Epigenetics And Reproductive Health

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Epigenetics and Reproductive Health

Author : Anonim
Publisher : Academic Press
Page : 464 pages
File Size : 44,9 Mb
Release : 2020-09-12
Category : Medical
ISBN : 9780128197547

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Epigenetics and Reproductive Health by Anonim Pdf

Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted reproductive technologies. Emphasis is placed on identifying biomarkers for early detection of aberrant epigenetic mechanisms. Later chapters examine the possibility of correcting these epigenetic dysfunctions, as well as current challenges and next steps in research, enabling new translational discoveries and efforts towards developing therapeutics. Thoroughly examines the influence of aberrant epigenetics during gametogenesis and embryogenesis, affecting parents, gametes and embryos, offspring and future generations Explores health outcomes for reproductive senescence, endocrine disruption, testicular cancer, prostrate cancer, breast cancer, ovarian, cancer, endometrial cancer and cervical cancers Features chapter contributions from international researchers in the field

Epigenetics and Human Reproduction

Author : Sophie Rousseaux,Saadi Khochbin
Publisher : Springer Science & Business Media
Page : 372 pages
File Size : 53,6 Mb
Release : 2010-11-03
Category : Medical
ISBN : 9783642147739

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Epigenetics and Human Reproduction by Sophie Rousseaux,Saadi Khochbin Pdf

Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction

Epigenetics and Assisted Reproduction

Author : Cristina Camprubí,Joan Blanco
Publisher : CRC Press
Page : 330 pages
File Size : 41,8 Mb
Release : 2018-09-03
Category : Medical
ISBN : 9781351804448

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Epigenetics and Assisted Reproduction by Cristina Camprubí,Joan Blanco Pdf

Epigenetics is the study of how certain genes are activated without modification at the DNA sequence level, resulting in genetically similar individuals having different clinical outcomes. As contemporary medicine increasingly aims to personalize the medical approach to a patient's genetic profile, the factors that can affect which genes are expressed also increase in importance and relevance to the clinician. This text from experts will give the clinician in Reproductive Medicine a reliable grounding in current thinking and research on this fast-moving topic, with many clinical implications.

Epigenetics and Human Reproduction

Author : Sophie Rousseaux,Saadi Khochbin
Publisher : Springer
Page : 372 pages
File Size : 44,8 Mb
Release : 2010-11-05
Category : Medical
ISBN : 3642147720

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Epigenetics and Human Reproduction by Sophie Rousseaux,Saadi Khochbin Pdf

Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction

Epigenetics In Human Reproduction And Development

Author : Naumova Anna K,Taketo-hosotani Teruko
Publisher : World Scientific
Page : 304 pages
File Size : 44,7 Mb
Release : 2016-12-20
Category : Medical
ISBN : 9789813144286

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Epigenetics In Human Reproduction And Development by Naumova Anna K,Taketo-hosotani Teruko Pdf

Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood. Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data.

Infertile Environments

Author : Janelle Lamoreaux
Publisher : Duke University Press
Page : 88 pages
File Size : 44,8 Mb
Release : 2022-11-18
Category : Social Science
ISBN : 9781478023975

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Infertile Environments by Janelle Lamoreaux Pdf

In Infertile Environments, Janelle Lamoreaux investigates how epigenetic research into the effects of toxic exposure conceptualizes and configures environments. Drawing on fieldwork in a Nanjing, China, toxicology lab that studies the influence of pesticides and other pollutants on male reproductive and developmental health, Lamoreaux shows how the lab’s everyday research practices bring national, hormonal, dietary, maternal, and laboratory environments into being. She situates the lab’s work within broader Chinese history as well as the contemporary cultural and political moment, in which declining fertility rates and reproductive governance and technology are growing concerns. She also points to how toxicology in China is a transnational endeavor tied to both local conditions and international research agendas and infrastructures, which highlights the myriad scales and scope of epigenetic environments. At a moment of growing concerns about toxins, endocrine-disrupting chemicals, and climate change, Lamoreaux demonstrates that epigenetic research’s proliferation of environments produces new kinds of toxic relations that impact multiple generations of humans.

Weighing the Future

Author : Natali Valdez
Publisher : Univ of California Press
Page : 289 pages
File Size : 44,7 Mb
Release : 2021-12-14
Category : Health & Fitness
ISBN : 9780520380134

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Weighing the Future by Natali Valdez Pdf

"Epigenetics is the study of heritable changes in gene expression and has been heralded as one of the most promising new fields of scientific inquiry. Current large-scale pregnancy studies draw on epigenetics to connect pregnant women's behavioral choices, like diet and exercise, to future health risks for unborn babies. As the first ethnography of its kind, Weighing the Future examines the sociopolitical implications of ongoing pregnancy trials in the United States and the United Kingdom, illuminating how processes of scientific knowledge production are linked to capitalism, surveillance, and environmental reproduction. The environments we imagine to shape our genes, bodies, and future health are tied to race, gender, and structures of inequality. This groundbreaking book makes the case that science, and how we translate it, is a reproductive project that requires feminist vigilance. Instead of fixating on a future at risk, this book brings attention to the present at stake"--

Textbook of Human Reproductive Genetics

Author : Stéphane Viville,Karen D. Sermon
Publisher : Cambridge University Press
Page : 255 pages
File Size : 45,9 Mb
Release : 2022-12-31
Category : Medical
ISBN : 9781009197724

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Textbook of Human Reproductive Genetics by Stéphane Viville,Karen D. Sermon Pdf

This book combines genetics, reproductive biology and medicine for an integrative view of the emerging specialism of reproductive genetics.

