Iron Catalyzed Synthesis Of Fused Aromatic Compounds Via C H Bond Activation

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Iron-Catalyzed Synthesis of Fused Aromatic Compounds via C–H Bond Activation

Author : Arimasa Matsumoto
Publisher : Springer
Page : 84 pages
File Size : 46,9 Mb
Release : 2014-07-08
Category : Science
ISBN : 9784431549284

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Iron-Catalyzed Synthesis of Fused Aromatic Compounds via C–H Bond Activation by Arimasa Matsumoto Pdf

Iron catalysts in organic synthesis are strongly in demand because iron is non-toxic, inexpensive and the most abundant transition metal in the earth, although their use is still limited compared with that of rare, precious metals such as palladium, ruthenium and rhodium. This thesis describes the first practical example of iron catalysis in the carbon–hydrogen bond activation reaction to synthesized fused aromatic ring compounds. By using a unique combination of iron catalyst and dichloride oxidant, various kind of naphthalene and phenanthrene derivatives were synthesized via annulation reaction with alkynes including direct C–H bond activation process. This achievement opens the new possibility of low-valent iron catalysis and expands synthetic methods for a sustainable society.

C-H Bond Activation and Catalytic Functionalization I

Author : Pierre H. Dixneuf,Henri Doucet
Publisher : Springer
Page : 264 pages
File Size : 45,9 Mb
Release : 2015-12-18
Category : Science
ISBN : 9783319246307

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C-H Bond Activation and Catalytic Functionalization I by Pierre H. Dixneuf,Henri Doucet Pdf

The series Topics in Organometallic Chemistry presents critical overviews of research results in organometallic chemistry. As our understanding of organometallic structure, properties and mechanisms increases, new ways are opened for the design of organometallic compounds and reactions tailored to the needs of such diverse areas as organic synthesis, medical research, biology and materials science. Thus the scope of coverage includes a broad range of topics of pure and applied organometallic chemistry, where new breakthroughs are being achieved that are of significance to a larger scientific audience. The individual volumes of Topics in Organometallic Chemistry are thematic. Review articles are generally invited by the volume editors. All chapters from Topics in Organometallic Chemistry are published OnlineFirst with an individual DOI. In references, Topics in Organometallic Chemistry is abbreviated as Top Organomet Chem and cited as a journal.

Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, 2 Volumes

Author : Tharmalingam Punniyamurthy,Anil Kumar
Publisher : John Wiley & Sons
Page : 1209 pages
File Size : 50,8 Mb
Release : 2023-03-28
Category : Science
ISBN : 9781119774150

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Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, 2 Volumes by Tharmalingam Punniyamurthy,Anil Kumar Pdf

Transition-Metal-Catalyzed C-H Functionalization of Heterocycles A comprehensive guide to recent advances in this field Constituting the majority of all known compounds, heterocycles are structures that incorporate one or more heteroatoms within their core, thus exhibiting properties that are quite different from their all-carbon analogs. They are fundamental to all fields of chemistry and, therefore, their synthesis and modification has attracted a great deal of attention in the recent years. In this vein, transition-metal-catalyzed C-H bond functionalization forms a crucial tool for generating and analyzing heterocyclic compounds. Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume Set, showcases diverse C-H functionalization methodologies and their incorporation into the latest research. The chapters serve as an essential tool depicting detailed site-selective functionalization of heterocyclic cores, along with a comprehensive discussion on their mechanistic approaches. Readers of Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume-Set will also find: A detailed introduction to C-H activation along with the mechanistic aspects of transition-metal-catalyzed C-H bond activation reactions Easy-to-use structures with each chapter dedicated to a type of heterocycle and its specific functionalization methodologies A leading team of international authors in C-H bond functionalization Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume-Set is a valuable guide for students and researchers in organic synthesis and process development, in both academic and industrial contexts.

