Environmental Endocrine Disruptors

Author : Rosario Pivonello,Evanthia Diamanti-Kandarakis
Publisher : Springer Nature
Page : 532 pages
File Size : 44,7 Mb
Release : 2023-04-20
Category : Medical
ISBN : 9783030390440

Get Book

Environmental Endocrinology and Endocrine Disruptors by Rosario Pivonello,Evanthia Diamanti-Kandarakis Pdf

This book describes how exposure to various classes of endocrine disruptors, as well as other environmental chemicals targeting the endocrine system by alternative non-endocrine mechanisms, impact on endocrinological and endocrinological-related diseases. It includes comprehensive reviews of all aspects of environmental endocrinology, ranging from sources and patterns of exposure and identification of endocrine targets to direct endocrine disruptive mechanisms and indirect actions on the endocrine system, the latter including endocrine cell-directed cytotoxicity, oxidative damage, and genetic and epigenetic aberrations resulting in endocrine damage. It also examines the causal pathways and offers an extensive overview of downstream endocrinological and endocrinological-related disorders. In addition, several chapters focus on transgenerational actions, which are a topic of particular interest. Lastly, evidence from preclinical and clinical studies provides the basis for an in-depth, critical discussion of each topic. The book is part of the SpringerReference program, which provides access to ‘living editions’ that are constantly updated using a dynamic peer-review publishing process.

Author : A Crain,L J GuilletteJr
Publisher : CRC Press
Page : 432 pages
File Size : 44,6 Mb
Release : 2000-08-17
Category : Medical
ISBN : 9781135466008

Get Book

Environmental Endocrine Disruptors by A Crain,L J GuilletteJr Pdf

Addresses many aspects of endocrine disruption by environmental encountered toxic substances. Initial chapters provide essential background information whilst later chapters address specific aspects of endocrine disrupting contaminants (EDC)

Author : Lawrence H. Keith
Publisher : Wiley-Interscience
Page : 0 pages
File Size : 51,6 Mb
Release : 1997-12-24
Category : Science
ISBN : 0471241148

Get Book

Environmental Endocrine Disruptors by Lawrence H. Keith Pdf

This database, available in print and electronic form, provides information on chemical, physical, and toxicological properties of known and suspected environmental endocrine disruptors in a convenient easy-to-use format. Much of the research on EEDs has focused on the effects of these chemicals on wildlife, linking certain compounds to birth defects and abnormal development of immune and reproductive systems.

Author : Sushil K. Khetan
Publisher : John Wiley & Sons
Page : 408 pages
File Size : 49,7 Mb
Release : 2014-05-23
Category : Technology & Engineering
ISBN : 9781118891155

Get Book

Endocrine Disruptors in the Environment by Sushil K. Khetan Pdf

Endocrine Disruptors in the Environment A concise and engaging overview of endocrine disruption phenomena that brings complex concepts within the reach of non-specialists For most of the last decade, the science of endocrine disruption has evolved with more definitive evidence of its damaging potential to health and environment. This book lists the major environmental chemicals of concern and their mechanism of endocrine disruption including remedial measures for them. Divided into three parts, Endocrine Disruptors in the Environment begins with an overview of the endocrine system and endocrine disruptors, discussing their salient features and presenting a historical perspective of endocrine disruption phenomena. It then goes on to cover hormone- signaling mechanisms, followed by various broad classes of putative endocrine disruptors, before introducing readers to environmental epigenetic modifications. Part two of the book focuses on removal processes of various EDCs by biotic and abiotic transformation/degradation. The last section consists of four chapters embracing themes on finding solutions to environmental EDCs—including their detection, regulation, replacement, and remediation. Endocrine Disruptors in the Environment is the first book to detail the endocrine effects of several known environmental contaminants and their mechanism of endocrine disruption. Additionally, it: Covers both the chemistry and biology of endocrine disruption and compiles almost all the known endocrine disrupting environmental chemicals and their mechanisms of toxicity Addresses policy and regulatory issues relevant to EDCs including scientific uncertainty and precautionary policy Brings forth the use of Green Chemistry principles in avoiding endocrine disruption in the designing and screening for safer chemicals and remediation of the EDCs in aquatic environment Includes a useful glossary of technical terms, a list of acronyms, topical references, and a subject index Endocrine Disruptors in the Environment is an ideal book for environmental chemists and endocrine toxicologists, developmental biologists, endocrinologists, epidemiologists, environmental health scientists and advocates, and regulatory officials tasked with risk assessment in environment and health areas.

