Cns Regeneration

Author : Jeffrey Kordower,Mark H. Tuszynski
Publisher : Elsevier
Page : 526 pages
File Size : 50,5 Mb
Release : 2011-04-28
Category : Science
ISBN : 0080556981

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CNS Regeneration by Jeffrey Kordower,Mark H. Tuszynski Pdf

This second edition of CNS Regeneration updates the burgeoning field of regeneration in the Central Nervous System (CNS) from molecular, systems, and disease-based perspective. While the book covers numerous areas in detail, special emphasis is given to discussions of movement disorders such as Parkinson’s disease, Alzheimer’s disease, and spinal cord injury. Incorporates information gained from cutting-edge photomicroscopy techniques Includes current information on clinical trials Presents chapters on stem cells and other novel treatments for diseases of the CNS

Author : Mark H. Tuszynski,Jeffrey Kordower
Publisher : Elsevier
Page : 678 pages
File Size : 43,6 Mb
Release : 1998-10-27
Category : Science
ISBN : 0080529216

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CNS Regeneration by Mark H. Tuszynski,Jeffrey Kordower Pdf

CNS Regeneration focuses on some of the leading current neurological disease models and methods for promoting central nervous system regeneration. Editors and authors are experts in the field, with experience in basic as well as applied neuroscience. In a comprehensive, logical manner, the book unites important basic science advances in neuroscience with novel medical strategies. The first comprehensive, authoritative volume on the topic of CNS regeneration Reviews current therapeutic approaches Editors and authors are experts in the field Appeals to those interested in basic science as well as those concerned with its medical application

Author : Mark H. Tuszynski,Jeffrey Kordower
Publisher : Academic Press
Page : 720 pages
File Size : 49,9 Mb
Release : 1999
Category : Medical
ISBN : UOM:49015002788652

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CNS Regeneration by Mark H. Tuszynski,Jeffrey Kordower Pdf

CNS Regeneration focuses on some of the leading current neurological disease models and methods for promoting central nervous system regeneration. Editors and authors are experts in the field, with experience in basic as well as applied neuroscience. In a comprehensive, logical manner, the book unites important basic science advances in neuroscience with novel medical strategies. The first comprehensive, authoritative volume on the topic of CNS regeneration Reviews current therapeutic approaches Editors and authors are experts in the field Appeals to those interested in basic science as well as those concerned with its medical application

Author : António Salgado
Publisher : Elsevier
Page : 712 pages
File Size : 45,6 Mb
Release : 2020-06-10
Category : Medical
ISBN : 9780128180853

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Handbook of Innovations in Central Nervous System Regenerative Medicine by António Salgado Pdf

Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance Discusses the limitations of present therapies used in the clinics Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path

Author : Kwok Fai So,Xiao-Ming Xu
Publisher : Academic Press
Page : 444 pages
File Size : 54,7 Mb
Release : 2015-02-03
Category : Science
ISBN : 9780128018347

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Neural Regeneration by Kwok Fai So,Xiao-Ming Xu Pdf

Neural Regeneration provides an overview of cutting-edge knowledge on a broad spectrum of neural regeneration, including: Neural regeneration in lower vertebrates Neural regeneration in the peripheral nervous system Neural regeneration in the central nervous system Transplantation-mediated neural regeneration Clinical and translational research on neural regeneration The contributors to this book are experts in their fields and work at distinguished institutions in the United States, Canada, Australia, and China. Nervous system injuries, including peripheral nerve injuries, brain and spinal cord injuries, and stroke affect millions of people worldwide every year. As a result of this high incidence of neurological injuries, neural regeneration and repair is becoming a rapidly growing field dedicated to the new discoveries to promote structural and functional recoveries based on neural regeneration. The ultimate goal is to translate the most optimal regenerative strategies to treatments of human nervous system injuries. This valuable reference book is useful for students, postdoctors, and basic and clinical scientists who are interested in neural regeneration research. Provides an overview of cutting-edge knowledge on a broad spectrum of neural regeneration Highly translational and clinically-relevance International authors who are leaders in their respective fields Vivid art work making the chapters easily understood

Author : William M. Reichert
Publisher : CRC Press
Page : 296 pages
File Size : 49,6 Mb
Release : 2007-12-17
Category : Science
ISBN : 1420009303

