Growth Regulation Carcinogenesis

Author : Walter R. Paukovits
Publisher : CRC Press
Page : 518 pages
File Size : 41,5 Mb
Release : 2020-01-29
Category : Science
ISBN : 9781351089210

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Growth Regulation and Carcinogenesis by Walter R. Paukovits Pdf

Growth Regulation and Carcinogenesis discusses topics such as growth factors, including stimulators and inhibitors of proliferation; networks in proliferation regulation; differentiation-inducing factors; origins of neoplasia and their relationship to growth control; genetic alterations in cellular regulatory machinery; extrachromosomal phenomena; non-genotoxic carcinogens; immortalization and transformation of cells; and the role of cell production, cell function, and cell elimination in physiological growth control.

Author : Walter R. Paukovits
Publisher : CRC Press
Page : 338 pages
File Size : 46,6 Mb
Release : 1990-12-19
Category : Medical
ISBN : UOM:39015019565541

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Growth Regulation & Carcinogenesis by Walter R. Paukovits Pdf

Growth Regulation and Carcinogenesis discusses topics such as growth factors, including stimulators and inhibitors of proliferation; networks in proliferation regulation; differentiation-inducing factors; origins of neoplasia and their relationship to growth control; genetic alterations in cellular regulatory machinery; extrachromosomal phenomena; non-genotoxic carcinogens; immortalization and transformation of cells; and the role of cell production, cell function, and cell elimination in physiological growth control.

Author : Walter R. Paukovits
Publisher : Unknown
Page : 128 pages
File Size : 55,7 Mb
Release : 2018
Category : Cancer cells
ISBN : 1351097679

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Growth Regulation and Carcinogenesis by Walter R. Paukovits Pdf

"Growth Regulation and Carcinogenesis discusses topics such as growth factors, including stimulators and inhibitors of proliferation; networks in proliferation regulation; differentiation-inducing factors; origins of neoplasia and their relationship to growth control; genetic alterations in cellular regulatory machinery; extrachromosomal phenomena; non-genotoxic carcinogens; immortalization and transformation of cells; and the role of cell production, cell function, and cell elimination in physiological growth control."--Provided by publisher.

Author : S. Papa,D. Kanduc,J.M. Tager
Publisher : Birkhäuser
Page : 315 pages
File Size : 47,6 Mb
Release : 2013-03-11
Category : Medical
ISBN : 9783034889506

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Cell Growth and Oncogenesis by S. Papa,D. Kanduc,J.M. Tager Pdf

Rapid progress has been made in our understanding of the molecular mechanisms of cell growth and oncogenesis during the past decade. This book comprises recent results on the regulation of cell growth in normal and neoplastic tissues by growth factors including hormones, and by the activation and inactivation of oncogenes and tumor suppressor genes, respectively. Special attention has been given to the presentation of the frequently neglected close correlation between changes in signal transduction and metabolism pathways during oncogenesis.

Author : Gerard Meurant
Publisher : Elsevier
Page : 402 pages
File Size : 40,7 Mb
Release : 1995-09-27
Category : Science
ISBN : 0080535542

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Liver Regeneration and Carcinogenesis by Gerard Meurant Pdf

Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines. This book brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis, and liver tumor therapy. The contributors are pioneers and leaders in this field. * Logical organization of material in three detailed and comprehensive sections: liver regeneration, liver carcinogenesis, and liver tumor treatment * Contributors are pioneers and leaders in the field * There are currently no books on this subject on the market * Research focus is at the molecular level

Author : Anonim
Publisher : Unknown
Page : 728 pages
File Size : 46,8 Mb
Release : 2010
Category : Government publications
ISBN : UCSD:31822037817723

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How Tobacco Smoke Causes Disease by Anonim Pdf

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Author : Abdel-Majid Khatib
Publisher : Springer Science & Business Media
Page : 161 pages
File Size : 51,9 Mb
Release : 2007-05-01
Category : Medical
ISBN : 9781402051326

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Regulation of Carcinogenesis, Angiogenesis and Metastasis by the Proprotein Convertases (PC's) by Abdel-Majid Khatib Pdf

Convertases are widely expressed activating enzymes involved in various physiological and pathological processes. This book provides detailed and updated information on the role of these molecules in cancer. It is the first to summarize current knowledge of the importance of protein precursors maturation by the convertases in tumor progression, angiogenesis and metastasis. Each chapter discusses the importance of the convertases in the activation of various cancer-related molecules including growth factors, adhesion molecules and proteases.

