Glioma Imaging

Author : Whitney B. Pope
Publisher : Springer Nature
Page : 286 pages
File Size : 48,8 Mb
Release : 2019-11-11
Category : Medical
ISBN : 9783030273590

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Glioma Imaging by Whitney B. Pope Pdf

This book covers physiologic, metabolic and molecular imaging for gliomas. Gliomas are the most common primary brain tumors. Imaging is critical for glioma management because of its ability to noninvasively define the anatomic location and extent of disease. While conventional MRI is used to guide current treatments, multiple studies suggest molecular features of gliomas may be identified with noninvasive imaging, including physiologic MRI and amino acid positron emission tomography (PET). These advanced imaging techniques have the promise to help elucidate underlying tumor biology and provide important information that could be integrated into routine clinical practice. The text outlines current clinical practice including common scenarios in which imaging interpretation impacts patient management. Gaps in knowledge and potential areas of advancement based on the application of more experimental imaging techniques will be discussed. In reviewing this book, readers will learn: current standard imaging methodologies used in clinical practice for patients undergoing treatment for glioma and the implications of emerging treatment modalities including immunotherapy the theoretical basis for advanced imaging techniques including diffusion and perfusion MRI, MR spectroscopy, CEST and amino acid PET the relationship between imaging and molecular/genomic glioma features incorporated in the WHO 2016 classification update and the potential application of machine learning about the recently adopted and FDA approved standard brain tumor protocol for multicenter drug trials of the gaps in knowledge that impede optimal patient management and the cutting edge imaging techniques that could address these deficits

Author : Elke Hattingen,Ulrich Pilatus
Publisher : Springer
Page : 161 pages
File Size : 46,7 Mb
Release : 2015-09-02
Category : Medical
ISBN : 9783642450402

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Brain Tumor Imaging by Elke Hattingen,Ulrich Pilatus Pdf

This book describes the basics, the challenges and the limitations of state of the art brain tumor imaging and examines in detail its impact on diagnosis and treatment monitoring. It opens with an introduction to the clinically relevant physical principles of brain imaging. Since MR methodology plays a crucial role in brain imaging, the fundamental aspects of MR spectroscopy, MR perfusion and diffusion-weighted MR methods are described, focusing on the specific demands of brain tumor imaging. The potential and the limits of new imaging methodology are carefully addressed and compared to conventional MR imaging. In the main part of the book, the most important imaging criteria for the differential diagnosis of solid and necrotic brain tumors are delineated and illustrated in examples. A closing section is devoted to the use of MR methods for the monitoring of brain tumor therapy. The book is intended for radiologists, neurologists, neurosurgeons, oncologists and other scientists in the biomedical field with an interest in neuro-oncology.

Author : James Markert
Publisher : Jones & Bartlett Learning
Page : 348 pages
File Size : 54,5 Mb
Release : 2005
Category : Brain Neoplasms
ISBN : 0763726400

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Glioblastoma Multiforme by James Markert Pdf

Treatment of malignant glioma remains a major challenge for neurosurgeons, neurologists, medical oncologists, and radiation oncologists caring for patients with these tumors. Glioblastoma multiforme, the most common type of brain tumor, is also the most deadly -- only five percent of patients or fewer will be alive at five years after diagnosis. This comprehensive new reference is edited by a renowned team consisting of a neurosurgeon, medical oncologist, oncologic surgeon, and radiation oncologist. The book provides basic researchers and clinicians with a contemporary review of the epidemiology, diagnosis, and treatment of glioblastoma multiforme, and also imparts to experienced investigators outside of the field sufficient background to apply their skills to the treatment of this deadly disease. Expert malignant glioma researchers and clinicians provide state-of-the-art chapters on important topics such as molecular genetic classification of glioblastoma, surgical management, stem cell therapy, chemotherapy, angiogenesis, and more.

Author : Juerg Hodler,Rahel A. Kubik-Huch,Gustav K. von Schulthess
Publisher : Springer Nature
Page : 252 pages
File Size : 49,9 Mb
Release : 2020-02-14
Category : Medical
ISBN : 9783030384906

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Diseases of the Brain, Head and Neck, Spine 2020–2023 by Juerg Hodler,Rahel A. Kubik-Huch,Gustav K. von Schulthess Pdf

This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Author : Tommaso Scarabino
Publisher : Springer Science & Business Media
Page : 201 pages
File Size : 55,9 Mb
Release : 2012-03-12
Category : Medical
ISBN : 9788847023703

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Imaging Gliomas After Treatment by Tommaso Scarabino Pdf

This atlas is a detailed guide to the imaging appearances of gliomas following treatment with neurosurgery, radiation therapy, and chemotherapy. Normal and pathological findings are displayed in detailed MR images that illustrate the potential modifications due to treatment. Particular emphasis is placed on characteristic appearances on the newer functional MR imaging techniques, including MR spectroscopy, diffusion-weighted imaging, and perfusion imaging. These techniques are revolutionizing neuroradiology by going beyond the demonstration of macroscopic alterations to the depiction of preceding metabolic changes at the cellular and subcellular level, thereby allowing earlier and more specific diagnosis. A key section comprising some 40 clinical cases and more than 500 illustrations offers an invaluable clinical and research tool not only for neuroradiologists but also for neurosurgeons, radiotherapists, and medical oncologists.

