Fluorescence Lineshape Studies Of Thermal Unfolding And Secondary Structure Transitions In Proteins

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Biophysical Characterization of Proteins in Developing Biopharmaceuticals

Author : Damian J. Houde,Steven A. Berkowitz
Publisher : Elsevier
Page : 586 pages
File Size : 45,9 Mb
Release : 2019-11-13
Category : Medical
ISBN : 9780444641748

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Biophysical Characterization of Proteins in Developing Biopharmaceuticals by Damian J. Houde,Steven A. Berkowitz Pdf

Biophysical Characterization of Proteins in Developing Biopharmaceuticals, Second Edition, presents the latest on the analysis and characterization of the higher-order structure (HOS) or conformation of protein based drugs. Starting from the very basics of protein structure, this book explains the best way to achieve this goal using key methods commonly employed in the biopharmaceutical industry. This book will help today’s industrial scientists plan a career in this industry and successfully implement these biophysical methodologies. This updated edition has been fully revised, with new chapters focusing on the use of chromatography and electrophoresis and the biophysical characterization of very large biopharmaceuticals. In addition, best practices of applying statistical analysis to biophysical characterization data is included, along with practical issues associated with the concept of a biopharmaceutical’s developability and the technical decision-making process needed when dealing with biophysical characterization data. Presents basic protein characterization methods and tools applicable to (bio)pharmaceutical research and development Highlights the capabilities and limitations of each technique Discusses the underlining science of each tool Empowers industrial biophysical chemists by providing a roadmap for applying biophysical tools Outlines the needs for new characterization and analytical tools in the biopharmaceutical industry

Methods in Protein Structure and Stability Analysis

Author : Vladimir N. Uversky,Evgeniĭ Anatolʹevich Permi︠a︡kov
Publisher : Nova Publishers
Page : 382 pages
File Size : 51,8 Mb
Release : 2007
Category : Circular dichroism
ISBN : 1600214045

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Methods in Protein Structure and Stability Analysis by Vladimir N. Uversky,Evgeniĭ Anatolʹevich Permi︠a︡kov Pdf

Protein Folding Kinetics

Author : Bengt Nölting
Publisher : Springer Science & Business Media
Page : 222 pages
File Size : 45,5 Mb
Release : 2005-12-05
Category : Science
ISBN : 9783540272786

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Protein Folding Kinetics by Bengt Nölting Pdf

First methods book which includes many detailed descriptions Absolutely needed and thus timely for the scientific community Comprises 15% more content and includes the mentioned special features

Faculties, Publications, and Doctoral Theses in Chemistry and Chemical Engineering at United States Universities

Author : American Chemical Society. Committee on Professional Training
Publisher : Unknown
Page : 1646 pages
File Size : 41,8 Mb
Release : 1991
Category : Chemical engineering
ISBN : PSU:000019257419

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Faculties, Publications, and Doctoral Theses in Chemistry and Chemical Engineering at United States Universities by American Chemical Society. Committee on Professional Training Pdf

Spin Glasses and Random Fields

Author : A. Peter Young
Publisher : World Scientific
Page : 454 pages
File Size : 43,5 Mb
Release : 1998
Category : Science
ISBN : 9789810232405

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Spin Glasses and Random Fields by A. Peter Young Pdf

The last few years have seen many developments in the study of ?frustrated? systems, such as spin glasses and random fields. In addition, the application of the idea of spin glasses to other branches of physics, such as vortex lines in high temperature superconductors, protein folding, structural glasses, and the vulcanization of rubber, has been flourishing. The earlier reviews are several years old, so now is an appropriate time to summarize the recent developments. The articles in this book have been written by leading researchers and include theoretical and experimental studies, and large-scale numerical work (using state-of-the-art algorithms designed specifically for spin-glass-type problems), as well as analytical studies.

Experimental Approaches of NMR Spectroscopy

Author : The Nuclear Magnetic Resonance Society of Japan
Publisher : Springer
Page : 636 pages
File Size : 40,8 Mb
Release : 2017-11-23
Category : Science
ISBN : 9789811059667

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Experimental Approaches of NMR Spectroscopy by The Nuclear Magnetic Resonance Society of Japan Pdf

This book describes the advanced developments in methodology and applications of NMR spectroscopy to life science and materials science. Experts who are leaders in the development of new methods and applications of life and material sciences have contributed an exciting range of topics that cover recent advances in structural determination of biological and material molecules, dynamic aspects of biological and material molecules, and development of novel NMR techniques, including resolution and sensitivity enhancement. First, this book particularly emphasizes the experimental details for new researchers to use NMR spectroscopy and pick up the potentials of NMR spectroscopy. Second, the book is designed for those who are involved in either developing the technique or expanding the NMR application fields by applying them to specific samples. Third, the Nuclear Magnetic Resonance Society of Japan has organized this book not only for NMR members of Japan but also for readers worldwide who are interested in using NMR spectroscopy extensively.

Protein Folding, Misfolding and Aggregation

Author : Victor Muñoz
Publisher : Royal Society of Chemistry
Page : 290 pages
File Size : 50,9 Mb
Release : 2008
Category : Science
ISBN : 9780854042579

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Protein Folding, Misfolding and Aggregation by Victor Muñoz Pdf

Protein folding and aggregation is the process by which newly synthesized proteins fold into the specific three-dimensional structures defining their biologically active states. It has always been a major focus of research in biochemistry and has often been seen as the unsolved second part of the genetic code. In the last 10 years we have witnessed a quantum leap in the research in this exciting area. Computational methods have improved to the extent of making possible to simulate the complete folding process of small proteins and the early stages of protein aggregation. Experimental methods h.