Environmental Epigenetics

Author : L. Joseph Su,Tung-chin Chiang
Publisher : Springer
Page : 321 pages
File Size : 55,7 Mb
Release : 2015-05-18
Category : Medical
ISBN : 9781447166788

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Environmental Epigenetics by L. Joseph Su,Tung-chin Chiang Pdf

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Developmental Origins of Health and Disease

Author : Peter Gluckman,Mark Hanson
Publisher : Cambridge University Press
Page : 542 pages
File Size : 50,5 Mb
Release : 2006-04-20
Category : Medical
ISBN : 0521847435

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Developmental Origins of Health and Disease by Peter Gluckman,Mark Hanson Pdf

This landmark publication provides the first definitive account of how and why subtle influences on the fetus and during early life can have such profound consequences for adult health and diseases. Although the epidemiological evidence for this link has long proved compelling, it is only much more recently that the scientific and physiological basis has begun to be studied in depth and fully understood. The compilation, written by many of the world's leading experts in this exciting field, summarizes these scientific and clinical advances.

Epigenetics in Human Disease

Author : Trygve O. Tollefsbol
Publisher : Academic Press
Page : 618 pages
File Size : 40,8 Mb
Release : 2012-07-26
Category : Medical
ISBN : 9780123884152

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Epigenetics in Human Disease by Trygve O. Tollefsbol Pdf

Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs

Epigenetics in Human Reproduction and Development

Author : Anna K. Naumova,Teruko Taketo
Publisher : Unknown
Page : 304 pages
File Size : 54,5 Mb
Release : 2016
Category : HEALTH & FITNESS
ISBN : 9813144270

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Epigenetics in Human Reproduction and Development by Anna K. Naumova,Teruko Taketo Pdf

"Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood. Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data."--Publisher's website.

Epigenetic Epidemiology

Author : Karin B. Michels
Publisher : Springer Science & Business Media
Page : 450 pages
File Size : 48,5 Mb
Release : 2012-01-02
Category : Medical
ISBN : 9789400724952

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Epigenetic Epidemiology by Karin B. Michels Pdf

The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored.This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laboratory techniques, the influence of age and environmental factors on shaping the epigenome, the role of epigenetics in the developmental origins hypothesis, and provides the state of the art on the epigenetic epidemiology of various health conditions including childhood syndromes, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, autism and other neurodevelopmental disorders, psychiatric disorders, diabetes, obesity and metabolic disorders, and atherosclerosis. With contributions from: Peter Jones, Jean-Pierre Issa, Gavin Kelsey, Robert Waterland, and many other experts in epigenetics!

Towards Reproductive Certainty: Fertility and Genetics Beyond 1999: The Plenary Proceedings of the 11th World Congress

Author : R. Jansen,D. Mortimer
Publisher : CRC Press
Page : 556 pages
File Size : 43,8 Mb
Release : 1999-04-15
Category : Medical
ISBN : 1850700842

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Towards Reproductive Certainty: Fertility and Genetics Beyond 1999: The Plenary Proceedings of the 11th World Congress by R. Jansen,D. Mortimer Pdf

This is a forward-looking clinical reference of definitive authority on today's headline controversies surrounding in vitro fertilization (IVF) and reproductive genetics. Written by leading experts from medicine, education, psychology, ethics, counseling, and other disciplines studying fertility and genetics, the book contains nearly 70 chapters in seven sections. The introductory section deals with biology, business, morality and society in IVF and reproductive genetics; other sections focus on IVF outcomes, personal ethics and business, biology of the egg, sperm and embryo, implantation, IVF and society, and such 21st century topics as space travel and human reproduction, the disappearing male,and the future of motherhood. Includes bibliographic references and index.

Human Reproductive Genetics

Author : Juan A. Garcia-Velasco,Emre Seli
Publisher : Academic Press
Page : 342 pages
File Size : 42,8 Mb
Release : 2020-04-19
Category : Medical
ISBN : 9780128167496

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Human Reproductive Genetics by Juan A. Garcia-Velasco,Emre Seli Pdf

Human Reproductive Genetics: Emerging Technologies and Clinical Applications presents a great reference for clinicians and researchers in reproductive medicine. Part I includes a brief background of genetics and epigenetics, probability of disease, and the different techniques that are being used today for analysis and genetic counseling. Part II focuses on the analysis of the embryo, current controversies and future concepts. Part III comprises different clinical scenarios that clinicians frequently face in practice. The increasing amount of genetic tests available and the growing information that patients handle makes this section a relevant part of the fertility treatment discussion. Finally, Part IV concludes with the psychological aspects of genetic counseling and the role of counselor and bioethics in human reproduction. Provides an essential reference for clinicians involved in reproductive medicine Builds foundational knowledge on new genetic tests coming into the clinical scenario for physicians involved with patients Assembles critically evaluated chapters that cover basic concepts of genetics and epigenetics and the techniques involved, including preimplantation genetic testing, controversies, and more