Cellular And Molecular Renewal In The Mammalian Body

Author : Ivan L. Cameron,Jack D. Thrasher
Publisher : Academic Press
Page : 433 pages
File Size : 55,6 Mb
Release : 2013-10-22
Category : Nature
ISBN : 9781483271385

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Cellular and Molecular Renewal in the Mammalian Body by Ivan L. Cameron,Jack D. Thrasher Pdf

Cellular and Molecular Renewal in the Mammalian Body concerns the dynamic nature of body constituents at the molecular, organelle, and cellular level of structural organization. Each chapter of this book deals with cellular and molecular renewal, proliferation, and loss, focusing on the body's major macromolecular classes, such as DNA, RNA, proteins, lipids, and carbohydrates. Other topics discussed include the subcellular renewal, DNA stability, regulation of cell proliferation, and changes in mitotic rates. The intracellular sites of RNA synthesis, proteins of the nucleus, and epithelial-mesenchymal interactions are also elaborated. This text likewise covers the brown adipose tissue, histochemistry of polysaccharides, and calcification. This publication is beneficial to students and investigators intending to acquire knowledge of the dynamic nature of body constituents and its influence to the analysis and experimentation of normal, disease, and repair processes within the body.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 42,8 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Ron Milo,Rob Phillips
Publisher : Garland Science
Page : 400 pages
File Size : 43,8 Mb
Release : 2015-12-07
Category : Science
ISBN : 9781317230694

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Cell Biology by the Numbers by Ron Milo,Rob Phillips Pdf

A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid

Author : Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research
Publisher : National Academies Press
Page : 112 pages
File Size : 44,6 Mb
Release : 2002-01-25
Category : Science
ISBN : 9780309170420

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Stem Cells and the Future of Regenerative Medicine by Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research Pdf

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 40,5 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : Claude Desjardins,Larry L. Ewing
Publisher : Oxford University Press, USA
Page : 524 pages
File Size : 46,6 Mb
Release : 1993
Category : Medical
ISBN : 0195062698

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Cell and Molecular Biology of the Testis by Claude Desjardins,Larry L. Ewing Pdf

This book is a comprehensive, multi-authored work on the structure and function of the mammalian testis. The approach emphasizes gene expression, translation and production of specific gene products and the cellular and molecular regulation of these fundamental processes. Rather than provide a global survey of all aspects of male reproduction, this book stresses specific mechanisms that underscore the structure and function of the testis. It explains old and new concepts from a cellular and molecular perspective. This novel approach allows the authors to forge links between cell and molecular biology and well-established aspects of spermatogenesis and steroidogenesis. The result is a well-focused, comprehensive, and synthetic analysis of testicular biology.

Author : A. Strain,A.M. Diehl
Publisher : Springer Science & Business Media
Page : 681 pages
File Size : 45,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401149327

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Liver Growth and Repair by A. Strain,A.M. Diehl Pdf

Nelson Fausto The Greek myth of Prometheus with its picture of a vulture feasting on its chained victimhas traditionallyprovided a visualimageofliverregeneration. Itis apowerful and frightening representationbut ifone were to substitute the vulture by a surgeon and Prometheus by a patient laying on a properly prepared operating table, the outcomeoftheprocedurewould not differ significantlyfrom that describedbyGreek poets. Yet few of us who work in the field have stopped long enough to ask where this myth originated. Did the poet observe a case of liver regeneration in a human being? Was it brilliant intuition or perhaps, literally, just a 'gut feeling' of a poet looking for good rhymes that led to the prediction that livers grow when part of the tissueisremoved? Thisbookdoesnotattemptto solve these historical issues. Itdoes, instead, cover in detail some of the major modem themes of research on liver regen eration, injury and repair. As indicated in Dr. N. Bucher's chapter, the modem phase ofexperimental studies on liver regeneration started in 1931 with the publication by Higgins and Anderson of a method to perform a two-thirds resection of the liver of a rat. The technique described has 3 remarkable features: 1) it is highly reproducible, resulting in the removal of 68% of the liver, 2) it has minimal if any mortality, and 3) it consists only of blood vessel ligation and does not involve cutting through or wounding hepatic tissue.

