Carcinogenicity Testing

Author : Kirk T. Kitchin
Publisher : CRC Press
Page : 918 pages
File Size : 43,6 Mb
Release : 2021-12-17
Category : Science
ISBN : 9781000105469

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Carcinogenicity by Kirk T. Kitchin Pdf

Offers comprehensive coverage of currently available cancer predictors, the most recent research on carcinogenicity, and the design and interpretation of carcinogenicity experiments. Presents mouse, rat, and human carcinogenicity data for the liver, kidney, breast, cervix, prostate, hematopoietic system, colon, skin, urinary bladder, mouth, stomach, thyroid, and pancreas.

Author : Kirk T. Kitchin
Publisher : CRC Press
Page : 924 pages
File Size : 53,8 Mb
Release : 1998-10-29
Category : Science
ISBN : 0824798937

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Carcinogenicity by Kirk T. Kitchin Pdf

Offers comprehensive coverage of currently available cancer predictors, the most recent research on carcinogenicity, and the design and interpretation of carcinogenicity experiments. Presents mouse, rat, and human carcinogenicity data for the liver, kidney, breast, cervix, prostate, hematopoietic system, colon, skin, urinary bladder, mouth, stomach, thyroid, and pancreas.

Author : International Union against Cancer. Cancer Research Commission. Panel on Carcinogenicity
Publisher : Unknown
Page : 70 pages
File Size : 40,9 Mb
Release : 1969
Category : Carcinogenicity testing
ISBN : UOM:39015003788638

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Carcinogenicity Testing by International Union against Cancer. Cancer Research Commission. Panel on Carcinogenicity Pdf

Author : Organisation for Economic Co-operation and Development
Publisher : Organisation for Economic Co-operation and Development ; [Montréal : Renouf]
Page : 128 pages
File Size : 50,7 Mb
Release : 1981
Category : Chemical industry
ISBN : 9264122214

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OECD Guidelines for Testing of Chemicals by Organisation for Economic Co-operation and Development Pdf

Author : Harry A. Milman,Elizabeth K. Weisburger
Publisher : Taylor & Francis US
Page : 680 pages
File Size : 48,9 Mb
Release : 1985
Category : Medical
ISBN : UOM:39015009560635

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Handbook of Carcinogen Testing by Harry A. Milman,Elizabeth K. Weisburger Pdf

Author : Michael J. Graziano,David Jacobson-Kram
Publisher : Springer
Page : 206 pages
File Size : 51,8 Mb
Release : 2015-11-02
Category : Medical
ISBN : 9783319220840

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Genotoxicity and Carcinogenicity Testing of Pharmaceuticals by Michael J. Graziano,David Jacobson-Kram Pdf

This book provides an overview of the nonclinical testing strategies that are used to asses and de-risk the genotoxicity and carcinogenicity properties of human pharmaceuticals. It includes a review of relevant ICH guidelines, numerous case studies where follow-up studies were conducted to further investigate positive findings, and practical considerations for the use of alternative and emerging tests. With contributions from recognized experts in the pharmaceutical industry and health authorities, this volume presents a balanced view on the interpretation and application of genotoxicity and carcinogenicity regulatory guidances. Genotoxicity and Carcinogenicity Testing of Pharmaceuticals is a valuable resource for scientists, regulators, and consultants that are engaged in the conduct, reporting, and review of nonclinical studies. This book will also help academicians better understand and appreciate the complexity of the regulations and breadth of toxicology research that are necessary to support the development and marketing of new drugs.

Author : Great Britain. Committee on Carcinogenicity of Chemicals in Food, Consumer Products, and the Environment,Great Britain. Department of Health and Social Security
Publisher : Unknown
Page : 46 pages
File Size : 54,9 Mb
Release : 1982
Category : Carcinogenicity testing
ISBN : IND:30000138827880

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Guidelines for the Testing of Chemicals for Carcinogenicity by Great Britain. Committee on Carcinogenicity of Chemicals in Food, Consumer Products, and the Environment,Great Britain. Department of Health and Social Security Pdf

Author : Adrian Kilcoyne,Phil Ambery,Daniel O'Connor
Publisher : OUP Oxford
Page : 473 pages
File Size : 47,8 Mb
Release : 2013-05-23
Category : Medical
ISBN : 9780191510397

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Pharmaceutical Medicine by Adrian Kilcoyne,Phil Ambery,Daniel O'Connor Pdf

The breadth of the pharmaceutical medicine can be daunting, but this book is designed to navigate a path through the speciality. Providing a broad overview of all topics relevant to the discipline of pharmaceutical medicine, it gives you the facts fast, in a user-friendly format, without having to dive through page upon page of dense text. With 136 chapters spread across 8 sections, the text offers a thorough grounding in issues ranging from medicines regulation to clinical trial design and data management. This makes it a useful revision aid for exams as well as giving you a taster of areas of pharmaceutical medicine adjacent to your current role. For healthcare professionals already working in the field, this book offers a guiding hand in difficult situations as well as supplying rapid access to the latest recommendations and guidelines. Written by authors with experience in the industry and drug regulation, this comprehensive and authoritative guide provides a shoulder to lean on throughout your pharmaceutical career.

Author : OECD
Publisher : OECD Publishing
Page : 15 pages
File Size : 43,6 Mb
Release : 2018-06-27
Category : Electronic
ISBN : 9789264071186

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 451: Carcinogenicity Studies by OECD Pdf

The objective of a long-term carcinogenicity study is to observe test animals for a major portion of their life span for the development of neoplastic lesions during or after exposure to various doses of a test substance by an appropriate route of ...

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Comparative Toxicity of Naturally Occurring Carcinogens
Publisher : National Academies Press
Page : 433 pages
File Size : 41,7 Mb
Release : 1996-02-12
Category : Nature
ISBN : 9780309175715

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Carcinogens and Anticarcinogens in the Human Diet by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Comparative Toxicity of Naturally Occurring Carcinogens Pdf

Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.

Author : Anonim
Publisher : Unknown
Page : 426 pages
File Size : 47,8 Mb
Release : 1984
Category : Carcinogenicity testing
ISBN : MINN:31951002917203F

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Use of Small Fish Species in Carcinogenicity Testing by Anonim Pdf

Author : OECD
Publisher : OECD Publishing
Page : 20 pages
File Size : 40,6 Mb
Release : 2018-06-27
Category : Electronic
ISBN : 9789264071223

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies by OECD Pdf

The objective of a combined chronic toxicity/carcinogenicity study is to identify carcinogenic and the majority of chronic effects, and to determine dose-response relationships following prolonged and repeated exposure. The rat is typically used for ...

Author : Anonim
Publisher : Unknown
Page : 184 pages
File Size : 45,6 Mb
Release : 2005
Category : Animal experimentation
ISBN : 0972709444

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America's War on "carcinogens" by Anonim Pdf

Author : Anthony D. Dayan,Roger William Brimblecombe
Publisher : Unknown
Page : 152 pages
File Size : 49,6 Mb
Release : 1978
Category : Medical
ISBN : UOM:39076006163294

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Carcinogenicity Testing by Anthony D. Dayan,Roger William Brimblecombe Pdf

Author : Anonim
Publisher : Unknown
Page : 280 pages
File Size : 43,8 Mb
Release : 1984
Category : Carcinogenicity testing
ISBN : UOM:39015010673591

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Use of Small Fish Species in Carcinogenicity Testing by Anonim Pdf