Diagnostic Meta Analysis

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Diagnostic Meta-Analysis

Giuseppe Biondi-Zoccai
Diagnostic Meta Analysis Book PDF

Author : Giuseppe Biondi-Zoccai
Publisher : Springer
Page : 319 pages
File Size : 50,6 Mb
Release : 2018-07-24
Category : Medical
ISBN : 9783319789668

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Diagnostic Meta-Analysis by Giuseppe Biondi-Zoccai Pdf

This book is the first exclusively devoted to the systematic synthesis of diagnostic test accuracy studies. It builds upon the major recent developments in reporting standards, search methods, and, in particular, statistical tools specifically devoted to diagnostic studies. In addition, it borrows extensively from the latest advances in systematic reviews and meta-analyses of intervention studies. After a section dedicated to methods for designing reviews, synthesizing evidence and appraising inconsistency in research, the application of these approaches is demonstrated in the context of case studies from various clinical disciplines. Diagnosis is central in medical decision-making, and in many other fields of human endeavor, such as education and psychology. The plurality of sources of evidence on diagnostic test accuracy poses a huge challenge for practitioners and researchers, as do the multiple dimensions of evidence validity, which include sensitivity, specificity, predictive values, and likelihood ratios. This book offers an invaluable resource for anyone aiming to improve decision-making processes in diagnosis, classification or risk prognostication, from epidemiologists to biostatisticians, radiologists, laboratory physicians and graduate students, as any physician interested in refining his methodological skills in clinical diagnosis.

Diagnostic Meta-Analysis

Giuseppe Biondi-Zoccai
Diagnostic Meta Analysis Book PDF

Author : Giuseppe Biondi-Zoccai
Publisher : Springer
Page : 0 pages
File Size : 45,9 Mb
Release : 2019-01-19
Category : Medical
ISBN : 3030076911

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Diagnostic Meta-Analysis by Giuseppe Biondi-Zoccai Pdf

This book is the first exclusively devoted to the systematic synthesis of diagnostic test accuracy studies. It builds upon the major recent developments in reporting standards, search methods, and, in particular, statistical tools specifically devoted to diagnostic studies. In addition, it borrows extensively from the latest advances in systematic reviews and meta-analyses of intervention studies. After a section dedicated to methods for designing reviews, synthesizing evidence and appraising inconsistency in research, the application of these approaches is demonstrated in the context of case studies from various clinical disciplines. Diagnosis is central in medical decision-making, and in many other fields of human endeavor, such as education and psychology. The plurality of sources of evidence on diagnostic test accuracy poses a huge challenge for practitioners and researchers, as do the multiple dimensions of evidence validity, which include sensitivity, specificity, predictive values, and likelihood ratios. This book offers an invaluable resource for anyone aiming to improve decision-making processes in diagnosis, classification or risk prognostication, from epidemiologists to biostatisticians, radiologists, laboratory physicians and graduate students, as any physician interested in refining his methodological skills in clinical diagnosis.

Diagnostic Meta-Analysis

Giuseppe Biondi-Zoccai
Diagnostic Meta Analysis Book PDF

Author : Giuseppe Biondi-Zoccai
Publisher : Springer
Page : 319 pages
File Size : 46,8 Mb
Release : 2018-08-25
Category : Medical
ISBN : 3319789651

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Diagnostic Meta-Analysis by Giuseppe Biondi-Zoccai Pdf

This book is the first exclusively devoted to the systematic synthesis of diagnostic test accuracy studies. It builds upon the major recent developments in reporting standards, search methods, and, in particular, statistical tools specifically devoted to diagnostic studies. In addition, it borrows extensively from the latest advances in systematic reviews and meta-analyses of intervention studies. After a section dedicated to methods for designing reviews, synthesizing evidence and appraising inconsistency in research, the application of these approaches is demonstrated in the context of case studies from various clinical disciplines. Diagnosis is central in medical decision-making, and in many other fields of human endeavor, such as education and psychology. The plurality of sources of evidence on diagnostic test accuracy poses a huge challenge for practitioners and researchers, as do the multiple dimensions of evidence validity, which include sensitivity, specificity, predictive values, and likelihood ratios. This book offers an invaluable resource for anyone aiming to improve decision-making processes in diagnosis, classification or risk prognostication, from epidemiologists to biostatisticians, radiologists, laboratory physicians and graduate students, as any physician interested in refining his methodological skills in clinical diagnosis.

Systematic Reviews in Health Care

Matthias Egger,George Davey-Smith,Douglas Altman
Systematic Reviews in Health Care Book PDF

Author : Matthias Egger,George Davey-Smith,Douglas Altman
Publisher : John Wiley & Sons
Page : 512 pages
File Size : 53,6 Mb
Release : 2008-04-15
Category : Medical
ISBN : 9780470693148

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Systematic Reviews in Health Care by Matthias Egger,George Davey-Smith,Douglas Altman Pdf

The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.

