Calreticulin

Author : Marek Michalak
Publisher : Springer Science & Business Media
Page : 217 pages
File Size : 49,8 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783662062036

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Calreticulin by Marek Michalak Pdf

This book is about calreticulin, a multifunctional calcium binding protein first discovered over 20 years ago. The protein has been described in various locations: endoplasmic reticulum, nuclear envelope, cytoplasmic granules, nucleus, cell surface and even secreted into the blood stream. This volume outlines the newly discovered functions for calreticulin including its control of calcium homeostasis, modulation of steroid-sensitive gene expression, control of viral RNA replication, modulation of nuclear transport, role in T lymphocyte activation and cytotoxic killing, chaperone function, control of adhesion-dependent signaling via integrins, possible role in the biology of ticks, in the pathology of autoimmune diseases and in blood function.

Author : Paul Eggleton,Marek Michalak
Publisher : Springer Science & Business Media
Page : 306 pages
File Size : 47,8 Mb
Release : 2003-07-31
Category : Science
ISBN : 0306478455

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Calreticulin by Paul Eggleton,Marek Michalak Pdf

The book focuses on the latest discoveries on calreticulin, calnexin and other endoplasmic reticulum proteins. Calreticulin has been implicated to affect diverse cellular function and play a role in many pathologies including protein folding disorders, cardiac pathologies, cancer and autoimmunity. This book contains contributions from the world leaders in the area of endoplasmic reticulum function, protein folding, Calcium homeostasis and autoimmunity. It raises many intriguing questions about calreticulin, calnexin and the endoplasmic reticulum and gives a unique opportunity to realize the significance of these calcium-binding chaperones. The book is unique in every respect and we are not aware of any other publication focusing on these aspects of endoplasmic reticulum biology. Because of a central role of endoplasmic reticulum, calreticulin and calnexin in virtually all cellular functions, the book should be of interest to everyone in the biological sciences.

Author : Marek Michalak
Publisher : Unknown
Page : 211 pages
File Size : 42,6 Mb
Release : 1996
Category : Calreticulin
ISBN : 1570593108

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Calreticulin by Marek Michalak Pdf

This book is about calreticulin, a multifunctional calcium binding protein first discovered over 20 years ago. The protein has been described in various locations: endoplasmic reticulum, nuclear envelope, cytoplasmic granules, nucleus, cell surface and even secreted into the blood stream. This volume outlines the newly discovered functions for calreticulin including its control of calcium homeostasis, modulation of steroid-sensitive gene expression, control of viral RNA replication, modulation of nuclear transport, role in T lymphocyte activation and cytotoxic killing, chaperone function, control of adhesion-dependent signaling via integrins, possible role in the biology of ticks, in the pathology of autoimmune diseases and in blood function.

Author : Martin Schröder
Publisher : Unknown
Page : 0 pages
File Size : 41,6 Mb
Release : 2010
Category : Endoplasmic reticulum
ISBN : 161668173X

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Molecular Chaperones of the Endoplasmic Reticulum by Martin Schröder Pdf

An important function of the endoplasmic reticulum is the folding of newly synthesised polypeptide chains. Several general and specialised chaperones operate in the endoplasmic reticulum to assist protein folding. This book reviews our current knowledge of molecular chaperones of the ER, including the HSP70 class chaperones BiP and GRP170, their DnaJ and GrpE co-chaperones, the HSP90 class chaperone GRP94, and the lectin chaperones calnexin, calmegin, and calreticulin. This book provides an overview of the biochemistry and physical chemistry of molecular chaperones with emphasis on molecular chaperones of the endoplasmic reticulum.

Author : Luis B. Agellon,Marek Michalak
Publisher : Springer Nature
Page : 329 pages
File Size : 52,7 Mb
Release : 2021-05-29
Category : Science
ISBN : 9783030676964

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Cellular Biology of the Endoplasmic Reticulum by Luis B. Agellon,Marek Michalak Pdf

This book provides a comprehensive overview of the biology of the endoplasmic reticulum (ER) and the associated ER proteins, it discusses their structure, function and signaling mechanisms in the cell and their role in disease. This book also offers insights into the practical aspects of research and demonstrates the use of non-mammalian models to study the structure and function of the ER. Written by leading experts in the field, the book enables readers to gain a thorough understanding of current ER biology. It is intended for scientists and clinical researchers working on the endoplasmic reticulum in all its various roles and facets in health and disease.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 55,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Jules Hoffmann
Publisher : Unknown
Page : 316 pages
File Size : 54,7 Mb
Release : 2004
Category : Drosophila melanogaster
ISBN : NWU:35557000119584

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Primitive Immune Systems by Jules Hoffmann Pdf

Author : Anonim
Publisher : Academic Press
Page : 248 pages
File Size : 47,6 Mb
Release : 2021-10-29
Category : Science
ISBN : 9780323899406

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Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A by Anonim Pdf

Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A, Volume 365 in the International Review of Cell and Molecular Biology series reviews and details current advances in cell and molecular biology. Chapters in this new release include MPN a continuum of different disease entities, Bone marrow microenvironment of MPN, Extramedullary hemopoiesis in MPN, The JAK2 mutation, Calreticulin mutations in myeloproliferative neoplasms, and Cytogenetic abnormalities and non-driver mutations in MPN. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology. Publishes only invited review articles on selected topics Authored by established and active cell and molecular biologists and drawn from international sources Offers a wide range of perspectives on specific subjects

Author : Anonim
Publisher : Unknown
Page : 612 pages
File Size : 53,6 Mb
Release : 2002
Category : Disease susceptibility
ISBN : UCSD:31822023098817

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Thrombosis and Haemostasis by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 500 pages
File Size : 51,9 Mb
Release : 2009
Category : Biochemistry
ISBN : MINN:31951P01098558Y

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Biochemistry and Cell Biology by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 1086 pages
File Size : 47,5 Mb
Release : 2007
Category : Cancer
ISBN : IND:30000121560811

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Cancer Research by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 624 pages
File Size : 52,9 Mb
Release : 1994
Category : Medicine, Experimental
ISBN : NWU:35558003143472

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European Journal of Clinical Investigation by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 630 pages
File Size : 53,9 Mb
Release : 2003
Category : Cytology
ISBN : UOM:39015056611547

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Journal of Cell Science by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 1048 pages
File Size : 48,5 Mb
Release : 1996
Category : Entomology
ISBN : UCAL:B5002846

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Journal of Medical Entomology by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 732 pages
File Size : 50,8 Mb
Release : 2005
Category : Immunology
ISBN : UIUC:30112075226032

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The Journal of Immunology by Anonim Pdf