation Biology, Volume 2, reflects a continuing effort to provide wide-ranging analyses of progress in various phases of radiation research. The articles cover a spectrum of topics varying from the initial physical events which allow us to discriminate color, to the chemical and biological processes which determine the extent and permanence of radiation damage, and finally to the role of genetic control and damage in determining the fate of irradiated cells. The basic emphasis of the articles also varies. In some, the main attempt is to review extensively the available data so as to evaluate the possible contributions of various mechanisms to a given phenomenon. One article is devoted an evaluation of one physical approach which appears to be a promising way of understanding color perception. These different treatments should be of value not only to the researcher but also to the student, inasmuch as each approach is invariably dictated by the state of the art in the area being covered.

Author : Hermann Dertinger,Horst Jung
Publisher : Springer Science & Business Media
Page : 246 pages
File Size : 48,7 Mb
Release : 2013-11-09
Category : Science
ISBN : 9781468462470

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Molecular Radiation Biology by Hermann Dertinger,Horst Jung Pdf

There can hardly be any doubt that radiation will continue to be an im portant factor in our lives. Present and future advances in atomic tech nology urgently require further work on research and development in the field of radiation biology if the maximum benefit is to be obtained at minimal risk from the various kinds of radiation that form a major by product of nuclear processes. Consequently, it is also necessary to prepare students and younger scientists for doing such work. The present book originates from teaching experience gained in lectures, seminars, and discussion groups started by the undersigned in 1957 and more recently held together with Drs. Dertinger and Jung. The friendly comments given to the German edition made us feel that it might be worth while to put the results of our efforts at the disposal of those to whom English is more familiar. In agreement with the view, based on well-known facts, that most if not aIl of the more striking practical achievements have resulted from patient and careful investigations into some basic problem, the book aims at introducing the reader to the methods of thought and experiment used in molecular radiation biology as weIl as to the results obtained thereby.

Author : G. Ahnström
Publisher : Springer
Page : 416 pages
File Size : 54,6 Mb
Release : 1978
Category : Science
ISBN : UOM:39015004350727

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Effects of Ionizing Radiation on DNA by G. Ahnström Pdf

Author : I︠U︡riĭ Borisovich Kudri︠a︡shov
Publisher : Nova Publishers
Page : 372 pages
File Size : 55,7 Mb
Release : 2008
Category : Science
ISBN : 1600212808

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Radiation Biophysics (ionizing Radiations) by I︠U︡riĭ Borisovich Kudri︠a︡shov Pdf

The book is concerned with features analysis of radiation damage to living matter at different levels of its organisation, beginning from the molecular level. The general theory of the mechanisms of biological action of radiation based on four logically connected principles of radiation biology is presented for the first time. The book contains abundant material on primary and secondary processes of the response of living systems to radiation, the mechanisms of direct and indirect action of radiation through radiolysis of water and lipids; a detailed consideration of the theory of targets (DNA and biological membranes) and the problems of high- and low-dose irradiation in the context of present-day. The systemic response of the cell to irradiation (oxidative stress, endogenous background radioresistance, damage and repair of biological membranes and DNA, systemic protection against radiation) is approximated. Presentation of these important problems is preceded by an up-to-date evaluation of some aspects regarding dosimetry of ionising radiation.

Author : Leroy G. Augenstein,Ronald Mason,Henry Quastler
Publisher : Academic Press
Page : 296 pages
File Size : 50,8 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483282398

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Advances in Radiation Biology by Leroy G. Augenstein,Ronald Mason,Henry Quastler Pdf

Advances in Radiation Biology, Volume 1, provides an overview of the state of knowledge in radiation biology. The book contains six chapters and opens with a review some of the recent work bearing on the nature of the radicals produced in water and on the rates of some of the reactions of the radicals. It also comments on some of the applications of the radical model which have been made. These are followed by a chapter on the process of photosynthesis, covering light absorption and emission by pigments, electromagnetic energy transfer among and between pigment molecules, and the (physical) transfer and migration of electronic charge. Subsequent chapters deal with the effects of tritium irradiation on cells; the effects of small doses of ionizing radiation; the radiation chemical reactions of the amino acids; and the nature of temperature effects on enzyme inactivation by various radiations.

