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Author : David Michael Rosen
Publisher : Unknown
Page : 424 pages
File Size : 43,7 Mb
Release : 1982
Category : Collagen
ISBN : UCR:31210004311625
Author : David Feldman,J. Wesley Pike,Francis H. Glorieux
Publisher : Elsevier
Page : 1952 pages
File Size : 55,9 Mb
Release : 2005-01-25
Category : Medical
ISBN : 9780080543642
Vitamin D, a steroid hormone, has mainly been known for its effects on bone and osteoporosis. The current therapeutic practices expand into such markets as cancer research, pediatrics, nephrology, dermatology, immunology, and genetics. This second edition includes over 100 chapters covering everything from chemistry and metabolism to mechanisms of action, diagnosis and management, new analogs, and emerging therapies. This complete reference works is a must have resource for anyone working in endocrinology, osteology, bone biology, or cancer research. *Most comprehensive, up-to-date two-volume set on Vitamin D *New chapters on squamous cell cancer, brain cancer, thyroid cancer and many more *Further sections on emerging uses for treatments of auto-immune diseases and diabetes *Over 600 illustrations and figures available on CD
Author : John P. Bilezikian,Robert Marcus,Michael A. Levine
Publisher : Elsevier
Page : 881 pages
File Size : 44,5 Mb
Release : 2001-07-21
Category : Science
ISBN : 0080525776
Written by world experts, this books follows upon the monumental success of the first edition of The Parathyroids, which was universally acclaimed as the best text on the subject. An authoritative reference that spans the basic science of parathyroid hormone treatment to major clinical disorders in a superb, single compendium, The Parathyroids offers an objective and authoritative view on controversial clinical issues in this rapidly changing field. Every medical school library and virtually every major hospital library will need this book as a reference for students and clinicians. Key Features * Offers objective and authoritative reviews on controversial clinical issues * Written by world experts on parathyroid hormone and its disorders * Superb, state-of-the-art compendium in one convenient volume * Bridges basic science of parathyroid hormone to major clinical disorders * Practical information on clinical management of parathyroid hormone disorders
Author : Anonim
Publisher : Unknown
Page : 1840 pages
File Size : 46,7 Mb
Release : 2000
Category : Medicine
ISBN : OSU:32436010864682
Author : David O. Carpenter,Sinerik Ayrapetyan
Publisher : Academic Press
Page : 357 pages
File Size : 49,7 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780080886886
Recent concerns over the possible hazards of electrical and magnetic fields in the home and workplace are comprehensively addressed within this book. The chapters contain detailed research on the biological effects of electric and magnetic fields, and evidence for and against any interaction of electromagnetic fields (EMFs) and the biological systems. The relative risk of exposure to EMFs Putative behavioral and neural effects of EMFs EMF effects on cells
Author : M.F. Crass, III,Louis V. Avioli
Publisher : CRC Press
Page : 344 pages
File Size : 41,6 Mb
Release : 1994-12-27
Category : Medical
ISBN : 0849386616
This is the first book to exclusively address the actions of calcium-regulating hormones and peptides in the cardiovascular system. With 111 illustrations and 13 tables, this comprehensive volume includes: An extensive and critical review of present knowledge of the structure, synthesis, secretion, metabolism, receptors, signal transduction, and actions on classical target cells of each of the calcium-regulating hormones and peptides Discussions on parathyroid hormone and calcitonin, parathyroid hormone-related protein, parathyroid hypertensive factor, 1,25 dihydroxyvitamin D3, calcitonin gene-related peptide, and certain steroid hormones in terms of vascular biology and cardiac function The integrated physiology of calcium-regulating hormones in terms of blood pressure regulation in normotensive and hypertensive settings State-of-the-art electrophysiological techniques used by leading cardiovascular biologists to assess calciotropic hormone effects on calcium channel currents in both vascular smooth muscle and cardiac myocytes Studies on the regulation of hormone and receptor gene expression in the context of possible regulation of local and systemic blood flow and cardiac function by calcium-regulating hormones and peptides
Author : J.-Y. Reginster,J.-P. Pelletier,J. Martel-Pelletier,Y. Henrotin
Publisher : Springer Science & Business Media
Page : 509 pages
File Size : 40,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642600265
Musculoskeletal diseases are rapidly becoming a major health concern. The incidence of osteoarthritis, the most common arthritic disorder, is increasing steadily due to the graying of the world population. This disease is responsible of human life, a time in for significant morbidity, particularly in the second half which the quality of life is of primary importance. The aim of this publication is to bring to physicians and scientists a comprehensive overview of the field, from molecules to men. The direct costs related to osteoarthritis have been increasing steadily over the years and will soon be comparable to those of other major illnesses, such as cardiovascular diseases. This, of course, does not take into account all of the other costs related to the disease which often cannot be simply calculated in dollars and cents. There has been a great deal of renewed interest in osteoarthritis in the last few decades. This has been brought on by the need to improve our knowledge of all aspects of the disease, especially with regard to its etiopathogenesis and treatment. The most recent findings and developments on the structural, bio chemical, biomechanical and molecular changes observed in clinical and ex perimental osteoarthritis are presented in this book.