Doing Meta-Analysis with R

Mathias Harrer,Pim Cuijpers,Toshi A. Furukawa,David D. Ebert
Doing Meta Analysis with R Book PDF

Author : Mathias Harrer,Pim Cuijpers,Toshi A. Furukawa,David D. Ebert
Publisher : CRC Press
Page : 500 pages
File Size : 43,8 Mb
Release : 2021-09-15
Category : Mathematics
ISBN : 9781000435634

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Doing Meta-Analysis with R by Mathias Harrer,Pim Cuijpers,Toshi A. Furukawa,David D. Ebert Pdf

Doing Meta-Analysis with R: A Hands-On Guide serves as an accessible introduction on how meta-analyses can be conducted in R. Essential steps for meta-analysis are covered, including calculation and pooling of outcome measures, forest plots, heterogeneity diagnostics, subgroup analyses, meta-regression, methods to control for publication bias, risk of bias assessments and plotting tools. Advanced but highly relevant topics such as network meta-analysis, multi-three-level meta-analyses, Bayesian meta-analysis approaches and SEM meta-analysis are also covered. A companion R package, dmetar, is introduced at the beginning of the guide. It contains data sets and several helper functions for the meta and metafor package used in the guide. The programming and statistical background covered in the book are kept at a non-expert level, making the book widely accessible. Features • Contains two introductory chapters on how to set up an R environment and do basic imports/manipulations of meta-analysis data, including exercises • Describes statistical concepts clearly and concisely before applying them in R • Includes step-by-step guidance through the coding required to perform meta-analyses, and a companion R package for the book

Statistical Methods in Diagnostic Medicine

Xiao-Hua Zhou,Nancy A. Obuchowski,Donna K. McClish
Statistical Methods in Diagnostic Medicine Book PDF

Author : Xiao-Hua Zhou,Nancy A. Obuchowski,Donna K. McClish
Publisher : John Wiley & Sons
Page : 592 pages
File Size : 55,7 Mb
Release : 2014-08-21
Category : Medical
ISBN : 9781118626047

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Statistical Methods in Diagnostic Medicine by Xiao-Hua Zhou,Nancy A. Obuchowski,Donna K. McClish Pdf

Praise for the First Edition " . . . the book is a valuable addition to the literature in thefield, serving as a much-needed guide for both clinicians andadvanced students."—Zentralblatt MATH A new edition of the cutting-edge guide to diagnostic tests inmedical research In recent years, a considerable amount of research has focusedon evolving methods for designing and analyzing diagnostic accuracystudies. Statistical Methods in Diagnostic Medicine, Second Editioncontinues to provide a comprehensive approach to the topic, guidingreaders through the necessary practices for understanding thesestudies and generalizing the results to patient populations. Following a basic introduction to measuring test accuracy andstudy design, the authors successfully define various measures ofdiagnostic accuracy, describe strategies for designing diagnosticaccuracy studies, and present key statistical methods forestimating and comparing test accuracy. Topics new to the SecondEdition include: Methods for tests designed to detect and locate lesions Recommendations for covariate-adjustment Methods for estimating and comparing predictive values andsample size calculations Correcting techniques for verification and imperfect standardbiases Sample size calculation for multiple reader studies when pilotdata are available Updated meta-analysis methods, now incorporating randomeffects Three case studies thoroughly showcase some of the questions andstatistical issues that arise in diagnostic medicine, with allassociated data provided in detailed appendices. A related web sitefeatures Fortran, SAS®, and R software packages so thatreaders can conduct their own analyses. Statistical Methods in Diagnostic Medicine, Second Edition is anexcellent supplement for biostatistics courses at the graduatelevel. It also serves as a valuable reference for clinicians andresearchers working in the fields of medicine, epidemiology, andbiostatistics.

Network Meta-analysis

Giuseppe Biondi-Zoccai
Network Meta analysis Book PDF

Author : Giuseppe Biondi-Zoccai
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 48,8 Mb
Release : 2014
Category : Meta-analysis
ISBN : 1633210014

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Network Meta-analysis by Giuseppe Biondi-Zoccai Pdf

Network meta-analyses and mixed treatment comparisons represent the uppermost level in the evidence hierarchy for decision making, in medicine as well as in other scholarly fields. This book covers the main topics which should be mastered to critically read and interpret as well as, if deemed worthwhile, perform and report independently a network meta-analysis and mixed treatment comparison. The text includes dozens of tables and illustrations to guide visually the reader in understanding the basics as well as the more refined details of network meta-analyses.

