Ige Receptor Fceri Function In Mast Cells And Basophils

Author : Majed M. Hamawy
Publisher : Springer Science & Business Media
Page : 298 pages
File Size : 53,6 Mb
Release : 2013-06-29
Category : Medical
ISBN : 9783662220221

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IgE Receptor (FcεRI) Function in Mast Cells and Basophils by Majed M. Hamawy Pdf

The high affinity IgE receptor (FceRI) plays a central role in allergic diseases including asthma, allergic rhinitis, atopic dermatitis, food and drug allergy. Manipulating the function of this receptor is important for controlling the onset of allergic diseases. Written by leading scientists in the field, this book is the first comprehensive monograph to cover various aspects of FceRI structure, signal transduction and function. Thus, the book is valuable for researchers/students working on FceRI and on other receptors. In addition, clinicians who are concerned with broadening their knowledge of the FceRI role in allergic diseases will find this book useful.

Author : Majed M. Hamawy
Publisher : Unknown
Page : 292 pages
File Size : 44,8 Mb
Release : 1997-01-01
Category : Fc receptors
ISBN : 1570593809

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IGE Receptor (FceRI) Function in Mast Cells and Basophils by Majed M. Hamawy Pdf

Author : Ehud Razin,Juan Rivera
Publisher : Springer Science & Business Media
Page : 438 pages
File Size : 46,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461221548

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Signal Transduction in Mast Cells and Basophils by Ehud Razin,Juan Rivera Pdf

Focussing on the molecular mechanisms that govern mast cell and basophil cell biology and function, this book also provides a comprehensive summary of the field of signal transduction, giving insights into areas that have therapeutic potential. It gives detailed insights into mast cell and basophil growth and development, their activation by allergens, including details of receptor activation and downstream events, and the regulators of morphology and degranulation. The metabolic pathways involved in prostaglandin and leukotriene production are discussed as is the role of transcription factors in mast cell growth and cytokine production. Written by leaders in the field, this volume will provide readers with an up-to-date account of a topic whose rapid progress makes conventional information gathering difficult.

Author : Derek J. Chadwick,David Evered,Julie Whelan
Publisher : John Wiley & Sons
Page : 292 pages
File Size : 47,9 Mb
Release : 2008-04-30
Category : Medical
ISBN : 9780470513873

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IgE, Mast Cells and the Allergic Response by Derek J. Chadwick,David Evered,Julie Whelan Pdf

Reviews recent basic research into IgE, mast cells, and the allergic response and the relevance of this work to human pathophysiology, and discusses new methods of treatment. This symposium is unique in the IgE field for its breadth of coverage and interdisciplinary nature, and it shows the benefits from the current rapid expansion of knowledge in cell biology, immunology, and molecular genetics, as well as the potential clinical significance of this research to clinical immunologists and allergologists.

Author : Derek J. Chadwick,Jamie A. Goode
Publisher : John Wiley & Sons
Page : 274 pages
File Size : 55,7 Mb
Release : 2006-01-04
Category : Medical
ISBN : 9780470030516

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Mast Cells and Basophils by Derek J. Chadwick,Jamie A. Goode Pdf

The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and basophils; discussion of new technologies used to study these cells, and integration of the basic scientific findings in the context of therapeutic possibilities for the treatment of diseases such as allergic inflammation and autoimmune disease which are mediated, in part, by these granulocytes.

Author : Gianni Marone,Lawrence M. Lichtenstein,Federica J. Galli
Publisher : Academic Press
Page : 738 pages
File Size : 45,5 Mb
Release : 2000-05-25
Category : Medical
ISBN : 9780080535852

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Mast Cells and Basophils by Gianni Marone,Lawrence M. Lichtenstein,Federica J. Galli Pdf

Mast Cells and Basophils will be essential reading for immunologists, biochemists and medical researchers. Detailed chapters cover all aspects of mast cell and basophil research, from cell development, proteases, histamine, cysteinyl leukotrienes, physiology and pathology to the role of these cells in health and disease. Chapters also discuss the clinical implications of histamine receptor antagonists.

Author : Majed M. Hamawy
Publisher : Springer Science & Business Media
Page : 292 pages
File Size : 48,7 Mb
Release : 1997-01-01
Category : Fc receptors
ISBN : 3540615393

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IGE Receptor (FceRI) Function in Mast Cells and Basophils by Majed M. Hamawy Pdf

The high affinity IgE receptor (FceRI) plays a central role in allergic diseases including asthma, allergic rhinitis, atopic dermatitis, food and drug allergy. Manipulating the function of this receptor is important for controlling the onset of allergic diseases. Written by leading scientists in the field, this book is the first comprehensive monograph to cover various aspects of FceRI structure, signal transduction and function. Thus, the book is valuable for researchers/students working on FceRI and on other receptors. In addition, clinicians who are concerned with broadening their knowledge of the FceRI role in allergic diseases will find this book useful.

