An Introduction To Free Radical Chemistry

Author : Andrew F. Parsons
Publisher : Wiley-Blackwell
Page : 252 pages
File Size : 52,8 Mb
Release : 2000-11-30
Category : Science
ISBN : 0632052929

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An Introduction to Free Radical Chemistry by Andrew F. Parsons Pdf

The past twenty years has seen an explosion of interest in free radicals, as their pivotal role in both chemistry and biology has come to light. This introductory textbook aims to capture this excitement for advanced level undergraduates, with particular emphasis on the importance of radical reactions in organic synthesis. The book provides a gentle, stepwise introduction to the subject, taking the student from the basic principles of radical reactions through to their applications in industry and their role in biological and environmental processes, allowing the relevance of the subject to be grasped more easily. Suitable for advanced level undergraduates and postgraduates in chemistry and biochemistry, the book will also be invaluable for research level scientists requiring an update in the area.

Author : Jacques Fossey,Daniel Lefort,Janine Sorba
Publisher : Unknown
Page : 328 pages
File Size : 42,6 Mb
Release : 1995-11-09
Category : Business & Economics
ISBN : MINN:31951D01198561E

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Free Radicals in Organic Chemistry by Jacques Fossey,Daniel Lefort,Janine Sorba Pdf

Free radicals constitute the most frequently used class of reaction intermediates in organic chemistry. This study describes the structure and reactivity of free radicals, and explores their role in both natural phenomena and in the design of new reaction pathways.

Author : D. C. Nonhebel,J. C. Walton
Publisher : CUP Archive
Page : 620 pages
File Size : 42,5 Mb
Release : 1974-01-31
Category : Science
ISBN : 0521201497

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Free-Radical Chemistry by D. C. Nonhebel,J. C. Walton Pdf

Author : Rayson L. Huang,S. H. Goh,Soon Hock Augustine Ong
Publisher : Hodder Education
Page : 264 pages
File Size : 48,8 Mb
Release : 1974
Category : Carbonium ions
ISBN : UCAL:B5110188

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The Chemistry of Free Radicals by Rayson L. Huang,S. H. Goh,Soon Hock Augustine Ong Pdf

Author : Derek H. R. Barton,Sir Derek Barton,Shyamal I. Parekh
Publisher : Cambridge University Press
Page : 180 pages
File Size : 50,9 Mb
Release : 1993-04-15
Category : Science
ISBN : 0521445809

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Half a Century of Free Radical Chemistry by Derek H. R. Barton,Sir Derek Barton,Shyamal I. Parekh Pdf

This book describes the experience over 25 years of the senior author with the chemistry of organic free radicals. It begins with a mechanistic study of industrial importance on the pyrolysis of chlorinated alkanes. It continues with a theory on the biosynthesis of phenolate derived alkaloids involving phenolate radical coupling. There follows 20 years of practical work to prove the theory correct, especially in the case of morphine alkaloids. The book then describes the work on nitrile photolysis (Barton reaction) which involved the invention of new radical chemistry leading to a simple synthesis of the important hormone, aldosterone. There follows a description of the invention of an important new method for the deoxygenation of biologically important molecules, especially sugars and nucleosides, using radical chemistry applied to thiocarbonyl derivatives. Some years later, in a logical extension to carboxylic acids, another new reaction was invented which provides carbon, nitrogen, oxygen and other radicals under mild conditions. A final chapter summarizes recent applications of thiocarbonyl group derived radical reactions by other authors.

Author : Malcolm D. Forbes
Publisher : John Wiley & Sons
Page : 300 pages
File Size : 40,8 Mb
Release : 2010-01-22
Category : Science
ISBN : 0470584106

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Carbon-Centered Free Radicals and Radical Cations by Malcolm D. Forbes Pdf

Covers the most advanced computational and experimental methods for studying carbon-centered radical intermediates With its focus on the chemistry of carbon-centered radicals and radical cations, this book helps readers fully exploit the synthetic utility of these intermediates in order to prepare fine chemicals and pharmaceutical products. Moreover, it helps readers better understand their role in complex atmospheric reactions and biological systems. Thoroughly up to date, the book highlights the most advanced computational and experimental methods available for studying and using these critically important intermediates. Carbon-Centered Free Radicals and Radical Cations begins with a short history of the field of free radical chemistry, and then covers: A discussion of the relevant theory Mechanistic chemistry, with an emphasis on synthetic utility Molecular structure and mechanism, focusing on computational methods Spectroscopic investigations of radical structure and kinetics, including demonstrations of spin chemistry techniques such as CIDNP and magnetic field effects Free radical chemistry in macromolecules Each chapter, written by one or more leading experts, explains difficult concepts clearly and concisely, with references to facilitate further investigation of individual topics. The authors were selected in order to provide insight into a broad range of topics, including small molecule synthesis, polymer degradation, computational chemistry as well as highly detailed experimental work in the solid, liquid, and gaseous states. This volume is essential for students or researchers interested in building their understanding of the role of carbon-centered radical intermediates in complex systems and how they may be used to develop a broad range of useful products.