Author : Sushil K. Khetan
Publisher : John Wiley & Sons
Page : 410 pages
File Size : 55,6 Mb
Release : 2014-06-23
Category : Technology & Engineering
ISBN : 9781118852934

Get Book

Endocrine Disruptors in the Environment by Sushil K. Khetan Pdf

Endocrine Disruptors in the Environment A concise and engaging overview of endocrine disruption phenomena that brings complex concepts within the reach of non-specialists For most of the last decade, the science of endocrine disruption has evolved with more definitive evidence of its damaging potential to health and environment. This book lists the major environmental chemicals of concern and their mechanism of endocrine disruption including remedial measures for them. Divided into three parts, Endocrine Disruptors in the Environment begins with an overview of the endocrine system and endocrine disruptors, discussing their salient features and presenting a historical perspective of endocrine disruption phenomena. It then goes on to cover hormone- signaling mechanisms, followed by various broad classes of putative endocrine disruptors, before introducing readers to environmental epigenetic modifications. Part two of the book focuses on removal processes of various EDCs by biotic and abiotic transformation/degradation. The last section consists of four chapters embracing themes on finding solutions to environmental EDCs—including their detection, regulation, replacement, and remediation. Endocrine Disruptors in the Environment is the first book to detail the endocrine effects of several known environmental contaminants and their mechanism of endocrine disruption. Additionally, it: Covers both the chemistry and biology of endocrine disruption and compiles almost all the known endocrine disrupting environmental chemicals and their mechanisms of toxicity Addresses policy and regulatory issues relevant to EDCs including scientific uncertainty and precautionary policy Brings forth the use of Green Chemistry principles in avoiding endocrine disruption in the designing and screening for safer chemicals and remediation of the EDCs in aquatic environment Includes a useful glossary of technical terms, a list of acronyms, topical references, and a subject index Endocrine Disruptors in the Environment is an ideal book for environmental chemists and endocrine toxicologists, developmental biologists, endocrinologists, epidemiologists, environmental health scientists and advocates, and regulatory officials tasked with risk assessment in environment and health areas.

Author : I. Assenmacher,D.S. Farner
Publisher : Springer Science & Business Media
Page : 344 pages
File Size : 43,5 Mb
Release : 2013-03-07
Category : Medical
ISBN : 9783642669811

Get Book

Environmental Endocrinology by I. Assenmacher,D.S. Farner Pdf

From 11 to 15 July 1977 about 60 physiologists, endo crinologists, ecologists and other biologists from 14 countries convened at the University Montpellier for a symposium on Environmental Endocrinology. This meet ing was organized as a Satellite Symposium of the 27th International Congress of Physiological Sciences, Paris, 18-23 July 1977. This volume is a record of the com munications presented at the symposium. The objectives of the program were to examine the role of the endocrine system in a wide spectrum of adjustments and adaptations to changes in environmental conditions by various spe cies of animals, including man, and to promote an ex change of ideas among investigators who have approached these functions from diverse aspects. The diversity of the information and ideas communicated is great. Of necessity, they represent only an extremely modest se lection of the many facets of endocrine function in the interaction of animals with their environments. Be yond the usefulness of the communications individually, we hope that they collectively demonstrate the substan tial heuristic value of the concept of environmental endocrinology as it was perceived by the participants. We acknowledge gratefully the kindness and sympathy of Professor Jaques ROUZAUD, President of the University of Montpellier II, for his generous extension of the hospitality of the University to the Symposium. We are most grateful to Mrs. Monique VIEU who effected so well the secretarial organization of the Sympos.

Author : National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Hormonally Active Agents in the Environment
Publisher : National Academies Press
Page : 453 pages
File Size : 52,5 Mb
Release : 2000-02-03
Category : Science
ISBN : 9780309064194

Get Book

Hormonally Active Agents in the Environment by National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Hormonally Active Agents in the Environment Pdf

Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.

Author : Marcelo Larramendy,Sonia Soloneski
Publisher : BoD – Books on Demand
Page : 280 pages
File Size : 46,5 Mb
Release : 2016-06-16
Category : Science
ISBN : 9789535124016

Get Book

Environmental Health Risk by Marcelo Larramendy,Sonia Soloneski Pdf

This book, Environmental Health Risk - Hazardous Factors to Living Species, is intended to provide a set of practical discussions and relevant tools for making risky decisions that require actions to reduce environmental health risk against environmental factors that may adversely impact human health or ecological balances. We aimed to compile information from diverse sources into a single volume to give some real examples extending concepts of those hazardous factors to living species that may stimulate new research ideas and trends in the relevant fields.

