Glycoscience

Glycoscience Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Glycoscience book. This book definitely worth reading, it is an incredibly well-written.

Transforming Glycoscience

National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Assessing the Importance and Impact of Glycomics and Glycosciences
Transforming Glycoscience Book PDF

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Assessing the Importance and Impact of Glycomics and Glycosciences
Publisher : National Academies Press
Page : 171 pages
File Size : 55,8 Mb
Release : 2012-10-23
Category : Science
ISBN : 9780309260862

Get Book

Transforming Glycoscience by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Assessing the Importance and Impact of Glycomics and Glycosciences Pdf

A new focus on glycoscience, a field that explores the structures and functions of sugars, promises great advances in areas as diverse as medicine, energy generation, and materials science, this report finds. Glycans-also known as carbohydrates, saccharides, or simply as sugars-play central roles in many biological processes and have properties useful in an array of applications. However, glycans have received little attention from the research community due to a lack of tools to probe their often complex structures and properties. Transforming Glycoscience: A Roadmap for the Future presents a roadmap for transforming glycoscience from a field dominated by specialists to a widely studied and integrated discipline, which could lead to a more complete understanding of glycans and help solve key challenges in diverse fields.

Comprehensive Glycoscience

Anonim
Comprehensive Glycoscience Book PDF

Author : Anonim
Publisher : Elsevier
Page : 0 pages
File Size : 42,5 Mb
Release : 2021-06-21
Category : Science
ISBN : 9780128222447

Get Book

Comprehensive Glycoscience by Anonim Pdf

Comprehensive Glycoscience, Second Edition, Five Volume Set assembles the top minds in this area who provide an update on the renowned 2007 first edition, including new discoveries and latest advances in glycoscience-related research areas such as glycan microarrays, carbohydrate materials, glycoengineering and microbiome research. The result is an up-to-date work which will impress readers with the many new advances that are outlined and taught in this second edition. Most areas of the original edition have been majorly updated, some overlapping topics have been consolidated, and several topics have been rearranged into more appropriate sections. Combines multiple aspects of glycoscience in one comprehensive and reliable reference work Includes all major developments since 2007 (e.g. nanotechnology) Places glycoscience at the crossroads of several disciplines, including biology, biochemistry, glycobiology and synthetic chemistry, thus offering a truly interdisciplinary perspective

Glycoscience: Chemistry and Chemical Biology I–III

Bertram O. Fraser-Reid,Kuniaki Tatsuta,Joachim Thiem
Glycoscience Chemistry and Chemical Biology I III Book PDF

Author : Bertram O. Fraser-Reid,Kuniaki Tatsuta,Joachim Thiem
Publisher : Springer Science & Business Media
Page : 2817 pages
File Size : 52,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642568749

Get Book

Glycoscience: Chemistry and Chemical Biology I–III by Bertram O. Fraser-Reid,Kuniaki Tatsuta,Joachim Thiem Pdf

Glycostructures play a highly diverse and crucial role in a myriad of organisms and systems in biology, physiology, medicine, and bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and chemistry behind them. In this set the editors present up-to-date information on glycostructures, their chemistry and chemical biology, in the form of a comprehensive survey. The text is accompanied by over 2000 figures, chemical structures and reaction schemes and more than 9000 references. The accompanying CD-ROM enables, besides text searches, searches for structures, schemes, and other information.

Glycoscience: Biology and Medicine

Naoyuk Taniguchi,Tamao Endo,Gerald W. Hart,Peter H. Seeberger,Chi-Huey Wong
Glycoscience Biology and Medicine Book PDF

Author : Naoyuk Taniguchi,Tamao Endo,Gerald W. Hart,Peter H. Seeberger,Chi-Huey Wong
Publisher : Springer
Page : 0 pages
File Size : 46,7 Mb
Release : 2014-11-14
Category : Science
ISBN : 4431548408

Get Book

Glycoscience: Biology and Medicine by Naoyuk Taniguchi,Tamao Endo,Gerald W. Hart,Peter H. Seeberger,Chi-Huey Wong Pdf

