Clinical Applications Of Nuclear Medicine Targeted Therapy

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Clinical Applications of Nuclear Medicine Targeted Therapy

Emilio Bombardieri,Ettore Seregni,Laura Evangelista,Carlo Chiesa,Arturo Chiti
Clinical Applications of Nuclear Medicine Targeted Therapy Book PDF

Author : Emilio Bombardieri,Ettore Seregni,Laura Evangelista,Carlo Chiesa,Arturo Chiti
Publisher : Springer
Page : 503 pages
File Size : 50,6 Mb
Release : 2018-03-27
Category : Medical
ISBN : 9783319630670

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Clinical Applications of Nuclear Medicine Targeted Therapy by Emilio Bombardieri,Ettore Seregni,Laura Evangelista,Carlo Chiesa,Arturo Chiti Pdf

This book offers a practical and modern update on radioisotope therapy. Clinically oriented, it provides a thorough guide to patient management, with the latest indications and procedures for the current radioisotopic treatments. It addresses the clinical problems associated with each respective pathology, discussing the management of patients (diagnosis and non-radioisotope therapy), the radiopharmaceuticals available today, and the current radioisotopic procedures. Wherever possible, information on dosimetry is included at the end of each topic, together with a list of and comments on the most recent guidelines with their recommendations for radiometabolic therapy. The book is divided into six main sections: thyroid diseases, hepatic tumors (HCC and hepatic metastases), bone metastases from prostate cancer, lymphomas, and neuroendocrine tumors. The last section is dedicated to new perspectives of radioisotope treatment. Based on contributions from of a multidisciplinary team of specialists: oncologists, surgeons, endocrinologists, hematologists, urologists, radiopharmacists and nuclear medicine physicians, it provides a comprehensive analysis of the position of radioisotope treatments among the various therapeutic options. Readers interested in targeted therapy, radiometabolic therapy, radioimmunotherapy and radiometabolic imaging will find this book both informative and insightful.

Nuclear Medicine Therapy

Cumali Aktolun,Stanley J. Goldsmith
Nuclear Medicine Therapy Book PDF

Author : Cumali Aktolun,Stanley J. Goldsmith
Publisher : Springer Science & Business Media
Page : 443 pages
File Size : 50,6 Mb
Release : 2012-08-31
Category : Medical
ISBN : 9781461440215

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Nuclear Medicine Therapy by Cumali Aktolun,Stanley J. Goldsmith Pdf

Nuclear Medicine Therapy presents the state of the art in targeted radionuclide therapy, both in clinical practice and contemporary clinical investigation and trials. With contributions from an internationally-distinguished group of physicians and scientists, the book is devoted entirely to the use of nuclear medicine techniques and technology for therapy of malignant and benign diseases. Individual chapters cover the scientific principles and clinical applications of radionuclide therapy and the state of clinical trials of agents currently under investigation in the therapy of tumors involving virtually every organ system. Due to overlapping interest in techniques, indications, and clinical use, the development of radionuclide therapy attracts considerable input from other medical specialists whose collaboration is essential, including radiation and medical oncologists, hematologists, diagnostic radiologists, hepatologists, endocrinologists, and rheumatologists. And because radionuclide therapy is a rapidly evolving field of nuclear medicine, it is the aim of this volume to appeal to all specialists involved in targeted radionuclide therapy and to contribute to the standardization of the practice globally.

Targeted Radionuclide Therapy

Tod W. Speer
Targeted Radionuclide Therapy Book PDF

Author : Tod W. Speer
Publisher : Lippincott Williams & Wilkins
Page : 564 pages
File Size : 40,9 Mb
Release : 2012-03-28
Category : Medical
ISBN : 9781451153262

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Targeted Radionuclide Therapy by Tod W. Speer Pdf

Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.

Advancing Nuclear Medicine Through Innovation

National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Nuclear and Radiation Studies Board,Committee on State of the Science of Nuclear Medicine
Advancing Nuclear Medicine Through Innovation Book PDF

Author : National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Nuclear and Radiation Studies Board,Committee on State of the Science of Nuclear Medicine
Publisher : National Academies Press
Page : 173 pages
File Size : 44,8 Mb
Release : 2007-09-11
Category : Medical
ISBN : 9780309134156

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Advancing Nuclear Medicine Through Innovation by National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Nuclear and Radiation Studies Board,Committee on State of the Science of Nuclear Medicine Pdf

Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

Nuclear Medicine in Oncology

Gang Huang
Nuclear Medicine in Oncology Book PDF

Author : Gang Huang
Publisher : Springer
Page : 346 pages
File Size : 52,5 Mb
Release : 2019-06-11
Category : Medical
ISBN : 9789811374586