Author : Eran Meshorer,Kathrin Plath
Publisher : Springer Science & Business Media
Page : 246 pages
File Size : 53,7 Mb
Release : 2011-01-11
Category : Science
ISBN : 9781441970374

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The Cell Biology of Stem Cells by Eran Meshorer,Kathrin Plath Pdf

Stem cells have been gaining a lot of attention in recent years. Their unique potential to self-renew and differentiate has turned them into an attractive model for the study of basic biological questions such as cell division, replication, transcription, cell fate decisions, and more. With embryonic stem (ES) cells that can generate each cell type in the mammalian body and adult stem cells that are able to give rise to the cells within a given lineage, basic questions at different developmental stages can be addressed. Importantly, both adult and embryonic stem cells provide an excellent tool for cell therapy, making stem cell research ever more pertinent to regenerative medicine. As the title The Cell Biology of Stem Cells suggests, our book deals with multiple aspects of stem cell biology, ranging from their basic molecular characteristics to the in vivo stem cell trafficking of adult stem cells and the adult stem-cell niche, and ends with a visit to regeneration and cell fate reprogramming. In the first chapter, “Early embryonic cell fate decisions in the mouse”, Amy Ralson and Yojiro Yamanaka describe the mechanisms that support early developmental decisions in the mouse pre-implantation embryo and the current understanding of the source of the most immature stem cell types, which includes ES cells, trophoblast stem (TS) cells and extraembryonic endoderm stem (XEN) cells.

Author : James Wilson
Publisher : Springer Science & Business Media
Page : 489 pages
File Size : 46,9 Mb
Release : 2013-03-09
Category : Science
ISBN : 9781461589334

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Mechanisms and Pathogenesis by James Wilson Pdf

Author : Jonathan Slack
Publisher : Oxford University Press
Page : 160 pages
File Size : 52,8 Mb
Release : 2021-09-23
Category : Science
ISBN : 9780192640390

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Stem Cells: A Very Short Introduction by Jonathan Slack Pdf

The topic of stem cells has a high profile in the media. We've made important advances in our scientific understanding, but despite this the clinical applications of stem cells are still in their infancy and most real stem cell therapy carried out today is some form of bone marrow transplantation. At the same time, a scandalous spread of unproven stem cell treatments by private clinics represents a serious problem, with treatments being offered which are backed by limited scientific rationale, and which are at best ineffective, and at worse harmful. This Very Short Introduction introduces stem cells, exploring what they are, and what scientists do with them. Introducing the different types of stem cells, Jonathan Slack explains how they can be used to treat diseases such as retinal degeneration, diabetes, Parkinson's disease, heart disease, and spinal trauma. He also discusses the important technique of bone marrow transplantation and some other types of current stem cell therapy, used for the treatment of blindness and of severe burns. Slack warns against fake stem cell treatments and discusses how to distinguish real from fake treatments. He also describes the latest scientific progress in the field, and looks forward to what we can expect to happen in the next few years Very Short Introductions: Brilliant, Sharp, Inspiring ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Author : Ivan Cameron
Publisher : Elsevier
Page : 452 pages
File Size : 54,8 Mb
Release : 1981-01-01
Category : Science
ISBN : 9780323162968

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The Transformed Cell by Ivan Cameron Pdf

