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Author : Charles W. Gehrke,Robert L. Wixom,Ernst Bayer
Publisher : Unknown
Page : 709 pages
File Size : 40,8 Mb
Release : 2001
Category : Chromatographic analysis
ISBN : 0444501142
Author : Anonim
Publisher : Elsevier
Page : 740 pages
File Size : 43,8 Mb
Release : 2001-12-18
Category : Science
ISBN : 0080476503
Chromatography - A Century of Discovery 1900-2000 represents the combined thinking and contributions of many chromatographers. It includes several in-depth feature chapters covering the Beginnings of Chromatography, which highlights M.S. Tswett, the inventor of chromatography, and several other early pioneers. Included are the contributions of several Nobel Laureates,and 125 Chromatography Award Winners and contributors, an extensive bibliography of publications on the History of the Evolution of Chromatography; a presentation of Major International Symposia supporting chromatography and as a bridge to selected sciences. Special chapters are written by well-known Chromatographers on Support and Stationary Phases, and Separations followed by a chapter on Milestones and Paradigm Shifts in Science. New discoveries in the life sciences and medicine, agriculture, the environment and separations technology in the 21st century will rely immeasurably on the 20th century research tools in chromatography and those yet to be developed.
Author : Robert L. Wixom,Charles W. Gehrke
Publisher : John Wiley & Sons
Page : 357 pages
File Size : 45,7 Mb
Release : 2011-01-31
Category : Science
ISBN : 9781118060292
Leading researchers discuss the past and present of chromatography More than one hundred years after Mikhail Tswett pioneered adsorption chromatography, his separation technique has developed into an important branch of scientific study. Providing a full portrait of the discipline, Chromatography: A Science of Discovery bridges the gap between early, twentieth-century chromatography and the cutting edge of today’s research. Featuring contributions from more than fifty award-winning chromatographers, Chromatography offers a multifaceted look at the development and maturation of this field into its current state, as well as its importance across various scientific endeavors. The coverage includes: Consideration of chromatography as a unified science rather than just a separation method Key breakthroughs, revolutions, and paradigm shifts in chromatography Profiles of Nobel laureates who used chromatography in their research, and the role it played Recent advances in column technology Chromatography’s contributions to the agricultural, space, biological/medical sciences; pharmaceutical science; and environmental, natural products, and chemical analysis Future trends in chromatography With numerous references and an engaging series of voices, Chromatography: A Science of Discovery offers a diverse look at an essential area of science. It is a unique and invaluable resource for researchers, students, and other interested readers who seek a broader understanding of this field.
Author : E. Heftmann
Publisher : Elsevier
Page : 584 pages
File Size : 45,9 Mb
Release : 2004-04-16
Category : Science
ISBN : 9780080472249
Chromatography has emerged as the most important and versatile analytical method. The book is not only an updated version of Heftmann's classical text, but it covers areas of future importance, such as microfluidics and computer resources. Under his experienced guidance, authorities in each field have contributed their practical experience to an integrated treatment of modern micro analysis. In Part A the theoretical basis of individual separation methods is explained and the technical aspects are illustrated. It includes the theory of gas and liquid chromatography as well as specific chromatographic techniques, such as size-exclusion, planar, ion, and affinity chromatography as well as various electrokinetic separation techniques. Microfluidics are covered for the first time and useful sources of analytical instruments are listed and evaluated. 1. Each chapter written by an authority 2. Thorough treatment of the theoretical basis of separation methods 3. Practical guide for performing analyses
Author : Dianna Borsi O'Brien
Publisher : Compass Flower Press
Page : 268 pages
File Size : 51,6 Mb
Release : 2017-04-26
Category : Biography & Autobiography
ISBN : 9781942168713
Charles W. Gehrke was unflinching. Determined. Persistent. He grew up among the poorest of the poor, yet carried only happy memories of those early years. Out of necessity he learned the value of hard work, as he and his brother helped support their family, even as children—but he never complained and never stopped working until his final days on this earth. He learned the importance of family, also at a tender age. They looked out for each other and stayed close all their lives, and Charles’s own family always came first, even as he rose to the top of his profession, recognized around the world for his pioneering scientific techniques and visionary thinking—modeling and promoting interdisciplinary collaboration and shared instrumentation long before those now commonplace tenets were on the radar of most scientists. He was chosen by NASA to examine lunar samples, searching for signs of life, and in the midst of it all, launched an entrepreneurial effort resulting in a company that grew and thrived for 40 years, employing more than 300 people. Dianna Borsi O’Brien has captured the essence of this man who achieved greatness, but in the end cared just as much about the people in his life as the things he’d accomplished. His story is inspiring, engaging, entertaining—and not to be missed.
