Enzyme Catalysed Reactions

Author : Richard B. Silverman
Publisher : Elsevier
Page : 800 pages
File Size : 51,8 Mb
Release : 2002-03-07
Category : Science
ISBN : 9780080513362

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Organic Chemistry of Enzyme-Catalyzed Reactions, Revised Edition by Richard B. Silverman Pdf

The Organic Chemistry of Enzyme-Catalyzed Reactions is not a book on enzymes, but rather a book on the general mechanisms involved in chemical reactions involving enzymes. An enzyme is a protein molecule in a plant or animal that causes specific reactions without itself being permanently altered or destroyed. This is a revised edition of a very successful book, which appeals to both academic and industrial markets. Illustrates the organic mechanism associated with each enzyme-catalyzed reaction Makes the connection between organic reaction mechanisms and enzyme mechanisms Compiles the latest information about molecular mechanisms of enzyme reactions Accompanied by clearly drawn structures, schemes, and figures Includes an extensive bibliography on enzyme mechanisms covering the last 30 years Explains how enzymes can accelerate the rates of chemical reactions with high specificity Provides approaches to the design of inhibitors of enzyme-catalyzed reactions Categorizes the cofactors that are appropriate for catalyzing different classes of reactions Shows how chemical enzyme models are used for mechanistic studies Describes catalytic antibody design and mechanism Includes problem sets and solutions for each chapter Written in an informal and didactic style

Author : Charles John Gray
Publisher : Van Nostrand Reinhold Company
Page : 384 pages
File Size : 49,5 Mb
Release : 1971
Category : Science
ISBN : MINN:31951000464531Y

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Enzyme-catalysed Reactions by Charles John Gray Pdf

Author : Gertz I. Likhtenshtein
Publisher : Springer Science & Business Media
Page : 239 pages
File Size : 48,8 Mb
Release : 2007-05-08
Category : Science
ISBN : 9780306481109

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New Trends in Enzyme Catalysis and Biomimetic Chemical Reactions by Gertz I. Likhtenshtein Pdf

"This book is a view of enzyme catalysis by a physico-chemist with long-term experience in the investigation of structure and action mechanism of biological catalysts. This book is not intended to provide an exhaustive survey of each topic but rather a discussion of their theoretical and experimental background, and recent developments. The literature of enzyme catalysis is so vast and many scientists have made important contribution in the area, that it is impossible in the space allowed for this book to give a representative set of references. The author has tried to use reviews, and general principles of articles. He apologizes to those he has not been able to include. . ... The monograph is intended for scientists working on enzyme catalysis and adjacent areas such as chemical modeling of biological processes, homogeneous catalysis, biomedical research and biotechnology. The book can be use as a subsidiary manual for instructors, graduate and undergraduate students of university biochemistry and chemistry departments."--Pages ix-x.

Author : Richard B. Silverman
Publisher : Academic Press
Page : 737 pages
File Size : 47,9 Mb
Release : 2002-02-28
Category : Science
ISBN : 9780126437317

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Organic Chemistry of Enzyme-Catalyzed Reactions, Revised Edition- by Richard B. Silverman Pdf

The Organic Chemistry of Enzyme-Catalyzed Reactions is not a book on enzymes, but rather a book on the general mechanisms involved in chemical reactions involving enzymes. An enzyme is a protein molecule in a plant or animal that causes specific reactions without itself being permanently altered or destroyed. This is a revised edition of a very successful book, which appeals to both academic and industrial markets. Illustrates the organic mechanism associated with each enzyme-catalyzed reaction Makes the connection between organic reaction mechanisms and enzyme mechanisms Compiles the latest information about molecular mechanisms of enzyme reactions Accompanied by clearly drawn structures, schemes, and figures Includes an extensive bibliography on enzyme mechanisms covering the last 30 years Explains how enzymes can accelerate the rates of chemical reactions with high specificity Provides approaches to the design of inhibitors of enzyme-catalyzed reactions Categorizes the cofactors that are appropriate for catalyzing different classes of reactions Shows how chemical enzyme models are used for mechanistic studies Describes catalytic antibody design and mechanism Includes problem sets and solutions for each chapter Written in an informal and didactic style

Author : Dennis Piszkiewicz
Publisher : Unknown
Page : 262 pages
File Size : 47,9 Mb
Release : 1977
Category : Electronic
ISBN : 8210379456XXX

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Kinetics of Chemical and Enzyme-Catalyzed Reactions by Dennis Piszkiewicz Pdf