Author : Tommaso Scarabino,Saverio Pollice
Publisher : Springer Nature
Page : 254 pages
File Size : 44,8 Mb
Release : 2019-12-13
Category : Medical
ISBN : 9783030312107

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Imaging Gliomas After Treatment by Tommaso Scarabino,Saverio Pollice Pdf

This book illustrates the characteristics of imaging after treatment in brain gliomas. It describes in detail the modifications to brain tissue, both healthy and pathological, that can manifest after surgery, radiotherapy or chemotherapy treatment. These modifications are discussed in terms of both how they occur in the immediate post-treatment period, and in the long term. The imaging methods used include CT with and without the addition of contrast medium, but above all MRI, which involves the use of routine basic sequences and mainly advanced study techniques such as diffusion, perfusion, spectroscopy and cortical activation. The aim of the text is to equip neuroradiologists with adequate expertise in post-treatment examinations reporting, allowing them to perform an effective differential diagnosis between the persistency or recurrence of illness and the effects of short or long-term treatment. The book is divided into a general section, which addresses the classification of cerebral tumors, the surgical treatment options, radiotherapy and chemotherapy protocols; and a section on clinical cases that employs rich iconography, making it quick and easy to consult. This second edition has been updated to reflect the new WHO classification system from 2016; new surgical, radiotherapy and chemotherapeutic treatment options; and (in the iconography section) the new sequences available from the manufacturers of RM scanners.

Author : Rivka R. Colen
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 55,9 Mb
Release : 2016-10-15
Category : Medical
ISBN : 9780323459761

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Imaging of Brain Tumors, An Issue of Magnetic Resonance Imaging Clinics of North America, by Rivka R. Colen Pdf

This issue of MRI Clinics of North America focuses on Imaging of Brain Tumors, and is edited by Dr. Rivka Colen. Articles will include: Multiparametric Imaging Analysis: MR Spectroscopy; Genomics and MicroRNAs in Glioma; Metabolomics and Hyperpolarization MRI in Brain Tumors; Imaging Genomics in Glioma; Radiomics and Big Data in Imaging; RANO Criteria and Clinical Endpoints; Gliomas: The New WHO Brain Tumor Pathological/Molecular Classification and Clinical and Radiographic Classifications; Liposomal Contrast Agents and Nanoparticles in Brain Tumor Imaging; Multiparametric Imaging Analysis: Perfusion, and more!

Author : Han Zhang,Yanmei Tie,Cornelia Brendle
Publisher : Frontiers Media SA
Page : 111 pages
File Size : 46,9 Mb
Release : 2022-02-01
Category : Medical
ISBN : 9782889741991

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Advanced Imaging of Glioma by Han Zhang,Yanmei Tie,Cornelia Brendle Pdf

Author : Tone Frost Bathen
Publisher : Frontiers Media SA
Page : 165 pages
File Size : 43,7 Mb
Release : 2023-06-08
Category : Science
ISBN : 9782832525555

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Use Of Cancer Imaging In Assessing Glioma Patients by Tone Frost Bathen Pdf

Author : M. Westphal,J.-C. Tonn,Z. Ram
Publisher : Springer Science & Business Media
Page : 204 pages
File Size : 49,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709160909

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Local Therapies for Glioma by M. Westphal,J.-C. Tonn,Z. Ram Pdf

In addition to surgery and radiotherapy, local treatment modalities for the management of brain tumours are increasingly being developed and clinically tested. This book describes for the first time basic tumour biology as well as all current procedures in progress at the most recent level of knowledge, presented by leading experts in the respective fields. Image guided resection procedures, fluorescence guided surgery, developments in interstitial radiosurgery are addressed, just as intracavitary chemotherapy and all current concepts and studies of interstitial targeted therapy. Owing to its topicality this book will remain for long the standard for this comprehensively treated subject.