Author : Michaela Wirth
Publisher : Springer Science & Business Media
Page : 61 pages
File Size : 41,8 Mb
Release : 2013-09-18
Category : Science
ISBN : 9783319006420
Lázlo Zechmeister was one of the pioneers in chromatology. He recognized the potential of the chromatographic method and made extensive use of it for his research about natural products. In 1938 he founded the book series "Progress in the Chemistry of Organic Natural Products" which includes review articles on contemporary research by masters in their fields of expertise. This text casts light on his life and his pioneering role in chromatography and provides more detailed insight on the book series.
Author : C. F. Poole
Publisher : Elsevier
Page : 952 pages
File Size : 49,8 Mb
Release : 2003
Category : Science
ISBN : 0444501991
The Essence of Chromatography presents a comprehensive survey of modern chromatography and is intended as a suitable text for graduate level courses in the separation sciences and as a self-study guide for professional chromatographers wishing to refresh their background in this rapidly expanding field.This title is an effective replacement for Chromatography Today, written by the same author with Salwa K. Poole, which is considered to be one of the definitive chromatographic texts of the last decade. Its format is modular, with extensive cross-references to permit rapid location of re.
Author : Katja Dettmer-Wilde,Werner Engewald
Publisher : Springer
Page : 902 pages
File Size : 55,8 Mb
Release : 2014-11-05
Category : Science
ISBN : 9783642546402
Gas chromatography continues to be one of the most widely used analytical techniques, since its applications today expand into fields such as biomarker research or metabolomics. This new practical textbook enables the reader to make full use of gas chromatography. Essential fundamentals and their implications for the practical work at the instrument are provided, as well as details on the instrumentation such as inlet systems, columns and detectors. Specialized techniques from all aspects of GC are introduced ranging from sample preparation, solvent-free injection techniques, and pyrolysis GC, to separation including fast GC and comprehensive GCxGC and finally detection, such as GC-MS and element-specific detection. Various fields of application such as enantiomer, food, flavor and fragrance analysis, physicochemical measurements, forensic toxicology, and clinical analysis are discussed as well as cutting-edge application in metabolomics is covered.
Author : John Swinley,Piet de Coning
Publisher : Elsevier
Page : 440 pages
File Size : 41,6 Mb
Release : 2019-06-28
Category : Science
ISBN : 9780128188897
A Practical Gas Analysis by Gas Chromatography provides a detailed overview of the most important aspects of gas analysis by gas chromatography (GC) for both the novice and expert. Authors John Swinley and Piet de Coning provide the necessary information on the selection of columns and components, thus allowing the reader to assemble custom gas analysis systems for specific needs. The book brings together a wide range of disparate literature on this technique that will fill a crucial gap for those who perform different types of research, including lab operators, separation scientists, graduate students and academic researchers. This highly practical, up-to-date reference can be consulted in the lab to guide key decisions about proper setup, hardware and software selection, calibration, analysis, and more, allowing researchers to avoid the common pitfalls caused by incorrect infrastructure. Shows, in detail, how valve configurations work, allowing readers to understand the building blocks of extremely complex systems Presents the complete infrastructure for setting up a gas analysis laboratory in a single source Includes a full chapter on practical analytical systems for analyzing various gas mixtures
Author : Gyorgy Marko-Varga,Peter Oroszlan
Publisher : Elsevier
Page : 294 pages
File Size : 43,8 Mb
Release : 2003-07-02
Category : Science
ISBN : 9780080530840
