Ethics And Governance Of Biomedical Research

Author : Daniel Strech,Marcel Mertz
Publisher : Springer
Page : 225 pages
File Size : 42,8 Mb
Release : 2016-05-09
Category : Philosophy
ISBN : 9783319287317

Get Book

Ethics and Governance of Biomedical Research by Daniel Strech,Marcel Mertz Pdf

In this book, scholars with different disciplinary and national backgrounds argue for possible answers and analyse case studies on current issues of governance in biomedical research. These issues comprise among others the research-care distinction, risk evaluation in early human trials, handling of incidental findings, nocebo effects, cluster randomized trials, publication bias, or consent in biobank research. This book demonstrates how new technologies and research possibilities multiply or intensify already known governance challenges, leaving room for ethical analysis and complex moral choices. Clinical researchers, research ethics committee members and research ethicists have all to deal with such challenges on a daily basis. While general reflection on core concepts of research ethics is seldom pointless, those confronted with hard moral choices do need more practical and contextualized reflection on the said issues. This book particularly provides such contextualized reflections and aims to inform all those who study, conduct, regulate, fund, or participate in biomedical research.

Author : Brent Daniel Mittelstadt,Luciano Floridi
Publisher : Springer
Page : 480 pages
File Size : 48,9 Mb
Release : 2016-08-03
Category : Philosophy
ISBN : 9783319335254

Get Book

The Ethics of Biomedical Big Data by Brent Daniel Mittelstadt,Luciano Floridi Pdf

This book presents cutting edge research on the new ethical challenges posed by biomedical Big Data technologies and practices. ‘Biomedical Big Data’ refers to the analysis of aggregated, very large datasets to improve medical knowledge and clinical care. The book describes the ethical problems posed by aggregation of biomedical datasets and re-use/re-purposing of data, in areas such as privacy, consent, professionalism, power relationships, and ethical governance of Big Data platforms. Approaches and methods are discussed that can be used to address these problems to achieve the appropriate balance between the social goods of biomedical Big Data research and the safety and privacy of individuals. Seventeen original contributions analyse the ethical, social and related policy implications of the analysis and curation of biomedical Big Data, written by leading experts in the areas of biomedical research, medical and technology ethics, privacy, governance and data protection. The book advances our understanding of the ethical conundrums posed by biomedical Big Data, and shows how practitioners and policy-makers can address these issues going forward.

Author : Deborah Mascalzoni
Publisher : Springer
Page : 275 pages
File Size : 47,7 Mb
Release : 2015-01-22
Category : Medical
ISBN : 9789401795739

Get Book

Ethics, Law and Governance of Biobanking by Deborah Mascalzoni Pdf

Biobank research and genomic information are changing the way we look at health and medicine. Genomics challenges our values and has always been controversial and difficult to regulate. In the future lies the promise of tailored medical treatments and pharmacogenomics but the borders between medical research and clinical practice are becoming blurred. We see sequencing platforms for research that can have diagnostic value for patients. Clinical applications and research have been kept separate, but the blurring lines challenges existing regulations and ethical frameworks. Then how do we regulate it? This book contains an overview of the existing regulatory landscape for biobank research in the Western world and some critical chapters to show how regulations and ethical frameworks are developed and work. How should international sharing work? How design an ethical informed consent? An underlying critique: the regulatory systems are becoming increasingly complex and opaque. The international community is building systems that should respond to that. According to the authors in fact, it is time to turn the ship around. Biobank researchers have a moral responsibility to look at and assess their work in relation to the bigger picture: the shared norms and values of current society. Research ethics shouldn’t only be a matter of bioethicists writing guidelines that professionals have to follow. Ethics should be practiced through discourse and regulatory frameworks need to be part of that public discourse. Ethics review should be then not merely application of bureaucracy and a burden for researchers but an arena where researchers discuss their projects, receive advice and practice their ethics skills.

Author : Kiarash Aramesh
Publisher : Springer Nature
Page : 180 pages
File Size : 48,6 Mb
Release : 2019-11-13
Category : Philosophy
ISBN : 9783030311322

Get Book

An Ethical Framework for Global Governance for Health Research by Kiarash Aramesh Pdf

This book provides a comprehensive description and ethical analysis of one of the most challenging areas: international health research. Furthermore, it provides a vivid portrait of the current situation of global governance for health research and its main challenges and suggests a comprehensive and universal ethical framework based on the existing theories and frameworks. This work is a must-read for all the students, scholars, professionals, activists, and policy-makers who are involved or interested in the global health research enterprise and its governance and ethics.

