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Understanding The Interplay Between The Tumor Immune Microenvironment And Genetic Alterations In Thoracic Malignancies Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Understanding The Interplay Between The Tumor Immune Microenvironment And Genetic Alterations In Thoracic Malignancies book. This book definitely worth reading, it is an incredibly well-written.
Author : Giulia Pasello,Emanuela Felley-Bosco,Jordi Remon
Publisher : Frontiers Media SA
Page : 163 pages
File Size : 54,7 Mb
Release : 2022-03-28
Category : Medical
ISBN : 9782889748181
Author : Steven E. Schild, MD
Publisher : Demos Medical
Page : 0 pages
File Size : 48,7 Mb
Release : 2010-03-08
Category : Medical
ISBN : 1933864893
Thoracic Malignancies: Thoracic Malignancies is the first title in Radiation Medicine Rounds. These tumors take more lives than any others and they are among the most preventable of tumors. Thus it is crucial for the practitioner to be up-to-date on the latest insights regarding their management. Thoracic Malignancies addresses the multi-disciplinary nature of the care of these tumors. There is representation from radiation oncology, medical oncology, and surgery ensuring a well-rounded summarization of current practice. Included are chapters on lung cancer, esophageal cancer, and thymomas providing coverage of the vast majority of thoracic tumors. The multi-disciplinary nature of the articles provides readers with an up-to-date summary and a well-rounded review regarding these tumors and their care. Expert authors provide reviews and assessments of the most recent data and its implications for current clinical practice, along with insights into emerging new trends of importance for the near future. About the Series Radiation Medicine Rounds is an invited review publication providing a thorough analysis of new scientific, technologic, and clinical advances in all areas of radiation medicine. There is an emphasis throughout on multidisciplinary approaches to the specialty, as well as on quality and outcomes analysis. Published three times a year Radiation Medicine Rounds provides authoritative, thorough assessments of a wide range of œhot topics” and emerging new data for the entire specialty of radiation medicine. Features of Radiation Medicine Rounds include: Editorial board of nationally recognized experts across the spectrum of radiation medicine In-depth, up-to-date expert reviews and analysis of major new developments in all areas of Radiation Medicine Issues edited by an authority in specific subject area Focuses on major topics in Radiation Medicine with in-depth articles covering advances in radiation science radiation medicine technology, radiation medicine practice, and assessment of recent quality and outcomes studies Emphasizes multidisciplinary approaches to research and practice "
Author : Harvey Pass,David Ball,Giorgio Scagliotti
Publisher : Elsevier Health Sciences
Page : 960 pages
File Size : 52,5 Mb
Release : 2017-04-21
Category : Medical
ISBN : 9780323527842
Global experts, in conjunction with the International Association for the Study of Lung Cancer, bring you up to date with today’s best approaches to lung cancer diagnosis, treatment, and follow-up. IASLC Thoracic Oncology, 2nd Edition, keeps you abreast of the entire scope of this fast-changing field, from epidemiology to diagnosis to treatment to advocacy. Written in a straightforward, practical style for the busy clinician, this comprehensive, multidisciplinary title is a must-have for anyone involved in the care of patients with lung cancer and other thoracic malignancies. Offers practical, relevant coverage of basic science, epidemiology, pulmonology, medical and radiation oncology, surgery, pathology, palliative care, nursing, and advocacy. Provides authoritative guidance from the IASLC – the only global organization dedicated to the study of lung cancer. Includes new content on molecular testing, immunotherapy, early detection, staging and the IASLC staging system, surgical resection for stage I and stage II lung cancer, and stem cells in lung cancer. Features a new full-color design throughout, as well as updated diagnostic algorithms.
Author : American Association for Cancer Research
Publisher : CTI Meeting Technology
Page : 128 pages
File Size : 42,6 Mb
Release : 2018-04-10
Category : Electronic
ISBN : 9781370247707
Author : Bryan M. Burt
Publisher : Elsevier Health Sciences
Page : 137 pages
File Size : 49,5 Mb
Release : 2020-11-28
Category : Medical
ISBN : 9780323759656
This issue of Thoracic Surgery Clinics, guest edited by Dr. Bryan M. Burt, is devoted to Malignant Pleural Mesothelioma. Dr. Burt has assembled expert authors to review the following topics: Biomarkers for the Diagnosis and Monitoring of Malignant Pleural Mesothelioma; Taken Together: Effective Multimodal Approaches for Malignant Pleural Mesothelioma; Pleurectomy/Decortication for Malignant Pleural Mesothelioma; Preoperative Identification of Benefit from Surgery for Malignant Pleural Mesothelioma; The Role of Extrapleural Pneumonectomy in Malignant Pleural Mesothelioma; The Molecular Basis of Malignant Pleural Mesothelioma; Radiation Therapy for Malignant Pleural Mesothelioma; The Staging of Malignant Pleural Mesothelioma; Intraoperative Adjuncts for Malignant Pleural Mesothelioma: The Fourth Dimension; The Pathology of Malignant Pleural Mesothelioma; and more!