The aim of the book is to provide a succinct overview of the current status of glycoscience from both basic biological and medical points of view and to propose future directions, in order to facilitate further integrations of glycoscience with other fields in biological and medical studies. Glycans (carbohydrate oligomers) are the so-called “building blocks” of carbohydrates, nucleic acids, proteins and lipids and play major roles in many biological phenomena as well as in various pathophysiological processes. However, this area of glycoscience has been neglected from the research community because glycan structures are very complex and functionally diverse and as compared to proteins and nucleic acids simple tools for the amplification, sequencing and auto-synthesis of glycans are not available. Many scientists in other fields of research have now realized that glycosylation, i.e. the addition of glycans to a protein backbone, is the most abundant post translational modification reactions and is an important field of research and sometimes they require a glycobiology and/or glycochemistry approach to be used. It is still difficult, however, for non-expert researchers to use these techniques. This book provides numerous but simple overviews of current topics and protocols for the experiments. The book is aimed at university students and above, including non-experts in the field of glycoscience.

Essentials of Glycobiology

Ajit Varki,Maarten J. Chrispeels
Essentials of Glycobiology Book PDF

Author : Ajit Varki,Maarten J. Chrispeels
Publisher : CSHL Press
Page : 694 pages
File Size : 43,9 Mb
Release : 1999
Category : Medical
ISBN : 0879696818

Get Book

Essentials of Glycobiology by Ajit Varki,Maarten J. Chrispeels Pdf

Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Glycoscience

Bertram O. Fraser-Reid,Kuniaki Tatsuta,Joachim Thiem
Glycoscience Book PDF

Author : Bertram O. Fraser-Reid,Kuniaki Tatsuta,Joachim Thiem
Publisher : Springer Science & Business Media
Page : 2847 pages
File Size : 48,5 Mb
Release : 2008-04-14
Category : Science
ISBN : 9783540361541

Get Book

Glycoscience by Bertram O. Fraser-Reid,Kuniaki Tatsuta,Joachim Thiem Pdf

As a reflection of the quantum leap that has been made in the study of glycostructures, the first edition of this book has been completely revised and updated. The editors give up-to-date information on glycostructures, their chemistry and chemical biology in the form of a completely comprehensive survey. Glycostructures play highly diverse and crucial roles in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and the chemistry behind them. While many facts remain undiscovered, this MRW has been contributed to by a large number of the world’s leading researchers in the field.

Click Chemistry in Glycoscience

Zbigniew J. Witczak,Roman Bielski
Click Chemistry in Glycoscience Book PDF

Author : Zbigniew J. Witczak,Roman Bielski
Publisher : John Wiley & Sons
Page : 402 pages
File Size : 50,9 Mb
Release : 2013-03-18
Category : Science
ISBN : 9781118275337

Get Book

Click Chemistry in Glycoscience by Zbigniew J. Witczak,Roman Bielski Pdf

Lays the foundation for new methods and applications of carbohydrate click chemistry Introduced by K. Barry Sharpless of The Scripps Research Institute in 2001, click chemistry mimics nature, giving researchers the tools needed to generate new substances quickly and reliably by joining small units together. With contributions from more than thirty pioneering researchers in the field, this text explores the many promising applications of click chemistry in glycoscience. Readers will learn both the basic concepts of carbohydrate click chemistry as well as its many biomedical applications, including synthetic antigens, analogs of cell-surface receptors, immobilized enzymes, targeted drug delivery systems, and multivalent cancer vaccines. Click Chemistry in Glycoscience examines a broad range of methodologies and strategies that have emerged from this rapidly evolving field. Each chapter describes new approaches, ideas, consequences, and applications resulting from the introduction of click processes. Divided into four sections, the book covers: Click chemistry strategies and decoupling Thio-click chemistry of carbohydrates Carbohydrate click chemistry for novel synthetic targets Carbohydrate click chemistry in biomedical sciences Thoroughly researched, the book reflects the most recent findings published in the literature. Diagrams and figures throughout the book enable readers to more easily grasp complex concepts and reaction processes. At the end of each chapter, references lead to the primary literature for further investigation of individual topics. The application of click chemistry to carbohydrates has tremendous implications for research. With this book as their guide, researchers have a solid foundation from which they can develop new methods and applications of carbohydrate click chemistry, including new carbohydrate-based therapeutics.

