In Vitro Interactions Of Γ Tubulin And Microtubules

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Microtubules, in vitro

Author : John J. Correia,Leslie Wilson
Publisher : Academic Press
Page : 472 pages
File Size : 49,5 Mb
Release : 2013-08-20
Category : Science
ISBN : 9780124078888

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Microtubules, in vitro by John J. Correia,Leslie Wilson Pdf

There continues to be intense interest in the microtubule cytoskeleton; the assembly, structure and regulation of microtubules; and the numerous motors and accessory proteins that control cell cycle, dynamics, organization and transport. The field continues to grow and explore new aspects of these issues driven immensely by developments in optical imaging and tracking techniques. This Second Edition brings together current research and protocols in the field of microtubules in vitro and will serve as a valuable tool for cell biologists, biophysicists and pharmacologists who study the microtubule cytoskeleton, as well as for researchers in the biomedical and biotechnology communities with interest in developing drugs that target microtubules, MAPS and motors. Chapters reflect experimental procedures and new developments in the field of microtubule in vitro research Combines classical approaches and modern technologies Presents easy-to-use protocols and thorough background information, compiled by leaders in the field

Cytoskeleton

Author : Jose C. Jimenez-Lopez
Publisher : BoD – Books on Demand
Page : 344 pages
File Size : 44,6 Mb
Release : 2017-05-17
Category : Science
ISBN : 9789535131694

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Cytoskeleton by Jose C. Jimenez-Lopez Pdf

The cytoskeleton is a highly dynamic intracellular platform constituted by a three-dimensional network of proteins responsible for key cellular roles as structure and shape, cell growth and development, and offering to the cell with "motility" that being the ability of the entire cell to move and for material to be moved within the cell in a regulated fashion (vesicle trafficking). The present edition of Cytoskeleton provides new insights into the structure-functional features, dynamics, and cytoskeleton's relationship to diseases. The authors' contribution in this book will be of substantial importance to a wide audience such as clinicians, researches, educators, and students interested in getting updated knowledge about molecular basis of cytoskeleton, such as regulation of cell vital processes by actin-binding proteins as cell morphogenesis, motility, their implications in cell signaling, as well as strategies for clinical trial and alternative therapies based in multitargeting molecules to tackle diseases, that is, cancer.

Microtubule Dynamics

Author : Anne Straube
Publisher : Humana Press
Page : 319 pages
File Size : 53,8 Mb
Release : 2017-04-30
Category : Science
ISBN : 1493961853

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Microtubule Dynamics by Anne Straube Pdf

Microtubules are at the heart of cellular self-organization, and their dynamic nature allows them to explore the intracellular space and mediate the transport of cargoes from the nucleus to the outer edges of the cell and back. In Microtubule Dynamics: Methods and Protocols, experts in the field provide an up-to-date collection of methods and approaches that are used to investigate microtubule dynamics in vitro and in cells. Beginning with the question of how to analyze microtubule dynamics, the volume continues with detailed descriptions of how to isolate tubulin from different sources and with different posttranslational modifications, methods used to study microtubule dynamics and microtubule interactions in vitro, techniques to investigate the ultrastructure of microtubules and associated proteins, assays to study microtubule nucleation, turnover, and force production in cells, as well as approaches to isolate novel microtubule-associated proteins and their interacting proteins. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Definitive and practical, Microtubule Dynamics: Methods and Protocols provides the key protocols needed by novices and experts on how to perform a broad range of well-established and newly-emerging techniques in this vital field.

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 51,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Methods for Analysis of Golgi Complex Function

Author : Anonim
Publisher : Elsevier
Page : 499 pages
File Size : 46,9 Mb
Release : 2013-11-26
Category : Science
ISBN : 9780124171831

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Methods for Analysis of Golgi Complex Function by Anonim Pdf

This new volume of Methods in Cell Biology looks at methods for analyzing of golgi complex function. Chapters cover such topics as in vitro reconstitution systems, fluorescence-based analysis of trafficking in mammalian cells and high content screening. With cutting-edge material, this comprehensive collection is intended to guide researchers for years to come. Covers sections on model systems and functional studies, imaging-based approaches and emerging studies Chapters are written by experts in the field Cutting-edge material

The isotypes of α, β and γ tubulin: From evolutionary origins to roles in metazoan development and ligand binding differences

Author : Jeffrey Moore,Richard Luduena,Jack Adam Tuszynski
Publisher : Frontiers Media SA
Page : 173 pages
File Size : 53,9 Mb
Release : 2023-04-25
Category : Science
ISBN : 9782832521458

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The isotypes of α, β and γ tubulin: From evolutionary origins to roles in metazoan development and ligand binding differences by Jeffrey Moore,Richard Luduena,Jack Adam Tuszynski Pdf

Molecular Anatomy of Cellular Systems

Author : I. Endo,I. Yamaguchi,T. Kudo,H. Osada,T. Shibata
Publisher : Elsevier
Page : 241 pages
File Size : 55,6 Mb
Release : 2002-08-20
Category : Science
ISBN : 9780080536743

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Molecular Anatomy of Cellular Systems by I. Endo,I. Yamaguchi,T. Kudo,H. Osada,T. Shibata Pdf

In this book, the progress during the last ten years is reviewed and future plans outlined to realize and establish the concept of design in the biological sciences. Design is a leading concept as well as the principal motivation for the creation of artificial systems. A successful design generally requires that the structures and functions of the elements that constitute the system as well as the principles that determine how the elements cooperate together to create function be fully understood. These requirements have not been satisfied within the fields of biotechnology and medicine. Compared to the recent emergence of artificial systems, living organisms acquired their present day structures and functions through evolution over three to four billion years. Despite the fact that the design of living organisms is recorded in the DNA sequence, our understanding of the structures and functions of the elements that constitute living organisms is very limited. To fulfill the requirements, the following approaches were initiated under a ten-year project entitled "Biodesign Research". Firstly, we tried to isolate and characterize the functional elements that constitute the organelles of various organisms. Secondly, we tried to reconstitute systems that reproduce biological functions in vitro from individual elements in order to understand how the elements cooperate together to yield a function. Thirdly, we attempted to resolve biological structures at various resolutions ranging from the atomic to the cellular level to further our knowledge about the fundamental principles that various functions at the molecular level and to design artificial systems.

