Vivo

Author : Katy Börner
Publisher : Morgan & Claypool Publishers
Page : 181 pages
File Size : 50,5 Mb
Release : 2012
Category : Computers
ISBN : 9781608459933

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VIVO by Katy Börner Pdf

The world of scholarship is changing rapidly. Increasing demands on scholars, the growing size and complexity of questions and problems to be addressed, and advances in sophistication of data collection, analysis, and presentation require new approaches to scholarship. A ubiquitous, open information infrastructure for scholarship, consisting of linked open data, open-source software tools, and a community committed to sustainability are emerging to meet the needs of scholars today. This book provides an introduction to VIVO, http: //vivoweb.org/, a tool for representing information about research and researchers -- their scholarly works, research interests, and organizational relationships. VIVO provides an expressive ontology, tools for managing the ontology, and a platform for using the ontology to create and manage linked open data for scholarship and discovery. Begun as a project at Cornell and further developed by an NIH funded consortium, VIVO is now being established as an open-source project with community participation from around the world. By the end of 2012, over 20 countries and 50 organizations will provide information in VIVO format on more than one million researchers and research staff, including publications, research resources, events, funding, courses taught, and other scholarly activity. The rapid growth of VIVO and of VIVO-compatible data sources speaks to the fundamental need to transform scholarship for the 21st century. Table of Contents: Scholarly Networking Needs and Desires / The VIVO Ontology / Implementing VIVO and Filling It with Life / Case Study: University of Colorado at Boulder / Case Study: Weill Cornell Medical College / Extending VIVO / Analyzing and Visualizing VIVO Data / The Future of VIVO: Growing the Community

Author : Lawrence J. Berliner
Publisher : Springer Science & Business Media
Page : 670 pages
File Size : 44,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461500612

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In Vivo EPR (ESR) by Lawrence J. Berliner Pdf

In Vivo EPR (ESR) is a textbook on this relatively new subject in biomedical electron spin resonance. While a few chapters have appeared in special topics volumes in this series, this book covers the principles and theory, instrumentation as well as the latest applications at the time of its writing. The authors are world-renowned experts and pioneers in their fields. This book is divided into two major sections dealing with theory and instrumentation, and aspects of biochemistry, in vitro and in vivo applications. A significant amount of detail is devoted to clinical applications and the problems and pitfalls encountered in in vivo spectroscopy and imaging. Key Features: -History of In Vivo EPR, -Principles of Imaging-Theory and Instrumentation, -Time-domain Radio Frequency EPR Imaging, -The Measurement of Oxygen In Vivo Using In Vivo EPR Techniques, -Potential Medical (Clinical) Applications of EPR, -Combining NMR and EPR/ESR for In Vivo Experiments.

Author : Anonim
Publisher : Simon and Schuster
Page : 82 pages
File Size : 40,5 Mb
Release : 2021-07-06
Category : Juvenile Fiction
ISBN : 9781534465824

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Vivo Movie Novelization by Anonim Pdf

Vivo, the highly anticipated animated movie-musical with original songs by Lin-Manuel Miranda, will soon be dancing onto Netflix! This funny and heartfelt novelization features eight pages of images from the film and is sure to have readers singing and laughing along! Meet Vivo and experience his passion for music. Join him as he travels from Havana to Miami on a musical journey. TM & © 2021 Sony Pictures Animation Inc. All Rights Reserved.

Author : Anonim
Publisher : CUP Archive
Page : 320 pages
File Size : 40,8 Mb
Release : 1964
Category : Host-parasite relationships
ISBN : 8210379456XXX

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Microbial Behaviour, 'in Vivo' and 'in Vitro' by Anonim Pdf

Author : Lawrence J. Berliner,Jacques Reuben
Publisher : Springer Science & Business Media
Page : 345 pages
File Size : 55,9 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781475794779

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In Vivo Spectroscopy by Lawrence J. Berliner,Jacques Reuben Pdf

In vivo nuclear magnetic and electron spin resonance spectroscopy is concerned, inter alia, with the noninvasive observation of metabolic changes in living systems, including animals and humans. Typically, the physiologi cal (or pathological) state of an organ or tissue is monitored. This multi faceted approach was developed during the 1980s. It is still a research technique, but will undoubtedly become a clinical tool. We are proud to present this volume (the eleventh of our series) in which some of the pioneers in this area summarize their contributions and review related literature. Bolinger and Lenkinski describe a variety of localization methods suitable for clinical applications of NMR spectroscopy. Schleich, Caines, and Rydzewski summarize their contributions to approaches involving off-resonance rotating frame relaxation and critically compare these with other NMR techniques that may yield similar information. Chang and James outline their approach and share their experience with the technical aspects 1 31 of H and P NMR spectroscopy and spatially localized spectroscopy in studies of brain ischemia. Sodium plays an important role in living systems, a key aspect being the large gradient between intra- and extracellular concentrations of sodium that is maintained by a variety of transport mechanisms. Miller and Elgavish give us a comprehensive review of an important research tool in this 23 area- Na NMR spectroscopy as aided by shift reagents.