Author : Jürgen Kiefer
Publisher : Unknown
Page : 470 pages
File Size : 41,5 Mb
Release : 1990
Category : Radiation
ISBN : UOM:39015018979453

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Biological Radiation Effects by Jürgen Kiefer Pdf

Author : Raymond D. Cooper,Robert W. Wood
Publisher : Unknown
Page : 332 pages
File Size : 48,5 Mb
Release : 1974
Category : Electronic
ISBN : OCLC:257985564

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Physical Mechanisms in Radiation Biology by Raymond D. Cooper,Robert W. Wood Pdf

Author : Matesh N. Varma,Aloke Chatterjee
Publisher : Springer Science & Business Media
Page : 262 pages
File Size : 46,6 Mb
Release : 2013-11-11
Category : Science
ISBN : 9781475797886

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Computational Approaches in Molecular Radiation Biology by Matesh N. Varma,Aloke Chatterjee Pdf

The Office of Health and Environmental Research (OHER) has supported and continues to support development of computational approaches in biology and medicine. OHER's Radiological and Chemical Physics Program initiated development of computational approaches to determine the effects produced by radiation of different quality (such as high energy electrons, protons, helium and other heavy ions, etc. ) in a variety of materials of biological interest-such as water, polymers and DNA; these include molecular excitations and sub-excitations and the production of ionization and their spatial and temporal distribution. In the past several years, significant advances have been made in computational methods for this purpose. In particular, codes based on Monte Carlo techniques have ·been developed that provide a realistic description of track-structure produced by charged particles. In addition, the codes have become sufficiently sophisticated so that it is now possible to calculate the spatial and temporal distribution of energy deposition patterns in small volumes of subnanometer and nanometer dimensions. These dimensions or resolution levels are relevant for our understanding of mechanisms at the molecular level by which radiations affect biological systems. Since the Monte Carlo track structure codes for use in radiation chemistry and radiation biology are still in the developmental stage, a number of investigators have been exploring different strategies for improving these codes.

Author : Sarah Baatout
Publisher : Springer Nature
Page : 687 pages
File Size : 47,5 Mb
Release : 2023-09-23
Category : Science
ISBN : 9783031188107

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Radiobiology Textbook by Sarah Baatout Pdf

This open access textbook focuses on the various aspects of radiobiology. The goal of radiobiological research is to better understand the effects of radiation exposure at the cellular and molecular levels in order to determine the impact on health. This book offers a unique perspective, by covering not only radiation biology but also radiation physics, radiation oncology, radiotherapy, radiochemistry, radiopharmacy, nuclear medicine, space radiation biology & physics, environmental and human radiation protection, nuclear emergency planning, molecular biology and bioinformatics, as well as the ethical, legal and social considerations related to radiobiology. This range of disciplines contributes to making radiobiology a broad and rather complex topic. This textbook is intended to provide a solid foundation to those interested in the basics and practice of radiobiological science. It is a learning resource, meeting the needs of students, scientists and medical staff with an interest in this rapidly evolving discipline, as well as a teaching tool, with accompanying teaching material to help educators.

Author : Manoj Shukla,Jerzy Leszczynski
Publisher : Springer Science & Business Media
Page : 677 pages
File Size : 44,7 Mb
Release : 2008-05-08
Category : Science
ISBN : 9781402081842

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Radiation Induced Molecular Phenomena in Nucleic Acids by Manoj Shukla,Jerzy Leszczynski Pdf

Comprehensive theoretical and experimental analysis of UV-radiation and low energy electron induced phenomena in nucleic acid bases (NABs) and base assemblies are presented in this book. NABs are highly photostable; the absorbed energy is dissipated in the form of ultrafast nonradiative decay. This book highlights the possible mechanisms of these phenomena which is important for all living species and discusses technical challenges in exploration of these processes.

Author : Association for Radiation Research
Publisher : Elsevier Science & Technology
Page : 530 pages
File Size : 42,7 Mb
Release : 1979
Category : Science
ISBN : UOM:39015016015144

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Radiation Biology and Chemistry by Association for Radiation Research Pdf