Author : John P. Bilezikian,Lawrence G. Raisz,Gideon A. Rodan
Publisher : Academic Press
Page : 1702 pages
File Size : 55,7 Mb
Release : 2002-01-19
Category : Medical
ISBN : 9780080539607
Principles of Bone Biology is the essential resource for anyone involved in the study of bones. It is the most comprehensive, complete, up-to-date source of information on all aspects of bones and bone biology in one convenient source. Written and published in less than one year, it will become an indispensable resource for any scientific or medical library. This, second edition, details countless advances over the past five years, both by updating old chapters and providing additional material. It takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics. The most current and timely source of information about the biology and pathology of boneProvides succinct coverage of the subjectContributors include over 200 of the most respected researchers in the fieldExtensive table of contents and index for easy referenceEasy-to-read and highly informative to both the newcomer and the initiated to the field Spans the spectrum from molecular biology to in vivo pharmacologyComplete bibliography with each entry fully referenced for additional background reading First edition was selected by Doody Publishing as one of the 250 Best Health Science books published in 1996
Author : United States Public Health Service,Surgeon General of the United States
Publisher : Unknown
Page : 0 pages
File Size : 42,5 Mb
Release : 2004-12
Category : Health & Fitness
ISBN : 1410219275
This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.
Author : C. Nicolini
Publisher : Springer Science & Business Media
Page : 216 pages
File Size : 52,8 Mb
Release : 2013-11-21
Category : Medical
ISBN : 9781489925633
During May 21-June 1 1990, the eleventh course of the International School of Pure and Applied Biostructure, a NATO Advanced Study Institute, was held at the Ettore Majorana Center for Scientific Culture in Erice, Italy, co-sponsored by the Italian Ministry of Universities and of Scientific and Technological Research, the North Atlantic Treaty Organization, the Italian National Research Council, the Sicilian Regional Government and Technobiochip. The subject of the course was "Molecular Basis of Human Cancer" with participants selected worldwide from 15 different countries. The purpose of the course was to address, in a tutorial and structural fashion, the molecular basis of human cancer, including the mechanism of signal transduction in mammalian cells, the genetic mechanism of malignant transformation in man, growth factors, hormone receptors, cell membrane and cytoskeleton, and DNA high order structure. The course had this as its major objective and the resulting book reflects it. The participants were exposed to a critical evaluation of current knowledge about cancer and to some of the key problems that remain as stumbling blocks to our eventual understanding of this important biological and medical problem. Through the media of formal and informal lectures, workshops, symposia and informal discussions, a select group of interested young and senior scientists were acquainted with many of the aspects of human cancer.
Author : Gregory R. Mundy,T.John Martin
Publisher : Springer Science & Business Media
Page : 774 pages
File Size : 50,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642779916
The authors, all accomplished and world-renowned experts in their topic areas, have provided controversial and up-to-date accounts of the current status of research in calcium and bone metabolism by reviewing major areas of basic science which have an impact on the understanding of bone diseases and related disorders.
Author : Maxine Gowen
Publisher : CRC Press
Page : 432 pages
File Size : 47,6 Mb
Release : 1991-12-18
Category : Medical
ISBN : 0849362687
Cytokines and Bone Metabolism presents a comprehensive review of the research done to date on the role of cytokines in bone metabolism. All of the major groups of cytokines and growth factors are covered, and more than 2,000 references are included. In each chapter, the biochemistry and wider cellular actions of individual factors are reviewed before data detailing the in vitro and in vivo actions in bone are presented. Extensive reviews of the cell biology of bone, the potential role of cytokines in bone diseases, and the theoretical and practical possibilities for pharmacological intervention based on cytokines as targets are also provided. Cytokines and Bone Metabolism is an indispensable reference for researchers and students in a wide range of medical fields.
Author : Melvin J. Glimcher,Jane B. Lian
Publisher : CRC Press
Page : 1096 pages
File Size : 52,7 Mb
Release : 1989
Category : Science
ISBN : 067722320X
The proceedings of the Third International Conference (on title) held in Chatham, Mass., October, 1988. Presents coverage of many areas of the skeletal system, including new experimental techniques, research areas, ideas, and hypotheses. Discusses at length the chemical nature and structure of organic matrix components and their influence with respect to regulation of cell function. Annotation copyrighted by Book News, Inc., Portland, OR
Author : Robert Marcus,David Feldman,Dorothy Nelson,Clifford Rosen
Publisher : Academic Press
Page : 551 pages
File Size : 53,8 Mb
Release : 2009-09-24
Category : Medical
ISBN : 9780123751089
Fundamentals of Osteoporosis offers a concise yet comprehensive source of all the latest basic research related to osteoporosis in one reference work. Experts from all areas of osteoporosis research expose readers to genomic and proteomic analysis, and histopathology and imaging, as well cellular and molecular mechanisms relevant to assay development and drug discovery. Presents a concise yet comprehensive source of all the latest basic research related to osteoporosis in one reference work Experts from all areas of osteoporosis research expose readers to genomic and proteomic analysis, histopathology and imaging, as well cellular and molecular mechanisms relevant to assay development and drug discovery Clear, concise presentations by bone biologists of the cellular and molecular mechanisms underlying osteoporosis
Author : Carolyn D. Berdanier
Publisher : CRC Press
Page : 591 pages
File Size : 53,9 Mb
Release : 2018-01-18
Category : Medical
ISBN : 9781351083560
Nutrition and Gene Expression is devoted to exploring the tissue-specific and developmental aspects of the interaction between nutrients and the genome. The book discusses chemical sensitivity in relation to the ability of cells to detect nutrients; reviews the means by which lower organisms respond to nutrients; and provides examples on how each of the classes of nutrients affects genetic transcription, mRNA translation or stability. The receptor-mediated actions of vitamin D and retinoic acid on gene expression are discussed, including the case of bone formation and dissolution. Other important topics covered in the volume include newly discovered effects of fatty acids on regulating gene expression, the effects of diet on mRNA editing, the interplay between dietary carbohydrates and proteins in regulating metabolism of liver cells, the effects of metal ions on protein synthesis, and much more. Nutrition and Gene Expression is an important reference for nutritionists, physiologists, biochemists, clinical nutritionists, pharmaceutical researchers, geneticists, and food scientists.