Advanced Free Radical Reactions For Organic Synthesis

Author : Hideo Togo
Publisher : Elsevier
Page : 270 pages
File Size : 47,5 Mb
Release : 2004-01-14
Category : Science
ISBN : 0080524257

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Advanced Free Radical Reactions for Organic Synthesis by Hideo Togo Pdf

Free radical reactions have become increasingly important and a very attractive tool in organic synthesis in the last two decades, due to their powerful, selective, specific, and mild reaction abilities. Advanced Free Radical Reactions for Organic Synthesis reviews information on all types of practical radical reactions, e.g. cyclizations, additions, hydrogen-atom abstractions, decarboxylation reactions. The book usefully provides experimental details for the most important reactions as well as numerous references to the original literature. By covering both the fundamentals and synthetic applications it is therefore suitable for both new and experienced researchers, chemists, biochemists, natural product chemists and graduate students. This title is the definitive guide to radical chemistry for all scientists. Introduces and reviews the use of radicals to perform synthetic transformations Practical details are provided for the most important methods Numerous references to the original literature

Author : Samir Z. Zard
Publisher : Oxford Chemistry Masters
Page : 280 pages
File Size : 46,5 Mb
Release : 2003
Category : Science
ISBN : 0198502419

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Radical Reactions in Organic Synthesis by Samir Z. Zard Pdf

Samir Zard provides a description of radical reactions and their applications in organic synthesis. This book shows that an with an elementary knowledge of kinetic and some common sense, it is possible to harness radicals into a tremendously powerful tool for solving synthetic problems.

Author : D. I. Davies,M. J. Parrott
Publisher : Springer Science & Business Media
Page : 181 pages
File Size : 45,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642669224

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Free Radicals in Organic Synthesis by D. I. Davies,M. J. Parrott Pdf

Author : William B. Motherwell,David Crich
Publisher : Elsevier
Page : 288 pages
File Size : 51,9 Mb
Release : 2013-10-22
Category : Science
ISBN : 9780080924953

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Free Radical Chain Reactions in Organic Synthesis by William B. Motherwell,David Crich Pdf

Written for both the experienced practitioner and the newcomer, this book provides essential guidance to the practical aspects of free radical chain reactions. The book presents tried and tested synthetic schemes as well as a selection of recently developed methods describing rationally designed, highly efficient syntheses giving high yield interconversions of functional groups and carbon*b1carbon bond formation under mild, neutral conditions. Written by two experienced practitioners in the field, this volume explodes the myth that free radicals are highly reactive, non-selective intermediates. Contains an extensive introduction discussing principles, advantages, and disadvantages of radical chain reactions Demonstrates functional group interconversions by radical chain reactions Lists carbon*b1carbon bond formations Presents inter- and intramolecular radical chain reactions Includes many examples and experimental details selected by experienced practitioners in this field

Author : Bernd Giese
Publisher : C R C Press Reprints
Page : 318 pages
File Size : 41,5 Mb
Release : 1986
Category : Science
ISBN : UOM:39015016094107

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Radicals in Organic Synthesis by Bernd Giese Pdf

Author : V. Tamara Perchyonok
Publisher : Royal Society of Chemistry
Page : 142 pages
File Size : 47,7 Mb
Release : 2010
Category : Science
ISBN : 9781849730006

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Radical Reactions in Aqueous Media by V. Tamara Perchyonok Pdf

Radical Reactions in Aqueous Media provides a step-wise introduction, taking students from the basic principles of radical reactions through to their applications in industry and their role in biological and environmental processes."--Jacket.

Author : Andrew F. Parsons
Publisher : Wiley-Blackwell
Page : 252 pages
File Size : 44,6 Mb
Release : 2000-11-30
Category : Science
ISBN : 0632052929

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An Introduction to Free Radical Chemistry by Andrew F. Parsons Pdf

The past twenty years has seen an explosion of interest in free radicals, as their pivotal role in both chemistry and biology has come to light. This introductory textbook aims to capture this excitement for advanced level undergraduates, with particular emphasis on the importance of radical reactions in organic synthesis. The book provides a gentle, stepwise introduction to the subject, taking the student from the basic principles of radical reactions through to their applications in industry and their role in biological and environmental processes, allowing the relevance of the subject to be grasped more easily. Suitable for advanced level undergraduates and postgraduates in chemistry and biochemistry, the book will also be invaluable for research level scientists requiring an update in the area.

