Handbook Of Tissue Optical Clearing

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Handbook of Tissue Optical Clearing

Valeriĭ Viktorovich Tuchin,Zhu Dan,Elina A. Genina
Handbook of Tissue Optical Clearing Book PDF

Author : Valeriĭ Viktorovich Tuchin,Zhu Dan,Elina A. Genina
Publisher : Unknown
Page : 128 pages
File Size : 41,9 Mb
Release : 2021-11
Category : Imaging systems in medicine
ISBN : 1032118695

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Handbook of Tissue Optical Clearing by Valeriĭ Viktorovich Tuchin,Zhu Dan,Elina A. Genina Pdf

"Biomedical photonics is currently one of the fastest growing fields, connecting research in physics, optics, and electrical engineering coupled with medical and biological applications. It allows for the structural and functional analysis of tissues and cells with resolution and contrast unattainable by any other methods. However, the major challenges of many biophotonics techniques are associated with the need to enhance imaging resolution even further to the sub-cellular level as well as translate them for in vivo studies. The tissue optical clearing method uses immersion of tissues into optical clearing agents (OCAs) that reduces the scattering of tissue and makes tissue more transparent and this method has been successfully used ever since. This book is a self-contained introduction to tissue optical clearing, including the basic principles and in vitro biological applications, from in vitro to in vivo tissue optical clearing methods, and combination of tissue optical clearing and various optical imaging for diagnosis. The chapters cover a wide range of issues related to the field of tissue optical clearing: mechanisms of tissue optical clearing in vitro and in vivo; traditional and innovative optical clearing agents; recent achievements in optical clearing of different tissues (including pathological tissues) and blood for optical imaging diagnosis and therapy. This book provides a comprehensive account of the latest research and possibilities of utilising optical clearing as an instrument for improving the diagnostic effectiveness of modern optical diagnostic methods. The book is addressed to biophysicist researchers, graduate students and postdocs of biomedical specialties, as well as biomedical engineers and physicians interested in the development and application of optical methods in medicine. Key features: The first collective reference to collate all known knowledge on this topic Edited by experts in the field with chapter contributions from subject area specialists Brings together the two main approaches in immersion optical clearing into one cohesive book"--

Handbook of Tissue Optical Clearing

Valery V. Tuchin,Dan Zhu,Elina A. Genina
Handbook of Tissue Optical Clearing Book PDF

Author : Valery V. Tuchin,Dan Zhu,Elina A. Genina
Publisher : CRC Press
Page : 682 pages
File Size : 43,6 Mb
Release : 2022-02-04
Category : Science
ISBN : 9781000466300

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Handbook of Tissue Optical Clearing by Valery V. Tuchin,Dan Zhu,Elina A. Genina Pdf

Biomedical photonics is currently one of the fastest growing fields, connecting research in physics, optics, and electrical engineering coupled with medical and biological applications. It allows for the structural and functional analysis of tissues and cells with resolution and contrast unattainable by any other methods. However, the major challenges of many biophotonics techniques are associated with the need to enhance imaging resolution even further to the sub-cellular level as well as translate them for in vivo studies. The tissue optical clearing method uses immersion of tissues into optical clearing agents (OCAs) that reduces the scattering of tissue and makes tissue more transparent and this method has been successfully used ever since. This book is a self-contained introduction to tissue optical clearing, including the basic principles and in vitro biological applications, from in vitro to in vivo tissue optical clearing methods, and combination of tissue optical clearing and various optical imaging for diagnosis. The chapters cover a wide range of issues related to the field of tissue optical clearing: mechanisms of tissue optical clearing in vitro and in vivo; traditional and innovative optical clearing agents; recent achievements in optical clearing of different tissues (including pathological tissues) and blood for optical imaging diagnosis and therapy. This book provides a comprehensive account of the latest research and possibilities of utilising optical clearing as an instrument for improving the diagnostic effectiveness of modern optical diagnostic methods. The book is addressed to biophysicist researchers, graduate students and postdocs of biomedical specialties, as well as biomedical engineers and physicians interested in the development and application of optical methods in medicine. Key features: The first collective reference to collate all known knowledge on this topic Edited by experts in the field with chapter contributions from subject area specialists Brings together the two main approaches in immersion optical clearing into one cohesive book

