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Dermatotoxicology by Hongbo Zhai,Howard I. Maibach Pdf
For twenty-five years, Dermatotoxicology has stood as the definitive reference book in the field. A generation of toxicologists and dermatologists has consulted this volume throughout their careers, finding within it a wealth of theoretical and practical guidance. Updated and expanded to reflect the latest developments in skin toxicology, De
Dermatotoxicology by Klaus Peter Wilhelm,Hongbo Zhai,Howard I. Maibach Pdf
Reflecting the embryonic state of the field, the first edition of Dermatoxicology, published in 1977, numbered 567 pages. Now the foundational reference in dermal toxicology, this seventh edition consists of 1,032 pages and defines what was once a largely intuitive field but has evolved into an established science of metrics and mechanisms. Updated
DERMATOTOXICOLOGY 4ED by Francis Nicholas Marzulli,Howard I. Maibach Pdf
A guide to the field of dermatotoxicology. This edition includes fundamental information on the mechanisms of action of toxic substances on skin as well as practical information on the varied responses of skin to specific toxic substances and approaches to evaluating dermal toxicity. Other topics discussed include: hostile natural elements, such as ultraviolet radiation, poisonous plants, man-made detergents and chemicals; problems associated with chronic occupational skin exposure to toxic chemicals; animal alternative research programmes; carcinogenic and Photo Carcinogenic Potential Of Xenobiotic Chemicals; Oculotoxicity; Risk assessment and management; and cosmetic safety. Anatomical factors affecting barrier functions/ lipids of the permeability barrier/the skin immune system.
Dermatotoxicology Methods by Francis N. Marzulli,Howard I. Maibach Pdf
This work presents and evaluates methods employed to identify the potential of certain types of chemicals to adversely affect the skin. A variety of test methods are included such as tests for skin penetration, metabolism, irritation, the skin immune system, photo effects, skin cancer, and topical effects of retinoids and depigmenting chemicals. Tests for chemicals that affect the reproductive and nervous system are also included. Both animal and human tests that have been standardised and tests that are under development and employ animal alternatives are addressed in this book. Besides different testing methods, a rationale for accepting non-animal models and a review of some regulatory agency discussions about animal alternative tests are included.
DERMATOTOXICOLOGY 4ED by Francis Nicholas Marzulli,Howard I. Maibach Pdf
A guide to the field of dermatotoxicology. This edition includes fundamental information on the mechanisms of action of toxic substances on skin as well as practical information on the varied responses of skin to specific toxic substances and approaches to evaluating dermal toxicity. Other topics discussed include: hostile natural elements, such as ultraviolet radiation, poisonous plants, man-made detergents and chemicals; problems associated with chronic occupational skin exposure to toxic chemicals; animal alternative research programmes; carcinogenic and Photo Carcinogenic Potential Of Xenobiotic Chemicals; Oculotoxicity; Risk assessment and management; and cosmetic safety. Anatomical factors affecting barrier functions/ lipids of the permeability barrier/the skin immune system.
Dermatotoxicology Methods by Francis N. Marzulli,Howard I. Maibach Pdf
This work presents and evaluates methods employed to identify the potential of certain types of chemicals to adversely affect the skin. A variety of test methods are included such as tests for skin penetration, metabolism, irritation, the skin immune system, photo effects, skin cancer, and topical effects of retinoids and depigmenting chemicals. Tests for chemicals that affect the reproductive and nervous system are also included. Both animal and human tests that have been standardised and tests that are under development and employ animal alternatives are addressed in this book. Besides different testing methods, a rationale for accepting non-animal models and a review of some regulatory agency discussions about animal alternative tests are included.
Applied Dermatotoxicology by Howard I. Maibach,Golara Honari Pdf
Applied Dermatotoxicology: Clinical Aspects provides concise, systematic, and state-of-the-art information on the toxicological effects of substances on skin, and recent advances in dermal toxicity testing. This book specifically addresses the clinical presentations borne out of exposure to a variety of chemicals. It begins with an overview of skin biology to provide toxicologists with a basic understanding of its anatomy and physiology. Next it presents a variety of dermatotoxicological effects, as well at the toxic agents that cause them, with color photographs to illustrate these effects. Applied Dermatotoxicology: Clinical Aspects is an essential reference for toxicologists in industry, and for those medical professionals who encounter cases of dermal exposure to toxic agents. A concise, yet inclusive review of effects of chemical exposure Includes background on basic skin biology Provides vital clinical reference for toxicologists in non-clinical settings
Dermatotoxicology, Eighth Edition by Klaus Peter Wilhelm,Hongbo Zhai,Howard I. Maibach Pdf
The foundational reference in dermal toxicology, this classic text has been completely revised to bring it up to date in the new Eighth Edition, with almost a third of its chapters being newly added. The structure of the text has also been reorganized to enable easier location of a topic of interest. With contributions from leading international experts, this continues the tradition of providing unsurpassed theoretical and practical guidance for all those working on research aspects, on practical clinical issues, and on the regulatory aspects of exposure to toxic substances. This new edition contains updates to each chapter and contributions from leading international experts, provides an in-depth summary of research and regulatory applications related to dermal toxicology and pharmacology, presents many new chapters that describe the latest advances in dermatotoxicology, and addresses various levels of expertise regarding the development and use of dermal exposure data. New chapters include those on safety terminology, pharmacogenetics and dermatology, ethnic differences in skin properties, and the principles and practice of percutaneous absorption.
