Epigenetics And Human Reproduction

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Epigenetics and Human Reproduction

Author : Sophie Rousseaux,Saadi Khochbin
Publisher : Springer Science & Business Media
Page : 372 pages
File Size : 43,7 Mb
Release : 2010-11-03
Category : Medical
ISBN : 9783642147739

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Epigenetics and Human Reproduction by Sophie Rousseaux,Saadi Khochbin Pdf

Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction

Epigenetics In Human Reproduction And Development

Author : Naumova Anna K,Taketo-hosotani Teruko
Publisher : World Scientific
Page : 304 pages
File Size : 55,8 Mb
Release : 2016-12-20
Category : Medical
ISBN : 9789813144286

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Epigenetics In Human Reproduction And Development by Naumova Anna K,Taketo-hosotani Teruko Pdf

Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood. Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data.

Epigenetics in Human Reproduction and Development

Author : Anna K. Naumova,Teruko Taketo
Publisher : Unknown
Page : 304 pages
File Size : 45,6 Mb
Release : 2016
Category : HEALTH & FITNESS
ISBN : 9813144270

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Epigenetics in Human Reproduction and Development by Anna K. Naumova,Teruko Taketo Pdf

"Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood. Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data."--Publisher's website.

Epigenetics and Human Reproduction

Author : Sophie Rousseaux,Saadi Khochbin
Publisher : Springer
Page : 372 pages
File Size : 47,5 Mb
Release : 2010-11-05
Category : Medical
ISBN : 3642147720

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Epigenetics and Human Reproduction by Sophie Rousseaux,Saadi Khochbin Pdf

Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction

Epigenetics and Reproductive Health

Author : Anonim
Publisher : Academic Press
Page : 464 pages
File Size : 47,6 Mb
Release : 2020-09-12
Category : Medical
ISBN : 9780128197547

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Epigenetics and Reproductive Health by Anonim Pdf

Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted reproductive technologies. Emphasis is placed on identifying biomarkers for early detection of aberrant epigenetic mechanisms. Later chapters examine the possibility of correcting these epigenetic dysfunctions, as well as current challenges and next steps in research, enabling new translational discoveries and efforts towards developing therapeutics. Thoroughly examines the influence of aberrant epigenetics during gametogenesis and embryogenesis, affecting parents, gametes and embryos, offspring and future generations Explores health outcomes for reproductive senescence, endocrine disruption, testicular cancer, prostrate cancer, breast cancer, ovarian, cancer, endometrial cancer and cervical cancers Features chapter contributions from international researchers in the field

Epigenetics and Epigenomics

Author : Christopher J. Payne
Publisher : BoD – Books on Demand
Page : 222 pages
File Size : 50,9 Mb
Release : 2014-04-29
Category : Medical
ISBN : 9789535113638

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Epigenetics and Epigenomics by Christopher J. Payne Pdf

The book aims to provide an overview of current knowledge regarding epigenetics and epigenomics. Included are reviews on the role of epigenetics in the development and pathogenesis of the vascular endothelium and nervous system, as well as our current understanding of the potential etiologies of Autism Spectrum Disorders. Additional chapters are devoted to DNA methylation, genomic imprinting and human reproduction. A discussion of the role of the epigenome in cancer prevention and polyphenols is also included. Authors provide research findings from both human data and animal model studies. This book will be of interest to scientists, physicians and lay readers wishing to review recent developments in the field of epigenetics and epigenomics.

Epigenetics and Assisted Reproduction

Author : Cristina Camprubí,Joan Blanco
Publisher : CRC Press
Page : 330 pages
File Size : 48,5 Mb
Release : 2018-09-03
Category : Medical
ISBN : 9781351804448

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Epigenetics and Assisted Reproduction by Cristina Camprubí,Joan Blanco Pdf

Epigenetics is the study of how certain genes are activated without modification at the DNA sequence level, resulting in genetically similar individuals having different clinical outcomes. As contemporary medicine increasingly aims to personalize the medical approach to a patient's genetic profile, the factors that can affect which genes are expressed also increase in importance and relevance to the clinician. This text from experts will give the clinician in Reproductive Medicine a reliable grounding in current thinking and research on this fast-moving topic, with many clinical implications.

Textbook of Human Reproductive Genetics

Author : Stéphane Viville,Karen D. Sermon
Publisher : Cambridge University Press
Page : 255 pages
File Size : 53,8 Mb
Release : 2022-12-31
Category : Medical
ISBN : 9781009197724

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Textbook of Human Reproductive Genetics by Stéphane Viville,Karen D. Sermon Pdf

This book combines genetics, reproductive biology and medicine for an integrative view of the emerging specialism of reproductive genetics.