It is widely recognized that analytical technologies and techniques are playing a pioneering role in a range of today's foremost challenging scientific endeavours, including especially biological and biomedical research. Worthy of mention, for example, are the role that high performance separation techniques played in mapping the human genome and the pioneering work done within mass spectrometry. It is also apparent that state-of-the-art pharmaceutical and biomedical research is the major driving force of the development of new analytical techniques. Advancements in genomics research has provided the opportunity for a call for new drug targets for new technologies, which has speeded up drug discovery and helped to counteract the trend towards inflation of R&D costs. This book has been designed to be a reference covering a wide range of protein and genomic material analysis techniques. Emerging developments are presented with applications where relevant, and biological examples are included. It was developed to meet the ever growing need for a comprehensive and balanced text on an analytical technique which has generated a tremendous amount of interest in recent years. In addition, this book also serves as a modern textbook for advanced undergraduate and graduate courses in various disciplines including chemistry, biology and pharmacy. Authors of the individual chapters are recognized champions of their individual research disciplines and also represent contemporary major research centres in this field. · Contains state-of-the-art knowledge of the field and detailed descriptions of new technologies · Provides examples of relevant applications and case studies · Contributing authors are leading scientists in their own respective research fields
Author : Ibolya Molnár-Perl
Publisher : Elsevier
Page : 669 pages
File Size : 46,6 Mb
Release : 2005-06-27
Category : Science
ISBN : 9780080458458
Quantitation of Amino Acids and Amines by Chromatography: Methods and Protocols is intended to serve as a ready-to-use guide for the identification and quantification of amino acids and amines in various matrices, providing an overview on the theory and protocol of available methods. It presents chromatograms with exact elution programs enabling visual analysis and compares the advantages-disadvantages of various chromatographic techniques. In accordance with the chronological order of the development of chromatographic methods, different techniques are discussed: The possibilities of gas chromatography (GC), followed by those of the high performance liquid chromatography (HPLC) and the most recent techniques capillary electrophoresis (CE), capillary, electrochromatography (CEC). The characteristics of the given chromatographic procedure, relating to the topic in question, are classified according to the preliminary preparation/derivatization process(es), which means the simple methods, suitable for the analysis of the selected compound(s) in natural form, are followed by various derivatization proposals. Detailed protocols provide the reader with guidance in beginning tasks and on how to improve current methods. This book appeals to a wide audience and is recommended for those looking towards the wider reaches of identification and quantification of amino acids and amines. * Provides a systematic, and comprehensive summary of chromatographic techniques and derivatization processes * Compares advantages/disadvantages of various chromatographic techniques * Readers can undertake practical tasks using detailed protocols given in the book
Author : Gregory K. Webster
Publisher : CRC Press
Page : 420 pages
File Size : 55,5 Mb
Release : 2014-02-04
Category : Medical
ISBN : 9789814463003
Analytical chemists in the pharmaceutical industry are always looking for more-efficient techniques to meet the analytical challenges of today’s pharmaceutical industry. One technique that has made steady advances in pharmaceutical analysis is supercritical fluid chromatography (SFC). SFC is meeting the chromatography needs of the industry by providing efficient and selective testing capabilities on the analytical and preparative scale. The supercritical fluid mobile phase, consisting mainly of CO2, facilitates cost reduction costs and helps the industry in meeting green chemistry standards. This book provides a comprehensive overview of the use of SFC in pharmaceutical analysis. Supercritical Fluid Chromatography reviews the use of SFC in drug-discovery applications and describes its application in drug development. When a drug is developed and brought to market, it is tested many times for impurities and degradants, enantiomeric purity, and analytical and preparative isolations—it is tested during discovery and development and for under-regulated and unregulated methodologies. The book describes the use of SFC for each of these applications and discusses more in-depth topics, such as the use of SFC in mass spectrometric and polarographic detection. The book also sheds light on the role of SFC in drug development from natural products and the advancement of SFC with new technologies and its use in pilot-scale operations as a chromatographic technique.
