Drug Actions

Author : Jae Y. Choe
Publisher : McGraw Hill Professional
Page : 770 pages
File Size : 45,5 Mb
Release : 2011-03-04
Category : Medical
ISBN : 9780071769457

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Drug Actions and Interactions by Jae Y. Choe Pdf

The quick reference guide you need to avoid harmful interactions between prescription drugs, over-the-counter medications, and dietary supplements Drug Actions and Interactions is a handy easy-to-access guide to understanding what major drugs are available for specific diseases, how selected drugs produce therapeutic benefits, side effects that may occur when taking these drugs, and which drugs and supplements should not be taken in combination with each other. Applying the 300 most often prescribed drugs in the United States to more than 80 common disorders, Drug Actions and Interactions discusses each drug’s mechanism of action, side effects, and drug interactions. Molecular structures of medications are also included to help you understand their mechanisms of action. Coverage includes drugs that act on the major systems (cardiovascular, respiratory, gastrointestinal, genitourinary, endocrine, neuronal); bone, muscle, skin, and joints; and general health. You will also find an appendix listing major drugs currently in use in each therapeutic classification. Thirty-two additional appendices detail interaction between a therapeutic group of drugs and an individual drug or group of drugs, such as interactions of beta-blockers, alpha-blockers, calcium-blockers, etc.

Author : Institute of Medicine,Division of Health Care Services,VA Pharmacy Formulary Analysis Committee
Publisher : National Academies Press
Page : 280 pages
File Size : 43,7 Mb
Release : 2000-10-03
Category : Medical
ISBN : 9780309183536

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Description and Analysis of the VA National Formulary by Institute of Medicine,Division of Health Care Services,VA Pharmacy Formulary Analysis Committee Pdf

The VA National Formulary generated controversy, which motivated congressional scrutiny and a directive to the VA to commission this report reviewing the experience with the National Formulary and formulary system. This Institute of Medicine committee was pleased to assist the Congress with this review, in part because the committee saw in the VHA example an opportunity to understand and anticipate problems that all publicly funded programs are likely to encounter in this new age of pharmaceuticals. The Congress asked the committee to review the restrictiveness of the National Formulary, its impact on the costs and quality of care in the VHA, and how it compared to formularies and drug management practices in the private sector and in other public programs, especially Medicaid. Detailed in the pages that follow, the committee's findings and conclusions on these questions are, the committee believes, highly instructive, though not always in the ways that we anticipated.

Author : Ruth R. Levine
Publisher : Unknown
Page : 440 pages
File Size : 52,6 Mb
Release : 1973
Category : Pharmacology
ISBN : UOM:39015000843824

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Pharmacology: Drug Actions and Reactions by Ruth R. Levine Pdf

Author : Mutschler,Hartmut Derendorf
Publisher : CRC Press
Page : 830 pages
File Size : 54,9 Mb
Release : 1995
Category : Medical
ISBN : 0849377749

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Drug Actions by Mutschler,Hartmut Derendorf Pdf

The most highly acclaimed pharmacology and toxicology text/reference used in Europe is now available in English. This excellent translation of Mutschler's Arzneimittelwirkungen combines a clear, informative narrative with 255 figures, 261 diagrams, and 198 tables to appeal to both new students and experts in pharmacy, pharmacology, and therapeutics. Drug structure and activity relationships are emphasized as an important dimension that is sometimes lacking in other pharmacology texts. Drug Actions is organized into three major sections covering general drug action and dosing principles, specific drug therapeutics, and toxicology. The first section provides an integrated overview of basic principles in pharmacology with chapters addressing pharmacokinetics, pharmacodynamics, drug side effects, drug interactions, chronopharmacology, rational and irrational drug combinations as well as drug developments and drug trials. The second section systematically describes specific drug actions with pharmacology, clinical indications, standard doses side effects, and contraindications described for each approved drug category. The third section addresses toxicology where specific drug toxicities are identified and treatment options for accidental and drug associated poisoning are presented. Topics covered include environmental, occupational, and nutritional exposure to toxins.