Author : Lawrence H. Keith,Tammy L. Jones-Lepp,Larry L. Needham
Publisher : Unknown
Page : 188 pages
File Size : 41,6 Mb
Release : 1999
Category : MEDICAL
ISBN : 084121753X

Get Book

Analysis of Environmental Endocrine Disruptors by Lawrence H. Keith,Tammy L. Jones-Lepp,Larry L. Needham Pdf

Author : Alexandra Fucic,Alberto Mantovani
Publisher : Royal Society of Chemistry
Page : 539 pages
File Size : 48,7 Mb
Release : 2020-12-08
Category : Science
ISBN : 9781788017411

Get Book

Challenges in Endocrine Disruptor Toxicology and Risk Assessment by Alexandra Fucic,Alberto Mantovani Pdf

Insight into the role of hormones, particularly estrogen and testosterone, in health and disease etiology - including interactions with other hormone pathways - has dramatically changed. Estrogen and androgen receptors, with their polymorphisms, are key molecules in all tissues and are involved in a number of homeostatic mechanisms but also pathological processes including carcinogenesis and the development of metabolic and neurological disorders such as diabetes and Alzheimer's disease. Endocrine disrupting chemicals (EDCs) can interfere with the endocrine (hormone) systems at certain dosages and play a key role in the pathology of disease. Most known EDCs are manmade and are therefore an increasing concern given the number commonly found in household products and the environment. This book will cover the mechanisms of EDC pathology across the spectrum of disease, as well as risk assessment and government and legal regulation to provide a holistic view of the current issues and cutting-edge research in the topic. With contributions from global leaders in the field, this book will be an ideal reference for toxicologists, endocrinologists and researchers interested in developmental biology, regulatory toxicology and the interface between environment and human health.

Author : Gretchen Neigh,Megan Mitzelfelt
Publisher : Academic Press
Page : 236 pages
File Size : 44,6 Mb
Release : 2016-05-10
Category : Medical
ISBN : 9780128026083

Get Book

Sex Differences in Physiology by Gretchen Neigh,Megan Mitzelfelt Pdf

Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases

Author : A Crain,L J GuilletteJr
Publisher : CRC Press
Page : 355 pages
File Size : 49,9 Mb
Release : 2000-08-17
Category : Medical
ISBN : 1560325712

Get Book

Environmental Endocrine Disruptors by A Crain,L J GuilletteJr Pdf

Addresses many aspects of endocrine disruption by environmental encountered toxic substances. Initial chapters provide essential background information whilst later chapters address specific aspects of endocrine disrupting contaminants (EDC)

Author : Anonim
Publisher : DIANE Publishing
Page : 120 pages
File Size : 53,6 Mb
Release : 1997
Category : Electronic government information
ISBN : 9781428903784

Get Book

Special report on environmental endocrine disruption an effects assessment and analysis : prepared for the Risk Assessment Forum, U.S. Environmental Protection Agency. by Anonim Pdf

Author : Tracey J. Woodruff,Sarah J. Janssen,Louis J. Guillette, Jr,Linda C. Giudice
Publisher : Cambridge University Press
Page : 262 pages
File Size : 41,8 Mb
Release : 2010-01-28
Category : Medical
ISBN : 0521519527

Get Book

Environmental Impacts on Reproductive Health and Fertility by Tracey J. Woodruff,Sarah J. Janssen,Louis J. Guillette, Jr,Linda C. Giudice Pdf

Many reproductive and developmental health problems are caused by exposure to chemicals that are widely dispersed in our environment. These problems include infertility, miscarriage, poor pregnancy outcomes, abnormal fetal development, early puberty, endometriosis, and diseases and cancers of reproductive organs. The compelling nature of the collective science has resulted in recognition of a new field of environmental reproductive health. Focusing on exposures to environmental contaminants, particularly during critical periods in development and their potential effects on all aspects of future reproductive life-course, this book provides the first comprehensive source of information bringing together the arguments that are spread out among various scientific disciplines in environmental health, clinical and public health fields. It provides a review of the science in key areas of the relationship between environmental contaminants and reproductive health outcomes, and recommendations on efforts toward prevention in clinical care and public policy.

Author : Polyxeni Nicolopoulou-Stamati,Luc Hens,Vyvyan C. Howard
Publisher : Springer Science & Business Media
Page : 385 pages
File Size : 49,5 Mb
Release : 2013-03-14
Category : Medical
ISBN : 9789401597692

Get Book

Endocrine Disrupters by Polyxeni Nicolopoulou-Stamati,Luc Hens,Vyvyan C. Howard Pdf

During recent decades, millions of tonnes of man-made chemicals have been produced and released into the environment, with very little safety testing. Many of these chemical substances have been found to interfere with the endocrine system and modulate its function. This book not only overviews the effects of endocrine/disrupting substances on human health, but also addresses the regulatory problems from the point of view of international organisations, including the WHO, the EU, and the European Chlorine Industry. This volume contains the proceedings of a workshop held at the International Hippocrates Foundation on Kos Island, Greece, in September 1999. The workshop was part of the activities of the ASPIS project, which aims at raising awareness of environmental health impacts among multidisciplinary groups. The contributions to this volume are the result of the interaction of participants at the workshop. As such, it addresses the issue of endocrine disrupters from many different points of view and allows the subject to be approached by a multidisciplinary readership, including: decision makers, medical doctors, environmental experts, post/and undergraduate students, lawyers, engineers, and journalists.