Author : Jacques Fossey,Daniel Lefort,Janine Sorba
Publisher : Unknown
Page : 328 pages
File Size : 49,8 Mb
Release : 1995-11-09
Category : Business & Economics
ISBN : MINN:31951D01198561E

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Free Radicals in Organic Chemistry by Jacques Fossey,Daniel Lefort,Janine Sorba Pdf

Free radicals constitute the most frequently used class of reaction intermediates in organic chemistry. This study describes the structure and reactivity of free radicals, and explores their role in both natural phenomena and in the design of new reaction pathways.

Author : Derek H. R. Barton,Sir Derek Barton,Shyamal I. Parekh
Publisher : Cambridge University Press
Page : 180 pages
File Size : 52,5 Mb
Release : 1993-04-15
Category : Science
ISBN : 0521445809

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Half a Century of Free Radical Chemistry by Derek H. R. Barton,Sir Derek Barton,Shyamal I. Parekh Pdf

This book describes the experience over 25 years of the senior author with the chemistry of organic free radicals. It begins with a mechanistic study of industrial importance on the pyrolysis of chlorinated alkanes. It continues with a theory on the biosynthesis of phenolate derived alkaloids involving phenolate radical coupling. There follows 20 years of practical work to prove the theory correct, especially in the case of morphine alkaloids. The book then describes the work on nitrile photolysis (Barton reaction) which involved the invention of new radical chemistry leading to a simple synthesis of the important hormone, aldosterone. There follows a description of the invention of an important new method for the deoxygenation of biologically important molecules, especially sugars and nucleosides, using radical chemistry applied to thiocarbonyl derivatives. Some years later, in a logical extension to carboxylic acids, another new reaction was invented which provides carbon, nitrogen, oxygen and other radicals under mild conditions. A final chapter summarizes recent applications of thiocarbonyl group derived radical reactions by other authors.

Author : F. Minisci
Publisher : Springer Science & Business Media
Page : 487 pages
File Size : 48,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400908970

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Free Radicals in Synthesis and Biology by F. Minisci Pdf

Free-radical reactions have been for long time the domain of the physical chemists and the basic chemical industry (polymerization of vinyl monomers, oxidation by molecular oxygen, chlorination of methane etc.), where the use of simple molecules and the possibility of partial conversions without heavy problems of product separations makes less dramatic the aspects of regio and chemoselectivity. As synonym of unselectivity, free radical reactions were considered of poor use in the synthesis of fine chemicals or sophisticated molecules, where a high selectivity is an essential condition for the success, or in the involvement of biological processes. Within the last 15 years, however, an authentic explosion of synthetic applications of free radical reactions occurred; they have gained a remarkable position among the selective methods of synthesis. At the same time the great importance of free radical reactions in fundamental biological processes and in the metabolism of drugs has been recognized. Thus a specialized meeting on these topics was generally felt appropriate. I had the honour and the onus to organize this workshop because for more than 30 years I have been involved in the research of free radical reactions. Thanks to a generous grant from NATO Scientific Affairs Division and the financial support of CNR and chemical industry (Montedison, Enichem, Zambon) such a meeting among almost 50 specialists and 15 observers of sufficient standard to take advantage of the discussion, became possible at Bardolino (Italy).

Author : L. Fensterbank,C. Ollivier
Publisher : Thieme
Page : 774 pages
File Size : 43,5 Mb
Release : 2021-07-09
Category : Science
ISBN : 9783132442160

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Science of Synthesis: Free Radicals: Fundamentals and Applications in Organic Synthesis 1 by L. Fensterbank,C. Ollivier Pdf

Radically enhance your progress in organic synthesis Radical chemistry has undergone a renaissance in recent years. These two volumes will make the key developments accessible to a broad range of organic chemists. They cover both the generation of radicals and their use. The editors, Prof. Louis Fensterbank and Dr. Cyril Ollivier, are experts in radical chemistry and its application to organic synthesis. Find out all about the generation and use of radicals The two-volume set describes the fundamentals of radical chemistry and its application in organic synthesis. It includes practical examples of the generation of a variety of organic radicals. You will find critically reviewed, reliable and ready-to-use information on the use of radicals in: "single-electron transfer" "hydrogen-atom transfer" radical functionalization and cross-coupling processes. By understanding the fundamental reactivities of radicals, they can be harnessed for atom-efficient and green reactions.