Human Reproductive Genetics

Author : Juan A. Garcia-Velasco,Emre Seli
Publisher : Academic Press
Page : 342 pages
File Size : 45,5 Mb
Release : 2020-04-19
Category : Medical
ISBN : 9780128167496

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Human Reproductive Genetics by Juan A. Garcia-Velasco,Emre Seli Pdf

Human Reproductive Genetics: Emerging Technologies and Clinical Applications presents a great reference for clinicians and researchers in reproductive medicine. Part I includes a brief background of genetics and epigenetics, probability of disease, and the different techniques that are being used today for analysis and genetic counseling. Part II focuses on the analysis of the embryo, current controversies and future concepts. Part III comprises different clinical scenarios that clinicians frequently face in practice. The increasing amount of genetic tests available and the growing information that patients handle makes this section a relevant part of the fertility treatment discussion. Finally, Part IV concludes with the psychological aspects of genetic counseling and the role of counselor and bioethics in human reproduction. Provides an essential reference for clinicians involved in reproductive medicine Builds foundational knowledge on new genetic tests coming into the clinical scenario for physicians involved with patients Assembles critically evaluated chapters that cover basic concepts of genetics and epigenetics and the techniques involved, including preimplantation genetic testing, controversies, and more

Transgenerational Epigenetics

Author : Trygve Tollefsbol
Publisher : Elsevier
Page : 413 pages
File Size : 48,8 Mb
Release : 2014-05-02
Category : Science
ISBN : 9780124059221

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Transgenerational Epigenetics by Trygve Tollefsbol Pdf

Transgenerational Epigenetics provides a comprehensive analysis of the inheritance of epigenetic phenomena between generations. Recent research points to the existence of biological phenomena that are controlled not through gene mutations, but rather through reversible and heritable epigenetic processes. Epidemiological studies have suggested that environmental factors may be heritable. In fact, environmental factors often play a role in transgenerational epigenetics, which may have selective or adverse effects on the offspring. This epigenetic information can be transferred through a number of mechanisms including DNA methylation, histone modifications or RNA and the effects can persist for multiple generations. This book examines the evolution of epigenetic inheritance, its expression in animal and plant models, and how human diseases, such as metabolic disorders and cardiovascular diseases, appear to be affected by transgenerational epigenetic inheritance. It discusses clinical interventions in transgenerational epigenetic inheritance that may be on the horizon to help prevent diseases before the offspring are born, or to reduce the severity of diseases at the very earliest stages of development in utero, and current controversies in this area of study, as well as future directions for research. Focused discussion of metabolic disorders, cardiovascular diseases and longevity, which appear most affected by reversible and heritable epigenetic processes Encompasses both foundational and clinical aspects including discussions of preventative in utero therapies Covers history, future outlook, disease management and current controversies

Textbook of Human Reproductive Genetics

Author : Stéphane Viville,Karen D. Sermon
Publisher : Cambridge University Press
Page : 255 pages
File Size : 54,6 Mb
Release : 2022-12-31
Category : Medical
ISBN : 9781009197694

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Textbook of Human Reproductive Genetics by Stéphane Viville,Karen D. Sermon Pdf

A basic understanding of human genetics is vital for all those working in the field of assisted human reproduction. Genetic makeup can hamper reproduction and insight into this is making genetic diagnosis and counselling increasingly important. This fully updated textbook continues the clear structure of the original edition, beginning with a chapter on the basics of genetics and cytogenetics. Genetic causes of infertility and the effect of epigenetics and transposons on fertility are discussed in detail. Several new chapters are included in this edition, reflecting the advances of the field, including preconception genetic analysis and screening in IVF and mitochondrial genetics. Combining genetics, reproductive biology and medicine, this is an essential text for practitioners in reproductive medicine and geneticists involved in the field looking to improve their knowledge of the subject and provide outstanding patient care.

The Epigenetics Revolution

Author : Nessa Carey
Publisher : Columbia University Press
Page : 353 pages
File Size : 42,6 Mb
Release : 2012-03-06
Category : Science
ISBN : 9780231530712

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The Epigenetics Revolution by Nessa Carey Pdf

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.

Introduction to Epigenetics

Author : Renato Paro,Ueli Grossniklaus,Raffaella Santoro,Anton Wutz
Publisher : Springer Nature
Page : 215 pages
File Size : 48,9 Mb
Release : 2021-03-23
Category : Science
ISBN : 9783030686703

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Introduction to Epigenetics by Renato Paro,Ueli Grossniklaus,Raffaella Santoro,Anton Wutz Pdf

This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease

Environmental Epigenetics

Author : L. Joseph Su,Tung-chin Chiang
Publisher : Springer
Page : 321 pages
File Size : 41,9 Mb
Release : 2015-05-18
Category : Medical
ISBN : 9781447166788

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Environmental Epigenetics by L. Joseph Su,Tung-chin Chiang Pdf

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

The Genetics of Male Infertility

Author : Douglas T. Carrell
Publisher : Springer Science & Business Media
Page : 337 pages
File Size : 52,9 Mb
Release : 2007-11-08
Category : Medical
ISBN : 9781597451765

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The Genetics of Male Infertility by Douglas T. Carrell Pdf

In this book, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments. New tools discussed are discussed. This book therefore serves as a guide to evidence-based clinical applications, and a preview of future possibilities.