Kidney Development Disease Repair And Regeneration

Kidney Development Disease Repair And Regeneration Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Kidney Development Disease Repair And Regeneration book. This book definitely worth reading, it is an incredibly well-written.

Kidney Development, Disease, Repair and Regeneration

Melissa Helen Little
Kidney Development Disease Repair and Regeneration Book PDF

Author : Melissa Helen Little
Publisher : Academic Press
Page : 614 pages
File Size : 45,5 Mb
Release : 2015-08-06
Category : Medical
ISBN : 9780128004388

Get Book

Kidney Development, Disease, Repair and Regeneration by Melissa Helen Little Pdf

Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers across experimental nephrology and developmental biology will find this a key reference for learning how the underlying developmental mechanisms of the kidney will lead to greater advances in regenerative medicine within nephrology. Offers researchers a single comprehensive resource written by leaders from both the developmental biology and the experimental nephrology communities Focuses on understanding the molecular basis of organogenesis in the kidney as well as how this can be affected both genetically and environmentally Explains the underlying developmental mechanisms which influence the kidney’s inherent repair capacity Demonstrates how a deeper understanding of mechanisms will lead to greater advances in regenerative medicine

Kidney Development and Disease

Rachel K. Miller
Kidney Development and Disease Book PDF

Author : Rachel K. Miller
Publisher : Springer
Page : 372 pages
File Size : 46,6 Mb
Release : 2017-04-13
Category : Science
ISBN : 9783319514369

Get Book

Kidney Development and Disease by Rachel K. Miller Pdf

Kidney Development and Disease brings together established and young investigators who are leading authorities in nephrology to describe recent advances in three primary areas of research. The first section describes the use of animal models as powerful tools for the discovery of numerous molecular mechanisms regulating kidney development. The second section focuses on nephric cell renewal and differentiation, which lead to diverse cell fates within the developing kidney, and discusses diseases resulting from the aberrant regulation of the balance between cell fate decisions. The final section concentrates on morphogenesis of the developing kidney and its maintenance after formation as well as the diseases resulting from failures in these processes. Kidney form and function have been extensively studied for centuries, leading to discoveries related to their development and disease. Recent scientific advances in molecular and imaging techniques have broadened our understanding of nephron development and maintenance as well as the diseases related to these processes.

Regenerative Nephrology

Michael S. Goligorsky
Regenerative Nephrology Book PDF

Author : Michael S. Goligorsky
Publisher : Academic Press
Page : 442 pages
File Size : 52,6 Mb
Release : 2010-11-26
Category : Science
ISBN : 0123809290

Get Book

Regenerative Nephrology by Michael S. Goligorsky Pdf

Progression of chronic diseases in general and chronic kidney disease in particular has been traditionally viewed in the light of various contributors to development of glomerulosclerosis and tubulointerstitial scarring culminating in renal fibrosis. Indeed, this dogma prevailed for decades underscoring experimental attempts to halt fibrotic processes. Breakthrough investigations of the past few years on stem/progenitor cell involvement in organ regeneration caused a conceptual shift in tackling the mechanisms of nephrosclerosis. It has become clear that the rate of progression of chronic kidney disease is the net sum of the opposing trends: degenerative fibrotic processes and regenerative repair mechanisms. The latter part of this equation has been by and large ignored for years and only recently attracted investigative attention. This book revisits the problem of kidney disease by focusing on regenerative mechanisms in renal repair and on the ways these regenerative processes can become subverted by an intrinsic disease process eventuating in its progression. Cutting-edge investigations are summarized by the most experienced international team of experts. Presents a comprehensive, translational source for all aspects of renal stem cells, tissue regeneration, and stem cell therapies for renal diseases in one reference work. This will ultimately result in time savings for academic, medical and pharma researchers Experts in the renal stem cell system in kidney repair and regeneration take readers from the bench research to new therapeutic approaches, providing a common language for nephrology researchers, fellows and other stem cell researchers. This enables the discussion of development of stem cells and their use in the repair and regeneration of the kidney