Author : Daniel L. Purich
Publisher : Elsevier
Page : 920 pages
File Size : 46,8 Mb
Release : 2010-06-16
Category : Science
ISBN : 9780123809254

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Enzyme Kinetics: Catalysis and Control by Daniel L. Purich Pdf

Far more than a comprehensive treatise on initial-rate and fast-reaction kinetics, this one-of-a-kind desk reference places enzyme science in the fuller context of the organic, inorganic, and physical chemical processes occurring within enzyme active sites. Drawing on 2600 references, Enzyme Kinetics: Catalysis & Control develops all the kinetic tools needed to define enzyme catalysis, spanning the entire spectrum (from the basics of chemical kinetics and practical advice on rate measurement, to the very latest work on single-molecule kinetics and mechanoenzyme force generation), while also focusing on the persuasive power of kinetic isotope effects, the design of high-potency drugs, and the behavior of regulatory enzymes. Historical analysis of kinetic principles including advanced enzyme science Provides both theoretical and practical measurements tools Coverage of single molecular kinetics Examination of force generation mechanisms Discussion of organic and inorganic enzyme reactions

Author : Anonim
Publisher : Academic Press
Page : 459 pages
File Size : 42,9 Mb
Release : 1991-01-28
Category : Technology & Engineering
ISBN : 0080865968

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Mechanisms of Catalysis by Anonim Pdf

The remarkable expansion of information leading to a deeper understanding of enzymes on the molecular level necessitated the development of this volume which not only introduces new topics to The Enzymes series but presents new information on some covered in Volume I and II of this edition.

Author : N.S. Punekar
Publisher : Springer
Page : 562 pages
File Size : 52,8 Mb
Release : 2018-11-11
Category : Science
ISBN : 9789811307850

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ENZYMES: Catalysis, Kinetics and Mechanisms by N.S. Punekar Pdf

This enzymology textbook for graduate and advanced undergraduate students covers the syllabi of most universities where this subject is regularly taught. It focuses on the synchrony between the two broad mechanistic facets of enzymology: the chemical and the kinetic, and also highlights the synergy between enzyme structure and mechanism. Designed for self-study, it explains how to plan enzyme experiments and subsequently analyze the data collected. The book is divided into five major sections: 1] Introduction to enzymes, 2] Practical aspects, 3] Kinetic Mechanisms, 4] Chemical Mechanisms, and 5] Enzymology Frontiers. Individual concepts are treated as stand-alone chapters; readers can explore any single concept with minimal cross-referencing to the rest of the book. Further, complex approaches requiring specialized techniques and involved experimentation (beyond the reach of an average laboratory) are covered in theory with suitable references to guide readers. The book provides students, researchers and academics in the broad area of biology with a sound theoretical and practical knowledge of enzymes. It also caters to those who do not have a practicing enzymologist to teach them the subject.

Author : Ari Koskinen,A. Klibanov
Publisher : Springer Science & Business Media
Page : 338 pages
File Size : 43,9 Mb
Release : 1995-12-31
Category : Science
ISBN : 0751402591

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Enzymatic Reactions in Organic Media by Ari Koskinen,A. Klibanov Pdf

The outlook of organic synthesis has changed many times during its tractable history. The initial focus on the synthesis of substances typical of living matter, exemplified by the first examples of organic chemistry through the synthesis of urea from inorganic substances by Liebig, was accepted as the birth of organic chemistry, and thus also of organic synthesis. Although the early developments in organic synthesis closely followed the pursuit of molecules typical in nature, towards the end of the 19th century, societal pressures placed higher demands on chemical methods appropriate for the emerging age of industrialization. This led to vast amounts of information being generated through the discovery of synthetic reactions, spectroscopic techniques and reaction mechanisms. The basic organic functional group transformations were discovered and improved during the early part of this century. Reaction mechanisms were elucidated at a growing pace, and extremely powerful spectroscopic tools, such as infrared, nuclear magnetic resonance and mass spectrometry were introduced as everyday tools for a practising organic chemist. By the 1950s, many practitioners were ready to agree that almost every molecule could be syn thesized. Some difficult stereochemical problems were exceptions; for example Woodward concluded that erythromycin was a "hopelessly complex target". This frustration led to a hectic phase of development of new and increasingly more ingenious protecting group strategies and functional group transformations, and also saw the emergence of asymmetric synthesis.

Author : Christopher T. Walsh,Yi Tang
Publisher : Royal Society of Chemistry
Page : 787 pages
File Size : 52,8 Mb
Release : 2017-04-28
Category : Science
ISBN : 9781788010764

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Natural Product Biosynthesis by Christopher T. Walsh,Yi Tang Pdf

This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.

