Current Genetics In Dermatology

Author : Naoki Oiso
Publisher : BoD – Books on Demand
Page : 172 pages
File Size : 43,5 Mb
Release : 2013-02-06
Category : Medical
ISBN : 9789535109716

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Current Genetics in Dermatology by Naoki Oiso Pdf

This book presents current topics in genetics in the dermatologic field. Various skin disorders are inherited as mendelian inheritance. Genetic skin disorders are caused by mutations in the genes encoding proteins expressing in skin, skin appendages, melanocytes and immune-associated cells. Identification of genes and elucidation of function of the encoded proteins may provide novel strategies to overcome the disorders. We hope that this book offers sufficient current information in each disorder to scientists, physicians and dermatologists, and that novel therapies will be provided to affected individuals via these chapters.

Author : Yutaka Shimomura,Ken Natsuga,Daisuke Tsuruta,Tamihiro Kawakami
Publisher : Unknown
Page : 0 pages
File Size : 41,7 Mb
Release : 2022-08-10
Category : Electronic
ISBN : 1642701939

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Current Genetics in Dermatology by Yutaka Shimomura,Ken Natsuga,Daisuke Tsuruta,Tamihiro Kawakami Pdf

Author : Naoki Oiso
Publisher : IntechOpen
Page : 170 pages
File Size : 55,6 Mb
Release : 2013-02-06
Category : Medical
ISBN : 9535109715

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Current Genetics in Dermatology by Naoki Oiso Pdf

This book presents current topics in genetics in the dermatologic field. Various skin disorders are inherited as mendelian inheritance. Genetic skin disorders are caused by mutations in the genes encoding proteins expressing in skin, skin appendages, melanocytes and immune-associated cells. Identification of genes and elucidation of function of the encoded proteins may provide novel strategies to overcome the disorders. We hope that this book offers sufficient current information in each disorder to scientists, physicians and dermatologists, and that novel therapies will be provided to affected individuals via these chapters.

Author : Sherri J. Bale
Publisher : Remedica Pub Limited
Page : 230 pages
File Size : 45,6 Mb
Release : 2000-01-01
Category : Medical
ISBN : 1901346102

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Genetics for Dermatologists by Sherri J. Bale Pdf

During the past decade enormous progress has been made in our understanding of the molecular genetic basis of many dermatological disorders, and such information is already beginning to impact on clinical practice. This book provides dermatologists with a concise summary of what is presently known about the genetic basis of monogenic and polygenic dermatological disorders. Each disease is reviewed in an identical manner: clinical features, etc. The glossary provides a thorough grounding in the fundamentals of genetic terminology and techniques. Aimed primarily at dermatologists, this book also provides much of interest to clinical geneticists and genetic counsellors. With its quick reference format, Genetics for Dermatologists will be readily appreciated by busy practitioners.

Author : Brian J. Nickoloff,Frank O. Nestle
Publisher : Karger Medical and Scientific Publishers
Page : 391 pages
File Size : 53,8 Mb
Release : 2008-01-01
Category : Medical
ISBN : 9783805583916

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Dermatologic Immunity by Brian J. Nickoloff,Frank O. Nestle Pdf

Nickeloff (skin cancer research, Cardinal Bernardin Cancer Center, Chicago) and Nestle (cutaneous medicine and immunotherapy, King's College, London School of Medicine at Guy's, UK) assemble 19 review articles on autoimmune disease processes that affect the skin, covering both humoral and cellular immunity. The etiology, cellular and molecular mechanisms, therapeutic strategies, and pathophysiology of diseases such as psoriasis, dermatitis, cutaneous lupus erythematosus, vitiligo, and scleroderma are discussed by individuals in dermatology, genetics, immunology, and pathology who are based around the world. The book is aimed at clinical researchers, students, allergists, immunologists, dermatologists, and internists.