Optical Clearing of Tissues and Blood

Valeriĭ Viktorovich Tuchin
Optical Clearing of Tissues and Blood Book PDF

Author : Valeriĭ Viktorovich Tuchin
Publisher : CCH
Page : 274 pages
File Size : 48,7 Mb
Release : 2006
Category : Medical
ISBN : 0819460060

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Optical Clearing of Tissues and Blood by Valeriĭ Viktorovich Tuchin Pdf

This book describes an optical clearing method based on reversible reduction of tissue scattering due to refractive index matching of scatterers and ground matter. This technique, which has been of great interest for research and application in the last decade, is a promising technique for future developments in the fields of tissue imaging, spectroscopy, phototherapy, and laser surgery.

Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues

Valery V. Tuchin
Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues Book PDF

Author : Valery V. Tuchin
Publisher : CRC Press
Page : 744 pages
File Size : 41,5 Mb
Release : 2008-12-22
Category : Science
ISBN : 1584889756

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Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues by Valery V. Tuchin Pdf

Although noninvasive, continuous monitoring of glucose concentration in blood and tissues is one of the most challenging areas in medicine, a wide range of optical techniques has recently been designed to help develop robust noninvasive methods for glucose sensing. For the first time in book form, the Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues analyzes trends in noninvasive optical glucose sensing and discusses its impact on tissue optical properties. This handbook presents methods that improve the accuracy in glucose prediction based on infrared absorption spectroscopy, recent studies on the influence of acute hyperglycemia on cerebral blood flow, and the correlation between diabetes and the thermo-optical response of human skin. It examines skin glucose monitoring by near-infrared spectroscopy (NIR), fluorescence-based glucose biosensors, and a photonic crystal contact lens sensor. The contributors also explore problems of polarimetric glucose sensing in transparent and turbid tissues as well as offer a high-resolution optical technique for noninvasive, continuous, and accurate blood glucose monitoring and glucose diffusion measurement. Written by world-renowned experts in biomedical optics and biophotonics, this book gives a complete, state-of-the-art treatise on the design and applications of noninvasive optical methods and instruments for glucose sensing.

Biomedical Photonics for Diabetes Research

Andrey Dunaev,Valery Tuchin
Biomedical Photonics for Diabetes Research Book PDF

Author : Andrey Dunaev,Valery Tuchin
Publisher : CRC Press
Page : 279 pages
File Size : 42,5 Mb
Release : 2022-10-26
Category : Science
ISBN : 9781000735611

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Biomedical Photonics for Diabetes Research by Andrey Dunaev,Valery Tuchin Pdf

In 2021, over 537 million people worldwide were diagnosed with diabetes, according to the International Diabetes Federation and so the diagnosis, care and treatment of patients with diabetes mellitus have become one of the highest healthcare priorities. Biomedical photonics methods have been found to significantly improve and assist in the diagnosis of various disorders and complications arising from diabetes. These methods have also been widely used in various studies in the field of diabetes, including in the assessment of biochemical characteristics, metabolic processes, and microcirculation that are impaired in this disease. This book provides an introduction to methods of biomedical photonics. The chapters, written by world-leading experts, cover a wide range of issues, including the theoretical basis of different biophotonics methods and practical issues concerning the conduction of experimental studies to diagnose disorders associated with diabetes. It provides a comprehensive summary of the recent advances in biomedical optics and photonics in the study of diabetes and related complications. This book will be of interest to biomedical physicists and researchers, in addition to practicing doctors and endocrinologists looking to explore new instrumental methods for monitoring the effectiveness of patient treatment. Features • The first collective book combining accumulated knowledge and experience in the field of diabetes research using biophotonics. • Contributions from leading experts in the field. • Combines the theoretical base of the described methods and approaches, as well as providing valuable practical guidance and the latest research from experimental studies.

