Basic Biology And Clinical Aspects Of Inflammation

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Basic Biology and Clinical Aspects of Inflammation

Robert F. Diegelmann,Charles E. Chalfant
Basic Biology and Clinical Aspects of Inflammation Book PDF

Author : Robert F. Diegelmann,Charles E. Chalfant
Publisher : Bentham Science Publishers
Page : 494 pages
File Size : 43,8 Mb
Release : 2016-03-07
Category : Medical
ISBN : 9781681082271

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Basic Biology and Clinical Aspects of Inflammation by Robert F. Diegelmann,Charles E. Chalfant Pdf

Basic Biology and Clinical Aspects of Inflammation provides information about the critical cells and biochemical mediators involved in the complex process of inflammation. Readers are introduced to the basic scientific background on the subject, after which the book progresses towards translational research in clinical settings. Topics covered in this volume include, the modulation of inflammation during normal and chronic wound healing, altered metabolism during inflammation processes, the effect of ageing on inflammatory processes, as well as details about the underlying molecular processes behind specific clinical pathologies that are driven by excessive inflammation in the body (allergic reactions, type 2 diabetes, cardiac and vascular disease, arthritis, periodontal disease, inflammatory bowel disease and neuroinflammation). The volume also provides the latest information on pharmacotherapy for inflammation and interesting contributions towards the mathematical modeling and network analysis of inflammation. Basic Biology and Clinical Aspects of Inflammation features contributions from by a distinguished group of international researchers and clinicians highly recognized for their specific expertise in the field of inflammation. The information presented in this reference is useful to academics, medical professionals, health care regulators and pharmaceutical scientists.

Basic Biology and Clinical Aspects of Inflammation

Bentham Science Publishers
Basic Biology and Clinical Aspects of Inflammation Book PDF

Author : Bentham Science Publishers
Publisher : Unknown
Page : 494 pages
File Size : 49,8 Mb
Release : 2016-03-07
Category : Biology
ISBN : 1681082284

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Basic Biology and Clinical Aspects of Inflammation by Bentham Science Publishers Pdf

"Basic Biology and Clinical Aspects of Inflammation provides information about the critical cells and biochemical mediators involved in the complex process of inflammation. Readers are introduced to the basic scientific background on the subject, after whi"

Fundamentals of Inflammation

Charles N. Serhan,Peter A. Ward,Derek W. Gilroy
Fundamentals of Inflammation Book PDF

Author : Charles N. Serhan,Peter A. Ward,Derek W. Gilroy
Publisher : Cambridge University Press
Page : 489 pages
File Size : 47,8 Mb
Release : 2010-04-26
Category : Medical
ISBN : 9780521887298

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Fundamentals of Inflammation by Charles N. Serhan,Peter A. Ward,Derek W. Gilroy Pdf

The acute inflammatory response is the body's first system of alarm signals that are directed toward containment and elimination of microbial invaders. Uncontrolled inflammation has emerged as a pathophysiologic basis for many widely occurring diseases in the general population. This book provides an introduction to the cell types, chemical mediators, and general mechanisms of the host's first response to invasion.

Translational Inflammation

Anonim
Translational Inflammation Book PDF

Author : Anonim
Publisher : Academic Press
Page : 294 pages
File Size : 42,6 Mb
Release : 2018-11-24
Category : Medical
ISBN : 9780128138335

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Translational Inflammation by Anonim Pdf

Translational Inflammation links laboratory and clinical data within primary and secondary care to clinical research data and offers a holistic and innovative approach to chronic inflammation and ageing. Understanding the role of inflammation as a part of clinical disease states is becoming a valuable tool in both direct treatment and the development of therapeutics. Translational Inflammation, the 4th volume in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology. Emphasizes the role of inflammation in disease and therapeutic approaches Integrates broad concepts relating inflammation to other fields Offers a bridge to review literature and primary research on the inflammatory response towards medical application

Cancer and Inflammation Mechanisms

Yusuke Hiraku,Shosuke Kawanishi,Hiroshi Ohshima
Cancer and Inflammation Mechanisms Book PDF

Author : Yusuke Hiraku,Shosuke Kawanishi,Hiroshi Ohshima
Publisher : Wiley
Page : 0 pages
File Size : 40,7 Mb
Release : 2014-03-31
Category : Science
ISBN : 1118160304

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Cancer and Inflammation Mechanisms by Yusuke Hiraku,Shosuke Kawanishi,Hiroshi Ohshima Pdf

