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Author : Victor Alexander Drill,Paul Lazar
Publisher : Toxicology-Sci
Page : 296 pages
File Size : 45,5 Mb
Release : 1984
Category : Contact dermatitis
ISBN : UCAL:B4526746
Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 50,7 Mb
Release : 1980
Category : Electronic
ISBN : OCLC:642095086
Author : Howard I. Maibach
Publisher : CRC Press
Page : 573 pages
File Size : 52,5 Mb
Release : 2001-03-15
Category : Medical
ISBN : 9781420022728
Toxic injury to the skin in the general population, and particularly in western populations, is on the increase. This is partly due to the expanding number of natural and man-made chemicals present in our everyday environment. The need for a thorough understanding of the skin, and the mechanisms of toxicity therein, has never been more pressing. Th
Author : Morris V. Shelanski,Karl L. Gabriel
Publisher : Unknown
Page : 24 pages
File Size : 48,5 Mb
Release : 1962
Category : Cleaning compounds
ISBN : IND:30000090361282
Ten Air Force development materials were studied via the prophetic patch test method on laboratory animals to determine the primary irritant effect, gross sensitization index, and gross percutaneous toxicity of these materials. The patch test studies with rabbits indicated that none of the materials was a primary irritant, sensitizer, nor gross systemic poison. Therefore, there was no contraindication to proceeding with a Shelanski repeated insult patch test on human volunteers. The results of the human patch test indicated that all of the materials were safe to use in contact with human skin.
Author : Morris V. Shelanski
Publisher : Unknown
Page : 16 pages
File Size : 43,8 Mb
Release : 1965
Category : Electronic
ISBN : IND:30000090378054
Author : Victor A. Drill
Publisher : Unknown
Page : 128 pages
File Size : 44,5 Mb
Release : 1977
Category : Electronic
ISBN : 0122220501
Author : Victor Alexander Drill,Paul Lazar
Publisher : Unknown
Page : 319 pages
File Size : 44,9 Mb
Release : 1980-01-01
Category : Dermatologie expérimentale - Congrès
ISBN : 0122220528
Author : Robert Chilcott,Shirley Price
Publisher : John Wiley & Sons
Page : 392 pages
File Size : 43,6 Mb
Release : 2008-07-31
Category : Science
ISBN : 9780470773086
Written by authorities in the field, this book provides a “bottom up” approach to studying skin toxicology. Principles and Practice of Skin Toxicology clearly outlines basic concepts, cites historical and modern references and contains a dictionary for easy reference. The inclusion of global legislation and regulatory aspects on the topic makes this a comprehensive review for every practitioner, clinical researcher in industry and academia, and MSc and PhD student of toxicology. Different sections cover skin structure and function, principles and measurement of skin absorption, clinical aspects of dermal toxicity and in vitro alternatives. A section on regulatory and legislative aspects includes case studies from the UK that fulfill European Union and US FDA requirements. A glossary provides definitions of technical terms, and the chapters contain an introduction, learning boxes and summary section for ease of use. Includes a chapter on drug delivery through the skin. Addresses risk assessment: a key area for the interpretation of skin absorption data that is rarely covered.