Advances in High Pressure Bioscience and Biotechnology II

Author : Roland Winter
Publisher : Springer Science & Business Media
Page : 490 pages
File Size : 40,9 Mb
Release : 2013-11-11
Category : Science
ISBN : 9783662056134

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Advances in High Pressure Bioscience and Biotechnology II by Roland Winter Pdf

With original work on marine and terrestrial microbiology, biochemistry, molecular biology, deep-sea diving, food science, and other industrial applications, this book covers the whole range of current high pressure bioscience. It will be welcomed by all industrial and academic researchers working in this field.

Physics Briefs

Author : Anonim
Publisher : Unknown
Page : 1224 pages
File Size : 55,6 Mb
Release : 1994
Category : Physics
ISBN : UOM:39015027857286

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Physics Briefs by Anonim Pdf

Protein Physics

Author : Alexei V. Finkelstein,Oleg Ptitsyn
Publisher : Elsevier
Page : 528 pages
File Size : 46,6 Mb
Release : 2016-06-22
Category : Science
ISBN : 9780081012369

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Protein Physics by Alexei V. Finkelstein,Oleg Ptitsyn Pdf

Protein Physics: A Course of Lectures covers the most general problems of protein structure, folding and function. It describes key experimental facts and introduces concepts and theories, dealing with fibrous, membrane, and water-soluble globular proteins, in both their native and denatured states. The book systematically summarizes and presents the results of several decades of worldwide fundamental research on protein physics, structure, and folding, describing many physical models that help readers make estimates and predictions of physical processes that occur in proteins. New to this revised edition is the inclusion of novel information on amyloid aggregation, natively disordered proteins, protein folding in vivo, protein motors, misfolding, chameleon proteins, advances in protein engineering & design, and advances in the modeling of protein folding. Further, the book provides problems with solutions, many new and updated references, and physical and mathematical appendices. In addition, new figures (including stereo drawings, with a special appendix showing how to use them) are added, making this an ideal resource for graduate and advanced undergraduate students and researchers in academia in the fields of biophysics, physics, biochemistry, biologists, biotechnology, and chemistry. Fully revised and expanded new edition based on the latest research developments in protein physics Written by the world's top expert in the field Deals with fibrous, membrane, and water-soluble globular proteins, in both their native and denatured states Summarizes, in a systematic form, the results of several decades of worldwide fundamental research on protein physics and their structure and folding Examines experimental data on protein structure in the post-genome era

Dynamics of Soft Matter

Author : VICTORIA GARCIA SAKAI,Christiane Alba-Simionesco,Sow Hsin Chen
Publisher : Springer Science & Business Media
Page : 455 pages
File Size : 41,7 Mb
Release : 2011-12-19
Category : Technology & Engineering
ISBN : 9781461407263

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Dynamics of Soft Matter by VICTORIA GARCIA SAKAI,Christiane Alba-Simionesco,Sow Hsin Chen Pdf

Dynamics of Soft Matter: Neutron Applications provides an overview of neutron scattering techniques that measure temporal and spatial correlations simultaneously, at the microscopic and/or mesoscopic scale. These techniques offer answers to new questions arising at the interface of physics, chemistry, and biology. Knowledge of the dynamics at these levels is crucial to understanding the soft matter field, which includes colloids, polymers, membranes, biological macromolecules, foams, emulsions towards biological & biomimetic systems, and phenomena involving wetting, friction, adhesion, or microfluidics. Emphasizing the complementarities of scattering techniques with other spectroscopic ones, this volume also highlights the potential gain in combining techniques such as rheology, NMR, light scattering, dielectric spectroscopy, as well as synchrotron radiation experiments. Key areas covered include polymer science, biological materials, complex fluids and surface science.

Bibliography of Agriculture

Author : Anonim
Publisher : Unknown
Page : 730 pages
File Size : 45,8 Mb
Release : 1999
Category : Agriculture
ISBN : UOM:39015055285004

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Bibliography of Agriculture by Anonim Pdf

High Pressure NMR

Author : Jiri Jonas
Publisher : Springer Science & Business Media
Page : 272 pages
File Size : 48,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642759260

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High Pressure NMR by Jiri Jonas Pdf

In recent years, there has been a major expansion of high pressure research providing unique information about systems of interest to a wide range of scientific disciplines. Since nuclear magnetic resonance has been applied to a wide spec trum of problems in chemistry, physics and biochemistry, it is not surprising to find that high pressure NMR techniques have also had many applications in these fields of science. Clearly, the high information content of NMR experiments combined with high pressure provides a powerful tool in modern chem istry. It is the aim of this monograph, in the series on NMR Basic Principles and Progress, to illustrate the wide range of prob lems which can be successfully studied by high pressure NMR. Indeed, the various contributions in this volume discuss studies of interest to physics, chemical physics, biochemistry, and chemical reaction kinetics. In many different ways, this monograph demonstrates the power of modern experimental and theoretical techniques to investigate very complex systems. The first contribution, by D. Brinkman, deals with NMR and NQR studies of superionic conductors and high-Tc supercon ductors at high pressure. Pressure effects on phase transitions, detection of new phases, and pressure effects on diffusion and spin-lattice relaxation, represent a few of the topics discussed in this contribution of particular interest to solid state physics.