A new perspective on the link between inflammation and cancer Inflammation is the human body’s normal biological response to threats in the modern world, as well as a defense against the harmful influence of pathogens, the environment, and poor nutrition. But what happens when the inflammatory response is triggered repeatedly and sustained for long periods of time? Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects discusses the mechanisms by which chronic inflammation can lead to cancer, the various causative agents, and possible prevention methods. A compilation of the latest information coming out of the various fields of cancer research, this book provides a detailed look at inflammation-related carcinogenesis from the perspective of researchers at the forefront of the field. It takes an interdisciplinary approach to the topic, and provides comprehensive information about the major factors at work in inflammation, cancer, and the intersection of the two conditions. Topics include: A general overview of inflammation-related cancer The biochemistry of inflammation and its effects on DNA Molecular biology and the role of microRNA in carcinogenesis Specific causative agents including oncogenic viruses, asbestos, and nanomaterial Anti-inflammatories, nutraceuticals, and other preventative measures A deeper understanding of the mechanisms behind inflammation-related carcinogenesis can lead to better patient outcomes by improving diagnostics and prevention, as well as altering the approach to treatment. Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects provides the knowledge base researchers need to push the field forward.

Inflammation and the Microcirculation

D. Neil Granger,Elena Senchenkova
Inflammation and the Microcirculation Book PDF

Author : D. Neil Granger,Elena Senchenkova
Publisher : Morgan & Claypool Publishers
Page : 99 pages
File Size : 51,7 Mb
Release : 2010
Category : Medical
ISBN : 9781615041657

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Inflammation and the Microcirculation by D. Neil Granger,Elena Senchenkova Pdf

The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References

The Resolution of Inflammation

Adriano Rossi,Deborah A. Sawatzky
The Resolution of Inflammation Book PDF

Author : Adriano Rossi,Deborah A. Sawatzky
Publisher : Springer Science & Business Media
Page : 240 pages
File Size : 48,9 Mb
Release : 2008-03-17
Category : Medical
ISBN : 9783764375065

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The Resolution of Inflammation by Adriano Rossi,Deborah A. Sawatzky Pdf

This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.

Biology of C Reactive Protein in Health and Disease

Waliza Ansar,Shyamasree Ghosh
Biology of C Reactive Protein in Health and Disease Book PDF

Author : Waliza Ansar,Shyamasree Ghosh
Publisher : Springer
Page : 301 pages
File Size : 54,9 Mb
Release : 2016-03-23
Category : Medical
ISBN : 9788132226802

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Biology of C Reactive Protein in Health and Disease by Waliza Ansar,Shyamasree Ghosh Pdf

This book offers a comprehensive study of C-reactive protein (CRP) belonging to the pentraxin family, including a brief history of CRP, its structure, synthesis and evolution. Focusing on the emerging role of CRP and its clinical application in the field of disease biology, it details the pathophysiological role of CRP in a host of diseases such as cardiovascular disease, diabetes, cancers, rheumatoid arthritis and infectious diseases and others. It also discusses the role of innate immunity and acute phase response (APR) and their key mediators in the host body in response to tissue injury, infection, trauma or surgery, immunological disorders or neoplastic growth. CRP’s significance in inflammation is highlighted, and its importance as a clinical marker in cardiovascular disease, its functional significance in Leishmania and Plasmodium infections, its association with the development of insulin resistance in type 2 diabetes mellitus, and its role in cancer are discussed in detail. The book also includes clinical data studies and presents the latest research advances to further readers’ understanding of CRP.

Vascular Responses to Pathogens

Felicity N.E. Gavins,Karen Y. Stokes
Vascular Responses to Pathogens Book PDF

Author : Felicity N.E. Gavins,Karen Y. Stokes
Publisher : Academic Press
Page : 252 pages
File Size : 53,8 Mb
Release : 2015-10-31
Category : Medical
ISBN : 9780128013250

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Vascular Responses to Pathogens by Felicity N.E. Gavins,Karen Y. Stokes Pdf

Vascular Responses to Pathogens focuses on the growing research from leaders in the field for both the short and long-term impact of pathogens on the vasculature. It discusses various organisms, including bacteria, parasites, and viruses, and their role in key events leading to vascular disease. Formatted to discuss the topic of the interaction of pathogens with the vascular rather than individual diseases described separately, this reference demonstrates that common mechanisms are at play in many different diseases because they have a similar context, their vasculature. This all-inclusive reference book is a must-have tool for researchers and practicing clinicians in the areas of vascular biology, microvasculature, cardiology, and infectious disease. Covers a wide spectrum of organisms and provides analysis of pathogens and current therapeutic strategies in the context of their vasculature Provides detailed perspectives on key components contributing to vascular pathogens from leaders in the field Interfaces between both vascular biology and microbiology by encompassing information on how pathogens affect both macro and microvasculature Includes coverage of the clinical aspects of sepsis and current therapeutic strategies and anti-sepsis drugs