Palladium Assisted Synthesis of Heterocycles

Author : Navjeet Kaur
Publisher : CRC Press
Page : 432 pages
File Size : 40,5 Mb
Release : 2019-05-01
Category : Medical
ISBN : 9781351242608

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Palladium Assisted Synthesis of Heterocycles by Navjeet Kaur Pdf

This book is a compilation of the recent applications of palladium catalysts in organic synthesis. The book demonstrates that it is a highly dynamic research field. This methodology has emerged as a powerful tool for the efficient and chemoselective synthesis of heterocyclic molecules. In the past few years, several strategies have been pointed out to pursue more efficient, sustainable, and environment friendly chemical processes. Among those strategies, catalysis and the design of new processes that avoid the use of toxic reagents have been the focus of intense research.

Heterocycles via Cross Dehydrogenative Coupling

Author : Ananya Srivastava,Chandan K. Jana
Publisher : Springer Nature
Page : 494 pages
File Size : 43,8 Mb
Release : 2019-08-23
Category : Science
ISBN : 9789811391446

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Heterocycles via Cross Dehydrogenative Coupling by Ananya Srivastava,Chandan K. Jana Pdf

This book discusses the developments in the synthesis and functionalization of different heterocycles based on the formation of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds using cross-dehydrogenative coupling (CDC). Consisting of 13 chapters, the book systematically describes the advances in the synthesis and functionalization of nitrogen, oxygen, and sulfur-containing heterocycles. It also discusses the various mechanistic pathways to help readers gain an in-depth understanding of the CDC reactions of heterocycles. Lastly, in order to promote green chemistry, it addresses a range of metal-free CDC reactions of heterocycles – an area that has attracted significant attention in both academic and industrial research.

Green Techniques for Organic Synthesis and Medicinal Chemistry

Author : Wei Zhang,Berkeley W. Cue
Publisher : John Wiley & Sons
Page : 769 pages
File Size : 40,6 Mb
Release : 2012-05-10
Category : Science
ISBN : 9781118308653

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Green Techniques for Organic Synthesis and Medicinal Chemistry by Wei Zhang,Berkeley W. Cue Pdf

An updated overview of the rapidly developing field of green engineering techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.

Recent Advances in Organometallic Chemistry

Author : Azaj Ansari,Vinod Kumar
Publisher : Elsevier
Page : 447 pages
File Size : 40,6 Mb
Release : 2024-04-19
Category : Science
ISBN : 9780323907194

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Recent Advances in Organometallic Chemistry by Azaj Ansari,Vinod Kumar Pdf

Recent Advances in Organometallic Chemistry: Synthetic, Mechanistic and Medicinal Perspective highlights recent advancements in the field of organometallic chemistry. Containing essential information for researchers and advanced-level students, especially those working in chemical synthesis, the book describes the role of organometallic compounds in different combinations in organic synthesis and pharmaceuticals as well as discussing spectral, magnetic and sensing features of the compounds. Including the role of computational investigations towards the mechanistic study of biomimic complexes in catalytic transformation reactions, the book provides a large number of examples along with their leading applications in other fields.Each chapter covers basic strategies, which are illustrated along with examples of the latest advancements in the field and in-depth explanations. Covers the basics of bonding, synthesis and properties of organometallic compounds Includes the role of computational chemistry and magnetochemistry Features recent developments with examples and applications

C-H Bond Activation and Catalytic Functionalization II

Author : Pierre H. Dixneuf,Henri Doucet
Publisher : Springer
Page : 212 pages
File Size : 53,7 Mb
Release : 2016-03-10
Category : Science
ISBN : 9783319293196

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C-H Bond Activation and Catalytic Functionalization II by Pierre H. Dixneuf,Henri Doucet Pdf

The series Topics in Organometallic Chemistry presents critical overviews of research results in organometallic chemistry. As our understanding of organometallic structure, properties and mechanisms increases, new ways are opened for the design of organometallic compounds and reactions tailored to the needs of such diverse areas as organic synthesis, medical research, biology and materials science. Thus the scope of coverage includes a broad range of topics of pure and applied organometallic chemistry, where new breakthroughs are being achieved that are of significance to a larger scientific audience. The individual volumes of Topics in Organometallic Chemistry are thematic. Review articles are generally invited by the volume editors. All chapters from Topics in Organometallic Chemistry are published OnlineFirst with an individual DOI. In references, Topics in Organometallic Chemistry is abbreviated as Top Organomet Chem and cited as a journal.