Author : Weimin Mao,Herbert Yu,Qibin Song,Kai Wang
Publisher : Frontiers Media SA
Page : 223 pages
File Size : 55,8 Mb
Release : 2022-11-28
Category : Medical
ISBN : 9782832507339
Author : Tim F. Greten
Publisher : Springer
Page : 167 pages
File Size : 49,9 Mb
Release : 2017-10-04
Category : Medical
ISBN : 9783319649580
In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.
Author : Gregory P. Kalemkerian, MD,Jessica S. Donington, MD,Elizabeth M. Gore, MD,Suresh S. Ramalingam, MD
Publisher : Springer Publishing Company
Page : 416 pages
File Size : 51,7 Mb
Release : 2016-11-28
Category : Medical
ISBN : 9781617052729
In many ways, the field of lung cancer research is leading the way in personalized oncologic care, with numerous new treatment strategies moving from clinical trials to standard clinical practice within the past 10 years; and, there are no indications of bench-to-bedside innovations slowing down. Handbook of Thoracic Oncology is a practical guide to the multidisciplinary management of patients with lung cancer and other thoracic malignancies. The content highlights the applications of both conventional and novel treatment strategies to the care of real-life patients with lung cancer. Unlike many oncology textbooks that exhaustively list studies of historical or failed approaches, this handbook focuses on the application of practical, current management options to specific patient subsets and the data that specifically support these strategies. The format is open and readable with bulleted points presenting overall treatment guidelines as well as more nuanced applications of these treatments to individual patient groups. The clear focus of this book is on the question that all oncologists ask themselves every day, “How do I take care of this person sitting in front of me?” This handbook is an indispensable guide for all oncologists and practitioners who regularly care for lung cancer patients and those suffering from mesothelioma, thymic tumors, and pulmonary neuro-endocrine tumors. Features: Delivers the need-to-know points of lung cancer screening, diagnosis and staging, and appropriate multidisciplinary management for all major thoracic malignancies Provides clinical pearls and treatment recommendations for patients who don’t ‘fit’ the standard guidelines Includes specific coverage on Management of Elderly and High-Risk Patients Prepares physicians to notice and eliminate common errors in clinical practice when managing patients with lung cancer and other thoracic tumors
Author : Yutaka Shimada,Katsuhiko Yanaga
Publisher : Springer
Page : 156 pages
File Size : 51,7 Mb
Release : 2017-11-29
Category : Medical
ISBN : 9789811064692
This volume focuses on the clinical applications of molecular diagnosis and targeted therapy from the viewpoint of oncologists specializing in specific organs. In addition, it discusses the role of molecular diagnosis and targeted therapy in the course of surgical treatment. Recent, rapid advances in molecular biology have shed new light on the mechanisms of cancer progression, and molecularly targeted drugs have been used to treat a variety of malignant diseases. For the diagnosis and precise treatment of cancer, analysis of the molecular background of the tumor is indispensable. However, there are both tumor-specific and comprehensive mechanisms involved in these processes. Accordingly, a firm grasp of molecular diagnosis and targeted therapies for different tumors is vital for clinicians and basic researchers alike. This book provides essential information and the latest findings on molecular diagnosis and targeted therapy for thoracic and gastrointestinal malignancies. Though primarily intended for clinical and basic oncologists, it also offers a useful guide for clinicians who are interested in this field and are considering getting started in molecular diagnosis and targeted therapy.