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 43,8 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : Maria A. Hernandez, Ph.D.,Appu Rathinavelu, Ph.D.
Publisher : CRC Press
Page : 404 pages
File Size : 41,9 Mb
Release : 2017-07-12
Category : Medical
ISBN : 9781351988650

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Basic Pharmacology by Maria A. Hernandez, Ph.D.,Appu Rathinavelu, Ph.D. Pdf

Intended for use in an introductory pharmacology course, Basic Pharmacology: Understanding Drug Actions and Reactions provides an in-depth discussion of how to apply the chemical and molecular pharmacology concepts, a discussion students need for more advanced study. The textbook introduces the principles of chemistry and biology necessary to understand drug interactions at the cellular level. The authors highlight chemical and physical properties of drugs, drug absorption and distribution, drug interactions with cellular receptors, and drug metabolism and elimination. The book begins with a review of chemical principles as they apply to drug molecules, focusing mainly on those for commonly prescribed drugs. The authors use drug structures to illustrate the chemical concepts learned in general and organic chemistry courses. They cover the dynamics of receptors in mediating the pharmacological effects of drugs. They clarify theories, drawn from the scientific literature, which explain drug-receptor interactions and the quantitative relationship between drug binding and its effects at the cellular level. The authors’ extensive use of drug structures for teaching chemical and molecular pharmacology principles, and their emphasis on the relevance of these principles in future professional life makes this book unique. It provides the framework for better understanding of advanced pharmacology and therapeutics topics. Blending medicinal chemistry and pharmacodynamics aspects, this textbook clearly elucidates the essential concepts that form the cornerstone for further work in pharmacology.

Author : Richard B. Silverman
Publisher : Elsevier
Page : 650 pages
File Size : 40,5 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780080513379

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The Organic Chemistry of Drug Design and Drug Action by Richard B. Silverman Pdf

Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

Author : Robert M. Julien, Ph.D.
Publisher : Holt Paperbacks
Page : 514 pages
File Size : 43,9 Mb
Release : 2013-08-06
Category : Health & Fitness
ISBN : 9781466851184

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A Primer of Drug Action by Robert M. Julien, Ph.D. Pdf

Since 1975, Robert Julien's A Primer of Drug Action has been the definitive guide to the effects of psychoactive drugs on the brain and on behavior. Now fully updated, this popular guide continues to lead the way through a rapidly changing field, providing readers with a clear, contemporary, and objective look at every drug and medication that either positively or adversely affects brain function. This edition includes important new information on: -Herbal medications -Drug therapy for behavioral and anxiety disorders -Clinical practice guidelines for treating psychological disorders -Depression and the action of antidepressant drugs -The use of newer anticonvulsants in the treatment of bipolar disorder, pain syndromes, and behavioral disorders -Drug therapy for children, adolescents and the elderly -"New generation" antipsychotic agents Authoritative, comprehensive, and suitable for those with little background in biology, A Primer of Drug Action is an indispensable source of information for anyone interested in drug use, abuse, and education.

Author : Francesco Clementi,Guido Fumagalli
Publisher : John Wiley & Sons
Page : 784 pages
File Size : 45,5 Mb
Release : 2015-07-01
Category : Medical
ISBN : 9781118768594

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General and Molecular Pharmacology by Francesco Clementi,Guido Fumagalli Pdf

With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use- without neglecting clinical application, toxicology and pharmacokinetics. • Covers cell and molecular pharmacology, bringing together current research on regulation of drug targets, at a level appropriate for advanced undergrad and graduate students • Discusses the relevance of pharmacokinetics and drug development for the clinical application of drugs • Presents material from the perspective of drug targets and interaction, the theoretical basis of drug action analysis, and drug properties • Focuses on structure-function relationships of drug targets – informing about their biochemical and physiologic functions and experimental and clinical pathways for drug discovery and development • Has a companion website that offers a host of resources: short additional chapters about methodology, topics at the forefront of research, and all figures and tables from the book

Author : T. J. Franklin,G. A. Snow
Publisher : Springer Science & Business Media
Page : 173 pages
File Size : 43,9 Mb
Release : 2013-11-21
Category : Medical
ISBN : 9781475745993

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Biochemistry and Molecular Biology of Antimicrobial Drug Action by T. J. Franklin,G. A. Snow Pdf

The subject is one of major interest in basic microbiology and infectious diseases and the book is a known classic.