NMR in Glycoscience and Glycotechnology

Koichi Kato,Thomas Peters
NMR in Glycoscience and Glycotechnology Book PDF

Author : Koichi Kato,Thomas Peters
Publisher : Royal Society of Chemistry
Page : 402 pages
File Size : 52,6 Mb
Release : 2017-05-15
Category : Science
ISBN : 9781782623946

Get Book

NMR in Glycoscience and Glycotechnology by Koichi Kato,Thomas Peters Pdf

This volume focuses on solution and solid-state NMR of carbohydrates, glycoproteins, glyco-technologies, biomass and related topics. It is estimated that at least 80% of all proteins are glycoproteins. Because of the complexity, heterogeneity and flexibility of the sugar chains, the structural biology approaches for glycoconjugates have been generally avoided. NMR techniques although well established for structural analyses of proteins and nucleic acids, cannot be simply applied to this complex class of biomolecules. Nonetheless, recently developed NMR techniques for carbohydrates open the door to conformational studies of a variety of sugar chains of biological interest. NMR studies on glycans will have significant impact on the development of vaccines, adjuvants, therapeutics, biomarkers and on biomass regeneration. In this volume, the Editors have collected the most up-to-date NMR applications from experts in the field of carbohydrate NMR spectroscopy. Timely and useful, not only for NMR specialists, it will appeal to researchers in the general field of structural biology, biochemistry and biophysics, molecular and cellular biology and material science.

Transforming Glycoscience

National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Assessing the Importance and Impact of Glycomics and Glycosciences
Transforming Glycoscience Book PDF

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Assessing the Importance and Impact of Glycomics and Glycosciences
Publisher : National Academies Press
Page : 171 pages
File Size : 40,5 Mb
Release : 2012-11-23
Category : Science
ISBN : 9780309260831

Get Book

Transforming Glycoscience by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Assessing the Importance and Impact of Glycomics and Glycosciences Pdf

A new focus on glycoscience, a field that explores the structures and functions of sugars, promises great advances in areas as diverse as medicine, energy generation, and materials science, this report finds. Glycans-also known as carbohydrates, saccharides, or simply as sugars-play central roles in many biological processes and have properties useful in an array of applications. However, glycans have received little attention from the research community due to a lack of tools to probe their often complex structures and properties. Transforming Glycoscience: A Roadmap for the Future presents a roadmap for transforming glycoscience from a field dominated by specialists to a widely studied and integrated discipline, which could lead to a more complete understanding of glycans and help solve key challenges in diverse fields.

Experimental Glycoscience

Naoyuki Taniguchi,Akemi Suzuki,Yukishige Ito,Hisashi Narimatsu,Toshisuke Kawasaki,Sumihiro Hase
Experimental Glycoscience Book PDF

Author : Naoyuki Taniguchi,Akemi Suzuki,Yukishige Ito,Hisashi Narimatsu,Toshisuke Kawasaki,Sumihiro Hase
Publisher : Springer Science & Business Media
Page : 255 pages
File Size : 46,8 Mb
Release : 2009-03-08
Category : Science
ISBN : 9784431779247

Get Book

Experimental Glycoscience by Naoyuki Taniguchi,Akemi Suzuki,Yukishige Ito,Hisashi Narimatsu,Toshisuke Kawasaki,Sumihiro Hase Pdf

The aim of this book is to provide experimental protocols covering many aspects of glycobiology, glycotechnology, and chemistry: biochemistry, molecular and cellular biology, genetics, physiology, and medicine. The protocols are all self-contained descriptions of the equipment and reagents needed, followed by details of the experimental procedure. In the post-genomic era, glycobiology is coming of age because more than half of proteins are glycosylated and the importance of sugar chains in various fields of life science research cannot be disregarded. Many scientists had not entered this area because glycobiology and glycoscience used to be considered difficult fields. This book, therefore, is presented much like a cookbook which can help scientists in fields other than glycobiology and glycoscience carry out research more easily.