Author : Ethel Tur
Publisher : Karger Medical and Scientific Publishers
Page : 205 pages
File Size : 46,5 Mb
Release : 2007-01-01
Category : Medical
ISBN : 9783805583138

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Environmental Factors in Skin Diseases by Ethel Tur Pdf

Due to the increasing exposure of the skin to damaging environmental influences such as ultraviolet radiation, climatic determinants, chemicals or infections, research in this field is rapidly progressing. The interaction between the skin and the environment presents a fascinating and challenging research subject. For instance, skin aging and skin carcinogenesis are caused by both genetic and environmental factors. And also in diseases like psoriasis, atopic dermatitis and collagen diseases, genetic, immunologic and environmental factors interact. In recent years, new technologies to investigate skin response have allowed researchers to explore the interplay of environmental and genomic elements in skin cell biology, decipher the biochemical steps undertaken in the process, and study the genetics underlying variations in skin response to the environment. In this volume the state-of-the-art findings, ranging from molecular biology to epidemiology, are discussed thoroughly. The publication thus provides new insights for dermatologists, allergologists and immunologists who seek a better understanding of disease processes and new therapeutic strategies.

Author : Virginia P. Sybert
Publisher : Oxford University Press
Page : 489 pages
File Size : 53,7 Mb
Release : 2017
Category : Medical
ISBN : 9780190276478

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Genetic Skin Disorders by Virginia P. Sybert Pdf

This fully revised and updated edition of GENETIC SKIN DISORDERS reflects the most current understanding of the diagnosis, treatment, genetic basis, and differential diagnoses of inherited skin disorders. Organized with the needs of busy clinicians in mind, it offers detailed clinical guidance on the signs, symptoms, mode of inheritance, recurrence risk, and diagnosis of over 300 skin disorders, all in an accessible, at-a-glance format. Annotated bibliographies highlight the most relevant and up-to-date medical literature. Newly compiled lists of support groups, both national and international, for patients and their families supplement the ample resources for medical professionals. Informed by the author's extensive clinical experience and suffused with a distinctive, witty voice, GENETIC SKIN DISORDERS is an ideal companion in the laboratory, clinic, or consulting room. FEATURES · Includes both disease-based chapters and an appendix of skin signs that simplifies differential diagnosis for specialists and general practitioners alike · More than 800 color photographs illustrate the full spectrum of hair, skin, and nail abnormalities · Updated to reflect current classification of inherited skin disorders and the molecular underpinnings of these conditions

Author : Peter H. Hoeger,Veronica Kinsler,Albert C. Yan,Christine Bodemer,Margarita Larralde,David Luk,Vibhu Mendiratta,Diana Purvis
Publisher : John Wiley & Sons
Page : 0 pages
File Size : 49,6 Mb
Release : 2019-12-16
Category : Medical
ISBN : 9781119142195

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Harper's Textbook of Pediatric Dermatology, 2 Volume Set by Peter H. Hoeger,Veronica Kinsler,Albert C. Yan,Christine Bodemer,Margarita Larralde,David Luk,Vibhu Mendiratta,Diana Purvis Pdf

A consummate classic with a fresh approach to pediatric dermatology Children ́s skin is different. Maturation affects the epidermal barrier, the cutaneous microbiome, adnexal structures, vasculature, and transcutaneous absorption of drugs. The immature skin is more susceptible to pathogens and environmental disruption. Many genetic disorders are either present at birth or manifest early in childhood. Skin diseases thus present differently in children than in adults. Pediatric dermatology has seen significant advances over the last decade, particularly in the field of molecular genetics research, which has furthered our understanding of the pathogenesis of many skin diseases and the development of new approaches to treatment. This fourth edition of the Harper classic provides state-of-the-art information on all aspects of skin disease in children. It covers the diagnosis and treatment of all conditions - both common and rare - with a consistently evidence-based approach. Existing content has been refreshed and fully updated to reflect emerging thinking and to incorporate the latest in research and clinical data - especially at the genetic level. This new fourth edition includes: Greater focus on the genetics behind skin disease, including new genes/genodermatoses, progress in genetic analysis, and stem cell transplants Increased coverage of lasers and other technologies used to treat skin disease More summary tables, learning points, tables of differential diagnosis, and clinical algorithms for diagnosis and management Additional online features, including patient information links and multiple choice questions Harper's Textbook of Pediatric Dermatology delivers crucial clinical insights and up-to-date research information that spans the breadth of the field. As the most comprehensive reference book on this subject available, this revised fourth edition will support and guide the daily practice of both dermatologists and pediatricians across the world.