Author : John Elliott,W. Calvin Ho,Sylvia S. N. Lim
Publisher : World Scientific
Page : 343 pages
File Size : 46,9 Mb
Release : 2010
Category : Medical
ISBN : 9789814327114

Get Book

Bioethics in Singapore by John Elliott,W. Calvin Ho,Sylvia S. N. Lim Pdf

This book provides an analysis of the ways in which the BAC has established an ethical framework for biomedical research in Singapore, following the launch of the Biomedical Sciences Initiative by the Singapore Government. The editors and authors have an intimate knowledge of the working of the BAC, and the focus of the book includes the ways in which international forces have influenced the form and substance of bioethics in Singapore. Together, the authors offer a comparative account of the institutionalisation of biomedical research ethics in Singapore, considered in the wider context of international regulatory efforts. The book reviews the work of the BAC by placing it within the broader cultural, social and political discourses that have emerged in relation to the life sciences since the turn of the 21st century. This book is not primarily intended to be a retrospect or an appraisal of the contribution of the BAC, though this is one aspect of it. Rather, the main intention is to make a substantive contribution to the rapidly emerging field of bioethics. Ethical discussions in the book include consideration of stem cell research and cloning, genetics and research with human participants, and focus on likely future developments as well as the past.Many of the contributors of the book have been personally involved in this work, and hence they write with an authoritative first-hand knowledge that scholars in bioethics and public policy may appreciate. As indicated above, the book also explains the way in which ethics and science ? international and local ? have interacted in a policy setting. Scholars and policy makers may find the Singaporean experience to be a valuable resource, as the approach has been to make the ethical governance of research in Singapore consistent with international best practice while observing the requirements of a properly localised application of universally accepted principles. In addition, at least three chapters (the first three chapters in particular) are accessible to the lay reader interested in the development of bioethics and biomedical sciences, both inside and outside Singapore, from 2000 (the year in which the BAC was established). Both scholars and interested lay readers are therefore likely to find this publication a valuable reference.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 50,5 Mb
Release : 2024-06-29
Category : Electronic
ISBN : 9789814462723

Get Book

Bioethics in Singapore by Anonim Pdf

Author : United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research
Publisher : Unknown
Page : 614 pages
File Size : 49,8 Mb
Release : 1978
Category : Human experimentation in medicine
ISBN : UCSD:31822000897728

Get Book

The Belmont Report by United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research Pdf

Author : Salla Sariola,Bob Simpson
Publisher : Cornell University Press
Page : 222 pages
File Size : 48,6 Mb
Release : 2019-03-15
Category : Technology & Engineering
ISBN : 9781501733611

Get Book

Research as Development by Salla Sariola,Bob Simpson Pdf

In Research as Development, Salla Sariola and Bob Simpson show how international collaboration operates in a setting that is typically portrayed as "resource-poor" and "scientifically lagging." Based on their long-term fieldwork in Sri Lanka, Sariola and Simpson bring into clear ethnographic focus the ways international scientific collaborations feature prominently in the pursuit of global health in which research operates "as" development and not merely "for" it. The authors follow the design, inception, and practice of two clinical trials: one a global health charity funded trial and the other a pharmaceutical industry-sponsored trial. Research as Development situates these two trials within their historical, political and cultural contexts and thus counters the idea that local actors are merely passive recipients of new technical and scientific rationalities. While social studies of clinical trials are beginning to be an established niche in academic writing, Research as Development helps fill important gaps in the literature through its examination of clinical research situated in cultures in low-income settings. Research as Development is noteworthy for the way it highlights the critical and creative role that local researchers play in establishing international collaborations and making them work into locally viable forms. The volume shows how these clinical and research interactions bring about changes in culture, technologies and expertise in Sri Lanka, contexts that have not previously been written about in any detail.

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy
Publisher : National Academies Press
Page : 133 pages
File Size : 48,9 Mb
Release : 2020-09-10
Category : Medical
ISBN : 9780309676632

Get Book

An Examination of Emerging Bioethical Issues in Biomedical Research by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy Pdf

On February 26, 2020, the Board on Health Sciences Policy of the National Academies of Sciences, Engineering, and Medicine hosted a 1-day public workshop in Washington, DC, to examine current and emerging bioethical issues that might arise in the context of biomedical research and to consider research topics in bioethics that could benefit from further attention. The scope of bioethical issues in research is broad, but this workshop focused on issues related to the development and use of digital technologies, artificial intelligence, and machine learning in research and clinical practice; issues emerging as nontraditional approaches to health research become more widespread; the role of bioethics in addressing racial and structural inequalities in health; and enhancing the capacity and diversity of the bioethics workforce. This publication summarizes the presentations and discussions from the workshop.