Glycoscience

Joachim Thiem,Hugues Driguez
Glycoscience Book PDF

Author : Joachim Thiem,Hugues Driguez
Publisher : Springer Science & Business Media
Page : 264 pages
File Size : 42,7 Mb
Release : 1997
Category : Carbohydrates
ISBN : 3540620338

Get Book

Glycoscience by Joachim Thiem,Hugues Driguez Pdf

Annotation This book presents the state of the art in the synthesis very complex saccharide structures, written by leading scientists at the forefront of this rapidly growing field. Reflecting the particular significance in recent years of efficient and selective procedures employing enzymes for preparative purposes in the carbohydrate field, a major proportion of the articles focus on these biocatalytic methods. In addition, recent strategies for the construction of unusual carbohydrates structures employing novel and creative methodologies are highlighted. Further, particular emphasis is placed on very complex saccharide structures as well as on special solutions to problems that are particularly challenging.

Glycoscience: Basic Science to Applications

Naoyuki Taniguchi,Tamao Endo,Jun Hirabayashi,Shoko Nishihara,Kenji Kadomatsu,Kazunari Akiyoshi,Kiyoko F. Aoki-Kinoshita
Glycoscience Basic Science to Applications Book PDF

Author : Naoyuki Taniguchi,Tamao Endo,Jun Hirabayashi,Shoko Nishihara,Kenji Kadomatsu,Kazunari Akiyoshi,Kiyoko F. Aoki-Kinoshita
Publisher : Springer Nature
Page : 405 pages
File Size : 42,6 Mb
Release : 2019-09-12
Category : Medical
ISBN : 9789811358562

Get Book

Glycoscience: Basic Science to Applications by Naoyuki Taniguchi,Tamao Endo,Jun Hirabayashi,Shoko Nishihara,Kenji Kadomatsu,Kazunari Akiyoshi,Kiyoko F. Aoki-Kinoshita Pdf

This book presents the state of the art in glycoscience and proposes a road map for the coming decade, focusing on the potential of glycoscience research to shed light on important basic science issues and give rise to exciting new applications, especially in the field of diagnosis and therapeutics. Individual sections offer in-depth coverage of various topics relating to glycans and biopharmaceuticals, glycans in medical science and medicine, glycan technologies, glycans in food and nutrients, and glycan-related materials and their uses. In addition, the book presents an exemplary training course on glycomics and highlights educational and analytical web resources, and also includes glossaries and boxes summarizing key facts to ensure ease of understanding for non-expert readers and students. Written by more than 150 active participants in the Japan Consortium for Glycobiology and Glycotechnology (JCGG), whose goal is to promote the development of interdisciplinary glycoscience and establish a global network in the field, it is a valuable resource for students, postdocs, and researchers in the life sciences as well as for stakeholders and professionals in government, funding agencies and industry.

The Role of Glycosylation in Health and Disease

Gordan Lauc,Irena Trbojević-Akmačić
The Role of Glycosylation in Health and Disease Book PDF

Author : Gordan Lauc,Irena Trbojević-Akmačić
Publisher : Springer Nature
Page : 392 pages
File Size : 48,6 Mb
Release : 2021-09-08
Category : Science
ISBN : 9783030701154

Get Book

The Role of Glycosylation in Health and Disease by Gordan Lauc,Irena Trbojević-Akmačić Pdf

Glycobiology is an emerging field of studying glycans (sugars) and glycoconjugates that are essentially involved in almost all biological processes, from fine-tuning glycoprotein function to protein-protein interactions, signaling, immune response, host-pathogen interactions, etc. However, due to structural complexity of glycans and analytical challenges this exciting field was lagging behind other areas of biology. With technological advancements growing number of glycans’ functions are being discovered and the study of glycans is becoming a cutting-edge discipline in basic and clinical research. Despite recent developments in glycobiology field, many aspects of glycosylation process still remain unknown, both in a healthy human organism and in pathological states. Human glycome is dynamic and changes with physiological triggers, immune challenges and disease. Atypical glycosylation is consequently a subject of disease biomarker research, and a target for therapeutic interventions. On the other hand, properties of glycosylated biotherapeutics are predominantly determined by their glycans. The Role of Glycosylation in Health and Disease provides a comprehensive overview of types and functions of glycans in a healthy human organism as well as their role in pathophysiology of different diseases and efficiency of glycosylated biotherapeutics. Written by the experts in the field, this book aims to bring glycobiology field closer to students, researchers in life sciences and professionals in biopharmaceutical industry.