Author : Macfarlane Burnet
Publisher : Elsevier
Page : 289 pages
File Size : 44,9 Mb
Release : 2014-05-17
Category : Medical
ISBN : 9781483159225
Immunological Surveillance
Author : Ahmed Lasfar,Karine Cohen-Solal
Publisher : Unknown
Page : 128 pages
File Size : 51,8 Mb
Release : 2020
Category : Electronic
ISBN : 1789851467
Author : Kenneth O'Byrne,Valerie Rusch
Publisher : Oxford University Press
Page : 128 pages
File Size : 47,5 Mb
Release : 2006-11-16
Category : Medical
ISBN : 9780191566929
Malignant pleural mesothelioma, a malignancy due largely to asbestos exposure, represents an increasingly common challenge to clinical and medical oncologists, respiratory physicians, and cardiothoracic surgeons, as well as researchers in the field. The disease has yet to reach its peak and is expected to kill over 100,000 people worldwide. As malignant pleural mesothelioma gains in profile, Kenneth O'Byrne and Valerie Rusch present a comprehensive overview of the subject, aimed at all health care professionals who come into contact with patients with the disease. The book includes chapters on epidemiology, diagnosis, histopathology, radiology, surgery, chemotherapy, immune therapy, radiotherapy, and palliative medicine, written by an international team of contributors. A molecular biology section focuses on the carcinogenic effects of asbestos fibres and simian virus 40, angiogenesis and angiogenic growth factors, the immune response, and genetic abnormalities detected in the disease. Future therapies are also covered, as is a perspective on the distinct legal issues related to the disease. This highly-illustrated, full colour book provides the ultimate, timely resource on this devastating disease.
Author : Kapil Mehta,Zahid H. Siddik
Publisher : Springer Science & Business Media
Page : 372 pages
File Size : 54,8 Mb
Release : 2009-06-12
Category : Medical
ISBN : 9780387894454
It was estimated that in 2008, 1,437,180 patients would receive a new cancer diagnosisand 565,650individualswould die of cancer (Jemal et al. 2008).Since the vast majority of patients dying of cancer will have had anticancer therapy, both c- ventional chemotherapy and novel targeted therapy, it can be concluded that these patients are dying with drug resistant cancer. The term multidrug resistance is also apt – in that these patients die after having undergone multiple rounds of different and structurally unrelated cancer therapies. However, for some, the concept of m- tidrug resistance is a worn out idea, stemming from disappointment with the drug resistancereversalstrategiesthatwerecarriedoutinthe1990susingpumpinhibitors to block drug resistance mediated by P-glycoprotein, product of the MDR-1 gene. However, if one takes the larger de?nition – multidrug resistance as simultaneous resistance to multiple structurally unrelated anticancer therapies – its existence c- not be denied. The purpose of this book is to explore new concepts related to drug resistance in cancer, including resistance to the new molecularly targeted agents. Perhaps new terminology is needed for resistance that occurs following therapy with the targeted agents: Novel Targeted Agent Resistance (NTR). Alternatively, we can return to the original de?nition of multidrug resistance as simply the res- tance to multipleagents that occurs in the course of normalcancer progression.This resistance is likely to be mediated by many factors.
Author : Chen Chen,Kezhong Chen,Kai He
Publisher : Frontiers Media SA
Page : 130 pages
File Size : 49,9 Mb
Release : 2022-01-17
Category : Medical
ISBN : 9782889740437
Author : Patrik Andersson,Christian Ostheimer
Publisher : Frontiers Media SA
Page : 316 pages
File Size : 50,6 Mb
Release : 2019-12-27
Category : Electronic
ISBN : 9782889631612
The immune system harbors great potential for controlling and eliminating tumors. Recent developments in the field of immuno-oncology has led to unprecedented clinical benefits for a broad spectrum of solid tumors. However, immunotherapy (IT) approaches currently have several limitations including (i) low response rate; (ii) development of resistance and (iii) causing severe immune-related adverse effects (IrAEs), which underline the importance of adequate patient selection. Importantly, IT holds promising synergistic potential when combined with standard-of-care chemotherapy, radiotherapy (RT) and anti-angiogenic therapy (AAT) as part of multi-modal oncologic treatment regimes. Published data suggest that there are potential synergy between RT and AAT, which ultimately could help potentiate the response to IT. However, the complex interactions between RT and IT and/or AAT remain poorly understood. Many research questions including optimal timing, scheduling and dosing, as well as patient selection and side effects of combined therapy approaches, remain to be addressed. This Research Topic aims to give a comprehensive overview of the current field with particular emphasis on the future outlook of RT and AAT as complementary approaches to improve IT in solid tumors.