Author : Cheluchi Onyemelukwe-Onuobia
Publisher : Routledge
Page : 268 pages
File Size : 47,7 Mb
Release : 2018-09-06
Category : Business & Economics
ISBN : 9781351713054

Get Book

Health Research Governance in Africa by Cheluchi Onyemelukwe-Onuobia Pdf

The globalisation of research has resulted in the increased location of research involving humans in developing countries. Countries in Africa, along with China and India, have seen research grow significantly. With emerging infectious diseases, such as Ebola and Zika, emphasising the risk of public health crises throughout the world, a further increase in health research, including clinical research in developing countries, which are often the sites of these diseases, becomes inevitable. This growth raises questions about domestic regulation and the governance of health research. This book presents a comprehensive and systemic view of the regulation of research involving humans in African countries. It employs case studies from four countries in which research activities continue to rise, and which have taken steps to regulate health research activity: South Africa, Nigeria, Kenya, and Egypt. The book examines the historical and political contexts of these governance efforts. It describes the research context, some of the research taking place, and the current challenges. It also looks at the governance mechanisms, ranging from domestic ethical guidelines to legal frameworks, the strengthening of existing regulatory agencies to the role of professional regulatory bodies. The book analyses the adequacy of current governance arrangements within African countries, and puts forward recommendations to improve the emerging governance systems for health research in African and other developing countries. It book will be a valuable resource for academics, researchers, practitioners and policy-makers working in the areas of health research, biomedical ethics, health law and regulation in developing countries.

Author : G. Van Steendam
Publisher : Unknown
Page : 144 pages
File Size : 41,5 Mb
Release : 1993
Category : Bioethics
ISBN : MSU:31293025050182

Get Book

Dealing with Ethical Problems Linked to Modern Biomedical Research by G. Van Steendam Pdf

Author : Duff William Ramus Waring,Trudo Lemmens
Publisher : University of Toronto Press
Page : 281 pages
File Size : 52,8 Mb
Release : 2006-01-01
Category : Medical
ISBN : 9780802086433

Get Book

Law and Ethics in Biomedical Research by Duff William Ramus Waring,Trudo Lemmens Pdf

When a young man named Jesse Gelsinger died in 1999 as a result of his participation in a gene transfer research study, regulatory agencies in the United States began to take a closer look at what was happening in medical research. The resulting temporary shutdown of some of the most prestigious academic research centres confirmed what various recent reports in the United States as well as Canada had claimed; that the current system of regulatory oversight was in need of improvement. Law and Ethics in Biomedical Research uses the Gelinger case as a touchstone, illustrating how three major aspects of that case - the flaws in the regulatory system, conflicts of interest, and legal liability - embody the major challenges in the current medical research environment. Editors Trudo Lemmens and Duff R. Waring, along with a host of top scholars in the field, demonstrate why existing models of research review and human subject protection are in need of improvement, and how more stringent regulatory and legal means can be used to strengthen the protection of research subjects and the integrity of research. The contributors also address conflicts of interest, paying particular attention to the growing commercialization of medical research, as well as the legal liability of scientific investigators, research institutions, and governmental agencies. Legal liability is a growing concern in medical research and this fascinating study is, in the international context, one of the first to explore the liability of various parties involved in the research enterprise.

Author : Stephen Holland
Publisher : Rowman & Littlefield
Page : 170 pages
File Size : 45,7 Mb
Release : 2019-10-04
Category : Philosophy
ISBN : 9781786600578

Get Book

Ethics and Governance of Public Health Information by Stephen Holland Pdf

This book analyses current ethical issues in public health research.

Author : Baruch A. Brody
Publisher : Oxford University Press, USA
Page : 412 pages
File Size : 49,5 Mb
Release : 1998
Category : Medical
ISBN : 0195090071

Get Book

The Ethics of Biomedical Research by Baruch A. Brody Pdf

Examines the many ethical issues related to biomedical research, including the use of animals in research, research on human subjects, clinical trials, international research ethics policies, and other related topics.

Author : United States. Congress. House. Committee on Interstate and Foreign Commerce. Subcommittee on Public Health and Environment
Publisher : Unknown
Page : 312 pages
File Size : 50,8 Mb
Release : 1974
Category : Government publications
ISBN : LOC:00184237878

Get Book

Biomedical Research Ethics and the Protection of Human Research Subjects by United States. Congress. House. Committee on Interstate and Foreign Commerce. Subcommittee on Public Health and Environment Pdf