Biological Functions Of Microtubules And Related Structures

Author : Hikoichi Sakai,Hideo Mohri,Gary G. Borisy
Publisher : Academic Press
Page : 474 pages
File Size : 51,6 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483272207

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Biological Functions of Microtubules and Related Structures by Hikoichi Sakai,Hideo Mohri,Gary G. Borisy Pdf

Biological Functions of Microtubules and Related Structures is a compendium of papers presented at the 13th Oji International Seminar on The Biological Functions of Microtubules and Related Structures, held at Komaba Eminence in Tokyo in November, 1981. The papers discuss the molecular function of tubulin in various biological processes or events. The book is divided into six sections focusing on the various aspects of the functions and structures of microtubules -- the biochemistry and molecular biology of tubulin, including regulation of microtubule assembly; microtubule-dynein systems and other proteins in cell motility; microtubules and related proteins in mitosis; the interactions of cytoskeletal components; the cytoskeleton; and microtubules in membrane functions and transport. Biochemists, biologists, and molecular biologists will find the book interesting.

Author : Hikoichi Sakai
Publisher : Unknown
Page : 453 pages
File Size : 42,8 Mb
Release : 1982
Category : Microtubules
ISBN : 012615080X

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Biological functions of microtubules and related structures by Hikoichi Sakai Pdf

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 48,9 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Antonio Tito Fojo
Publisher : Springer Science & Business Media
Page : 629 pages
File Size : 43,9 Mb
Release : 2009-01-14
Category : Medical
ISBN : 9781597453363

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The Role of Microtubules in Cell Biology, Neurobiology, and Oncology by Antonio Tito Fojo Pdf

This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and investigates the potential of microtubules in cancer therapy.

Author : Anne Straube
Publisher : Humana Press
Page : 319 pages
File Size : 44,8 Mb
Release : 2017-04-30
Category : Science
ISBN : 1493961853

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Microtubule Dynamics by Anne Straube Pdf

Microtubules are at the heart of cellular self-organization, and their dynamic nature allows them to explore the intracellular space and mediate the transport of cargoes from the nucleus to the outer edges of the cell and back. In Microtubule Dynamics: Methods and Protocols, experts in the field provide an up-to-date collection of methods and approaches that are used to investigate microtubule dynamics in vitro and in cells. Beginning with the question of how to analyze microtubule dynamics, the volume continues with detailed descriptions of how to isolate tubulin from different sources and with different posttranslational modifications, methods used to study microtubule dynamics and microtubule interactions in vitro, techniques to investigate the ultrastructure of microtubules and associated proteins, assays to study microtubule nucleation, turnover, and force production in cells, as well as approaches to isolate novel microtubule-associated proteins and their interacting proteins. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Definitive and practical, Microtubule Dynamics: Methods and Protocols provides the key protocols needed by novices and experts on how to perform a broad range of well-established and newly-emerging techniques in this vital field.

Author : James Spudich
Publisher : Unknown
Page : 0 pages
File Size : 41,9 Mb
Release : 1996
Category : Actin
ISBN : 0824331737

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The Cytoskeleton by James Spudich Pdf

Author : John J. Correia,Leslie Wilson
Publisher : Academic Press
Page : 472 pages
File Size : 40,9 Mb
Release : 2013-08-20
Category : Science
ISBN : 9780124078888

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Microtubules, in vitro by John J. Correia,Leslie Wilson Pdf

There continues to be intense interest in the microtubule cytoskeleton; the assembly, structure and regulation of microtubules; and the numerous motors and accessory proteins that control cell cycle, dynamics, organization and transport. The field continues to grow and explore new aspects of these issues driven immensely by developments in optical imaging and tracking techniques. This Second Edition brings together current research and protocols in the field of microtubules in vitro and will serve as a valuable tool for cell biologists, biophysicists and pharmacologists who study the microtubule cytoskeleton, as well as for researchers in the biomedical and biotechnology communities with interest in developing drugs that target microtubules, MAPS and motors. Chapters reflect experimental procedures and new developments in the field of microtubule in vitro research Combines classical approaches and modern technologies Presents easy-to-use protocols and thorough background information, compiled by leaders in the field

Author : Pierre Dustin
Publisher : Springer Science & Business Media
Page : 499 pages
File Size : 42,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642696527

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Microtubules by Pierre Dustin Pdf

The decision, in 1975, to write alone a monograph on micro tubules was not without risks. While I was familiar from its start in Brussels in 1934 with the work on col chicine and other mitotic poisons, the literature on microtubules was, 8 years ago, already increasing at an impressive rate. However, this monograph, which, contrary to other works on microtubules, tried to cover the whole field of research, from the fundamentals of the tubulin molecule and the possible role of these organelles in some aspects of human pathology, to some medical applications of microtubule poisons, has been accepted as a useful tool for workers in these fields. Since 1976, (date of the last references mentioned in the monograph) until the middle of 1983, papers on microtubule research have literally been pouring in, at the rate of several hundred a year. This may justify a second edition, although the considerable difficulties in keeping the size of the book within the same limits while not forgetting to mention some important work, could not be overlooked. The need for an entirely revised and rewritten edition prompted this new venture and was possible with the help of the considerable amount of reprints kindly sent to me day after day over the years. This work would have been unthinkable if the author had not maintained the same enthusiasm for microtubule research, which has been disclosing new facts every day.