Author : Robin A. de Graaf
Publisher : John Wiley & Sons
Page : 584 pages
File Size : 52,8 Mb
Release : 2018-12-11
Category : Science
ISBN : 9781119382577

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In Vivo NMR Spectroscopy by Robin A. de Graaf Pdf

Presents basic concepts, experimental methodology and data acquisition, and processing standards of in vivo NMR spectroscopy This book covers, in detail, the technical and biophysical aspects of in vivo NMR techniques and includes novel developments in the field such as hyperpolarized NMR, dynamic 13C NMR, automated shimming, and parallel acquisitions. Most of the techniques are described from an educational point of view, yet it still retains the practical aspects appreciated by experimental NMR spectroscopists. In addition, each chapter concludes with a number of exercises designed to review, and often extend, the presented NMR principles and techniques. The third edition of In Vivo NMR Spectroscopy: Principles and Techniques has been updated to include experimental detail on the developing area of hyperpolarization; a description of the semi-LASER sequence, which is now a method of choice; updated chemical shift data, including the addition of 31P data; a troubleshooting section on common problems related to shimming, water suppression, and quantification; recent developments in data acquisition and processing standards; and MatLab scripts on the accompanying website for helping readers calculate radiofrequency pulses. Provide an educational explanation and overview of in vivo NMR, while maintaining the practical aspects appreciated by experimental NMR spectroscopists Features more experimental methodology than the previous edition End-of-chapter exercises that help drive home the principles and techniques and offer a more in-depth exploration of quantitative MR equations Designed to be used in conjunction with a teaching course on the subject In Vivo NMR Spectroscopy: Principles and Techniques, 3rd Edition is aimed at all those involved in fundamental and/or diagnostic in vivo NMR, ranging from people working in dedicated in vivo NMR institutes, to radiologists in hospitals, researchers in high-resolution NMR and MRI, and in areas such as neurology, physiology, chemistry, and medical biology.

Author : In-Young Choi,Rolf Gruetter
Publisher : Springer Science & Business Media
Page : 1168 pages
File Size : 54,6 Mb
Release : 2012-03-08
Category : Medical
ISBN : 9781461417880

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Neural Metabolism In Vivo by In-Young Choi,Rolf Gruetter Pdf

From the preface: “Neural Metabolism In Vivo aims to provide a comprehensive overview of neurobiology by presenting the basic principles of up-to-date and cutting-edge technology, as well as their application in assessing the functional, morphological and metabolic aspects of the brain. Investigation of neural activity of the living brain via neurovascular coupling using multimodal imaging techniques extended our understanding of fundamental neurophysiological mechanisms, regulation of cerebral blood flow in connection to neural activity and the interplay between neurons, astrocytes and blood vessels. Constant delivery of glucose and oxygen for energy metabolism is vital for brain function, and the physiological basis of neural activity can be assessed through measurements of cerebral blood flow and consumption of glucose and oxygen.... This book presents the complex physiological and neurochemical processes of neural metabolism and function in response to various physiological conditions and pharmacological stimulations. Neurochemical detection technologies and quantitative aspects of monitoring cerebral energy substrates and other metabolites in the living brain are described under the “Cerebral metabolism of antioxidants, osmolytes and others in vivo” section. Altogether, the advent of new in vivo tools has transformed neuroscience and neurobiology research, and demands interdisciplinary approaches as each technology could only approximate a very small fraction of the true complexity of the underlying biological processes. However, translational values of the emerging in vivo methods to the application of preclinical to clinical studies cannot be emphasized enough. Thus, it is our hope that advances in our understanding of biochemical, molecular, functional and physiological processes of the brain could eventually help people with neurological problems, which are still dominated by the unknowns.” -- In-Young Choi and Rolf Gruetter

Author : Margarida Barroso,Xavier Intes
Publisher : CRC Press
Page : 371 pages
File Size : 41,5 Mb
Release : 2020-12-03
Category : Science
ISBN : 9781351704502

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Imaging from Cells to Animals In Vivo by Margarida Barroso,Xavier Intes Pdf

Imaging from Cells to Animals In Vivo offers an overview of optical imaging techniques developed over the past two decades to investigate biological processes in live cells and tissues. It comprehensively covers the main imaging approaches used as well as the application of those techniques to biological investigations in preclinical models. Among the areas covered are cell metabolism, receptor-ligand interactions, membrane trafficking, cell signaling, cell migration, cell adhesion, cytoskeleton and other processes using various molecular optical imaging techniques in living organisms, such as mice and zebrafish. Features Brings together biology and advanced optical imaging techniques to provide an overview of progress and modern methods from microscopy to whole body imaging. Fills the need for a comprehensive view of application-driven development and use of new tools to ask new biological questions in the context of a living system. Includes basic chapters on key methods and instrumentation, from fluorescence microscopy and imaging to endoscopy, optical coherence tomography and super-resolution imaging. Discusses approaches at different length scales and biomedical applications to the study of single cell, whole organ, and whole organism behavior. Addresses the impact on discovery, such as cellular function as implicated in human disease and translational medicine, for example in cancer diagnosis.