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Indwelling Neural Implants by William M. Reichert Pdf

Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwelling Neural Implants: Strategies for Contending with the In Vivo Environment examines many of these challenges, paying particular attention to how the healing of tissues surrounding an implant can impact the intended use of a device. The contributions are divided into four sections · Part one examines wound healing from the initial insertion trauma through the inflammatory and repair process, explaining how the action of healing varies throughout different areas of the body. · Part two considers various performance issues specific to particular implant components, including those that arise from the chemical, mechanical, thermal, and electrical impact on surrounding tissues. It discusses challenges that result from chronic tissue stimulation and heat effects that occur with on-chip and telemetric processing. · Part three presents both in vitro and in vivo approaches to assessing wound healing response to materials. It includes the contribution of the developer of a chronic hollow fiber membrane implant who explains how an in vivo model is used to assess molecular transport in brain tissue surrounding the implant. · The final section evaluates molecular and materials strategies for intervening in CNS wound repair and enhancing the electrical communication between the electrode surface and the surrounding tissue. It also presents novel approaches to nerve regeneration and repair. This seminal work provides researchers with an up-to-date account of the progress in the field that they can build upon to bring us closer to realizing the full value of neural implants in combating otherwise intractable human health problems.

Author : Michael Selzer,Stephanie Clarke,Leonardo Cohen,Gert Kwakkel,Robert Miller
Publisher : Cambridge University Press
Page : 693 pages
File Size : 44,8 Mb
Release : 2014-04-24
Category : Medical
ISBN : 9781107011670

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Textbook of Neural Repair and Rehabilitation by Michael Selzer,Stephanie Clarke,Leonardo Cohen,Gert Kwakkel,Robert Miller Pdf

Volume 1 of the Textbook of Neural Repair and Rehabilitation covers the basic sciences relevant to recovery of function following injury to the nervous system.

Author : Norman Saunders,Katarzyna Dziegielewska
Publisher : CRC Press
Page : 354 pages
File Size : 52,5 Mb
Release : 2003-09-02
Category : Medical
ISBN : 9780203304488

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Degeneration and Regeneration in the Nervous System by Norman Saunders,Katarzyna Dziegielewska Pdf

Degeneration and Regeneration in the Nervous System brings together an international team of contributors to produce a series of critical reviews appraising key papers in the field. The pace of research on brain and spinal cord injury quickened considerably in the last ten years and there is much that is new and important that is covered in this book. However, there is still a long way to go before our knowledge will explain fully why the central nervous system has such a limited capacity for regeneration, and before experimental solutions can be applied to the patient. With emphasis on actual and therapeutic importance of the work reviewed, Degeneration and Regeneration in the Nervous System is a useful overview for graduate students, their teachers and researchers working in this field.

Author : William Frederick Windle
Publisher : Unknown
Page : 600 pages
File Size : 52,8 Mb
Release : 1955
Category : Brain
ISBN : UCAL:B4238102

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Regeneration in the Central Nervous System by William Frederick Windle Pdf

Author : Dorothy E. Oorschot,David G. Jones
Publisher : Springer Science & Business Media
Page : 121 pages
File Size : 51,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642751080

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Axonal Regeneration in the Mammalian Central Nervous System by Dorothy E. Oorschot,David G. Jones Pdf

This state-of-the-art review links the experimental data into a cohesive and critical account of CNS regeneration. Research findings are discussed in terms of their relevance to one (or more) of thirteen hypotheses concerned with regeneration in the mammalian CNS. Research findings reviewed include: regeneration in developing mammals and in submammalian vertebrates, the use of transplants and/or pharmacological treatments, in vitro studies on neurotrophic and neurite promoting factors and their potential relevance to CNS regeneration in vivo, and in vitro studies on the types of glial cells that may be responsible for enhancing or suppressing axonal re-growth.