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Nuclear Medicine in Oncology by Gang Huang Pdf

This book introduces molecular imaging and Target Therapy in various cancers. The first part is the subjects and primary focused on the basics of nuclear physics, radiation dosimetry, nuclear medicine equipment and small animal imaging equipment. The second part is about the radiopharmaceutical and commonly used clinical radiopharmaceuticals, including positron emission imaging agent, single photon emission imaging agent, and radionuclide therapy agents as well as their radioactive preparation, quality control, and a brief clinical application were included. Also, this part introduces a number of new imaging agents which were potential value of clinical applications. In the third part, the clinical application of the conventional imaging agent 18F-FDG in different tumors and neurodegenerative diseases and 18F-Dopa imaging in the nervous system are discussed. Besides the clinical applications of 99mTc labeled radiopharmaceuticals in parathyroid disease, coronary heart disease, myocardial infarction, sentinel lymph node, metastatic bone tumors, liver and gallbladder disease in children are introduced. Finally, the applications of radionuclide 131I on treatments of Graves' disease and differentiated thyroid cancer and metastases are investigated respectively. This book is a useful reference for professionals engaged in nuclear medicine and clinical research, including clinical nuclear medicine physicians, nuclear medicine engineers and nuclear medicine pharmacists.

Therapeutic Nuclear Medicine

Richard P. Baum
Therapeutic Nuclear Medicine Book PDF

Author : Richard P. Baum
Publisher : Springer
Page : 922 pages
File Size : 50,8 Mb
Release : 2014-08-16
Category : Medical
ISBN : 9783540367192

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Therapeutic Nuclear Medicine by Richard P. Baum Pdf

The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.

Nuclear Medicine in Oncology

Gang Huang
Nuclear Medicine in Oncology Book PDF

Author : Gang Huang
Publisher : Unknown
Page : 128 pages
File Size : 45,9 Mb
Release : 2019
Category : Cancer
ISBN : 9811374597

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Nuclear Medicine in Oncology by Gang Huang Pdf

This book introduces molecular imaging and Target Therapy in various cancers. The first part is the subjects and primary focused on the basics of nuclear physics, radiation dosimetry, nuclear medicine equipment and small animal imaging equipment. The second part is about the radiopharmaceutical and commonly used clinical radiopharmaceuticals, including positron emission imaging agent, single photon emission imaging agent, and radionuclide therapy agents as well as their radioactive preparation, quality control, and a brief clinical application were included. Also, this part introduces a number of new imaging agents which were potential value of clinical applications. In the third part, the clinical application of the conventional imaging agent 18F-FDG in different tumors and neurodegenerative diseases and 18F-Dopa imaging in the nervous system are discussed. Besides the clinical applications of 99mTc labeled radiopharmaceuticals in parathyroid disease, coronary heart disease, myocardial infarction, sentinel lymph node, metastatic bone tumors, liver and gallbladder disease in children are introduced. Finally, the applications of radionuclide 131I on treatments of Graves' disease and differentiated thyroid cancer and metastases are investigated respectively. This book is a useful reference for professionals engaged in nuclear medicine and clinical research, including clinical nuclear medicine physicians, nuclear medicine engineers and nuclear medicine pharmacists.

Nuclear Oncology

H. William Strauss,Giuliano Mariani,Duccio Volterrani,Steven M. Larson
Nuclear Oncology Book PDF

Author : H. William Strauss,Giuliano Mariani,Duccio Volterrani,Steven M. Larson
Publisher : Springer Science & Business Media
Page : 877 pages
File Size : 46,6 Mb
Release : 2012-11-27
Category : Medical
ISBN : 9780387488943

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Nuclear Oncology by H. William Strauss,Giuliano Mariani,Duccio Volterrani,Steven M. Larson Pdf

This book provides the reader with a comprehensive understanding of both the basic principles and the clinical applications of nuclear oncology imaging techniques. The authors have assembled a distinguished group of leaders in the field who provide valuable insight on the subject. The book also includes major chapters on the cancer patient and the pathophysiology of abnormal tissue, the evaluation of co-existing disease, and the diagnosis and therapy of specific tumors using functional imaging studies. Each chapter is heavily illustrated to assist the reader in understanding the clinical role of nuclear oncology in cancer disease therapy and management.