Author : Daniel M. Spielman,Keshav Datta
Publisher : John Wiley & Sons
Page : 293 pages
File Size : 47,9 Mb
Release : 2024-04-02
Category : Science
ISBN : 9781394233113

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Fundamentals of In Vivo Magnetic Resonance by Daniel M. Spielman,Keshav Datta Pdf

Fundamentals of In Vivo Magnetic Resonance Authoritative reference explaining why and how the most important, radiation-free technique for elucidating tissue properties in the body works In Vivo Magnetic Resonance helps readers develop an understanding of the fundamental physical processes that take place inside the body that can be probed by magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS), uniquely bridging the gap between the physics of magnetic resonance (MR) image formation and the in vivo processes that influence the detected signals, thereby equipping the reader with the mathematical tools essential to study the spin interactions leading to various contrast mechanisms. With a focus on clinical relevance, this book equips readers with practical knowledge that can be directly applied in medical settings, enabling informed decision-making and advancements in the field of medical imaging. The material arises from the lecture notes for a Stanford University Department of Radiology course taught for over 15 years. Aided by clever illustrations, the book takes a step-by-step approach to explain complex concepts in a comprehensible manner. Readers can test their understanding by working on approximately 60 sample problems. Written by two highly qualified authors with significant experience in the field, In Vivo Magnetic Resonance includes information on: The fundamental imaging equations of MRI Quantum elements of magnetic resonance, including linear vector spaces, Dirac notation, Hilbert Space, Liouville Space, and associated mathematical concepts Nuclear spins, covering external and internal interactions, chemical shifts, dipolar coupling, J-coupling, the spin density operator, and the product operator formalism In vivo MR spectroscopy methods MR relaxation theory and the underlying sources of image contrast accessible via modern clinical MR imaging techniques With comprehensive yet accessible coverage of the subject and a wealth of learning resources included throughout, In Vivo Magnetic Resonance is an ideal text for graduate students in the fields of physics, biophysics, biomedical physics, and materials science, along with lecturers seeking classroom aids.

Author : Shinichi Ohno,Nobuhiko Ohno,Nobuo Terada
Publisher : Springer
Page : 300 pages
File Size : 50,8 Mb
Release : 2015-11-26
Category : Medical
ISBN : 9784431557234

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In Vivo Cryotechnique in Biomedical Research and Application for Bioimaging of Living Animal Organs by Shinichi Ohno,Nobuhiko Ohno,Nobuo Terada Pdf

This book focuses on actual morphofunctional findings of cells and tissues in living animal organs. Medical and biological scientists need to know the real in vivo morphology and immunolocalization of the molecular components in living animal organs. Recently, the live imaging of cells and tissues of animals with fluorescence-labeled proteins by gene manipulation has become more and more popular in biological fields. Current research, meanwhile, has revealed that immunohistochemical or morphological studies exclusively depend on living animal organs. The cryotechnique is one of the most useful tools for immunohistochemistry and bioimaging of animal organs. This book describes the epoch-making cryotechnique originally developed by the editors. The book also makes the management of living animal morphology more accessible not only for biomedical researchers but also for clinical doctors, providing a valuable resource work on the current perspectives of in vivo morphology.

Author : Vasilis Ntziachristos,Anne Leroy-Willig,Bertrand Tavitian
Publisher : John Wiley & Sons
Page : 388 pages
File Size : 54,9 Mb
Release : 2007-08-20
Category : Science
ISBN : 0470029587

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Textbook of in vivo Imaging in Vertebrates by Vasilis Ntziachristos,Anne Leroy-Willig,Bertrand Tavitian Pdf