Author : Wei Yamauchi,Antonio Sokic
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 54,8 Mb
Release : 2011-12
Category : Tubulins
ISBN : 1621001415

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Tubulin by Wei Yamauchi,Antonio Sokic Pdf

Tubulin is one of several members of a small family of globular proteins. The most common members of the tubulin family are α-tubulin and β-tubulin, the proteins that make up microtubules. In this book the authors present topical research in the study of the structure, functions and roles in disease of tubulin. Topics discussed in this compilation include microtubule plus-end tracking proteins in neuronal development and nervous system disorders; trypanosome tubulin molecules as targets for drug and vaccine development for protozoan infections; tubulin inhibitors as vascular disrupting agents and evolution and co-evolution of tubulin's carboxy-terminal tails and mitochondria.

Author : Edward Bittar
Publisher : Academic Press
Page : 542 pages
File Size : 46,8 Mb
Release : 1992-01-08
Category : Science
ISBN : 9781559383103

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Metabolic Pumps and Intracellular Homeostasis, Hormones and Cell Function, Intercellular Communication, Cell Motility and Contractility, Part B by Edward Bittar Pdf

Volumes 5A and 5B of Fundamentals of Medical Cell Biology are a treatment of several key subjects, including cellular signaling. One profitable way to tackle both volumes is to read them with care but without endeavouring to master most of the details. Then should follow a more plodding study, chapter by chapter. Such a strategy is also urged in respect of the preceding volumes. Although each chapter is only as detailed as space permits, it should in the case of the student serve as an incentive to the study of the original papers.

Author : Jose C. Jimenez-Lopez
Publisher : BoD – Books on Demand
Page : 344 pages
File Size : 49,5 Mb
Release : 2017-05-17
Category : Science
ISBN : 9789535131694

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Cytoskeleton by Jose C. Jimenez-Lopez Pdf

The cytoskeleton is a highly dynamic intracellular platform constituted by a three-dimensional network of proteins responsible for key cellular roles as structure and shape, cell growth and development, and offering to the cell with "motility" that being the ability of the entire cell to move and for material to be moved within the cell in a regulated fashion (vesicle trafficking). The present edition of Cytoskeleton provides new insights into the structure-functional features, dynamics, and cytoskeleton's relationship to diseases. The authors' contribution in this book will be of substantial importance to a wide audience such as clinicians, researches, educators, and students interested in getting updated knowledge about molecular basis of cytoskeleton, such as regulation of cell vital processes by actin-binding proteins as cell morphogenesis, motility, their implications in cell signaling, as well as strategies for clinical trial and alternative therapies based in multitargeting molecules to tackle diseases, that is, cancer.

Author : Samantha Fowler,Rebecca Roush,James Wise
Publisher : Unknown
Page : 618 pages
File Size : 41,6 Mb
Release : 2018-01-07
Category : Science
ISBN : 9888407457

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Concepts of Biology by Samantha Fowler,Rebecca Roush,James Wise Pdf

Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.

Author : Jesus Avila
Publisher : CRC Press
Page : 280 pages
File Size : 45,7 Mb
Release : 1989-10-31
Category : Medical
ISBN : 0849355273

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Microtubule Proteins by Jesus Avila Pdf

This work focuses on the structural and functional description of the microtubule proteins. The objective of the authors is to establish a relationship between the structure of microtubule proteins and the functions in which these polymers are involved. This book covers topics which have been treated only in a preliminary manner in previous works, such as microtubule dynamics and microtubule poisons. Microtubules display a variety of cellular roles and are vital for the separation and correct distribution of chromosomes during cell division. They also play an important role in morphogenesis, intracellular transport, secretion, and motility. Microtubule Proteins is a concise, easy-to-read text which is particularly of interest to cell biologists, chemists, neurochemists, and graduate students interested in cell biology.

Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1972 pages
File Size : 51,8 Mb
Release : 1984
Category : Medicine
ISBN : MINN:31951M01375430O

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National Library of Medicine Current Catalog by National Library of Medicine (U.S.) Pdf

Author : A. Gorio,J.R. Perez-Polo,J. de Vellis,B. Haber
Publisher : Springer Science & Business Media
Page : 701 pages
File Size : 46,5 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783642731488

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Neural Development and Regeneration by A. Gorio,J.R. Perez-Polo,J. de Vellis,B. Haber Pdf

Data of all relevant aspects of neuronal cell growth and differentiation are presented in this volume. Regulation of expression, storage and release of nerve growth factors, receptor control and the cellular responses to growth factors are comprehensively discussed. Treated are also influences of various neurotransmitters on neuronal morphogenesis and new results of interactions of cells and mediators of the immune, endocrine and nervous system. Special emphasis is given to those factors regulating regeneration and nerve spreading after injuries of the nerve tissue.