Molecular Imaging and Targeted Therapy

Shankar Vallabhajosula
Molecular Imaging and Targeted Therapy Book PDF

Author : Shankar Vallabhajosula
Publisher : Springer Nature
Page : 719 pages
File Size : 51,6 Mb
Release : 2023-03-31
Category : Medical
ISBN : 9783031232053

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Molecular Imaging and Targeted Therapy by Shankar Vallabhajosula Pdf

This book, now published in its second edition, covers a wide range of topics relating to the use of radiopharmaceuticals. The basics of nuclear chemistry, radiochemistry, and radiopharmacology are considered in detail, regulatory issues are reviewed, and potential applications in drug development, translational medicine, clinical diagnostics, and targeted therapy are discussed. Compared with the first edition, the chapters on targeted therapy with alpha- and beta-emitting radiopharmaceuticals and theranostics are completely new. Other chapters have been updated and revised as necessary. Radioisotope-based molecular imaging probes (radiopharmaceuticals) provide unprecedented insights into biochemistry and function in both normal and diseased states of living systems, with unbiased in vivo measurements of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology, including functional magnetic resonance imaging, can provide such high sensitivity and specificity at a tracer level. This book, written by an experienced radiochemist and scientist, offers valuable insights into the full range of applications of this technology.

Nuclear Oncology

Duccio Volterrani,Paola A. Erba,H. William Strauss,Giuliano Mariani,Steven M. Larson
Nuclear Oncology Book PDF

Author : Duccio Volterrani,Paola A. Erba,H. William Strauss,Giuliano Mariani,Steven M. Larson
Publisher : Springer Nature
Page : 2241 pages
File Size : 40,6 Mb
Release : 2022-10-04
Category : Medical
ISBN : 9783031054945

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Nuclear Oncology by Duccio Volterrani,Paola A. Erba,H. William Strauss,Giuliano Mariani,Steven M. Larson Pdf

This book discusses the role of nuclear medicine in the diagnosis, staging, and treatment of patients with specific cancers. It presents the incidence, pathophysiologic and clinical aspects of the disease, the use of nuclear imaging in diagnosis, staging requirements, management of specific tumors, and surveillance after primary treatment of cancers. It addresses the various diagnostic/therapeutic options that are currently available or are most likely to become available in the near future according to a prioritized approach, thereby keeping to a minimum the number of diagnostic imaging procedures the patient is expected to undergo. Topics include basic science, clinical applications, radionuclide therapy, radioguided surgery, heart disease in the cancer patient, and adverse effects of cancer therapy. Each clinical chapter discusses the radionuclide procedures within an integrated framework, thereby identifying the information required for effective treatment of specific tumors. The book concludes with a series of updated cases that define and expand the didactic material in the clinical application chapters. Thoroughly updated and revised, the third edition incorporates new clinical evidence validating the use of radionuclides for diagnosis and therapy in oncology, new radiotracers, and the growing integration of imaging modalities into different types of hybrid imaging. With contributions from a group of internationally distinguished practitioners, Nuclear Oncology: From Pathophysiology to Clinical Applications, Third Edition, is a valuable reference for nuclear medicine physicians, radiologists, medical and surgical oncologists, and other clinicians involved in the care and management of cancer patients.

Nuclear Medicine Textbook

Duccio Volterrani,Paola Anna Erba,Ignasi Carrió,H. William Strauss,Giuliano Mariani
Nuclear Medicine Textbook Book PDF

Author : Duccio Volterrani,Paola Anna Erba,Ignasi Carrió,H. William Strauss,Giuliano Mariani
Publisher : Springer
Page : 1331 pages
File Size : 47,9 Mb
Release : 2019-08-10
Category : Medical
ISBN : 9783319955643

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Nuclear Medicine Textbook by Duccio Volterrani,Paola Anna Erba,Ignasi Carrió,H. William Strauss,Giuliano Mariani Pdf

Building on the traditional concept of nuclear medicine, this textbook presents cutting-edge concepts of hybrid imaging and discusses the close interactions between nuclear medicine and other clinical specialties, in order to achieve the best possible outcomes for patients. Today the diagnostic applications of nuclear medicine are no longer stand-alone procedures, separate from other diagnostic imaging modalities. This is especially true for hybrid imaging guided interventional radiology or surgical procedures. Accordingly, today’s nuclear medicine specialists are actually specialists in multimodality imaging (in addition to their expertise in the diagnostic and therapeutic uses of radionuclides). This new role requires a new core curriculum for training nuclear medicine specialists. This textbook is designed to meet these new educational needs, and to prepare nuclear physicians and technologists for careers in this exciting specialty.