Handbook of Photonics for Biomedical Science

Valery V. Tuchin
Handbook of Photonics for Biomedical Science Book PDF

Author : Valery V. Tuchin
Publisher : CRC Press
Page : 863 pages
File Size : 50,9 Mb
Release : 2010-05-18
Category : Medical
ISBN : 9781439806296

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Handbook of Photonics for Biomedical Science by Valery V. Tuchin Pdf

The Handbook of Photonics for Biomedical Science analyzes achievements, new trends, and perspectives of photonics in its application to biomedicine. With contributions from world-renowned experts in the field, the handbook describes advanced biophotonics methods and techniques intensively developed in recent years.Addressing the latest problems in

Biomedical Photonics Handbook

Tuan Vo-Dinh
Biomedical Photonics Handbook Book PDF

Author : Tuan Vo-Dinh
Publisher : CRC Press
Page : 842 pages
File Size : 50,9 Mb
Release : 2014-07-29
Category : Medical
ISBN : 9781420085136

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Biomedical Photonics Handbook by Tuan Vo-Dinh Pdf

Shaped by Quantum Theory, Technology, and the Genomics RevolutionThe integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in

Biomedical Photonics Handbook, Second Edition

Tuan Vo-Dinh
Biomedical Photonics Handbook Second Edition Book PDF

Author : Tuan Vo-Dinh
Publisher : CRC Press
Page : 854 pages
File Size : 55,5 Mb
Release : 2014-07-29
Category : Medical
ISBN : 9781420085129

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Biomedical Photonics Handbook, Second Edition by Tuan Vo-Dinh Pdf

Shaped by Quantum Theory, Technology, and the Genomics Revolution The integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in medical diagnostics and therapy. The second edition of the Biomedical Photonics Handbook presents recent fundamental developments as well as important applications of biomedical photonics of interest to scientists, engineers, manufacturers, teachers, students, and clinical providers. The first volume, Fundamentals, Devices, and Techniques, focuses on the fundamentals of biophotonics, optical techniques, and devices. Represents the Collective Work of over 150 Scientists, Engineers, and Clinicians Designed to display the most recent advances in instrumentation and methods, as well as clinical applications in important areas of biomedical photonics to a broad audience, this three-volume handbook provides an inclusive forum that serves as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of medical technologies. What’s New in This Edition: A wide variety of photonic biochemical sensing technologies has already been developed for clinical monitoring of physiological parameters, such as blood pressure, blood chemistry, pH, temperature, and the presence of pathological organisms or biochemical species of clinical importance. Advanced photonic detection technologies integrating the latest knowledge of genomics, proteomics, and metabolomics allow sensing of early disease states, thus revolutionizing the medicine of the future. Nanobiotechnology has opened new possibilities for detection of biomarkers of disease, imaging single molecules, and in situ diagnostics at the single-cell level. In addition to these state-of-the-art advancements, the second edition contains new topics and chapters including: • Fiber Optic Probe Design • Laser and Optical Radiation Safety • Photothermal Detection • Multidimensional Fluorescence Imaging • Surface Plasmon Resonance Imaging • Molecular Contrast Optical Coherence Tomography • Multiscale Photoacoustics • Polarized Light for Medical Diagnostics • Quantitative Diffuse Reflectance Imaging • Interferometric Light Scattering • Nonlinear Interferometric Vibrational Imaging • Multimodality Theranostics Nanoplatforms • Nanoscintillator-Based Therapy • SERS Molecular Sentinel Nanoprobes • Plasmonic Coupling Interference Nanoprobes Comprised of three books: Volume I: Fundamentals, Devices, and Techniques; Volume II: Biomedical Diagnostics; and Volume III: Therapeutics and Advanced Biophotonics, this second edition contains eight sections, and provides introductory material in each chapter. It also includes an overview of the topic, an extensive collection of spectroscopic data, and lists of references for further reading.