Author : Yolanda Picó
Publisher : Academic Press
Page : 812 pages
File Size : 43,6 Mb
Release : 2012-09-01
Category : Science
ISBN : 9780123848635
Chemical Analysis of Food: Techniques and Applications reviews new technology and challenges in food analysis from multiple perspectives: a review of novel technologies being used in food analysis, an in-depth analysis of several specific approaches, and an examination of the most innovative applications and future trends. This book won a 2012 PROSE Award Honorable Mention in Chemistry and Physics from the Association of American Publishers. The book is structured in two parts: the first describes the role of the latest developments in analytical and bio-analytical techniques and the second reviews the most innovative applications and issues in food analysis. Each chapter is written by experts on the subject and is extensively referenced in order to serve as an effective resource for more detailed information. The techniques discussed range from the non-invasive and non-destructive, such as infrared spectroscopy and ultrasound, to emerging areas such as nanotechnology, biosensors and electronic noses and tongues. Important tools for problem-solving in chemical and biological analysis are discussed in detail. Winner of a PROSE Award 2012, Book: Honorable Mention in Physical Sciences and Mathematics - Chemistry and Physics from the American Association of Publishers Provides researchers with a single source for up-to-date information in food analysis Single go-to reference for emerging techniques and technologies Over 20 renowned international contributors Broad coverage of many important techniques makes this reference useful for a range of food scientists
Author : F. Svec,T.B. Tennikova,Z. Deyl
Publisher : Elsevier
Page : 800 pages
File Size : 41,8 Mb
Release : 2003-04-29
Category : Science
ISBN : 0080536972
During the past decade, monolithic materials in the shape of discs, stacked layers, rolled sheets, sponges, irregular chunks, tubes, and cylinders have all been successfully demonstrated. These formats were prepared from a wide variety of materials including natural polymers such as cellulose, synthetic polymers that involved porous styrene-, methacrylate-, and acrylamide-based polymers, and inorganic materials, mainly silica. Each approach is interesting from the point of view of both preparation and application. Although the current papers and patents concerned with monolithic separation media are quite numerous, the information is scattered throughout a vast number of journals. This book therefore fills the gap in the market for a comprehensive reference book on this subject. Monolithic materials concerns all of the current formats of monolithic materials and provides an integrated view of this novel format of separation media. Since the flow pattern in monolithic devices is different from that in packed beds, the hydrodynamics of the system and mass transport differ considerably from those derived for packed columns. Therefore, this book presents contributions concerned with both flow and mass transfer in the monolithic materials. A significant proportion of the book is devoted to the applications of monolithic materials. It also provides the reader with valuable information about the sources of the specific materials, their properties, and potential applications. · Monolithic materials are currently very popular within several scientific areas such as chromatography, optics, catalysis, diagnostics, genomics, proteomics, and microfluidics. · Provides valuable information about the sources of the specific materials, their properties, and potential applications. · Chapters written by leading experts in the area.
Author : Basanta Kumara Behera
Publisher : Elsevier
Page : 280 pages
File Size : 51,9 Mb
Release : 2023-08-01
Category : Science
ISBN : 9780443191589
Techniques for Downstream process for Biologic Drugs and Vaccines provides comprehensive technologies involved in processing postharvest broth to separate the target biological therapeutic products of extracellular or intercellular aspects in nature - to its highest purification form, and to thus make it acceptable to end users. The technologies involved in the post-harvesting of fermented broth are explained in this comprehensive resource in a simplified manner with different case studies to help non-engineering students and scientists easily capture the basic principle of biomass processing technologies and their applications in new projects related to the development and manufacturing of therapeutic bio-products. As conceptual development of biotechnology has taken new shape and style with the integration of medical sciences, physical science, and engineering, and has thus begun the need for the development of microbial or cell line process technology and application for large-scale isolation and purification of metabolites or vaccines through the fermentation process, this book covers the most important aspects. Provides insights into the conceptual strategic drive for manufacturing innovative biologically derived therapeutic compounds for commercial purposes Focuses on how to execute biopharmaceutical portfolio trends to bring sustainable manufacturing process as per guidelines of international regulatory acts Highlights emerging trends in medical sciences on tissue engineering, regenerative medicine, personalized medicines, and various innovative techniques on immunotherapy to fight against life-threatening diseases