Yearbook Of Cell And Tissue Transplantation 1996 1997

Author : R.P. Lanza,B.B. Chick
Publisher : Springer Science & Business Media
Page : 280 pages
File Size : 43,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400901650

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Yearbook of Cell and Tissue Transplantation 1996–1997 by R.P. Lanza,B.B. Chick Pdf

Cell and tissue transplantation is one of the most exciting and rapidly expanding areas in medicine. This first edition of the Yearbook of Cell and Tissue Transplantation summarizes the latest advances in this revolutionary field, including developments in tissue engineering and transplantation of hybrid organs and tissues, while reviewing those data which, while not new, add to the usefulness of this work as a comprehensive reference. The justification for yearbooks is greater than ever as we approach the third millennium, overwhelmed with information. In view of the important and rapid changes occurring in this area, a new edition of this yearbook will appear periodically. The editors' careers at Harvard Medical School guarantee the quality of this book. The authors, too, are uniformly drawn from the highest rank of an unusually dedicated and heterogeneous professional group. from the Foreword by Thomas E. Starzl, Honorary President, The Cell Transplant Society: `No major topic in the global field is left uncovered ... the result will be a feast for those already well informed, and a life raft for those who are not.'

Author : Robert Paul Lanza,William Louis Chick
Publisher : Unknown
Page : 128 pages
File Size : 44,8 Mb
Release : 1996
Category : Transplantation of organs, tissues, etc
ISBN : OCLC:1282039984

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Yearbook of Cell and Tissue Transplantation by Robert Paul Lanza,William Louis Chick Pdf

Author : David K.C. Cooper,Ejvind Kemp,Jeffrey L. Platt,David J.G. White
Publisher : Springer Science & Business Media
Page : 877 pages
File Size : 55,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642605727

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Xenotransplantation by David K.C. Cooper,Ejvind Kemp,Jeffrey L. Platt,David J.G. White Pdf

This is a time ofexcitement and progress in the field ofxenotransplantation. The work described in this book traces the development of the science of cross-spe cies transplantation, summarizes the current state ofour knowledge, and focuses on approaches directed toward future clinical application. The important question is not whether xenotransplantation will succeed, but rather how and under what circumstances xenografts will provide predictable enough results to warrant clinical application. The fact that the best results to date in clinical xenografting were achieved over three decades ago should not be a matter of discouragement, but rather a stimulus to apply new approaches to this area of work. The shortage of human organs for transplantation is cited frequently as the driving force behind the increased interest in xenotransplantation. This shortage is an undeniable fact, but there are additional potential advantages of xenotrans plantation, such as the ability to schedule replacement surgery on an elective basis and the modification of animals, organs, and tissues to improve acceptabil ity in the human host. The advances in the basic science ofxenotransplantation outlined in this book give hope that the immunologic barriers to xenotransplantation will be overcome and that transplanted organs and tissues will succeed consistently in humans. However, if our experience with human allografts provides an analogy, we may anticipate that clinical progress in xenografts will be plagued by failures and rewarded by successes, often without a complete understanding of the mechan isms involved.

Author : Thomas B. Freeman,Hakan Widner
Publisher : Springer Science & Business Media
Page : 361 pages
File Size : 44,9 Mb
Release : 1998-05-29
Category : Medical
ISBN : 9781592594764

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Cell Transplantation for Neurological Disorders by Thomas B. Freeman,Hakan Widner Pdf

Distinguished medical researchers from around the world review novel neural reconstructive techniques that appear to be beneficial for Parkinson's disease and hold promise for treating Huntington's disease, pain, demyelinating diseases, and stroke. The contributors focus on those diseases for which clinical trials are either ongoing or likely to occur in the near future. Among the topics reviewed are results and rationale for some of the leading transplant programs for the treatment of Parkinson's disease, the use of PET scanning for patient evaluation, autopsy studies of transplant recipients, transplant immunology, fetal tissue transplantation for Huntington's disease, cellular transplantation for the treatment of pain and stroke, and transplantation of myelinating cells. A full discussion of the important ethical issues surrounding the use of fetal tissue for transplantation purposes is also included.