Author : Michael E. Sughrue,Isaac Yang
Publisher : Academic Press
Page : 256 pages
File Size : 40,7 Mb
Release : 2019-08-03
Category : Medical
ISBN : 9780128136348

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New Techniques for Management of ‘Inoperable’ Gliomas by Michael E. Sughrue,Isaac Yang Pdf

New Techniques for Management of 'Inoperable' Gliomas radically challenges the assumption that certain gliomas cannot be removed with modern techniques, contesting stereotypical thinking and establishing new paradigms in the field. Gliomas are primary brain tumors which are often fatal. Recent data has demonstrated that despite the fact that surgery cannot cure gliomas, patient survival is substantially improved by removing as much of the tumor as possible. This fact has raised the imperative that neurologists try to improve techniques to bring surgical resection to as many patients as possible. This book brings new insights and technologies to the forefront, giving hope to patients. Provides the first comprehensive book to discuss techniques for removing gliomas that are traditionally deemed ‘inoperable’ Presents a great reference tool that challenges stereotypical thinking by offering techniques by innovative surgeons Includes chapters that are organized by different glioma types and surgery/techniques

Author : Allan H. Friedman
Publisher : Cambridge University Press
Page : 237 pages
File Size : 47,8 Mb
Release : 2016-03-31
Category : Medical
ISBN : 9781107065970

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The Duke Glioma Handbook by Allan H. Friedman Pdf

Provides a summary of glioma biology, genetics and management, based on the world-leading Duke University Preston Robert Tisch Brain Tumor Center program.

Author : Ruijiang Li,Lei Xing,Sandy Napel,Daniel L. Rubin
Publisher : CRC Press
Page : 420 pages
File Size : 49,5 Mb
Release : 2019-07-09
Category : Science
ISBN : 9781351208260

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Radiomics and Radiogenomics by Ruijiang Li,Lei Xing,Sandy Napel,Daniel L. Rubin Pdf

Radiomics and Radiogenomics: Technical Basis and Clinical Applications provides a first summary of the overlapping fields of radiomics and radiogenomics, showcasing how they are being used to evaluate disease characteristics and correlate with treatment response and patient prognosis. It explains the fundamental principles, technical bases, and clinical applications with a focus on oncology. The book’s expert authors present computational approaches for extracting imaging features that help to detect and characterize disease tissues for improving diagnosis, prognosis, and evaluation of therapy response. This book is intended for audiences including imaging scientists, medical physicists, as well as medical professionals and specialists such as diagnostic radiologists, radiation oncologists, and medical oncologists. Features Provides a first complete overview of the technical underpinnings and clinical applications of radiomics and radiogenomics Shows how they are improving diagnostic and prognostic decisions with greater efficacy Discusses the image informatics, quantitative imaging, feature extraction, predictive modeling, software tools, and other key areas Covers applications in oncology and beyond, covering all major disease sites in separate chapters Includes an introduction to basic principles and discussion of emerging research directions with a roadmap to clinical translation

Author : A.B.M.F. Karim,Edward R. Jr. Laws
Publisher : Springer Science & Business Media
Page : 292 pages
File Size : 55,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642841279

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Glioma by A.B.M.F. Karim,Edward R. Jr. Laws Pdf

Many recent developments in neuro-oncology relevant to clinical practice have contributed to improved patient care. The most im portant impact of these developments on treatment may have been a change in the attitudes of the neuro-oncologists involved in making decisions regarding patients with gliomas. From an era of uncertainty which led to therapeutic nihilism, we have entered one of active interventions based on objective parameters for the treat ment of gliomas, which may be either slow-growing or rapid kil lers. The histopathological characteristics of gliomatous lesions are intriguing, and it is only recently that a clearer picture has begun to emerge. A group of dedicated neuropathologists has been at tempting to reach a consensus on pathological classification and grading, providing an important landmark in the field of neuro oncology. This book does not mean to provide exhaustive details on the histopathology of gliomas, but rather highlights the main problems in an authoritative chapter. This chapter attempts to guide the reader to a better understanding of all aspects of the neuropathology of glioma. Neuroradiology has recently seen several breakthroughs. Im ages unimaginable a decade ago are now providing us with an al most three-dimensional impression. But the concomitant illusions and artifacts must also be kept in mind, and pragmatic ideas are carefully put forward in this book about the developing body of knowledge concerning the newer imaging techniques.

Author : M.A. Hayat
Publisher : Springer Science & Business Media
Page : 449 pages
File Size : 52,7 Mb
Release : 2011-04-03
Category : Medical
ISBN : 9789400706187

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Tumors of the Central Nervous System, Volume 2 by M.A. Hayat Pdf

Advantages and limitations of biomarkers in gliomagenesis are described. Molecular subtypes of gliomas are detailed. The role played by TP53 gene mutation in the deadliest brain tumor, glioblastoma multiforme, is pointed out. The role of mutations of IDH1 and IDH2, and isocitrate dehydrogenases in malignant gliomas are presented. Metabolic differences in different regions of the glioma tumor are clarified. Various types of imaging modalities, including PET and SPECT, to diagnose gliomas in general and glioblastoma in particular in patients are explained in detail. Both low-grade and high-grade gliomas are discussed. Conventional as well as fluorescent-guided resection techniques for high-grade, recurrent malignant gliomas are detailed. Impact of resection extent on outcomes in patients with high-grade gliomas is clarified. The advantage of the use of intraoperative low-field MRI in glioma surgery is explained.