Author : William Pryor
Publisher : Elsevier
Page : 400 pages
File Size : 46,9 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323152211

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Frontiers of Free Radical Chemistry by William Pryor Pdf

Frontiers of Free Radical Chemistry covers the proceedings of the 1979 symposium on Frontiers of Free Radical Chemistry, held in Louisiana State University Chemistry Department, supported by the Exxon Education Foundation. The contributors discuss the mechanisms of hydrocarbon cracking; oxidation processes; inhibition; and the theory of organic radical reactions, halogenations, and organic peroxide chemistry. This book is organized into three parts encompassing 15 chapters. Part I deals with the understanding of molecular and free radical mechanisms in predicting thermochemical data for radicals and molecules. This part also describes the relationship between distortions of organic molecules and the reactions of pericyclic, ionic, and radical molecules. Part II presents quantitative evaluations of gas phase reactions or carbynes and hydrocarbon pyrolysis and cracking. Discussions on the reactions of free atoms and radicals in the chemistry of the stratosphere and natural troposphere, with an emphasis on the ozone layer and its potential depletion by artificial pollutants, are included in this part. Part III explores the pertinent free radical reactions related to fuel research. Petroleum chemists, researchers, and engineers will find this book invaluable.

Author : Gerhard Herzberg
Publisher : Courier Corporation
Page : 242 pages
File Size : 53,9 Mb
Release : 1988-01-01
Category : Technology & Engineering
ISBN : 9780486658216

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The Spectra and Structures of Simple Free Radicals by Gerhard Herzberg Pdf

"Authoritative and clearly written."—Applied Optics The direct observation of short-lived free radicals and the consequent study of their structure and reactions have led to important developments in almost every branch of chemistry as well as in other areas. This volume by a Nobel laureate offers an excellent introduction to the essentials of molecular spectroscopy. The introductory chapter discusses experimental methods and illustrates the observed spectra of various molecules and free radicals. Subsequent chapters explore rotational, vibrational, and electronic energy levels of diatomic molecules and ions; radiative transitions; linear and nonlinear polyatomic radicals and ions; continuous and diffuse spectra; predissociation and pre-ionization; and recombination. The well-illustrated text features more than 100 figures and spectra. A distilled version of the author's monumental three-volume study, Molecular Spectra and Molecular Structure, it constitutes a superb resource for anyone wishing a concise but complete treatment of the fundamentals of molecular spectroscopy.

Author : Toshikazu Yoshikawa
Publisher : Unknown
Page : 560 pages
File Size : 45,7 Mb
Release : 2000
Category : Antioxidants
ISBN : STANFORD:36105025027470

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Free Radicals in Chemistry, Biology and Medicine by Toshikazu Yoshikawa Pdf

Author : William A. Pryor
Publisher : Unknown
Page : 132 pages
File Size : 46,9 Mb
Release : 1966
Category : Chemistry, Organic
ISBN : UOM:39015065705363

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Introduction to Free Radical Chemistry by William A. Pryor Pdf

Author : Hideo Togo
Publisher : Elsevier
Page : 270 pages
File Size : 49,7 Mb
Release : 2004-01-14
Category : Science
ISBN : 0080524257

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Advanced Free Radical Reactions for Organic Synthesis by Hideo Togo Pdf

Free radical reactions have become increasingly important and a very attractive tool in organic synthesis in the last two decades, due to their powerful, selective, specific, and mild reaction abilities. Advanced Free Radical Reactions for Organic Synthesis reviews information on all types of practical radical reactions, e.g. cyclizations, additions, hydrogen-atom abstractions, decarboxylation reactions. The book usefully provides experimental details for the most important reactions as well as numerous references to the original literature. By covering both the fundamentals and synthetic applications it is therefore suitable for both new and experienced researchers, chemists, biochemists, natural product chemists and graduate students. This title is the definitive guide to radical chemistry for all scientists. Introduces and reviews the use of radicals to perform synthetic transformations Practical details are provided for the most important methods Numerous references to the original literature