Author : John C. Foreman
Publisher : Academic Press
Page : 264 pages
File Size : 44,8 Mb
Release : 1993-11-29
Category : Medical
ISBN : UOM:39015032906821

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Immunopharmacology of Mast Cells and Basophils by John C. Foreman Pdf

There has been a steady and continued research effort directed to understanding both the function and the role of mast cells and basophils ever since these cells were first described at the end of the nineteenth century. One of the most significant advances has perhaps been the appreciation of the fact that mast cells do not represent a single homogenous population of cells: they display heterogeneity at the morphological, biochemical and functional levels. The one characteristic that unites all types of mast cells and basophils appears to be the possession of the high affinity membrane receptor for immunoglobulin E, through which the cells may be stimulated. This volume begins with a review of the origin and development of mast cells and basophils. It continues by reviewing our knowledge of the stimuli to mast cells and basophils and the biochemical mechanisms which link the signal generated by stimulus to the response machinery of the cell. Further chapters deal with the drug control of mast cell and basophil responses, the heterogeneity of the cells' functions and the mediators' release by the cells, along with the morphological aspects of the cells' function. This book is completed by a selection of examples which examine the role of the mast cells or basophils in lung, skin and gastrointestinal tract. However, the role of the mast cell with regard to normal physiology, remains an open question. This book aims to provide an up-to-date account of mast cell and basophil biology, together with an insight into the functional relevance of these cells in some tissue types.

Author : Bernhard F. Gibbs,Franco H. Falcone
Publisher : Springer Nature
Page : 379 pages
File Size : 41,9 Mb
Release : 2020-08-06
Category : Medical
ISBN : 9781071606964

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Basophils and Mast Cells by Bernhard F. Gibbs,Franco H. Falcone Pdf

This second edition provides updated and new chapters to build on and extend the strengths of the first edition. Chapters guide readers through basic biology of basophils, obtaining the cells by purification, culture of stem cells progenitors, peripheral CD34+ stem cell-derived mast cells, basophils from CD34+ progenitors, diagnostic applications, gene expression patterns in basophils, roles of basophils in different asthma phenotypes, knockout, and disease models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Basophils and Mast Cells: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.

Author : Stephen T. Holgate
Publisher : Springer Science & Business Media
Page : 293 pages
File Size : 47,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400912878

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Mast Cells, Mediators and Disease by Stephen T. Holgate Pdf

In 1879 Paul Ehrlich first described the mast cell as a tissue fixed cell contain ing many granules which, when stained with basic dyes, such as toluidine blue, changed the colour spectrum of the dye in a process called meta chromasia. Since this early description, pathologists, physicians and pharmacologists have been fascinated by this cell on account of its central involvement in human allergic diseases. Approximately four decades after Ehrlich's first description of the mast cell, Prausnitz and Kiistner reported their pioneer experiment, demonstrating that the immediate skin wheal response to allergen could be passively transferred with serum. They named the antigen-specific serum factor reagin. A further four and one half decades had to pass before the connection between the mast cell and reagin could be made with the identification of reagin as an immunoglobulin E by Johansson and Ishizaka and its unique property to bind with high affinity to specific receptors on mast cells and basophils. Meanwhile in the 1920s Coca published a series of papers in which he described the clinical features of acute allergic responses and first used the term atopy. This, together with the fundamental pharmacological studies of Sir Henry Dale in identifying histamine as one mediator of the acute ana phylactic reaction, provided the second approach which eventually linked the mast cell to allergic tissue reactions. Indeed, it was Best, working in Dale's group who first showed that histamine was a chemical stored in mast cells.

Author : Gianni Marone
Publisher : S. Karger AG (Switzerland)
Page : 290 pages
File Size : 48,7 Mb
Release : 1995
Category : Basophils
ISBN : PURD:32754065281549

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Human Basophils and Mast Cells by Gianni Marone Pdf

"Expert contributions cover disorders, such as mastocytosis and respiratory and cutaneous allergy, which are known to be associated with these cells. The less well-known involvement of the latter in atherosclerosis and gastrointestinal, cardiac, rheumatic and neoplastic diseases is emerging as an area of considerable interest as several informative chapters show. Written by clinical investigators specialising in diseases related to mast cells and basophils, this volume will be stimulating reading for those working in allergy, immunology, biochemistry, and respiration."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved

Author : Stephen J. Galli,Karl Frank Austen
Publisher : Raven Press (ID)
Page : 376 pages
File Size : 46,5 Mb
Release : 1989
Category : Medical
ISBN : UOM:39015014484169

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Mast Cell and Basophil Differentiation and Function in Health and Disease by Stephen J. Galli,Karl Frank Austen Pdf

Author : Satoshi Tanaka,Frans J. Van Overveld
Publisher : Frontiers Media SA
Page : 353 pages
File Size : 52,6 Mb
Release : 2023-04-20
Category : Medical
ISBN : 9782832521212

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Novel Insights into Inflammatory Roles of Mast Cells and Basophils by Satoshi Tanaka,Frans J. Van Overveld Pdf

Author : Gianni Marone
Publisher : Unknown
Page : 264 pages
File Size : 55,9 Mb
Release : 1995
Category : Basophils
ISBN : PURD:32754065290516

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Human Basophils and Mast Cells by Gianni Marone Pdf

Author : Hirohisa Saito,Yoshimichi Okayama
Publisher : Karger Medical and Scientific Publishers
Page : 233 pages
File Size : 50,7 Mb
Release : 2005-01-01
Category : Medical
ISBN : 9783805579483

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Mast Cells in Allergic Diseases by Hirohisa Saito,Yoshimichi Okayama Pdf

In this book, the editors have focused on the roles of mast cells in allergic diseases and discuss the future direction of discovering drugs. Another implication of this book is to understand mast cells at the system level. System biology is a research category to understand biology at the system level by examining the structure and dynamics of cellular and organismal functions, rather than the characteristics of isolated parts of a cell or organism.