Arene Chemistry

Author : Jacques Mortier
Publisher : John Wiley & Sons
Page : 992 pages
File Size : 45,7 Mb
Release : 2015-11-30
Category : Science
ISBN : 9781118754986

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Arene Chemistry by Jacques Mortier Pdf

Organized to enable students and synthetic chemists to understand and expand on aromatic reactions covered in foundation courses, the book offers a thorough and accessible mechanistic explanation of aromatic reactions involving arene compounds. • Surveys methods used for preparing arene compounds and their transformations • Connects reactivity and methodology with mechanism • Helps readers apply aromatic reactions in a practical context by designing syntheses • Provides essential information about techniques used to determine reaction mechanisms

C-C Bond Activation

Author : Guangbin Dong
Publisher : Springer
Page : 262 pages
File Size : 43,9 Mb
Release : 2014-09-18
Category : Science
ISBN : 9783642550553

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C-C Bond Activation by Guangbin Dong Pdf

The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. Review articles for the individual volumes are invited by the volume editors. Readership: research chemists at universities or in industry, graduate students

Aromatic C(sp2)−H Dehydrogenative Coupling Reactions

Author : Bagher Eftekhari-Sis
Publisher : CRC Press
Page : 290 pages
File Size : 55,8 Mb
Release : 2019-10-31
Category : Science
ISBN : 9781000733914

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Aromatic C(sp2)−H Dehydrogenative Coupling Reactions by Bagher Eftekhari-Sis Pdf

This comprehensive text covers the research and development trends in the growing field of aromatic C–H dehydrogenative coupling reactions, leading to different types of heterocycles. The author provides answers to how these coupling reactions occur, what kinds of heterocycles are synthesized, and what their advantages are. The palladium-, rhodium-, iridium-, copper-, cobalt-, ruthenium-, and ferric-catalyzed aromatic C(sp2)–H dehydrogenative cross-coupling reactions are described in detail. A useful reference source for researchers and graduates in the field of heterocyclic chemistry and transition-metal-catalyzed dehydrogenative coupling reactions. Features: Comprehensive volume on the synthesis of benzo-heterocycles via aromatic C(sp2)–H bond activation. Heterocycles are of paramount importance to medicinal chemistry and drug discovery. Provides a comprehensive literature survey on the construction of heterocycles. Reaction procedures and mechanistic explanations are included, which will appeal to those in fine chemicals and pharmaceutical companies.

C-H Activation for Asymmetric Synthesis

Author : Françoise Colobert,Joanna Wencel-Delord
Publisher : John Wiley & Sons
Page : 294 pages
File Size : 44,8 Mb
Release : 2019-11-11
Category : Science
ISBN : 9783527343409

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C-H Activation for Asymmetric Synthesis by Françoise Colobert,Joanna Wencel-Delord Pdf