Handbook of Meta-Analysis

Christopher H. Schmid,Theo Stijnen,Ian White
Handbook of Meta Analysis Book PDF

Author : Christopher H. Schmid,Theo Stijnen,Ian White
Publisher : CRC Press
Page : 570 pages
File Size : 50,8 Mb
Release : 2020-09-07
Category : Mathematics
ISBN : 9781498703994

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Handbook of Meta-Analysis by Christopher H. Schmid,Theo Stijnen,Ian White Pdf

1. Provides a comprehensive overview of meta-analysis methods and applications. 2. Divided into four major sub-topics, covering univariate meta-analysis, multivariate, applications and policy. 3. Designed to be suitable for graduate students and researchers new to the field. 4. Includes lots of real examples, with data and software code made available. 5. Chapters written by the leading researchers in the field.

Meta-Analysis with R

Guido Schwarzer,James R. Carpenter,Gerta Rücker
Meta Analysis with R Book PDF

Author : Guido Schwarzer,James R. Carpenter,Gerta Rücker
Publisher : Springer
Page : 252 pages
File Size : 40,7 Mb
Release : 2015-10-08
Category : Medical
ISBN : 9783319214160

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Meta-Analysis with R by Guido Schwarzer,James R. Carpenter,Gerta Rücker Pdf

This book provides a comprehensive introduction to performing meta-analysis using the statistical software R. It is intended for quantitative researchers and students in the medical and social sciences who wish to learn how to perform meta-analysis with R. As such, the book introduces the key concepts and models used in meta-analysis. It also includes chapters on the following advanced topics: publication bias and small study effects; missing data; multivariate meta-analysis, network meta-analysis; and meta-analysis of diagnostic studies.

Meta-Research

Evangelos Evangelou,Areti Angeliki Veroniki
Meta Research Book PDF

Author : Evangelos Evangelou,Areti Angeliki Veroniki
Publisher : Humana
Page : 0 pages
File Size : 52,5 Mb
Release : 2022-10-07
Category : Science
ISBN : 1071615688

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Meta-Research by Evangelos Evangelou,Areti Angeliki Veroniki Pdf

This volume presents state-of-the art design, analysis and integration approaches for biomedical data including novel statistical models for a comprehensive and powerful synthesis and assessment of scientific evidence. Chapters detail principles of systematic reviews, semi-automated tools for systematic searches, fixed- and random-effects meta-analytical models, living systematic reviews, meta-analysis of genetic studies, meta-analysis of pragmatic and explanatory trials, network meta-analysis, and other modern approaches for data synthesis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, the Meta- Research: Methods and Protocols book, written by global experts, will introduce the reader in a step-by-step process to the methods of the vital and highly promising field of evidence synthesis.

Publication Bias in Meta-Analysis

Hannah R. Rothstein,Alexander J. Sutton,Michael Borenstein
Publication Bias in Meta Analysis Book PDF

Author : Hannah R. Rothstein,Alexander J. Sutton,Michael Borenstein
Publisher : John Wiley & Sons
Page : 374 pages
File Size : 51,6 Mb
Release : 2006-02-03
Category : Mathematics
ISBN : 9780470870150

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Publication Bias in Meta-Analysis by Hannah R. Rothstein,Alexander J. Sutton,Michael Borenstein Pdf

Publication bias is the tendency to decide to publish a study based on the results of the study, rather than on the basis of its theoretical or methodological quality. It can arise from selective publication of favorable results, or of statistically significant results. This threatens the validity of conclusions drawn from reviews of published scientific research. Meta-analysis is now used in numerous scientific disciplines, summarizing quantitative evidence from multiple studies. If the literature being synthesised has been affected by publication bias, this in turn biases the meta-analytic results, potentially producing overstated conclusions. Publication Bias in Meta-Analysis examines the different types of publication bias, and presents the methods for estimating and reducing publication bias, or eliminating it altogether. Written by leading experts, adopting a practical and multidisciplinary approach. Provides comprehensive coverage of the topic including: Different types of publication bias, Mechanisms that may induce them, Empirical evidence for their existence, Statistical methods to address them, Ways in which they can be avoided. Features worked examples and common data sets throughout. Explains and compares all available software used for analysing and reducing publication bias. Accompanied by a website featuring software, data sets and further material. Publication Bias in Meta-Analysis adopts an inter-disciplinary approach and will make an excellent reference volume for any researchers and graduate students who conduct systematic reviews or meta-analyses. University and medical libraries, as well as pharmaceutical companies and government regulatory agencies, will also find this invaluable.