Radiopharmaceuticals for Therapy

F. F. (Russ) Knapp,Ashutosh Dash
Radiopharmaceuticals for Therapy Book PDF

Author : F. F. (Russ) Knapp,Ashutosh Dash
Publisher : Springer
Page : 347 pages
File Size : 46,8 Mb
Release : 2016-01-20
Category : Medical
ISBN : 9788132226079

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Radiopharmaceuticals for Therapy by F. F. (Russ) Knapp,Ashutosh Dash Pdf

This book provides detailed information on therapeutic radiopharmaceuticals and discusses emerging technologies which have potential for broad clinical implementation. Recent advances in molecular biology, radiopharmaceutical chemistry and radioisotope production have stimulated a new era for the use of radiopharmaceuticals for targeted radionuclide therapy (TRT). Emerging clinical trials include use of peptides and monoclonal antibodies radiolabeled with therapeutic radionuclides for cancer therapy. In addition, small molecules are used for the treatment of chronic diseases such as metastatic bone pain palliation and radiation synovectomy of inflammatory joints. In the interventional arena, therapy of primary and metastatic liver cancer and arterial restenosis following angioplasty of both the coronary and peripheral arteries are being explored. Reactor and accelerator production of therapeutic radioisotopes is also integrated into these discussions. The development and use of radiopharmaceutical targeting characteristics required for treatment of specific disease processes and how these are implemented for radiopharmaceutical design strategies are also described. Radiopharmaceuticals for Therapy will benefit audiences in nuclear medicine and radionuclide therapy and will thus prove an invaluable source of up-to-date information for students, radiopharmaceutical scientists and professionals working in the radiopharmacy and nuclear medicine specialties.

Handbook of Nuclear Medicine and Molecular Imaging

E. Edmund Kim
Handbook of Nuclear Medicine and Molecular Imaging Book PDF

Author : E. Edmund Kim
Publisher : World Scientific
Page : 473 pages
File Size : 46,7 Mb
Release : 2012
Category : Medical
ISBN : 9789814366236

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Handbook of Nuclear Medicine and Molecular Imaging by E. Edmund Kim Pdf

This handbook will provide updated information on nuclear medicine and molecular imaging techniques as well as its clinical applications, including radionuclide therapy, to trainees and practitioners of nuclear medicine, radiology and general medicine. Updated information on nuclear medicine and molecular imaging are vitally important and useful to both trainees and existing practitioners. Imaging techniques and agents are advancing and changing so rapidly that concise and pertinent information are absolutely necessary and helpful. It is hoped that this handbook will help readers be better equipped for the utilization of new imaging methods and treatments using radiopharmaceuticals.

Handbook of Radiopharmaceuticals

Michael J. Welch,Carol S. Redvanly
Handbook of Radiopharmaceuticals Book PDF

Author : Michael J. Welch,Carol S. Redvanly
Publisher : John Wiley & Sons
Page : 872 pages
File Size : 41,8 Mb
Release : 2003-01-17
Category : Medical
ISBN : 0471495603

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Handbook of Radiopharmaceuticals by Michael J. Welch,Carol S. Redvanly Pdf

A comprehensive, authoritative and up-to-date reference for the newcomer to radiopharmaceuticals and those already in the field. Radiopharmaceuticals are used to detect and characterise disease processes, or normal biological function, in living cells, animals or humans. Used as tracer molecules, they map the distribution, uptake and metabolism of the molecule in clinical studies, basic research or applied research. The area of radiopharmaceuticals is expanding rapidly. The number of PET centers in the world is increasing at 20% per year, and many drug companies are utilising PET and other forms of radiopharmaceutical imaging to evaluate products. * Readers will find coverage on a number of important topics such as radionuclide production, PET and drug development, and regulations * Explains how to use radiopharmaceuticals for the diagnosis and therapy of cancer and other diseases * The editors and a majority of the contributors are from the United States

Nuclear Medicine in Clinical Diagnosis and Treatment

Peter Josef Ell,Sanjiv Sam Gambhir
Nuclear Medicine in Clinical Diagnosis and Treatment Book PDF

Author : Peter Josef Ell,Sanjiv Sam Gambhir
Publisher : Unknown
Page : 1100 pages
File Size : 48,5 Mb
Release : 2004
Category : Nuclear medicine
ISBN : UOM:39015059182629

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Nuclear Medicine in Clinical Diagnosis and Treatment by Peter Josef Ell,Sanjiv Sam Gambhir Pdf

An internationally recognized team of editors and contributors present an authoritative, state-of-the-art reference on nuclear medicine and its clinical applications. They focus on helping the reader to solve the challenges encountered in day-to-day practice, including image interpretation, image optimization techniques, and pitfalls in image acquisition and interpretation. Over 4,400 illustrations, 803 in full color, comprise a comprehensive visual guide to interpretation. This new edition also incorporates three brand-new, full-color atlases-PET and PET/CT, SPECT and SPECT/CT, and a PET brain atlas-as well as many new full-color images (more than 800 in all) Completely revised and thoroughly updated throughout, the 3rd Edition encompasses of all of the latest advances in the diagnostic and therapeutic modalities available for cancer, heart disease, neurologic disorders, and trauma as well as other diseases, both common and rare.