Author : H.D. Perez,B. Mitrovic,A. Baron Van Evercooren
Publisher : Springer Science & Business Media
Page : 200 pages
File Size : 46,5 Mb
Release : 2007-01-19
Category : Medical
ISBN : 9783540276265

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Opportunities and Challenges of the Therapies Targeting CNS Regeneration by H.D. Perez,B. Mitrovic,A. Baron Van Evercooren Pdf

The therapeutic options for the treatment of Multiple Sclerosis (MS) and other neurodegenerative and traumatic diseases such as spinal cord injury, Alzheimer's, Parkinson's disease, etc. have experienced enormous progress over recent years. Despite these encouraging developments, available therapies are only partially effective, and the ultimate goal is still far from being attained. Improved understanding of the cellular and molecular mechanisms of the pathogenesis of neurodegeneration and demyelination has led to a variety of new therapeutic targets and approaches. In addition to modulation of the inflammatory process (MS) and classical neuroprotection (stroke, AD), therapeutic approaches focusing on active remyelinization and neuronal regeneration have become increasingly important. Based on current concepts, this book summarizes new therapeutic approaches.

Author : Shuxin Li,Junfang Wu,Andrea Tedeschi
Publisher : Frontiers Media SA
Page : 399 pages
File Size : 44,5 Mb
Release : 2022-03-09
Category : Science
ISBN : 9782889746330

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Advances in CNS Repair, Regeneration, and Neuroplasticity: From Basic Mechanisms to Therapeutic Strategies by Shuxin Li,Junfang Wu,Andrea Tedeschi Pdf

Author : Nicholas A Ingoglia,Marion Murray
Publisher : CRC Press
Page : 736 pages
File Size : 40,7 Mb
Release : 2000-09-29
Category : Medical
ISBN : 082470410X

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Axonal Regeneration in the Central Nervous System by Nicholas A Ingoglia,Marion Murray Pdf

Summarizing a review of research into factors that regulate, stimulate, and prevent regeneration in the central nervous system (CNS), this comprehensive reference progresses further into answering and resolving neuron capacity for axon regeneration in the mammalian CNS. Axonal Regeneration in the Central Nervous System analyzes axonal regeneration, reinnervation, and functional recovery in lower vertebrates examines the correlation between developmental age and the ability to regenerate considers mammalian neuron responses at the cell body, site of injury, and in the distal nerve, including apoptic cell death, and inflammatory and glial responses to injury reviews genomic responses to axotomy with a comparative description of transcribed genes from successfully regenerating neurons and neurons incapable of regrowth discusses how growing axons may induce the expression of genes in glia/Schwann cells following axotomy and regeneration describes the use of gene therapy to deliver trophic and survival factors to injured neurons explores the hospitable environments of the peripheral nerve, olfactory ensheathing cells, and fetal cell transplants for regeneration discusses results from applications of fetal CNS tissue to human spinal cord injuries and much more!

Author : Santiago Ramón y Cajal
Publisher : History of Neuroscience
Page : 977 pages
File Size : 50,7 Mb
Release : 1991
Category : Nervous system
ISBN : 9780195065169

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Cajal's Degeneration and Regeneration of the Nervous System by Santiago Ramón y Cajal Pdf

This book is a reprint of an English translation of Cajal's original work, with abundant notes and commentaries by the editor. This text describes Cajal's fundamental contributions to neuroscience, which continue to be important today. It accurately details Cajal's ideas and data, and providesreaders with the opportunity to learn what Cajal thought about his research career and the significance of his observations. Excerpts from Tello's memorial lectures also provide a contemporary view of Cajal's work.

Author : Hiroaki Naritomi,D. W. Krieger
Publisher : Karger Medical and Scientific Publishers
Page : 162 pages
File Size : 52,6 Mb
Release : 2013
Category : Medical
ISBN : 9783318023084

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Clinical Recovery from CNS Damage by Hiroaki Naritomi,D. W. Krieger Pdf

A compilation of innovative findings and new directions in neurological recovery After decades of focusing on how to alleviate and prevent recurrence of acute CNS injuries, the emphasis has finally shifted towards repairing such devastating events and rehabilitation. This development has been made possible by substantial progress in understanding the scientific underpinnings of recovery as well as by novel diagnostic tools, and most importantly, by emerging therapies awaiting clinical trials. In this publication, several international experts introduce novel areas of neurological reorganization and repair following CNS damage. Principles and methods to monitor and augment neuroplasticity are explored in depth and supplemented by a critical appraisal of neurological repair mechanisms and possibilities to curtail disability using computer or robotic interfaces. Rather than providing a textbook approach of CNS restoration, the editors selected topics where progress is most imminent in this labyrinthine domain of medicine. Moreover, the varied background and origins of the contributors lend this book a truly global perspective on the current state of affairs in neurological recovery.