Biomedical Photonics Handbook, 3 Volume Set

Tuan Vo-Dinh
Biomedical Photonics Handbook 3 Volume Set Book PDF

Author : Tuan Vo-Dinh
Publisher : CRC Press
Page : 2524 pages
File Size : 52,9 Mb
Release : 2014-07-29
Category : Medical
ISBN : 9781439863190

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Biomedical Photonics Handbook, 3 Volume Set by Tuan Vo-Dinh Pdf

Shaped by Quantum Theory, Technology, and the Genomics RevolutionThe integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in

Handbook of Neurophotonics

Francesco S. Pavone,Shy Shoham
Handbook of Neurophotonics Book PDF

Author : Francesco S. Pavone,Shy Shoham
Publisher : CRC Press
Page : 579 pages
File Size : 50,9 Mb
Release : 2020-05-10
Category : Medical
ISBN : 9781498718769

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Handbook of Neurophotonics by Francesco S. Pavone,Shy Shoham Pdf

The Handbook of Neurophotonics provides a dedicated overview of neurophotonics, covering the use of advanced optical technologies to record, stimulate, and control the activity of the brain, yielding new insight and advantages over conventional tools due to the adaptability and non-invasive nature of light. Including 32 colour figures, this book addresses functional studies of neurovascular signaling, metabolism, electrical excitation, and hemodynamics, as well as clinical applications for imaging and manipulating brain structure and function. The unifying theme throughout is not only to highlight the technology, but to show how these novel methods are becoming critical to breakthroughs that will lead to advances in our ability to manage and treat human diseases of the brain. Key Features: Provides the first dedicated book on state-of-the-art optical techniques for sensing and imaging across at the cellular, molecular, network, and whole brain levels. Highlights how the methods are used for measurement, control, and tracking of molecular events in live neuronal cells, both in basic research and clinical practice. Covers the entire spectrum of approaches, from optogenetics to functional methods, photostimulation, optical dissection, multiscale imaging, microscopy, and structural imaging. Includes chapters that show use of voltage-sensitive dye imaging, hemodynamic imaging, multiphoton imaging, temporal multiplexing, multiplane microscopy, optoacoustic imaging, near-infrared spectroscopy, and miniature neuroimaging devices to track cortical brain activity.

Handbook of Optical Biomedical Diagnostics

Valeriĭ Viktorovich Tuchin
Handbook of Optical Biomedical Diagnostics Book PDF

Author : Valeriĭ Viktorovich Tuchin
Publisher : Unknown
Page : 688 pages
File Size : 42,8 Mb
Release : 2016
Category : Electronic books
ISBN : 1628419121

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Handbook of Optical Biomedical Diagnostics by Valeriĭ Viktorovich Tuchin Pdf

This text begins by describing the basic principles and diagnostic applications of optical techniques based on detecting and processing the scattering, fluorescence, FT IR, and Raman spectroscopic signals from various tissues, with an emphasis on blood, epithelial tissues, and human skin. The second half of the volume discusses specific imaging technologies, such as Doppler, laser speckle, optical coherence tomography (OCT), and fluorescence and photoacoustic imaging.

Handbook of Biomedical Optics

David A. Boas,Constantinos Pitris,Nimmi Ramanujam
Handbook of Biomedical Optics Book PDF

Author : David A. Boas,Constantinos Pitris,Nimmi Ramanujam
Publisher : CRC Press
Page : 816 pages
File Size : 47,8 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781420090376

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Handbook of Biomedical Optics by David A. Boas,Constantinos Pitris,Nimmi Ramanujam Pdf

Biomedical optics holds tremendous promise to deliver effective, safe, non- or minimally invasive diagnostics and targeted, customizable therapeutics. Handbook of Biomedical Optics provides an in-depth treatment of the field, including coverage of applications for biomedical research, diagnosis, and therapy. It introduces the theory and fundamental

The Optical Clearing Method

Luís Manuel Couto Oliveira,Valery Victorovich Tuchin
The Optical Clearing Method Book PDF

Author : Luís Manuel Couto Oliveira,Valery Victorovich Tuchin
Publisher : Springer Nature
Page : 183 pages
File Size : 53,6 Mb
Release : 2019-11-27
Category : Science
ISBN : 9783030330552

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The Optical Clearing Method by Luís Manuel Couto Oliveira,Valery Victorovich Tuchin Pdf