Dermatotoxicology, Sixth Edition by Hongbo Zhai,Howard I. Maibach Pdf
For twenty-five years, Dermatotoxicology has stood as the definitive reference book in the field. A generation of toxicologists and dermatologists has consulted this volume throughout their careers, finding within it a wealth of theoretical and practical guidance. Updated and expanded to reflect the latest developments in skin toxicology, Dermatotoxicology, Sixth Edition includes fundamental information on the mechanisms of action of toxic substances on the skin, as well as practical information on the various methods to evaluating dermal toxicity. It is unparalleled in its coverage, and this new edition broadens its scope to include chapters on: * Barrier Creams * Cosmetic Reactions * UV Radiation Exposure * Electron Paramagnetic Resonance * Powdered Human Stratum Corneum * Iontophoresis * Permeability of Skin for Metal Compounds * Current Trends in Skin Cancer Research * Tape Stripping Method v. Stratum Corneum * Hazardous Substances from Soil and Water * Isolated Perfused Porcine Skin Flap * Physiologically-based Pharmacokinetic Models This completely revised and reworked edition constitutes a major contribution to the field of dermatotoxicology. Presenting the most modern concepts and methods in use today, researchers and clinicians will find this an invaluable resource time and time again.
Dermatotoxicology Methods by Taylor & Francis Group Pdf
This work presents and evaluates methods employed to identify the potential of certain types of chemicals to adversely affect the skin. A variety of test methods are included such as tests for skin penetration, metabolism, irritation, the skin immune system, photo effects, skin cancer, and topical effects of retinoids and depigmenting chemicals. Tests for chemicals that affect the reproductive and nervous system are also included. Both animal and human tests that have been standardised and tests that are under development and employ animal alternatives are addressed in this book. Besides different testing methods, a rationale for accepting non-animal models and a review of some regulatory agency discussions about animal alternative tests are included.
Author : Francis Nicholas Marzulli,Howard I. Maibach Publisher : Taylor & Francis Group Page : 390 pages File Size : 51,7 Mb Release : 1998-01-01 Category : Dermatotoxicology ISBN : 1560326719
Dermatotoxicology Methods by Francis Nicholas Marzulli,Howard I. Maibach Pdf
This work presents and evaluates methods employed to identify the potential of certain types of chemicals to adversely affect the skin. A variety of test methods are included such as tests for skin penetration, metabolism, irritation, the skin immune system, photo effects, skin cancer, and topical effects of retinoids and depigmenting chemicals. Tests for chemicals that affect the reproductive and nervous system are also included. Both animal and human tests that have been standardised and tests that are under development and employ animal alternatives are addressed in this book. Besides different testing methods, a rationale for accepting non-animal models and a review of some regulatory agency discussions about animal alternative tests are included.
The differential application of skin protection in occupational settings becomes increasingly complex. Due to new scientific results and technological aspects as well as European and US regulations that have to be considered in the context of cosmetics and personal protective equipment, the practical application of skin protection requires constant reviewing and improvement. This publication provides a comprehensive update on specific cosmetic products from general principles of composition, protection from specific exposures, such as irritants, allergens and ultraviolet irradiation, to safety and efficacy testing both from the perspective of in vitro and in vivo testing. The second part focusses on special requirements and practical application in high-risk occupations and the respective skin protection programs, also including some critical remarks on the limitations of currently available skin protection measures. For specialists in the field of occupational dermatology such as dermatologists, allergists, occupational physicians, industrial hygienists, toxicologists, pharmacists and cosmetic scientists, this volume provides essential information on practical application, recommendation, testing or the making of personal skin protection products.
Dermatological and Transdermal Formulations by Kenneth A. Walters Pdf
Containing 350 illustrations, tables, and equations and covering AAPS/FDA guidelines for the experimentation and analysis of in vivo and in vitro percutaneous absorption, this reference provides comprehensive coverage of the development, preparation, and application of topical and transdermal therapeutic systems. Recognized international experts di
Advances in Environment Research and Application: 2011 Edition by Anonim Pdf
Advances in Environment Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Ecology Environment and Conservation. The editors have built Advances in Environment Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Ecology Environment and Conservation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Environment Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