This book describes the new imaging techniques being developed to monitor physiological, cellular and subcellular function within living animals. This exciting field of imaging science brings together physics, chemistry, engineering, biology and medicine to yield powerful and versatile imaging approaches. By combining advanced non-invasive imaging technologies with new mechanisms for visualizing biochemical events and protein and gene function, non-invasive vertebrate imaging enables the in vivo study of biology and offers rapid routes from basic discovery to drug development and clinical application. Combined with the availability of an increasing number of animal models of human disease, and the ability to perform longitudinal studies of disease evolution and of the long-term effects of therapeutic procedures, this new technology offers the next generation of tools for biomedical research. Well illustrated, largely in colour, the book reviews the most common and technologically advanced methods for vertebrate imaging, presented in a clear, comprehensive format. The basic principles are described, followed by several examples of the use of imaging in the study of living multicellular organisms, concentrating on small animal models of human diseases. The book illustrates: The types of information that can be obtained with modern in vivo imaging; The substitution of imaging methods for more destructive histological techniques; The advantages conferred by in vivo imaging in building a more accurate picture of the response of tissues to stimuli over time while significantly reducing the number of animals required for such studies. Part 1 describes current techniques in in vivo imaging, providing specialists and laboratory scientists from all disciplines with clear and helpful information regarding the tools available for their specific research field. Part 2 looks in more detail at imaging organ development and function, covering the brain, heart, lung and others. Part 3 describes the use of imaging to monitor various new types of therapy, following the reaction in an individual organism over time, e.g. after gene or cell therapy. Most chapters are written by teams of physicists and biologists, giving a balanced coherent description of each technique and its potential applications.

Author : Roger Narayan
Publisher : Woodhead Publishing
Page : 224 pages
File Size : 54,9 Mb
Release : 2016-11-11
Category : Medical
ISBN : 9780081006047

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Monitoring and Evaluation of Biomaterials and their Performance In Vivo by Roger Narayan Pdf

Monitoring and Evaluation of Biomaterials and Their Performance In Vivo provides essential information for scientists and researchers who need to assess and evaluate performance, monitor biological responses, gauge efficacy, and observe changes over time. Crucially, it also enables the optimization of design for future biomaterials and implants. This book presents readers with comprehensive coverage of the topic of in vivo monitoring of medical implants and biomaterials. Contains a specific focus on monitoring and evaluation of biomaterials in vivo Multi-faceted coverage of materials function and performance Focuses on a range of implants and subsequent bodily reactions

Author : Anonim
Publisher : Academic Press
Page : 464 pages
File Size : 55,7 Mb
Release : 2009-02-12
Category : Science
ISBN : 0080921663

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Angiogenesis: In Vivo Systems by Anonim Pdf

Understanding how angiogenesis "works" and how to control it will have massive implications on the management, treatments, and ultimately the prevention of many common (and not so common) diseases. Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance of angiogenesis modulators. In many serious disease states, however, the body loses control over angiogenesis. Diseases that are angiogenesis-dependent result when blood vessels either grow excessively or insufficiently. * Tried-and-tested techniques written by researchers that developed them, used them, and brought them to fruition * Provides the "builder's manual" for essential techniques--a one-stop shop that eliminates needless searching among untested techniques * Includes step-by-step methods for understanding the cell and molecular basis of wound healing, vascular integrin signaling, mechanical signaling in blood vessels, and vascular proteomics

Author : Gini Holland
Publisher : Gareth Stevens Publishing LLLP
Page : 28 pages
File Size : 49,5 Mb
Release : 2004-01-04
Category : Juvenile Nonfiction
ISBN : 083684131X

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I Live in a Town / Vivo en un pueblo by Gini Holland Pdf

A very simple and brief description of what it is like to live in a town.

Author : Nicolau Beckmann,Igor A. Kaltashov,Albert D. Windhorst
Publisher : Frontiers Media SA
Page : 224 pages
File Size : 41,9 Mb
Release : 2017-08-08
Category : Electronic book
ISBN : 9782889452378

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In Vivo Imaging in Pharmacological Research by Nicolau Beckmann,Igor A. Kaltashov,Albert D. Windhorst Pdf

The discovery and development of a biological active molecule with therapeutic properties is an ever increasing complex task, highly unpredictable at the early stages and marked, in the end, by high rates of failure. As a consequence, the overall process leading to the production of a successful drug is very costly. The improvement of the net outcome in drug discovery and development would require, amongst other important factors, a good understanding of the molecular events that characterize the disease or pathology in order to better identify likely targets of interest, to optimize the interaction of an active agent (small molecule or macromolecule of natural or synthetic origin) with those targets, and to facilitate the study of the pharmacokinetics, pharmacodynamics and toxicity of an active agent in suitable models and in human subjects. The objective of this Research Topic is to highlight new developments and applications of imaging techniques with the objective of performing pharmacological studies in vivo, in animal models and in humans. In the domain of drug discovery, the pharmacological and biomedical questions constitute the center of attention. In this sense, it is fundamental to keep in mind the strengths and limitations of each analytical or imaging technique. At the end, the judicious application of the technique with the aim of supporting the search for answers to manifold questions arising during a long and painstaking path provides a continuous role for imaging within the complex area of drug discovery and development.