Glycoscience and Microbial Adhesion

Thisbe K. Lindhorst,Stefan Oscarson,Julie Bouckaert
Glycoscience and Microbial Adhesion Book PDF

Author : Thisbe K. Lindhorst,Stefan Oscarson,Julie Bouckaert
Publisher : Springer Science & Business Media
Page : 194 pages
File Size : 40,5 Mb
Release : 2009-06-23
Category : Science
ISBN : 9783642013034

Get Book

Glycoscience and Microbial Adhesion by Thisbe K. Lindhorst,Stefan Oscarson,Julie Bouckaert Pdf

bacterial carbohydrate recognition are conveyed, covering Gram-positive as well as Gram-negative bacteria, in Chapter 4 Streptococci and Staphylococci, and in Chapter 5, carbohydrate binding specificities of Helicobacter pylori. In Chapter 6, "Bitter sweetness of complexity," the collected reflections on mic- bial adhesion are expanded by a perspective on a broader impact of glycosylation on cellular adhesion, motility and regulatory processes, paralleling the complexity of N-glycan structures on cell surfaces. It highlights particularly how structural details of N-glycans have been causally related to pathological scenarios, with a focus on ?(1,6)-N-acetylglucosaminyltransferase. In the final chapter, biofilm formation is reviewed, covering knowledge about structure and biosynthesis of polysaccharide intercellular adhesins (PIAs) which are central to biofilm formation. This comprehensive chapter explains all PIA-related principles of medical device-associated infections. It is our hope, that this collection of expert articles, ranging from structural ch- istry and structural biology to biochemistry and medicine, will be a stimulation and motivation for our colleagues in the life sciences. At the same time, we hope that these reflections on microbial adhesion will awake interest in and promote und- standing of the complex processes associated with the glycocalyx and the multif- eted interactions between the host cell and its "guest," as well as the biological consequences resulting from this mutual interplay.

Domino and Intramolecular Rearrangement Reactions as Advanced Synthetic Methods in Glycoscience

Zbigniew J. Witczak,Roman Bielski
Domino and Intramolecular Rearrangement Reactions as Advanced Synthetic Methods in Glycoscience Book PDF

Author : Zbigniew J. Witczak,Roman Bielski
Publisher : John Wiley & Sons
Page : 368 pages
File Size : 54,7 Mb
Release : 2016-01-07
Category : Science
ISBN : 9781119044239

Get Book

Domino and Intramolecular Rearrangement Reactions as Advanced Synthetic Methods in Glycoscience by Zbigniew J. Witczak,Roman Bielski Pdf

The book consists of a brief introduction, a foreward provided byprofessor Danishefsky of Columbia University, and about 14 –16 chapters, each written by one or two eminent scholars/authorsdescribing their recent research in the area of either dominoreactions or intramolecular rearrangements in carbohydratechemistry. Three or four chapters will be reviews. The domino (cascade, tandem)reactions are always intramolecular. They are usually very fast,clean and offer highly complex structures in a one pot process.Intramolecular rearrangements offer very similar advantages andoften lead to highly complex products as well. Although manyrecently isolated carbohydrates fulfill various sophisticatedfunctions, their structures are often very complex. The editorscover the broadest scope of novel methodologies possible. All thesynthetic and application aspects of domino/cascade reactions areexplored in this book. A second theme that will be covered isintramolecular rearrangement, which is also fast, stereoselective,and often constitutes one or more steps of domino /cascade process.Selected examples of intramolecular rearrangements are presented.Together, both processes offer an elegant and convenient approach to the synthesis of many complex molecules,which are normally difficult to synthesize via alternative routes.It appears that domino and intramolecular rearrangements areideally suited to synthesize certain specific modifiedmonosaccharides. What is particularly important is that bothprocesses are intermolecular and almost always yield products withvery well-defined stereochemistry. This high definition isabsolutely crucial when synthesizing advanced, modified mono andoligosaccharides. The choice of contributors reflects anemphasis on both therapeutic and pharmacological aspects of carbohydratechemistry.