Kidney Development

Odyssé Michos
Kidney Development Book PDF

Author : Odyssé Michos
Publisher : Humana Press
Page : 0 pages
File Size : 50,7 Mb
Release : 2012-05-27
Category : Science
ISBN : 1617798509

Get Book

Kidney Development by Odyssé Michos Pdf

Over the last decade the development of new molecular biology tools, advanced microscopy, live imaging and systems biology approaches have revolutionized our conception of how embryonic development proceeds. One fundamental aspect of development biology is the concept of morphogenesis: understanding how a group of multipotent cells organize and differentiate into a complex organ. In Kidney Development: Methods and Protocols, expert researchers in the field detail different approaches to tackle kidney development. These approaches include culture and live imaging aspects of kidney development, analyzing the 3-dimensional aspects of branching morphogenesis as well as nephrogenesis, manipulation of the gene/protein expression during kidney development as well as in the adult kidney, and how to assess kidney malformation and disease. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Kidney Development: Methods and Protocols seeks to aid scientists in the further study of the process of morphogenesis which is fundamental important not only for studying developmental biology but also for regenerative medicine.

Oxford Textbook of Clinical Nephrology

Neil N. Turner,Norbert Lameire,David J. Goldsmith,Christopher G. Winearls,Jonathan Himmelfarb,Giuseppe Remuzzi
Oxford Textbook of Clinical Nephrology Book PDF

Author : Neil N. Turner,Norbert Lameire,David J. Goldsmith,Christopher G. Winearls,Jonathan Himmelfarb,Giuseppe Remuzzi
Publisher : Oxford University Press
Page : 3045 pages
File Size : 47,9 Mb
Release : 2015-10-29
Category : Medical
ISBN : 9780191017650

Get Book

Oxford Textbook of Clinical Nephrology by Neil N. Turner,Norbert Lameire,David J. Goldsmith,Christopher G. Winearls,Jonathan Himmelfarb,Giuseppe Remuzzi Pdf

This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts. The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field. This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasis throughout is on marrying advances in scientific research with clinical management. Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrology's position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence. This print edition of The Oxford Textbook of Clinical Nephrology comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.

Clinical Regenerative Medicine in Urology

Bup Wan Kim
Clinical Regenerative Medicine in Urology Book PDF

Author : Bup Wan Kim
Publisher : Springer
Page : 285 pages
File Size : 42,8 Mb
Release : 2017-09-14
Category : Medical
ISBN : 9789811027239

Get Book

Clinical Regenerative Medicine in Urology by Bup Wan Kim Pdf

This multidisciplinary book provides up-to-date information on clinical approaches that combine stem or progenitor cells, biomaterials and scaffolds, growth factors, and other bioactive agents in order to offer improved treatment of urologic disorders including lower urinary tract dysfunction, urinary incontinence, neurogenic bladder, and erectile dysfunction. In providing clinicians and researchers with a broad perspective on the development of regenerative medicine technologies, it will assist in the dissemination of both regenerative medicine principles and a variety of exciting therapeutic options. After an opening section addressing current developments and future perspectives in tissue engineering and regenerative medicine, fundamentals such as cell technologies, biomaterials, bioreactors, bioprinting, and decellularization are covered in detail. The remainder of the book is devoted to the description and evaluation of a range of cell and tissue applications, with individual chapters focusing on the kidney, bladder, urethra, urethral sphincter, and penis and testis.