Author : Vladimir Pliska,Bernard Testa,Han van de Waterbeemd
Publisher : John Wiley & Sons
Page : 463 pages
File Size : 42,9 Mb
Release : 2008-09-26
Category : Science
ISBN : 9783527614981

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Lipophilicity in Drug Action and Toxicology by Vladimir Pliska,Bernard Testa,Han van de Waterbeemd Pdf

In keeping with the outstanding importance of lipophilicity in biosciences, this volume examines all its facets in more than twenty contributions from leading experts. It offers a thorough and highly topical survey of this rapidly developing field of research. Color plates demonstrating structural aspects, a vast number of references, and the straightforward presentation of the material make this volume a invaluable tool for all researchers involved in drug design or in the investigation of drug action.

Author : Anonim
Publisher : Elsevier
Page : 342 pages
File Size : 54,8 Mb
Release : 2005-03-01
Category : Science
ISBN : 9780080456119

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Surface Activity in Drug Action by Anonim Pdf

Surface activity is present in living systems; for example in body fluid or cell soup and molecules of surface-active nature are crucial to living matter and its organization. Surface Activity in Drug Action proposes "a liquid membrane hypothesis of drug action" for surface-active drugs. Chapters 1-7 contains an account of the hypothesis and chapter 8 contains a general account of the application of surface activity in therapeutics. The methodology and presentation of the information makes Surface Activity in Drug Action valuable reading for students and researchers interested in surface activity. * Is clearly written * Includes contributions from prominent names in the field, such as Bhise and Subrahmanyam* Contains a general account of the application of surface activity in therapeutics

Author : Alex S. Evers,Mervyn Maze,Evan D. Kharasch
Publisher : Cambridge University Press
Page : 2902 pages
File Size : 45,6 Mb
Release : 2011-03-10
Category : Medical
ISBN : 9781139497022

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Anesthetic Pharmacology by Alex S. Evers,Mervyn Maze,Evan D. Kharasch Pdf

In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Author : Jennifer B. Dressman,Christos Reppas
Publisher : CRC Press
Page : 432 pages
File Size : 55,9 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781420077346

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Oral Drug Absorption by Jennifer B. Dressman,Christos Reppas Pdf

Oral Drug Absorption, Second Edition thoroughly examines the special equipment and methods used to test whether drugs are released adequately when administered orally. The contributors discuss methods for accurately establishing and validating in vitro/in vivo correlations for both MR and IR formulations, as well as alternative approaches for MR an

Author : J¿nos Fischer,David P. Rotella
Publisher : John Wiley & Sons
Page : 258 pages
File Size : 40,6 Mb
Release : 2015-05-04
Category : Medical
ISBN : 9783527336852

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Successful Drug Discovery, Volume 1 by J¿nos Fischer,David P. Rotella Pdf

The first volume of the book series "Successful Drug Discovery" is focusing on new drug discoveries during the last decade, from established drugs to recently introduced drugs of all kinds: small-molecule-, peptide-, and protein-based drugs. The role of serendipity is analyzed in some very successful drugs where the research targets of the lead molecule and the drug are different. Phenotypic and target-based drug discovery approaches are discussed from the viewpoint of pioneer drugs and analogues. This volume gives an excellent overview of insulin analogues including a discussion of the properties of rapid-acting and long-acting formulations of this important hormone. The major part of the book is devoted to case histories of new drug discoveries described by their key inventors. Eight case histories range across many therapeutic fields. The goal of this book series is to help the participants of the drug research community with a reference book series and to support teaching in medicinal chemistry with case histories and review articles of new drugs.