Author : L. Fensterbank,C. Ollivier
Publisher : Thieme
Page : 708 pages
File Size : 50,8 Mb
Release : 2020-12-17
Category : Science
ISBN : 9783132442177

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Science of Synthesis: Free Radicals: Fundamentals and Applications in Organic Synthesis 2 by L. Fensterbank,C. Ollivier Pdf

Radically enhance your progress in organic synthesis Radical chemistry has undergone a renaissance in recent years. These two volumes will make the key developments accessible to a broad range of organic chemists. They cover both the generation of radicals and their use. The editors, Prof. Louis Fensterbank and Dr. Cyril Ollivier, are experts in radical chemistry and its application to organic synthesis. Find out all about the generation and use of radicals The two-volume set describes the fundamentals of radical chemistry and its application in organic synthesis. It includes practical examples of the generation of a variety of organic radicals. You will find critically reviewed, reliable and ready-to-use information on the use of radicals in: "single-electron transfer" "hydrogen-atom transfer" radical functionalization and cross-coupling processes. By understanding the fundamental reactivities of radicals, they can be harnessed for atom-efficient and green reactions.

Author : Philippe Renaud (Prof),Mukund P. Sibi
Publisher : Unknown
Page : 632 pages
File Size : 55,9 Mb
Release : 2001
Category : Chemical reactions
ISBN : UVA:X004523481

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Radicals in Organic Synthesis by Philippe Renaud (Prof),Mukund P. Sibi Pdf

Author : Francis A. Carey,Richard J. Sundberg
Publisher : Springer Science & Business Media
Page : 829 pages
File Size : 47,8 Mb
Release : 2013-11-11
Category : Science
ISBN : 9781461397953

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Advanced Organic Chemistry by Francis A. Carey,Richard J. Sundberg Pdf

The purpose of this edition, like that of the earlier ones, is to provide the basis for a deeper understanding of the structures of organic compounds and the mechanisms of organic reactions. The level is aimed at advanced undergraduates and beginning graduate students. Our goals are to solidify the student's understanding of basic concepts provided by an introduction to organic chemistry and to present more information and detail, including quantitative information, than can be presented in the first course in organic chemistry. The first three chapters consider the fundamental topi~s of bonding theory, stereochemistry, and conformation. Chapter 4 discusses the techniques that are used to study and characterize reaction mechanisms. Chapter 9 focuses on aromaticity and the structural basis of aromatic stabilization. The remaining chapters consider basic reaction types, including substituent effects and stereochemistry. As compared to the earlier editions, there has been a modest degree of reorganization. The emergence of free-radical reactions in synthesis has led to the inclusion of certain aspects of free-radical chemistry in Part B. The revised chapter, Chapter 12, empha sizes the distinctive mechanistic and kinetic aspects of free-radical reactions. The synthetic applications will be considered in Part B. We have also split the topics of aromaticity and the reactions of aromatic compounds into two separate chapters, Chapters 9 and 10. This may facilitate use of Chapter 9, which deals with the nature of aromaticity, at an earlier stage if an instructor so desires.

Author : Dennis P. Curran,Ned A. Porter,Bernd Giese
Publisher : John Wiley & Sons
Page : 294 pages
File Size : 40,9 Mb
Release : 2008-09-26
Category : Science
ISBN : 9783527615223

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Stereochemistry of Radical Reactions by Dennis P. Curran,Ned A. Porter,Bernd Giese Pdf

As little as a decade ago, radicals were regarded as interesting reactive intermediates with little synthetic use. However, recent results show that radicals have an enormous potential for applications in stereoselective reactions - it's all a matter of knowing what method to use and how to apply it. Three world experts in the field have combined their expertise and present the concepts to understand and even to predict the course of stereoselective radical reactions. In addition, guidelines are established which will enable the readers to plan and carry out their own stereoselective syntheses with radicals. A comprehensive list of references provides an easy access to the primary literature. The Stereochemistry of Radical Reactions is a highly topical introduction to this burgeoning field of research. Both advanced students and researchers active in the field will welcome this book as a source of concepts and ideas.