Anti Angiogenesis Strategies In Cancer Therapies

Anti Angiogenesis Strategies In Cancer Therapies Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Anti Angiogenesis Strategies In Cancer Therapies book. This book definitely worth reading, it is an incredibly well-written.

Anti-Angiogenesis Strategies in Cancer Therapies

Shaker Mousa,Paul Davis
Anti Angiogenesis Strategies in Cancer Therapies Book PDF

Author : Shaker Mousa,Paul Davis
Publisher : Academic Press
Page : 210 pages
File Size : 47,9 Mb
Release : 2016-11-28
Category : Medical
ISBN : 9780128026731

Get Book

Anti-Angiogenesis Strategies in Cancer Therapies by Shaker Mousa,Paul Davis Pdf

Anti-angiogenesis Strategies in Cancer Therapeutics provides a detailed look at the current status and future directions in the discovery and development of novel anti-angiogenesis strategies in oncology. This book highlights the different mechanisms involved in the modulation of angiogenesis, including inflammation, thrombosis, and microRNA, and shows how nanotechnology can further enhance the potential of existing and new anti-angiogenesis approaches. Written for industry scientists, researchers, oncologists, hematologists, and professors and students in the field, this comprehensive book covers all aspects of anti-angiogenesis strategies and their differences. Covers important preclinical models and clinical trials in the discovery and development of novel anti-angiogenesis agents Reviews FDA-approved anti-angiogenesis agents Illustrates the value of nanotechnology in improving the utility of anti-angiogenesis agents Offers insight into the development of novel anti-angiogenesis agents and future direction in this area

Antiangiogenic Cancer Therapy

Darren W. Davis,Roy S. Herbst,James L. Abbruzzese
Antiangiogenic Cancer Therapy Book PDF

Author : Darren W. Davis,Roy S. Herbst,James L. Abbruzzese
Publisher : CRC Press
Page : 864 pages
File Size : 49,5 Mb
Release : 2007-07-25
Category : Science
ISBN : 1420004298

Get Book

Antiangiogenic Cancer Therapy by Darren W. Davis,Roy S. Herbst,James L. Abbruzzese Pdf

Top Investigators Explore the Complexities of Angiogenesis Cancer Research The targeting of tumor angiogenesis has evolved into one of the most widely pursued therapeutic strategies. However, as of yet, no antiangiogenic agent used as a monotherapy has demonstrated a survival benefit in a randomized Phase III trial. The combination of bevacizumab, the first FDA approved angiogenesis inhibitor, with cytotoxic regimens has led to survival benefits in cancer patients. This has raised important questions about the complexities inherent in the clinical application of angiogenesis inhibitors. Compiles the results of four decades of progress Integrating fundamental concepts with therapeutic strategies, Anti-Angiogenic Cancer Therapy promotes the idea that an understanding of the molecular and cellular regulation of angiogenesis leads to optimal therapeutic strategies and positive clinical results. It brings together contributions from leading researchers to provide the most authoritative and encyclopedic volume available on this subject. Examines the role of angiogenesis in cancer, including strategies to prolong the nonangiogenic dormant state of human tumors, molecular mechanisms and cellular regulation of angiogenesis in solid tumors and hematologic malignancies, and the regulation of angiogenesis by the tumor microenvironment. Covers specific molecular targets for inhibiting angiogenesis in cancer therapy. Discusses clinical trial design and translational research approaches essential for identifying and developing effective angiogenesis inhibitors. Outlines current understanding of the molecular biology of each cancer type followed by discussions that examine strategies for targeting angiogenesis in specific cancers. This volume celebrates progress made in four decades, and more importantly, it provides a clear indication of the complex biology that needs further investigation to realize the possibilities envisioned for this beneficial therapeutic modality.

Adjuvant Therapy of Primary Breast Cancer VI

Hans-Jörg Senn,Richard D. Gelber,Aron Goldhirsch,Beat Thürlimann
Adjuvant Therapy of Primary Breast Cancer VI Book PDF

Author : Hans-Jörg Senn,Richard D. Gelber,Aron Goldhirsch,Beat Thürlimann
Publisher : Springer Science & Business Media
Page : 505 pages
File Size : 43,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642457692

Get Book

Adjuvant Therapy of Primary Breast Cancer VI by Hans-Jörg Senn,Richard D. Gelber,Aron Goldhirsch,Beat Thürlimann Pdf