Biochemistry of Inflammation

J. Whicher,S.W. Evans
Biochemistry of Inflammation Book PDF

Author : J. Whicher,S.W. Evans
Publisher : Springer Science & Business Media
Page : 316 pages
File Size : 40,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401129961

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Biochemistry of Inflammation by J. Whicher,S.W. Evans Pdf

Our understanding of inflammation has increased rapidly in recent years, due in large part to the impact of molecular biology and gene identification and cloning. This book brings together ideas from a number of different biochemical disciplines which are frequently not integrated. The first chapter gives a visual overview of the subject; the remaining chapters are organized into three themes: the affector molecules, the regulatory components and the processes of inflammation itself. This book is essential reading for the busy physician or pathologist who wants to be up-to-date with the latest developments in immunology as they affect the diagnosis and treatment of many conditions.

Measuring Immunity

Michael T. Lotze,Angus W. Thomson
Measuring Immunity Book PDF

Author : Michael T. Lotze,Angus W. Thomson
Publisher : Elsevier
Page : 736 pages
File Size : 42,5 Mb
Release : 2011-05-04
Category : Medical
ISBN : 0080479332

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Measuring Immunity by Michael T. Lotze,Angus W. Thomson Pdf

Most of the diseases of modern mankind involve either acute or chronic inflammation. Measuring Immunity integrates the current information available on biomarkers and surrogate assays into a single handbook. It highlights the principles behind various applications, gives a brief summary on how they are conducted and provides detailed and critical analyses of murine models of immunity, clinical trials, and tests to predict utility and benefit. Measuring Immunity is indispensable for scientists and clinicians interested in the clinical applications of modern immunobiology. * Defines which assays of immune function are helpful in the assessment of clinical disorders involving inflammation and immunity * Assesses the dynamics of cellular and soluble factors in the peripheral blood using modern techniques * Includes basic science foundations as well as the approaches currently applied

Molecular Pathology

William B. Coleman,Gregory J. Tsongalis
Molecular Pathology Book PDF

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 802 pages
File Size : 52,8 Mb
Release : 2017-11-09
Category : Medical
ISBN : 9780128027875

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Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Inflammation and Natural Products

Sreeraj Gopi,Augustine Amalraj,Ajaikumar B. Kunnumakkara,Sabu Thomas
Inflammation and Natural Products Book PDF

Author : Sreeraj Gopi,Augustine Amalraj,Ajaikumar B. Kunnumakkara,Sabu Thomas
Publisher : Academic Press
Page : 420 pages
File Size : 53,6 Mb
Release : 2021-01-19
Category : Medical
ISBN : 9780128192191

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Inflammation and Natural Products by Sreeraj Gopi,Augustine Amalraj,Ajaikumar B. Kunnumakkara,Sabu Thomas Pdf

Approx.446 pages Approx.446 pages

Inflammation and Immunity in Depression

Bernhard Baune
Inflammation and Immunity in Depression Book PDF

Author : Bernhard Baune
Publisher : Academic Press
Page : 636 pages
File Size : 41,6 Mb
Release : 2018-05-23
Category : Medical
ISBN : 9780128110744

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Inflammation and Immunity in Depression by Bernhard Baune Pdf

Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system Explores translational potential of targeting immune dysfunction for clinical interventions

Inflammation, Advancing Age and Nutrition

Irfan Rahman,Debasis Bagchi
Inflammation Advancing Age and Nutrition Book PDF

Author : Irfan Rahman,Debasis Bagchi
Publisher : Academic Press
Page : 394 pages
File Size : 40,7 Mb
Release : 2013-09-03
Category : Technology & Engineering
ISBN : 9780123978073

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Inflammation, Advancing Age and Nutrition by Irfan Rahman,Debasis Bagchi Pdf

The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature aging based on personalized medicine. This book is a valuable resource for health professionals, scientists and researchers, nutritionists, health practitioners, students and for all those who wish to broaden their knowledge in the allied field. Includes models of aging, including worm, mouse and human Explores the relationship of inflammation with diseases, including ocular health, Alzheimer's and Parkinson's disease, and muscle health Encompasses a variety of lifestyle impacts, including diet, exercise and nutrition Includes suggested nutritional interventions