Provides, in one handbook, comprehensive coverage of one of the hottest topics in stereoselective chemistry Written by leading international authors in the field, this book introduces readers to C-H activation in asymmetric synthesis along with all of its facets. It presents stereoselective C-H functionalization with a broad coverage, from outer-sphere to inner-sphere C-H bond activation, and from the control of olefin geometry to the induction of point, planar and axial chirality. Moreover, methods wherein asymmetry is introduced either during the C-H activation or in a different elementary step are discussed. Presented in two parts?asymmetric activation of C(sp3)-H bonds and stereoselective synthesis implying activation of C(sp2)-H bonds?CH-Activation for Asymmetric Synthesis showcases the diversity of stereogenic elements, which can now be constructed by C-H activation methods. Chapters in Part 1 cover: C(sp3)-H bond insertion by metal carbenoids and nitrenoids; stereoselective C-C bond and C-N bond forming reactions through C(sp3)?H bond insertion of metal nitrenoids; enantioselective intra- and intermolecular couplings; and more. Part 2 looks at: C-H activation involved in stereodiscriminant step; planar chirality; diastereoselective formation of alkenes through C(sp2)?H bond activation; amongst other methods. -Covers one of the most rapidly developing fields in organic synthesis and catalysis -Clearly structured in two parts (activation of sp3- and activation of sp2-H bonds) -Edited by two leading experts in C-H activation in asymmetric synthesis CH-Activation for Asymmetric Synthesis will be of high interest to chemists in academia, as well as those in the pharmaceutical and agrochemical industry.

Organic Synthesis

Author : Belakatte Parameshwarappa Nandeshwarappa
Publisher : BoD – Books on Demand
Page : 250 pages
File Size : 55,6 Mb
Release : 2020-05-27
Category : Science
ISBN : 9781789859430

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Organic Synthesis by Belakatte Parameshwarappa Nandeshwarappa Pdf

The book ‘Organic Synthesis - A Nascent Relook’ is a compendium of the recent progress in all aspects of organic chemistry including bioorganic chemistry, organo-metallic chemistry, asymmetric synthesis, heterocyclic chemistry, natural product chemistry, catalytic, green chemistry and medicinal chemistry, polymer chemistry, as well as analytical methods in organic chemistry. The book presents the latest developments in these fields. The chapters are written by chosen experts who are internationally known for their eminent research contributions. Organic synthesis is the complete chemical synthesis of a target molecule. In this book, special emphasis is given to the synthesis of various bioactive heterocycles. Careful selection of various topics in this book will serve the rightful purpose for the chemistry community and the industrial houses at all levels.

Multicomponent Reactions towards Heterocycles

Author : Erik Van der Eycken,Upendra K. Sharma
Publisher : John Wiley & Sons
Page : 626 pages
File Size : 42,5 Mb
Release : 2022-03-21
Category : Science
ISBN : 9783527349081

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Multicomponent Reactions towards Heterocycles by Erik Van der Eycken,Upendra K. Sharma Pdf

Presents a wide-ranging overview of essential topics and recent advances in MCR chemistry Heterocycles are a central component in natural product chemistry, pharmaceuticals, agrochemicals, and material science. New synthetic methodologies integrating the sequencing of multicomponent reactions (MCRs) are today being used for the rapid synthesis of diversified heterocycles in just one step. Multicomponent Reactions towards Heterocycles presents an up-to-date summary MCR chemistry with a focus on the conjugation between modern synthetic methodologies and MCRs. Featuring contributions by leaders in the field, this comprehensive resource highlights applications of MCRs in natural products and intermediate synthesis, discusses current trends and future prospects in MCR chemistry, outlines novel multicomponent procedures, and more. The authors provide the practical information required for designing new reaction strategies and mechanisms, covering topics including MCR-based green synthetic methods, cyclization and cycloaddition reactions, heterocycle multicomponent syntheses in a continuous flow, catalytic alkynoyl generation, MCR synthesis of saturated heterocycles, and C–H functionalization and multicomponent reactions. Provides a thorough overview of heterocycles as input in multicomponent reactions Discusses recent advances in the field of MCR chemistry and progress in the synthesis and functionalization of heterocycles Demonstrates the use of MCRs to simplify synthetic design and achieve complexity and diversity in novel bioactive molecules Highlights examples of multicomponent polymerizations, target-oriented synthesis, and applications of MCR in medicinal chemistry Explains the methodology of using on-resin MCRs to produce heterocycle compounds Illustrating the key role of MCRs towards heterocycles in natural product synthesis, drug discovery, organic synthesis, and other applications, Multicomponent Reactions towards Heterocycles is required reading for synthetic chemists in academia and industry alike.