Author : Paul C. Engel
Publisher : Springer
Page : 97 pages
File Size : 47,5 Mb
Release : 2013-11-21
Category : Science
ISBN : 9781489932785

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Enzyme Kinetics by Paul C. Engel Pdf

The student of biological science in his final years as an undergraduate and his first years as a graduate is expected to gain some familiarity with current research at the fron tiers of his discipline. New research work is published in a perplexing diversity of publications and is inevitably concerned with the minutiae of the subject. The sheer number of research journals and papers also causes confusion and difficulties of assimilation. Review articles usually presuppose a background knowledge of the field and are inevitably rather restricted in scope. There is thus a need for short but authoritative introductions to those areas of modern biological research which are either not dealt with in standard introductory text books or are not dealt with in sufficient detail to enable the student to go on from them to read scholarly reviews with profit. This series of books is designed to satisfy this need. The authors have been asked to produce abrief outline of their subject assuming that their readers will have read and remembered much of a standard introductory textbook of biology.

Author : Gavin Williams,Mélanie Hall
Publisher : Royal Society of Chemistry
Page : 594 pages
File Size : 44,7 Mb
Release : 2018-05-31
Category : Science
ISBN : 9781788014533

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Modern Biocatalysis by Gavin Williams,Mélanie Hall Pdf

The synergy between synthetic biology and biocatalysis is emerging as an important trend for future sustainable processes. This book reviews all modern and novel techniques successfully implemented in biocatalysis, in an effort to provide better performing enzymatic systems and novel biosynthetic routes to (non-)natural products. This includes the use of molecular techniques in protein design and engineering, construction of artificial metabolic pathways, and application of computational methods for enzyme discovery and design. Stress is placed on current ‘hot’ topics in biocatalysis, where recent advances in research are defining new grounds in enzyme-catalyzed processes. With contributions from leading academics around the world, this book makes a ground-breaking contribution to this progressive field and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology.

Author : Richard B. Silverman
Publisher : Unknown
Page : 717 pages
File Size : 51,6 Mb
Release : 2012
Category : Enzymes
ISBN : 9381269793

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The Organic Chemistry of Enzyme-catalyzed Reactions by Richard B. Silverman Pdf

Author : Paul Flowers,Richard Langely,William R. Robinson,Klaus Hellmut Theopold
Publisher : Unknown
Page : 0 pages
File Size : 51,8 Mb
Release : 2019-02-14
Category : Chemistry
ISBN : 194717262X

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Chemistry 2e by Paul Flowers,Richard Langely,William R. Robinson,Klaus Hellmut Theopold Pdf

Chemistry 2e is designed to meet the scope and sequence requirements of the two-semester general chemistry course. The textbook provides an important opportunity for students to learn the core concepts of chemistry and understand how those concepts apply to their lives and the world around them. The book also includes a number of innovative features, including interactive exercises and real-world applications, designed to enhance student learning. The second edition has been revised to incorporate clearer, more current, and more dynamic explanations, while maintaining the same organization as the first edition. Substantial improvements have been made in the figures, illustrations, and example exercises that support the text narrative. Changes made in Chemistry 2e are described in the preface to help instructors transition to the second edition.

Author : Soundar Divakar
Publisher : Springer Science & Business Media
Page : 300 pages
File Size : 40,8 Mb
Release : 2012-12-18
Category : Science
ISBN : 9788132208730

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Enzymatic Transformation by Soundar Divakar Pdf

Transformations using enzymes have been extensively investigated in the last two decades and the results promise great potential for this growing field, especially in the area of synthetic organic chemistry mainly due to of its many advantages. Accordingly, this book has attempted to bring out the advantages of using enzymes involving complex underivatized and unprotected substrates in non-polar media under homogenous and heterogeneous reaction conditions. Merits and demerits of using enzymes in terms of yields and selectivity/specificity are presented without any prejudice. Almost all the reactions dealt with are from the author’s laboratory comprising diverse substrates, and the catalysis involves two important hydrolyzing enzymes, extensively examined for the reverse reactions. Thus, esterification involving lipses and glycosylation involving glycosidases were investigated with respect to various strategies like optimization of reaction conditions, response surface methodology and kinetics, carrying out reactions under solvent, non-solvent and super critical carbon dioxide conditions. In short, the work presented is to ensure the comprehension of the problems faced by the researchers in this area so as to work out further efficient strategies for carrying out enzymatic transformations in the laboratory successfully with better yields and specificity.