This RRCR-conference-volume marks "number six" in a 20-year evolution of international conferences on the adjuvant therapy of primary breast cancer. Starting in 1978, a handful of some 80 en thusiastic breast cancer surgeons and oncologists, met in a se cluded mountain resort near st. Gallen in Eastern Switzerland, to exchange their early data of some pioneer trials on adjuvant sys temic therapy of early breast cancer, and to correlate their future research efforts to overcome the frustrating prognostic stagna tion of this dominant neoplastic disease in Western females dur ing the past decades. Repeated every 3-4 years, these St. Gallen International Conferences on Adjuvant Therapy of Primary Breast Cancer have continuously grown in numbers of partici pants and in normative, therapeutic influence by being published in major oncology journals [1-3], the last (6th) conference hav ing taken place from February 25-28, 1998 with more than 1800 attendees from over 50 countries worldwide. What is the fascination of adjuvant therapy in primary (early) breast cancer, and what has changed,during the last 3 years since March 1995, to justify another international gathering of this size, and of the world's leading experts in the field? There is no question, that providing even more effective care and designing appropriate recommendations for the multitudes of patients with so-called early breast cancer or at high risk of developing the disease, remain highly important public health goals.

Tumor Angiogenesis

Dieter Marmé,Norbert Fusenig
Tumor Angiogenesis Book PDF

Author : Dieter Marmé,Norbert Fusenig
Publisher : Springer Science & Business Media
Page : 845 pages
File Size : 51,9 Mb
Release : 2007-12-05
Category : Medical
ISBN : 9783540331773

Get Book

Tumor Angiogenesis by Dieter Marmé,Norbert Fusenig Pdf

Tumor angiogenesis is one of the most prominent mechanisms driving tumor development and progression. This book is written by internationally renowned experts. Part 1 describes the basic mechanisms. Tumor-angiogenic signaling pathways are presented as new potential targets for anti-angiogenic therapy. Part 2 reviews the efforts made to validate new targets and to show efficacy in animals. Part 3 is devoted to the clinical development of the novel anti-angiogenic drugs and their use in clinical practice.

Nanoparticles in Angiogenesis and Cancer

Sudip Mukherjee,Vijay Sagar Madamsetty
Nanoparticles in Angiogenesis and Cancer Book PDF

Author : Sudip Mukherjee,Vijay Sagar Madamsetty
Publisher : Springer Nature
Page : 85 pages
File Size : 40,8 Mb
Release : 2022-09-27
Category : Technology & Engineering
ISBN : 9783031112843

Get Book

Nanoparticles in Angiogenesis and Cancer by Sudip Mukherjee,Vijay Sagar Madamsetty Pdf

This book highlights recent developments of organic and inorganic nanomedicine that play a major role in anti-angiogenic cancer therapy. In addition, the authors present examples of nanomedicine based anti-angiogenic agents and their applications in cancer therapy. Angiogenesis is a pathophysiological phenomenon that modulates cell proliferation and cell migration and plays important roles in cancer. Anti-angiogenic nanotherapies have gained immense attention in recent times as alternative cost-effective therapies that opened a new dimension in cancer theranostics. Further the challenges of the anti-angiogenic nanotherapies and possible future perspective are detailed.

Antiangiogenic Drugs as Chemosensitizers in Cancer Therapy

Anonim
Antiangiogenic Drugs as Chemosensitizers in Cancer Therapy Book PDF

Author : Anonim
Publisher : Academic Press
Page : 296 pages
File Size : 43,6 Mb
Release : 2022-01-14
Category : Science
ISBN : 9780323905565

Get Book

Antiangiogenic Drugs as Chemosensitizers in Cancer Therapy by Anonim Pdf

Anti-angiogenic Drugs as Chemosensitizers in Cancer Therapy, Volume 19 focuses on the use of anti-angiogenic drugs as sensitizers of tumor cells to the inhibitory activity of antitumor agents. Conventional and novel anti-neoplastic agents (cytotoxic molecules, hormones/antihormones, immunotherapies) are taken into consideration, along with advances made in combination therapies. The book encompasses examples of studies on the use of antiangiogenic compounds—molecules that inhibit the growth of vessels inside a tumor—together with antineoplastic drugs in order to sensitize the resistant tumor to their cytotoxic effects, thus reducing adverse side reactions and resistance and improving the therapeutic response of cancer patients. In addition, the book discusses clinical applications in various types of cancer, such as colorectal, lung, breast, renal, genitourinary, skin and brain and circulating tumors. It is a valuable resource for cancer researchers, clinicians and members of the biomedical field who wants to be up-to-date on the most recent and promising developments in the field. Provides the most updated reviews on anti-angiogenic drugs as chemosensitizers by leaders in the field Encompasses summarized tables and schematic diagrams in each chapter to give a clear overview on recent findings in a didactic manner Brings not only relevant information of current research but also new ideas and suggestions for further investigations to help advance the field