Author : Michael J. Murphy
Publisher : Springer Science & Business Media
Page : 480 pages
File Size : 48,8 Mb
Release : 2011-03-24
Category : Medical
ISBN : 9781607611714

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Molecular Diagnostics in Dermatology and Dermatopathology by Michael J. Murphy Pdf

Molecular Diagnostics in Dermatology and Dermatopathology presents the basics of molecular biology and molecular diagnostic methods most commonly used in the clinical laboratory, with an emphasis on the concepts and testing most relevant to dermatological diseases. Topics include the integration of newer diagnostic and prognostic techniques with ‘traditional’ histologic approaches, and discussions of regulatory, ethical, legal, economic issues and ‘newer’ technologies. This important diagnostic tool outlines the clinically relevant uses (i.e.; diagnostic, staging and/or prognostic) applications of these techniques in the field of dermatology. Molecular studies that investigate the pathogenesis of skin diseases will be excluded, unless they also have a direct diagnostic utility. The book will be of interest to practicing pathologists, dermatology and pathology residents, dermatologists, and dermatopathologists.

Author : Qianjin Lu,Christopher C. Chang,Bruce C. Richardson
Publisher : Academic Press
Page : 520 pages
File Size : 43,9 Mb
Release : 2015-02-16
Category : Science
ISBN : 9780128012727

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Epigenetics and Dermatology by Qianjin Lu,Christopher C. Chang,Bruce C. Richardson Pdf

Epigenetics and Dermatology explores the role of epigenetics in the pathogenesis of autoimmune-related skin diseases and skin cancer. Leading contributors cover common and uncommon skin conditions in which extensive epigenetic research has been done. They explain how environmental exposures (chemicals, drugs, sunlight, diet, stress, smoking, infection, etc.) in all stages of life (from a fetus in-utero to an elderly person) may result in epigenetic changes that lead to development of some skin diseases in life. They also discuss the possibilities of new and emergent epigenetic treatments which are gradually being adopted in management of various skin diseases. Chapters follow a conventional structure, covering fundamental biology of the disease condition, etiology and pathogenesis, diagnosis, commonly available treatments, and epigenetic therapy where applicable. Discusses the basic biology of skin diseases and skin cancers induced or aggravated by aberrant epigenetic changes Evaluates how to approach autoimmune-related skin diseases from a therapeutic perspective using the wealth of emergent epigenetic clinical trials Offers a coherent and structured table of contents with basic epigenetic biology followed by discussion of the spectrum of rheumatologic through neoplastic skin diseases, finally ending with a discourse on epigenetic therapy

Author : Anja K. Bosserhoff
Publisher : Springer
Page : 447 pages
File Size : 53,7 Mb
Release : 2017-01-20
Category : Medical
ISBN : 9783319413198

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Melanoma Development by Anja K. Bosserhoff Pdf

This book focuses on malignant melanoma, discussing the current state of scientific knowledge and providing insights into the underlying basic mechanisms, the molecular changes, genetics and genomics. Human Melanoma is a dangerous type of skin cancer affecting an increasing population, and a better understanding of its development will help in finding sophisticated targeted therapies. The second revised edition features the latest research findings and offers updates on the latest advances and potential novel melanoma therapies. It is a valuable resource for researchers and clinicians working in the fields of melanoma, cancer research and therapy as well as dermatology.