Author : A. Keating,K. Dicke,N. Gorin,R. Weber,H. Graf
Publisher : Springer Science & Business Media
Page : 188 pages
File Size : 55,9 Mb
Release : 2007-01-19
Category : Medical
ISBN : 9783540268437

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Regenerative and Cell Therapy by A. Keating,K. Dicke,N. Gorin,R. Weber,H. Graf Pdf

This book gives an updated review of the state of the art in regenerative cell therapy in the fields of cardiology, hematology, pediatrics, neurology, orthopedics and infectious diseases. The book emphasizes clinical advances as proof of concept in cell therapy based on the revolutionizing observation that regeneration can occur throughout the body even in highly differentiated organs like the heart and the neuronal system. It provides examples of breakthroughs in the clinical implementation of adult stem cell therapy.

Author : Manfred R. Koller,Bernhard Palsson,John Masters
Publisher : Springer Science & Business Media
Page : 342 pages
File Size : 54,7 Mb
Release : 1999-07-31
Category : Medical
ISBN : 9780792358213

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Human Cell Culture by Manfred R. Koller,Bernhard Palsson,John Masters Pdf

Describes research technology for the growth and differentiation of all 12 types of the primary hematopoietic cells that develop into the various types of blood cells. Also provides background information, discusses current and future clinical applications of large-scale culture methods, and considers regulatory and ethical implications associated with using human and fetal tissues. The 13 studies include treatments of hematopoietic stem and progenitor cells, monocytes and macrophages, isolating and culturing human dendritic cells, purifying and culturing erythroid progenitor cells, the in vitro development of megakaryocytes and platelets, the mature polyclonal and antigen- specific cell expansion of T-lymphocytes, and in vitro T- lymphopoiesis. They are not indexed. Annotation copyrighted by Book News, Inc., Portland, OR

Author : Nima Rezaei
Publisher : Elsevier
Page : 420 pages
File Size : 44,6 Mb
Release : 2022-09-13
Category : Medical
ISBN : 9780323853903

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Translational Autoimmunity, Volume 5 by Nima Rezaei Pdf

Translational Autoimmunity: Challenges for Autoimmune Diseases, Fifth Edition addresses diagnostic approaches, therapeutic opportunities, and prognostic markers of different autoimmune diseases. This updated volume discusses autotoxicity, systems immunology, the prognostic significance of disease-specific autoantibodies, along with translational research to novel therapeutic policy in autoimmune diseases. From an introduction, to challenges and insights on the systems immunology of infectious and autoimmune diseases, new targets of treatments, and the role of autoantibodies in diagnosis and evolution, this book provides insights on many challenges researchers and clinicians are facing. Describes challenges in the diagnosis, management and treatment of autoimmune diseases Highlights major difficulties in the diagnosis and management of autoimmune diseases Reflects important remediable deficiencies in current management Meets the needs of basic scientists, clinicians and translational scientists and industry partners

Author : William J. Freed
Publisher : MIT Press
Page : 590 pages
File Size : 50,6 Mb
Release : 2000
Category : Central nervous system
ISBN : 0262062089

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Neural Transplantation by William J. Freed Pdf

After providing basic background on transplantation, brain structure, and development, the book discusses Parkinson's disease, the use of transplants to influence localized brain functions, circuit reconstruction, and genetic engineering and other future technologies.

Author : Holger Andreas Russ,Timo Otonkoski,Shuibing Chen
Publisher : Frontiers Media SA
Page : 173 pages
File Size : 52,6 Mb
Release : 2022-05-31
Category : Medical
ISBN : 9782889762835

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Advances in Stem Cell Technology to Model and Treat Diabetes by Holger Andreas Russ,Timo Otonkoski,Shuibing Chen Pdf

Author : Susan C. Brown,Jack A. Lucy
Publisher : Cambridge University Press
Page : 360 pages
File Size : 41,5 Mb
Release : 1997-05-13
Category : Medical
ISBN : 0521550335

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Dystrophin by Susan C. Brown,Jack A. Lucy Pdf

The absence of dystrophin is the underlying cause of Duchenne muscular dystrophy. This is the first book to address the structure, function, and distribution of dystrophin and its associated proteins in muscle and brain, rather than concentratiing primarily on the disease. It covers an exciting and rapidly expanding field that promises to have important and widespread implications for many aspects of cell biology.