This book describes the Optical Immersion Clearing method and its application to acquire information with importance for clinical practice and various fields of biomedical engineering. The method has proved to be a reliable means of increasing tissue transparency, allowing the investigator or surgeon to reach deeper tissue layers for improved imaging and laser surgery. This result is obtained by partial replacement of tissue water with an active optical clearing agent (OCA) that has a higher refractive index and is a better match for the refractive index of other tissue components. Natural tissue scattering is thereby reduced. An exponential increase in research using this method has occurred in recent years, and new applications have emerged, both in clinical practice and in some areas of biomedical engineering. Recent research has revealed that treating ex vivo tissues with solutions containing active OCAs in different concentrations produces experimental data to characterize drug delivery or to discriminate between normal and pathological tissues. The obtained drug diffusion properties are of interest for the pharmaceutical and organ preservation industry. Similar data can be estimated with particular interest for food preservation. The free water content evaluation is also of great interest since it facilitates the characterization of tissues to discriminate pathologies. An interesting new application that is presented in the book regards the creation of two optical windows in the ultraviolet spectral range through the application of the immersion method. These induced transparency windows open the possibility to diagnose and treat pathologies with ultraviolet light. This book presents photographs from the tissues we have studied and figures that represent the experimental setups used. Graphs and tables are also included to show the numerical results obtained in the sequential calculations performed.

Optical Coherence Tomography in Dentistry

Anderson S. L. Gomes,Denise M. Zezell,Cláudia C. B. O. Mota,John M. Girkin
Optical Coherence Tomography in Dentistry Book PDF

Author : Anderson S. L. Gomes,Denise M. Zezell,Cláudia C. B. O. Mota,John M. Girkin
Publisher : CRC Press
Page : 275 pages
File Size : 47,8 Mb
Release : 2023-08-08
Category : Computers
ISBN : 9781351104548

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Optical Coherence Tomography in Dentistry by Anderson S. L. Gomes,Denise M. Zezell,Cláudia C. B. O. Mota,John M. Girkin Pdf

Optical Coherence Tomography (OCT), a method to "see inside of things" without destroying them, has been applied to subjects ranging from materials science to medicine. This book focuses on the biomedical application of OCT in dentistry, covering topics from dental materials to clinical practice. Since the introduction of the OCT method in ophthalmology in 1991, and then dentistry in 1998, developments in OCT methods, particularly in biomedical areas, have led to its dissemination worldwide. The chapters of this book cover the basics and recent global advances of OCT in dentistry, including an overview of the method and its use in cariology, restorative dentistry, dental materials, endodontics, pediatric dentistry, orthodontics, prosthodontics, soft oral tissues and nanodentistry. This book will be of interest to both newcomers in the field as well as those already working in OCT, either in research and/or the clinic. It will be of great use in courses on optical imaging applied to biomedical areas, particularly where it can provide real-life examples of the application of OCT.

Fluorescence Spectroscopy and Microscopy in Biology

Radek Šachl,Mariana Amaro
Fluorescence Spectroscopy and Microscopy in Biology Book PDF

Author : Radek Šachl,Mariana Amaro
Publisher : Springer Nature
Page : 532 pages
File Size : 54,7 Mb
Release : 2023-04-27
Category : Science
ISBN : 9783031303623

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Fluorescence Spectroscopy and Microscopy in Biology by Radek Šachl,Mariana Amaro Pdf

This book provides the reader with an updated comprehensive view of the rapidly developing and fascinating field of fluorescence spectroscopy and microscopy. In recent years, fluorescence spectroscopy and microscopy have experienced rapid technological development, which has enabled the detection and monitoring of single molecules with high spatial and temporal resolution. Thanks to these developments, fluorescence has become an even more popular method in physical, biological and related fields. This book guides the reader through both basic and advanced fluorescence spectroscopy and microscopy approaches with a focus on their applications in membrane and protein biophysics. Each of the four parts: A - Fluorescence Spectroscopy, B - Fluorescence Microscopy, C - Applications of Fluorescence Spectroscopy and Microscopy to biological membranes and D - Applications of Fluorescence Spectroscopy to protein studies are written by experts within the field. The book is intended for both complete beginners who want to quickly orient themselves in the large number of existing fluorescent methods, as well as for advanced readers who are interested in particular methods and their proper use.