Kidney Inflammation, Injury and Regeneration

Patrick C. Baer,Benjamin Koch,Helmut Geiger
Kidney Inflammation Injury and Regeneration Book PDF

Author : Patrick C. Baer,Benjamin Koch,Helmut Geiger
Publisher : MDPI
Page : 496 pages
File Size : 49,7 Mb
Release : 2020-04-03
Category : Medical
ISBN : 9783039285389

Get Book

Kidney Inflammation, Injury and Regeneration by Patrick C. Baer,Benjamin Koch,Helmut Geiger Pdf

Acute kidney injury (AKI) is still associated with high morbidity and mortality incidence rates, and also bears an elevated risk of subsequent chronic kidney disease. Although the kidney has a remarkable capacity for regeneration after injury and may recover completely depending on the type of renal lesions, the options for clinical intervention are restricted to fluid management and extracorporeal kidney support. The development of novel therapies to prevent AKI, to improve renal regeneration capacity after AKI, and to preserve renal function is urgently needed. The Special Issue covers research articles that investigated the molecular mechanisms of inflammation and injury during different renal pathologies, renal regeneration, diagnostics using new biomarkers, and the effects of different stimuli like medication or bacterial components on isolated renal cells or in vivo models. The Special Issue contains important reviews that consider the current knowledge of cell death and regeneration, inflammation, and the molecular mechanisms of kidney diseases. In addition, the potential of cell-based therapy approaches that use mesenchymal stromal/stem cells or their derivates is summarized. This edition is complemented by reviews that deal with the current data situation on other specific topics like diabetes and diabetic nephropathy or new therapeutic targets.

Stocker and Dehner's Pediatric Pathology

Aliya N Husain,Louis P Dehner
Stocker and Dehner s Pediatric Pathology Book PDF

Author : Aliya N Husain,Louis P Dehner
Publisher : Lippincott Williams & Wilkins
Page : 4583 pages
File Size : 54,6 Mb
Release : 2021-04-06
Category : Medical
ISBN : 9781975144838

Get Book

Stocker and Dehner's Pediatric Pathology by Aliya N Husain,Louis P Dehner Pdf

Virtually all aspects of the pathology in children are unique in pathogenesis and histogenesis from the moment of conception to adolescence whose range includes developmental anomalies to dysembryonic neoplasms. Stocker and Dehner’s Pediatric Pathology provides encyclopedic but very usable coverage of this complex subspecialty, detailing all major aspects of the pathologic anatomy of childhood disorders ranging from chromosomal syndromes and infections to forensic pathology. Upholding the standard of excellence established in previous editions, this thoroughly updated Fifth Edition offers the in-depth, richly illustrated guidance you need to confidently evaluate and dependably report your findings.

Cardiorenal Syndromes in Critical Care

C. Ronco,R. Bellomo,P.A. McCullough
Cardiorenal Syndromes in Critical Care Book PDF

Author : C. Ronco,R. Bellomo,P.A. McCullough
Publisher : Karger Medical and Scientific Publishers
Page : 377 pages
File Size : 53,8 Mb
Release : 2010-05-04
Category : Medical
ISBN : 9783805594738

Get Book

Cardiorenal Syndromes in Critical Care by C. Ronco,R. Bellomo,P.A. McCullough Pdf

Critical care nephrology is an emerging multidisciplinary science in which the competences of different specialists are merged to provide a unified diagnostic and therapeutic approach to the critically ill patient. The volume at hand places great emphasis on cardiorenal syndromes and the multidisciplinary collaboration between cardiology and nephrology. Several contributions describe the cardiorenal syndrome in its different varieties and subtypes and report the results from the most recent Acute Dialysis Quality Initiative Consensus Conference, as well as proposing new diagnostic approaches based on early biomarkers of AKI. Other papers discuss advances in technology for renal replacement therapy and multiple organ support therapy. Moreover, special emphasis is placed on the potential role of extracorporeal therapies in patients affected by H1N1 influenza, and a summary of the most recent trials in the field is included.Containing the proceedings of the 2010 International Vicenza Course on Critical Care Nephrology, this publication is a state-of-the-art appraisal of today’s technology and current issues related to cardiorenal syndromes.