Author : Insup Noh,Xiumei Wang,Sandra van Vlierberghe
Publisher : Royal Society of Chemistry
Page : 505 pages
File Size : 44,5 Mb
Release : 2021-07-30
Category : Technology & Engineering
ISBN : 9781788018838

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Injectable Hydrogels for 3D Bioprinting by Insup Noh,Xiumei Wang,Sandra van Vlierberghe Pdf

Hydrogels represent one of the cornerstones in tissue engineering and regenerative medicine, due to their biocompatibility and physiologically relevant properties. These inherent characteristics mean that they can be widely exploited as bioinks in 3D bioprinting for tissue engineering applications as well as injectable gels for cell therapy and drug delivery purposes. The research in these fields is booming and this book provides the reader with a terrific introduction to the burgeoning field of injectable hydrogel design, bioprinting and tissue engineering. Edited by three leaders in the field, users of this book will learn about different classes of hydrogels, properties and synthesis strategies to produce bioinks. A section devoted to the key processing and design challenges at the hydrogel/3D bioprinting/tissue interface is also covered. The final section of the book closes with pertinent clinical applications. Tightly edited, the reader will find this book to be a coherent resource to learn from. It will appeal to those working across biomaterials science, chemical and biomedical engineering, tissue engineering and regenerative medicine.

Author : David K. C. Cooper M.D.,Robert P. Lanza M.D.
Publisher : Oxford University Press
Page : 304 pages
File Size : 44,6 Mb
Release : 2000-03-23
Category : Medical
ISBN : 9780190284503

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Xeno: The Promise of Transplanting Animal Organs into Humans by David K. C. Cooper M.D.,Robert P. Lanza M.D. Pdf

The plight of a patient waiting months, sometimes years, for an organ transplant is one of the most heart-wrenching predicaments confronting medicine today. But the current critical shortage of human donor organs has had one positive consequence: it has stimulated promising new research into the field of xenotransplantation--the transplantation of organs from one animal species to another. In Xeno: The Promise of Transplanting Animal Organs Into Humans, David Cooper and Robert Lanza explore what may become one of the greatest medical advances of the 21st century. As scientists genetically engineer animal organs to evade the problems of rejection, we can expect a tremendous increase in xenotransplantation. This book recounts the several historical attempts to transplant animal organs into humans, and draws attention to the immense potential and promise of this form of therapy. The problems which remain, and recent breakthroughs in overcoming rejection and in "humanizing" pig organs for transplantation, are fully discussed. The authors also provide a fascinating consideration of the social and ethical questions posed by such procedures. Which patients should be the first to be offered this new form of therapy? Will transplanted animal organs transfer infectious viruses to the human recipient, and will they then be passed on to the community at large? Can society afford the major increase in healthcare expenditure that will result from our ability to provide a limitless number of donor organs? With profound implications for human health and longevity in the next millennium, Xeno is essential reading for anyone interested in the future of medicine.

Author : Bela Wrench,Anna Castleton,Michael Austin
Publisher : Karger Medical and Scientific Publishers
Page : 108 pages
File Size : 49,5 Mb
Release : 2022-06-30
Category : Medical
ISBN : 9783318069778

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Fast Facts: Acute Lymphoblastic Leukemia by Bela Wrench,Anna Castleton,Michael Austin Pdf

Acute lymphoblastic leukemia (ALL) is the most diagnosed childhood cancer worldwide. Although rare in adults, this aggressive cancer also shows a second smaller incidence peak in later middle age.