Tumor Angiogenesis

Dieter Marmé
Tumor Angiogenesis Book PDF

Author : Dieter Marmé
Publisher : Springer
Page : 0 pages
File Size : 48,5 Mb
Release : 2019-10-18
Category : Medical
ISBN : 3319336711

Get Book

Tumor Angiogenesis by Dieter Marmé Pdf

This exhaustive work shows that new therapies using anti-angiogenic drugs are of particular importance because they can be used against many different types of cancer, as tumor angiogenesis seems to be involved in most if not all solid metastasizing malignancies. The first part of this book summarizes the knowledge acquired on the molecular entities that play a role in tumor angiogenesis and their mechanisms of action. Furthermore, the identification of molecular markers and their validation as predictive and/or prognostic tools is reviewed. In the second and most important part, the clinical applications of anti-angiogenic treatments are documented for a wide variety of tumors. In particular, the modes of combination with other targeted and/or cytotoxic cancer therapies are presented.​

Anti-Angiogenesis Drug Discovery and Development

Atta-ur-Rahman,Muhammad Iqbal Choudhary
Anti Angiogenesis Drug Discovery and Development Book PDF

Author : Atta-ur-Rahman,Muhammad Iqbal Choudhary
Publisher : Elsevier
Page : 326 pages
File Size : 41,7 Mb
Release : 2015-06-16
Category : Science
ISBN : 9780128039649

Get Book

Anti-Angiogenesis Drug Discovery and Development by Atta-ur-Rahman,Muhammad Iqbal Choudhary Pdf

The inhibition of angiogenesis is an effective mechanism of slowing down tumor growth and malignancies. The process of induction or pro-angiogenesis is highly desirable for the treatment of cardiovascular diseases, wound healing disorders, and more. Efforts to understand the molecular basis, both for inhibition and induction, have yielded fascinating results. Originally published by Bentham and now distributed by Elsevier, Anti-Angiogenesis Drug Discovery and Development, Volume 2 is an compilation of well-written reviews on various aspects of the anti-angiogenesis process. These reviews have been contributed by leading practitioners in drug discovery science and highlight the major developments in this exciting field in the last two decades. These reader-friendly chapters cover topics of great scientific importance, many of which are considered significant medical breakthroughs, making this book excellent reading both for the novice as well as for expert medicinal chemists and clinicians. Edited and written by leading experts in angiogenesis drug development Reviews recent advances in the field, such as coverage of anti-angiogenetic drugs in ovarian cancer Reports current strategies and future outlook for anti-angiogenic therapy and cardiovascular diseases

Antiangiogenic Agents in Cancer Therapy

Beverly A. Teicher,Lee M. Ellis
Antiangiogenic Agents in Cancer Therapy Book PDF

Author : Beverly A. Teicher,Lee M. Ellis
Publisher : Springer Science & Business Media
Page : 559 pages
File Size : 48,8 Mb
Release : 2008-01-08
Category : Medical
ISBN : 9781597451840

Get Book

Antiangiogenic Agents in Cancer Therapy by Beverly A. Teicher,Lee M. Ellis Pdf

This volume represents a compendium of scientific findings and approaches to the study of angiogenesis in cancer. The second edition of Antiangiogenic Agents in Cancer Therapy is intended to give a current perspective on the state-of-the-art of angiogenensis and therapy directed at this process. Antiangiogenesis is a dynamic and evolving field in oncology. New therapeutic targets continue to emerge followed by the rapid development of new therapeutic agents to be investigated in clinical trials. Optimizing the therapeutic potential of antiangiogenic agents in combination with the other therapies in the armamentarium to fight cancer will be an on-going challenge.

Metronomic Chemotherapy

Guido Bocci,Giulio Francia
Metronomic Chemotherapy Book PDF

Author : Guido Bocci,Giulio Francia
Publisher : Springer
Page : 295 pages
File Size : 47,6 Mb
Release : 2014-09-04
Category : Medical
ISBN : 9783662436042

Get Book

Metronomic Chemotherapy by Guido Bocci,Giulio Francia Pdf

This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic.