Cochrane Handbook for Systematic Reviews of Interventions

Julian P. T. Higgins,Sally Green
Cochrane Handbook for Systematic Reviews of Interventions Book PDF

Author : Julian P. T. Higgins,Sally Green
Publisher : Wiley
Page : 672 pages
File Size : 44,6 Mb
Release : 2008-11-24
Category : Medical
ISBN : 0470699515

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Cochrane Handbook for Systematic Reviews of Interventions by Julian P. T. Higgins,Sally Green Pdf

Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.

Synthesizing Evidence of Diagnostic Accuracy

Sarahlouise White,Tim Schultz,Yeetey Akpe Kwesi Enuameh
Synthesizing Evidence of Diagnostic Accuracy Book PDF

Author : Sarahlouise White,Tim Schultz,Yeetey Akpe Kwesi Enuameh
Publisher : Unknown
Page : 80 pages
File Size : 53,7 Mb
Release : 2011
Category : Diagnosis
ISBN : 1469800721

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Synthesizing Evidence of Diagnostic Accuracy by Sarahlouise White,Tim Schultz,Yeetey Akpe Kwesi Enuameh Pdf

Clinicians have long relied upon diagnostic tests for 'evidence' of the presence or absence of a disease or a condition. Similarly, policy makers must evaluate the value of a particular diagnostic test, compare it to any others, and decide which test should be made available or funded. Methods to synthesize evidence from diagnostic test accuracy studies are now emerging and this text examines the methodological basis to the synthesis of diagnostic test accuracy data and describes the processes involved in the conduct of a diagnostic test accuracy systematic review. Although screening studies share some similarities with diagnostic studies and may report similar statistics, screening is typically applied to uncover very early signs of disease or the risk of disease, whereas diagnostic tests are generally applied to individuals with signs or symptoms of disease. Issues of meta-analysis of screening studies are discussed elsewhere.

Principles and Practice of Systematic Reviews and Meta-Analysis

Sanjay Patole
Principles and Practice of Systematic Reviews and Meta Analysis Book PDF

Author : Sanjay Patole
Publisher : Springer Nature
Page : 189 pages
File Size : 49,6 Mb
Release : 2021-06-26
Category : Medical
ISBN : 9783030719210

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Principles and Practice of Systematic Reviews and Meta-Analysis by Sanjay Patole Pdf

Evidence based medicine is at the core of modern medicine. It involves the integration of individual clinical expertise with the best available clinical evidence from systematic research and patient's values and expectations. Systematic reviews offer a summary of the best available evidence. They are the most reliable and comprehensive statement about what works. Written by clinical academics from Australia, UK, USA, and Switzerland, this contributed volume introduces the readers to the principles and practice of systematic reviews and meta-analysis. It covers the various steps involved in systematic reviews including development of a focused question and the strategy for conducting a comprehensive literature search, identifying studies addressing the underlying question, assessment of heterogeneity and the risk of bias in the included studies, data extraction, and the approach to meta-analysis. Crucial issues such as selecting the model for meta-analysis, generating and interpreting forest plots, assessing the risk of publication bias, cautions in the interpretation of subgroup and sensitivity analyses, rating certainty of the evidence using GRADE guideline, and standardized reporting of meta-analysis (PRISMA) are covered in detail. Every attempt is made to keep the narrative simple and clear. Mathematical formulae are avoided as much as possible. While the focus of this book is on systematic reviews and meta-analyses of randomised controlled trials (RCTs), the gold standard of clinical research, the essentials of systematic reviews of non-RCTs, diagnostic test accuracy studies, animal studies, individual participant data meta-analysis, and network meta-analysis are also covered. Readers from all faculties of medicine will enjoy this comprehensive and reader friendly book to understand the principles and practice of systematic reviews and meta-analysis for guiding their clinical practice and research.

The Evidence Base of Clinical Diagnosis

J. Andre Knottnerus,Frank Buntinx
The Evidence Base of Clinical Diagnosis Book PDF

Author : J. Andre Knottnerus,Frank Buntinx
Publisher : BMJ Books
Page : 320 pages
File Size : 43,6 Mb
Release : 2009-01-26
Category : Medical
ISBN : 9781444300581

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The Evidence Base of Clinical Diagnosis by J. Andre Knottnerus,Frank Buntinx Pdf

This unique book presents a framework for the strategy and methodology of diagnostic research, in relation to its relevance for practice. Now in its second edition The Evidence Base of Clinical Diagnosis has been fully revised and extended with new chapters covering the STARD guidelines (STAndards for the Reporting of Diagnostic accuracy studies) and the multivariable analysis of diagnostic data. With contributions from leading international experts in evidence-based medicine, this book is an indispensable guide on how to conduct and interpret studies in clinical diagnosis. It will serve as a valuable resource for all investigators who want to embark on diagnostic research and for clinicians, practitioners and students who want to learn more about its principles and the relevant methodological options available.