Modern genetic profiling techniques are providing a better understanding of the molecular biology of ALL, which, in turn, is leading to significant advances in diagnosis, prognostication and therapy selection. Ongoing refinement of risk-adapted frontline treatment protocols, use of novel targeted therapies and better supportive care are improving outcomes for patients with ALL.

Fast Facts: Acute Lymphoblastic Leukemia covers the epidemiology, etiology, diagnosis and classification of ALL as well as the measurement of minimal residual disease to determine prognosis. It provides guidance on frontline therapies and the treatment of relapsed and refractory ALL, including the use of newer targeted agents and the role of allogeneic stem-cell transplantation. Looking to the future, it also considers the approaches and refinements that are in development for ALL. Table of Contents:

Author : Robert Lanza,Robert Langer,Joseph P. Vacanti
Publisher : Elsevier
Page : 995 pages
File Size : 47,7 Mb
Release : 2000-05-16
Category : Science
ISBN : 9780080539676

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Principles of Tissue Engineering by Robert Lanza,Robert Langer,Joseph P. Vacanti Pdf

The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition of the book, published in 1997, is the definite reference in the field. Since that time, however, the discipline has grown tremendously, and few experts would have been able to predict the explosion in our knowledge of gene expression, cell growth and differentiation, the variety of stem cells, new polymers and materials that are now available, or even the successful introduction of the first tissue-engineered products into the marketplace. There was a need for a new edition, and this need has been met with a product that defines and captures the sense of excitement, understanding and anticipation that has followed from the evolution of this fascinating and important field. Key Features * Provides vast, detailed analysis of research on all of the major systems of the human body, e.g., skin, muscle, cardiovascular, hematopoietic, and nerves * Essential to anyone working in the field * Educates and directs both the novice and advanced researcher * Provides vast, detailed analysis of research with all of the major systems of the human body, e.g. skin, muscle, cardiovascular, hematopoietic, and nerves * Has new chapters written by leaders in the latest areas of research, such as fetal tissue engineering and the universal cell * Considered the definitive reference in the field * List of contributors reads like a "who's who" of tissue engineering, and includes Robert Langer, Joseph Vacanti, Charles Vacanti, Robert Nerem, A. Hari Reddi, Gail Naughton, George Whitesides, Doug Lauffenburger, and Eugene Bell, among others

Author : Luc J.W. Van der Laan,Bart Spee,Monique M. A. Verstegen
Publisher : MDPI
Page : 132 pages
File Size : 54,6 Mb
Release : 2019-11-19
Category : Science
ISBN : 9783039217441

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Bioengineering Liver Transplantation by Luc J.W. Van der Laan,Bart Spee,Monique M. A. Verstegen Pdf

The aim of this Special Issue is to review, understand, and evaluate new and exciting opportunities from the field on regenerative medicine, biomaterials, and stem cell research for the bioengineering of human liver grafts that can be applied for transplantation and personalized treatment of end-stage liver disease.The development of culture conditions for long-term expansion of LGR5+ intestinal stem cells as crypt-villus structures demonstrated the feasibility of deriving complex, organ-like structures in vitro from primary adult tissues, including the liver. Moreover, human pluripotent stem cells (hPSCs) can be applied to generate functionally maturated liver and bile duct epithelial cells.In this Special Issue, we welcome reviews and original papers focussing on hepatic cell sources, including adult hepatic stem cells, organoids, fetal and induced pluripotent stem cells, and primary cells (i.e., hepatocytes, cholangiocytes, and endothelial cells) and how these cells can be applied in tissue engineering strategies to generate implantable and personalized liver grafts. Potential topics include, but are not limited to, the following: liver tissue engineering, liver regeneration, graft repair, liver stem cells and organoids, bio-scaffolds, and 3D printing.We invite you to contribute original research papers, as well as comprehensive reviews, aligned with these themes, to advance and improve the actual state-of-the-art in liver bioengineering and providing new opportunities for the imminent medical problem of organ and tissue shortage for transplantation.