Author : Marc E. Lippman
Publisher : John Wiley & Sons
Page : 266 pages
File Size : 49,6 Mb
Release : 1988-05-01
Category : Electronic
ISBN : 0471614416

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Growth Regulation of Cancer by Marc E. Lippman Pdf

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 44,5 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Risk Assessment Methodology
Publisher : National Academies Press
Page : 375 pages
File Size : 44,7 Mb
Release : 1993-02-01
Category : Science
ISBN : 9780309047869

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Issues in Risk Assessment by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Risk Assessment Methodology Pdf

The scientific basis, inference assumptions, regulatory uses, and research needs in risk assessment are considered in this two-part volume. The first part, Use of Maximum Tolerated Dose in Animal Bioassays for Carcinogenicity, focuses on whether the maximum tolerated dose should continue to be used in carcinogenesis bioassays. The committee considers several options for modifying current bioassay procedures. The second part, Two-Stage Models of Carcinogenesis, stems from efforts to identify improved means of cancer risk assessment that have resulted in the development of a mathematical dose-response model based on a paradigm for the biologic phenomena thought to be associated with carcinogenesis.

Author : George G. Chen,Paul B.S. Lai
Publisher : Springer Science & Business Media
Page : 305 pages
File Size : 44,5 Mb
Release : 2012-08-28
Category : Medical
ISBN : 9789400749177

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Novel Apoptotic Regulators in Carcinogenesis by George G. Chen,Paul B.S. Lai Pdf

Our recent understanding of the cellular and molecular defects and the regulation of the apoptotic signalling pathways has resulted in rationally designed anticancer strategies and the development of novel agents that regulates apoptosis. A comprehensive review of all apoptotic-related anticancer therapies is not the purpose of this book. However, in the volume of this book with 11 chapters, we have described a number of novel apoptotic regulators that have shown promising value and also great feasibility for cancer treatment. These novel agents either occur naturally or are chemically synthesized. While we are excited about the discovery and development of these novel apoptotic regulators as potential anticancer agents, a degree of caution should be always borne in mind when interpreting the success of preclinical pro-apoptotic candidates since potential problems inevitably lie ahead. These problems usually include target specificity, unanticipated toxicity, compound stability, formulation issues, pharmacokinetic and pharmacodynamic profiles. Nevertheless, we believe that this collection of 11 chapters by established leaders in the area of apoptosis will be of great interest to not only academics working in the field of cancer research and apoptosis but also pharmaceutical and pharmacological industries that . We are looking forward to the further development to push these potential agents toward clinical stage.

Author : Asterios S. Tsiftsoglou
Publisher : Springer
Page : 352 pages
File Size : 46,8 Mb
Release : 1996
Category : Medical
ISBN : UOM:39015040643457

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Tumor Biology by Asterios S. Tsiftsoglou Pdf

Proceedings of the NATO Science Institute "Regulation of Cell Growth, Differentiation and Genetics in Cancer", held at Porto Carras, Halkidiki, Greece, September 1-12, 1995

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 52,7 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : Alecsandru Ioan Baba,Cornel Cătoi
Publisher : Unknown
Page : 787 pages
File Size : 55,5 Mb
Release : 2007
Category : Electronic books
ISBN : 9732714573

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Comparative Oncology by Alecsandru Ioan Baba,Cornel Cătoi Pdf

Author : Gary S. Stein,Arthur B. Pardee
Publisher : John Wiley & Sons
Page : 826 pages
File Size : 48,8 Mb
Release : 2004-05-24
Category : Science
ISBN : 0471250716

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Cell Cycle and Growth Control by Gary S. Stein,Arthur B. Pardee Pdf

This comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3-D color structures and much more.