Inflammation and Angiogenesis

Domenico Ribatti
Inflammation and Angiogenesis Book PDF

Author : Domenico Ribatti
Publisher : Springer
Page : 111 pages
File Size : 43,7 Mb
Release : 2017-11-08
Category : Medical
ISBN : 9783319684482

Get Book

Inflammation and Angiogenesis by Domenico Ribatti Pdf

This book is focused on the analysis of the role played by immune cell components in the angiogenic process associated with inflammation and tumor growth. Both innate and adaptive immune cells are involved in the mechanisms of endothelial cell proliferation, migration and activation, through the production and release of a large spectrum of pro-angiogenic mediators. These may create the specific microenvironment that favors an increased rate of tissue vascularization. The link between chronic inflammation and tumorigenesis was first proposed by Rudolf Virchow in 1863 after the observation that infiltrating leukocytes are a hallmark of tumors and first established a causative connection between the lymph reticular infiltrate at sites of chronic inflammation and the development of cancer. Tumors were described as wounds that never heal and surgeons have long described the tendency of tumors to recur in healing resection margin and it has been reported that wound healing environment provides an opportunistic matrix for tumor growth. As angiogenesis is the result of a net balance between the activities exerted by positive and negative regulators, this book will also provide information on some anti-angiogenic properties of immune cells that may be utilized for a potential pharmacological use as anti-angiogenic agents in inflammation as well as in cancer. The work is written for researchers in the field and also for graduate students which approach this matter.

Tumor Vascularization

Domenico Ribatti,Francesco Pezzella
Tumor Vascularization Book PDF

Author : Domenico Ribatti,Francesco Pezzella
Publisher : Academic Press
Page : 198 pages
File Size : 49,7 Mb
Release : 2020-01-21
Category : Science
ISBN : 9780128194942

Get Book

Tumor Vascularization by Domenico Ribatti,Francesco Pezzella Pdf

Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a valuable source for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in tumor progression and blood vessels. Explains new, non-orthodox concepts recently developed and related to the modality of growth of tumor blood vessels Provides information on the types of angiogenesis, non-angiogenesis dependent growth and vascular co-option, discussing both their similarities and differences Encompasses a discussion on clinical implications of tumor vascularization to translate research findings into treatment

Physiologic and Pathologic Angiogenesis

Dan Simionescu,Agneta Simionescu
Physiologic and Pathologic Angiogenesis Book PDF

Author : Dan Simionescu,Agneta Simionescu
Publisher : BoD – Books on Demand
Page : 466 pages
File Size : 52,8 Mb
Release : 2017-04-05
Category : Medical
ISBN : 9789535130239

Get Book

Physiologic and Pathologic Angiogenesis by Dan Simionescu,Agneta Simionescu Pdf

The purpose of this book is to highlight novel advances in the field and to incentivize scientists from a variety of fields to pursue angiogenesis as a research avenue. Blood vessel formation and maturation to capillaries, arteries, or veins is a fascinating area which can appeal to multiple scientists, students, and professors alike. Angiogenesis is relevant to medicine, engineering, pharmacology, and pathology and to the many patients suffering from blood vessel diseases and cancer, among others. We are hoping that this book will become a source of inspiration and novel ideas for all.

Angiogenesis Modulations in Health and Disease

Shaker A. Mousa,Paul J. Davis
Angiogenesis Modulations in Health and Disease Book PDF

Author : Shaker A. Mousa,Paul J. Davis
Publisher : Springer Science & Business Media
Page : 206 pages
File Size : 49,9 Mb
Release : 2014-07-08
Category : Medical
ISBN : 9789400764675

Get Book

Angiogenesis Modulations in Health and Disease by Shaker A. Mousa,Paul J. Davis Pdf

This book is a major update of novel targets in angiogenesis modulation, including pro- and anti-angiogenesis. There is in-depth coverage of preclinical and clinical methods and models, investigational status, and clinical applications. The impact of nanotechnology in advancing the applications of pro-and anti-angiogenesis strategies is also highlighted, along with stem cell and biotechnologies in research and development of angiogenesis modulating targets.

Angiogenesis & Therapeutic Targets in Cancer

Malay Chatterjee,Ajay Rana,Basabi Rana
Angiogenesis Therapeutic Targets in Cancer Book PDF

Author : Malay Chatterjee,Ajay Rana,Basabi Rana
Publisher : Bentham Science Publishers
Page : 238 pages
File Size : 44,8 Mb
Release : 2010
Category : Medical
ISBN : 9781608050079

Get Book

Angiogenesis & Therapeutic Targets in Cancer by Malay Chatterjee,Ajay Rana,Basabi Rana Pdf

Angiogenesis plays rate limiting roles in tumor growth and invasion. Angiogenesis inhibition has been proposed as a general strategy to fight against cancers. This book covers different therapeutic targets for angiogenesis interventions with emphasis on c