Principles of Regenerative Medicine

Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
Principles of Regenerative Medicine Book PDF

Author : Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
Publisher : Academic Press
Page : 1202 pages
File Size : 55,6 Mb
Release : 2010-12-16
Category : Science
ISBN : 0123814235

Get Book

Principles of Regenerative Medicine by Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem Pdf

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

Silva's Diagnostic Renal Pathology

Xin J. Zhou,Zoltan G. Laszik,Tibor Nadasdy,Vivette D. D'Agati
Silva s Diagnostic Renal Pathology Book PDF

Author : Xin J. Zhou,Zoltan G. Laszik,Tibor Nadasdy,Vivette D. D'Agati
Publisher : Cambridge University Press
Page : 691 pages
File Size : 46,9 Mb
Release : 2017-03-02
Category : Medical
ISBN : 9781316613986

Get Book

Silva's Diagnostic Renal Pathology by Xin J. Zhou,Zoltan G. Laszik,Tibor Nadasdy,Vivette D. D'Agati Pdf

An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.

Stem Cells and the Future of Regenerative Medicine

Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research
Stem Cells and the Future of Regenerative Medicine Book PDF

Author : Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research
Publisher : National Academies Press
Page : 112 pages
File Size : 54,8 Mb
Release : 2002-01-25
Category : Science
ISBN : 9780309170420

Get Book

Stem Cells and the Future of Regenerative Medicine by Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research Pdf

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Organ Tissue Engineering

Daniel Eberli,Sang Jin Lee,Andreas Traweger
Organ Tissue Engineering Book PDF

Author : Daniel Eberli,Sang Jin Lee,Andreas Traweger
Publisher : Springer
Page : 0 pages
File Size : 53,8 Mb
Release : 2021-04-22
Category : Technology & Engineering
ISBN : 3030442101

Get Book

Organ Tissue Engineering by Daniel Eberli,Sang Jin Lee,Andreas Traweger Pdf

The notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.

Introduction to Epigenetics

Renato Paro,Ueli Grossniklaus,Raffaella Santoro,Anton Wutz
Introduction to Epigenetics Book PDF

Author : Renato Paro,Ueli Grossniklaus,Raffaella Santoro,Anton Wutz
Publisher : Springer Nature
Page : 215 pages
File Size : 55,6 Mb
Release : 2021-03-23
Category : Science
ISBN : 9783030686703

Get Book

Introduction to Epigenetics by Renato Paro,Ueli Grossniklaus,Raffaella Santoro,Anton Wutz Pdf

This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease

Kidney Transplantation, Bioengineering, and Regeneration

Giuseppe Orlando,Giuseppe Remuzzi,David F. Williams
Kidney Transplantation Bioengineering and Regeneration Book PDF

Author : Giuseppe Orlando,Giuseppe Remuzzi,David F. Williams
Publisher : Academic Press
Page : 1252 pages
File Size : 45,5 Mb
Release : 2017-06-08
Category : Science
ISBN : 9780128018361

Get Book

Kidney Transplantation, Bioengineering, and Regeneration by Giuseppe Orlando,Giuseppe Remuzzi,David F. Williams Pdf

Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era investigates how the field of regenerative medicine is changing the traditional premises of solid organ transplantation, specifically within the field of kidney transplantation. In Section 1, chapters illustrate the state of the art in kidney transplantation as well as the research behind the bioengineering and regeneration of kidney organoids for therapeutic renal replacement. In Section II, chapters catalog the technologies that are being developed and the methods that are being implemented to bioengineer or regenerate kidneys in order to restore function, while critically highlighting those technological advances which hold the most promise. The book thus encompasses clinical renal transplantation, tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, as they are all applied to the kidney. Focuses on the synergy between renal organ transplantation and regenerative medicine, highlighting the advances within transplantation, bioengineering, regeneration, and repair Educates the transplant community on important regenerative medicine research pertinent to kidney transplantation Develops a shared language for clinicians, surgeons, and basic researchers to reach across the fields of transplantation and regenerative medicine, and facilitate more productive investigation and research Catalogs the technologies being developed and methods being implemented to bioengineer or regenerate kidneys to restore function