The Transformed Cell deals with many of the differences that may exist between transformed cells and their normal counterparts. Topics covered range from malignancy and the cell surface to cell cycle regulation in normal and transformed cells; phenotypic expression of malignant transformation and its relationship to energy metabolism; and virus-induced transformation. The involvement of cyclic nucleotides in transformation is also discussed, together with intracellular pH and growth control in eukaryotic cells. This book is comprised of 12 chapters and begins with a brief description of terminology and basic concepts relating to cancer cells, as well as some comments on tumorigenicity and cell transformation. The next two chapters explore the evidence for and against the possible correlation of in vivo tumorigenicity to in vitro changes in the cytoskeletal system; anchorage-dependent growth; plasminogen activator production; agglutinability by lectins; and cell surface and plasma membrane properties. The regulation of cell proliferation and the relationships between ion movement and energy metabolism in normal and transformed cells are then examined, along with the transformation of normal cells by infection with new genetic material from tumor viruses. The remaining chapters focus on selected cellular properties that have been purported to differ between the normal and transformed cell, with particular reference to cyclic nucleotides; polyamine metabolism; cell viscosity; mobility of cellular water; intracellular pH; and element concentration. This monograph will be of interest to biologists and medical practitioners devoted to understanding cancer cell biology and cancer therapy.

Author : Feroze N. Ghadially
Publisher : Butterworth-Heinemann
Page : 778 pages
File Size : 47,6 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9781483192093

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Ultrastructural Pathology of the Cell and Matrix by Feroze N. Ghadially Pdf

Ultrastructural Pathology of the Cell and Matrix: Third Edition Volume 2 presents a comprehensive examination of the intracellular lesion. It discusses the analysis of pathological tissues using electron microscope. It addresses the experimental procedures made on the cellular level. Some of the topics covered in the book are the structure, distribution, and variations of rod-shaped microtubulated bodies; morphology of intracytoplasmic filaments; melanosome-producing and melanosome-containing cells in tumours; myofilaments in striated muscle; and pathological variations in size, shape, and numbers of microbodies. The intracytoplasmic and intranuclear annulate lamellae are fully covered. An in-depth account of the classification, history, and nomenclature of lysosomes are provided. The morphology and normal variations of melanosomes and anchoring fibrils are completely presented. A chapter is devoted to the endocytotic structures and cell processes. Another section focuses on the classification and nomenclature of fibrous components. The book can provide useful information to cytologists, pathologists, students, and researchers.

Author : Anonim
Publisher : Academic Press
Page : 412 pages
File Size : 49,8 Mb
Release : 1978-04-11
Category : Science
ISBN : 0080585876

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International Review of Cytology by Anonim Pdf

International Review of Cytology

Author : P.P. Rumyantsev
Publisher : Routledge
Page : 400 pages
File Size : 42,9 Mb
Release : 2017-09-19
Category : Medical
ISBN : 9781134338610

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Growth and Hyperplasia of Cardiac Muscle Cells by P.P. Rumyantsev Pdf

First Published in 1991. This Volume three of a set of a monograph series publishing versions of some of the research reviewed in its companion series, Section A (Cardiology Reviews) of Soviet Medical Reviews.

Author : Prasad S. Sunkara
Publisher : Elsevier
Page : 404 pages
File Size : 45,7 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9781483272177

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Novel Approaches to Cancer Chemotherapy by Prasad S. Sunkara Pdf

Novel Approaches to Cancer Chemotherapy compiles theories in tumor biology, emphasizing their potential use in developing therapeutic approaches to cancer therapy. This book emphasizes the unique property of a cancer cell and describes in detail how a novel therapeutic approach can be developed. This compilation consists of 11 chapters. Chapters 1, 2, 5, 6, and 7 deal with emerging areas of cancer therapy, such as the use of interferon, monoclonal antibodies, liposomes, lymphokines, and immunomodulators. The rest of the chapters cover some of the biochemical and enzyme targets in cancer cells, such as polyamines, prostaglandin, thromboxane, leukotrienes, 5a-reductase, aromatase, cell membrane glycoproteins, and sodium flux. The developments in relation to cancer therapy are mentioned in chapters dealing with biochemical approaches. This book is valuable to biologists, biochemists, immunologists, and molecular biologists intending to exploit the unique properties of cancer cells.