Author : Heiko Traupe
Publisher : Springer Science & Business Media
Page : 270 pages
File Size : 49,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642736506

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The Ichthyoses by Heiko Traupe Pdf

It is a great pleasure for me to see this work in print. As outlined by Dr. Traupe, at least 20 different types of ichthyosis have been identified to date. This book will effectively help to establish a correct diagnosis, as a basis for genetic counseling. Dr. Traupe proposes a new classification of the ichthyoses, based on reason able clinical criteria. He lets the reader share in his enormous knowledge and safely guides him through the difficult field of nomenclature. He describes the particular nature of these scaling disorders in a manner as simple as possible. During the last few years, research on ichthyosis has become a fascinating scientific challenge due to the introduction of novel investigative approaches. The main advantage of this book lies in the fact that the author successfully combines recent achievements made in lipid analysis, enzymology, electron microscopy, and molecular genetics. Heiko Traupe began his career in dermatology 11 years ago, as a resident in the Department of Dermatology in Munster. As we were both interested in the genetic aspects of skin diseases, this was the starting point of a most fruitful collaboration, which is still continuing. During our common work in Munster, Dr. Traupe was able, thanks to his unceasing clinical curiosity, to describe many novel aspects within the field of ichthyosis, and I took pride in coauthoring papers on new items such as cryptorchidism as a fea ture associated with X-linked recessive ichthyosis, autosomal dominant lamellar ichthyosis, and alopecia ichthyotica.

Author : Louanne Hudgins,Helga V. Toriello,Gregory M. Enns,H. Eugene Hoyme
Publisher : Oxford University Press
Page : 418 pages
File Size : 54,8 Mb
Release : 2014-05-30
Category : Medical
ISBN : 9780199388691

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Signs and Symptoms of Genetic Conditions by Louanne Hudgins,Helga V. Toriello,Gregory M. Enns,H. Eugene Hoyme Pdf

Connecting an abnormal physical exam to a possible genetic condition is a daunting and inexact task for any physician, be they a primary care provider, non-geneticist specialist, or fellowship-trained geneticist. Comprising 31 clinical protocols from the world's foremost clinical geneticists, Signs and Symptoms of Genetic Conditions provides a practical manual for the diagnosis and management of common human genetic conditions based on their presenting signs and/or symptoms. Each chapter examines a specific clinical finding and leads the user through a step-by-step approach to a differential diagnosis. To maximize clinical utility, this handbook features: · Prominent flow chart diagrams that graphically depict the diagnostic approach · Concise recommendations for laboratory and/or imaging studies · Health supervision and management strategies for the most common conditions associated with each presenting sign or symptom Whether for the student, resident, or seasoned clinician, Signs and Symptoms of Genetic Conditions will serve as a frontline resource for navigating differential diagnosis.

Author : Lynn B. Jorde
Publisher : Unknown
Page : 392 pages
File Size : 40,9 Mb
Release : 2006
Category : Genetic disorders
ISBN : UOM:39015063152527

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Medical Genetics by Lynn B. Jorde Pdf

'Medical Genetics' offers up-to-date information on modern genetics. This comprehensive study includes the latest findings from genetic research and how that knowledge can be used in clinical practice.

Author : Chiara Noli,Silvia Colombo
Publisher : Springer Nature
Page : 645 pages
File Size : 48,9 Mb
Release : 2020-06-15
Category : Medical
ISBN : 9783030298364

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Feline Dermatology by Chiara Noli,Silvia Colombo Pdf

This richly-illustrated handbook covers all aspects of modern feline dermatology, from the approach to different signs and symptoms to the description of the etiology, pathogenesis, clinical manifestation, diagnosis and current treatment of each feline dermatological disease. Thus this manual serves as essential practical guide to the busy practitioner to quickly and surely tackle cats with dermatological conditions, and offers a current and complete reference tool for the feline veterinarian and the veterinary dermatologist.