Author : Michael S. Roberts
Publisher : CRC Press
Page : 704 pages
File Size : 48,5 Mb
Release : 2007-12-14
Category : Medical
ISBN : 9780849375927
The source Dermal Absorption and Toxicity Assessment supplies a state-of-the-art overview of the dermal absorption process, and is divided into six well organized sections. Written by internationally recognized experts in the field, this Second Edition is a complete revised and updated text, covering the wide range of methods used to assess skin ab
Author : Hongbo Zhai,Howard I. Maibach
Publisher : CRC Press
Page : 1232 pages
File Size : 43,6 Mb
Release : 2004-02-25
Category : Medical
ISBN : 9780203426272
For twenty-five years, Dermatotoxicology has stood as the definitive reference book in the field. A generation of toxicologists and dermatologists has consulted this volume throughout their careers, finding within it a wealth of theoretical and practical guidance. Updated and expanded to reflect the latest developments in skin toxicology, De
Author : Nancy A. Monteiro-Riviere
Publisher : CRC Press
Page : 452 pages
File Size : 43,8 Mb
Release : 2010-02-17
Category : Medical
ISBN : 9781420079180
This key volume of the Target Organ Toxicology Series provides a fresh and modern approach to the subject of skin toxicology from the perspective of how the skin forms a barrier that protects the body from the external environment and how chemicals and drugs interact with the barrier properties of the skin. Any defects or perturbations to this barr
Author : Victor Alexander Drill,Paul Lazar
Publisher : Unknown
Page : 277 pages
File Size : 48,8 Mb
Release : 1977
Category : Dermatology, Experimental
ISBN : 0122220501
Author : Mario E. Lacouture
Publisher : John Wiley & Sons
Page : 764 pages
File Size : 51,6 Mb
Release : 2013-11-26
Category : Medical
ISBN : 9781118590607
The first book focusing specifically on frequent and frequently disabling side effects involving the skin, hair and nails in cancer patients According to the World Health Organization, there are approximately thirty million people living with a diagnosis of cancer – the majority of whom will receive surgery, systemic therapy, and/or radiation, and who will suffer from dermatologic adverse events. Dermatologists and oncologists are only beginning to grapple with these events, which pose serious quality-of-life issues with so many patients, and will become more prevalent as survival rates improve, thanks in part to new cancer treatments and drug regimens. Concentrating on a topic that has only been briefly touched upon by other texts, this book offers a focused perspective on the clinical presentation, underlying pathophysiologic mechanisms, and management of skin, hair, and nail conditions for oncologists, dermatologists, and allied practitioners. Dermatologic Principles and Practice in Oncology: Conditions of the Skin, Hair, and Nails in Cancer Patients: • Covers in detail the dermatologic adverse events of oncologic therapies, clinical presentations, and treatment recommendations • Enables dermatologists and other practitioners to significantly improve the care of patients with cancer • Addresses the dermatologic adverse events of cancer therapies used globally, of which a large number are found in developing countries • Emphasizes prophylactic measures – based on treatments used and type of cancer – to prevent the appearance of adverse events • Provides built-in discussions on patient education for practical counseling during therapies • Offers rapid-reference sections on topical dermatology drugs The first book to present dermatologic conditions in cancer patients and survivors in a uniform and in-depth manner, Dermatologic Principles and Practice in Oncology is ideal for oncologists, oncology nurses, and dermatologists who wish to take better care of those with adverse skin, hair, and nail conditions.
Author : Chantra Eskes,Erwin van Vliet,Howard I. Maibach
Publisher : Springer
Page : 592 pages
File Size : 45,5 Mb
Release : 2017-11-21
Category : Medical
ISBN : 9783319503530
This book provides comprehensive information on the alternative (non-animal) dermal toxicity test methods currently available for industrial, regulatory, and academic use and also explores potential future developments. It encompasses all areas of dermal toxicity, including skin irritation, skin corrosion, skin sensitization, UV-induced effects, and skin genotoxicity. An individual chapter is devoted to each test method, with coverage of the scientific basis, validation status and regulatory acceptance, applications and limitations, available protocols, and potential role within testing strategies. In addition, perspectives from the test developer are presented, for example regarding critical steps in the protocol. The closing section addresses areas that may be of relevance for the future of dermal toxicity safety testing, including the validation and regulatory acceptance of integrated testing strategies, novel complex skin models, and high-throughput screening techniques.
Author : Marcelo Larramendy,Sonia Soloneski
Publisher : BoD – Books on Demand
Page : 220 pages
File Size : 40,7 Mb
Release : 2016-10-26
Category : Medical
ISBN : 9789535127161
This edited book, Toxicology - New Aspects to This Scientific Conundrum, is intended to provide an overview on the different xenobiotics employed every day in our anthropogenic activities. We hope that this book will continue to meet the expectations and needs of all interested in the implications for the living species of known and new toxicants and to guide them in the future investigations.