Centrosomes and Spindle Pole Bodies

Author : Robert E. Palazzo,Trisha N. Davis
Publisher : Gulf Professional Publishing
Page : 412 pages
File Size : 43,6 Mb
Release : 2001-08-27
Category : Medical
ISBN : 0125439857

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Centrosomes and Spindle Pole Bodies by Robert E. Palazzo,Trisha N. Davis Pdf

Containing a comprehensive collection of convenient and quantitative methods for studying centrosomes, spindle pole bodies and related organelles, this text is a valuable resource for researchers and others interested in studying the role of these organelles in cell replication. Chapters outlining the role of these organelles in other cell functions are also included, and a wide variety of experimental systems for analyzing these organelles are presented. Detailed protocols for experiments are contained in each chapter for researchers to perform in their own labs. This volume outlines key methodologies used to analyze centrosomes and spindle pole bodies, their replication, and reproduction in the clear, well-illustrated style of the Methods in Cell Biology series.

The Role of Microtubules in Cell Biology, Neurobiology, and Oncology

Author : Antonio Tito Fojo
Publisher : Springer Science & Business Media
Page : 629 pages
File Size : 48,5 Mb
Release : 2009-01-14
Category : Medical
ISBN : 9781597453363

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The Role of Microtubules in Cell Biology, Neurobiology, and Oncology by Antonio Tito Fojo Pdf

This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and investigates the potential of microtubules in cancer therapy.

The Golgi Apparatus

Author : Eric Berger,J. Roth
Publisher : Birkhäuser
Page : 306 pages
File Size : 54,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783034888769

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The Golgi Apparatus by Eric Berger,J. Roth Pdf

In 1898 Camillo Golgi reported his newly observed intracellular structure, the apparato reticolare interno, now universally known as the Golgi Apparatus. The method he used was an ingenious histological technique (La reazione nera) which brought him fame for the discovery of neuronal networks and culminated in the award of the Nobel Prize for Physiology and Medicine in 1906. This technique, however, was not easily reproducible and led to a long-lasting controversy about the reality of the Golgi apparatus. Its identification as a ubiquitous organelle by electron microscopy turned out to be the breakthrough and incited an enormous wave of interest in this organelle at the end of the sixties. In recent years immunochemical techniques and molecular cloning approaches opened up new avenues and led to an ongoing resurgence of interest. The role of the Golgi apparatus in modifying, broadening and refining the structural information conferred by transcription/translation is now generally accepted but still incompletely understood. During the coming years, this topic certainly will remain center stage in the field of cell biology. The centennial of the discovery of this fascinating organelle prompted us to edit a new comprehensive book on the Golgi apparatus whose complexity necessitated the contributions of leading specialists in this field. This book is aimed at a broad readership of glycobiologists as well as cell and molecular biologists and may also be interesting for advanced students of biology and life sciences.

Cumulated Index Medicus

Author : Anonim
Publisher : Unknown
Page : 1764 pages
File Size : 42,7 Mb
Release : 2000
Category : Medicine
ISBN : OSU:32436010864831

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Cumulated Index Medicus by Anonim Pdf

Structure of Antigens

Author : Marc H. V. Van Regenmortel
Publisher : CRC Press
Page : 444 pages
File Size : 49,5 Mb
Release : 1995-12-20
Category : Medical
ISBN : 084939225X

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Structure of Antigens by Marc H. V. Van Regenmortel Pdf

Volume 3 of Structure of Antigens presents analytical methods used to elucidate the structure of antigens. As in the first two volumes, this reference focuses on the structure and analysis of antibody binding sites. It brings together the structural basis of major types of antigens, including lysozyme, cytochrome c, muscle proteins, cereal and milk proteins, carbohydrate antigens, and more. Major groups of antigens associated with particular biological systems, such as the cytoskeleton, muscle proteins, and viral antigens, are discussed. This reference analyzes the molecular basis of antibody specificity and the structure of T cell epitopes.

Biopolymers: Advances in Research and Application: 2011 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 49 pages
File Size : 47,9 Mb
Release : 2012-01-09
Category : Technology & Engineering
ISBN : 9781464940675

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Biopolymers: Advances in Research and Application: 2011 Edition by Anonim Pdf

Biopolymers: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Biopolymers in a concise format. The editors have built Biopolymers: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biopolymers in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Biopolymers: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Plant Microtubules

Author : Peter Nick
Publisher : Springer
Page : 269 pages
File Size : 52,9 Mb
Release : 2010-10-28
Category : Science
ISBN : 3642095887

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Plant Microtubules by Peter Nick Pdf

Since the publication of the first edition of Plant Microtubules in 2000, our understanding of microtubules and their manifold functions have advanced substantially. This revised edition highlights the morphogenetic potential of plant microtubules from three general viewpoints: Microtubules and Morphogenesis, Microtubules and Environment, Microtubules and Evolution. The book is an invaluable source of information for researchers as well as for graduate and advanced students.