Author : A.T. Diplock,M.C.R. Symons,C.A. Rice-Evans
Publisher : Elsevier
Page : 290 pages
File Size : 45,6 Mb
Release : 1991-12-11
Category : Science
ISBN : 0080858910

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Techniques in Free Radical Research by A.T. Diplock,M.C.R. Symons,C.A. Rice-Evans Pdf

Free radical species are generally short-lived due to their high reactivity and thus direct measurement and identification are often impossible. ESR is the only technique which has the potential for direct detection of radicals but in biological systems even these must be trapped by a spin-trapping agent. Thus most investigations involve recognition of indicators of the presence of radicals in vivo or "FOOTPRINTS" of radical-mediated damage. Techniques in Free Radical Research assembles and critically assesses the most relevant and reliable experimental approaches used towards the measurement of radicals and radical-mediated damage in chemical systems, in cells and in tissues under the following six headings: a) Footprints of DNA damage, b) Footprints of protein damage, c) Footprints of lipid peroxidation, d) Footprints of antioxidant consumption, e) Footprints via indirect radical assays, and f) Footprints via the availability of transition metal complexes.

Author : Emil Roduner
Publisher : Springer Science & Business Media
Page : 113 pages
File Size : 41,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642517204

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The Positive Muon as a Probe in Free Radical Chemistry by Emil Roduner Pdf

The work presented here is a result of an extended collaboration with a number of coworkers and guests. Particularly, I would like to thank Dr. P. Burkhard and Dr. W. Strub for their careful work performed for their Ph. D. thesis and Dr. M. Heming for his brilliant ideas and his dedication. Very fruitful and stimulating were collaborations with our guests, i. e. with G. A. Brinkman and P. W. F. Louwrier from NIKHEF-K in Amsterdam, B. C. Webster, M. J. Ramos and D. McKenna from the University of Glasgow, M. C. R. Symons, D. Geeson and C. J. Rhodes from the University of Leicester, S. F. J. Cox and C. A. Scott from the Rutherford Appleton Laboratory in Chilton, and R. De Renzi and M. Ricco from the University of Parma. Many invaluable discussions with friends and competitors in the field helped to address new viewpoints and to define new goals. I shall not forget my teacher and director of the radical chemistry group, Prof. H. Fischer, whom I wish to thank for his interest and active support and for the great liberty he allowed me for the planning and organization of the project. Last but not least, I thank my dear wife Hanny and our children Christian, Martin and Andrea who suffered, without complaint, daddy's absence for so many hours.

Author : Clemens Sonntag
Publisher : Springer Science & Business Media
Page : 528 pages
File Size : 49,5 Mb
Release : 2006-03-20
Category : Science
ISBN : 9783540305927

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Free-Radical-Induced DNA Damage and Its Repair by Clemens Sonntag Pdf

The free-radical chemistry of DNA had been discussed in some detail in 1987 in my book The Chemical Basis of Radiation Biology. Obviously, the more recent developments and the concomitant higher level of understanding of mechanistic details are missing. Moreover, in the living cell, free-radical DNA damage is not only induced by ionizing radiation, but free-radical-induced DNA damage is a much more general phenomenon. It was, therefore, felt that it is now timely to review our present knowledge of free-radical-induced DNA damage induced by all conceivable free-radical-generating sources. Originally, it had been thought to include also a very important aspect, the repair of DNA damage by the cell’s various repair enzymes. Kevin Prise (Cancer Campaign, Gray Laboratory, L- don) was so kind to agree to write this part. However, an adequate description of this strongly expanding area would have exceeded the allocated space by much, and this section had to be omitted. The directors of the Max-Planck-Institut für Strahlenchemie (now MPI für Bioanorganische Chemie), Karl Wieghardt and Wolfgang Lubitz, kindly allowed me to continue to use its facilities after my retirement in 2001. Notably, our - brarian, Mrs. Jutta Theurich, and her right-hand help, Mrs. Rosemarie Schr- er, were most helpful in getting hold of the literature. I thank them very much. Without their constant help, this would have been very difficult indeed.

Author : Cheves Walling
Publisher : Unknown
Page : 654 pages
File Size : 50,9 Mb
Release : 1957
Category : Science
ISBN : UCAL:B3850455

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Free Radicals in Solution by Cheves Walling Pdf