Male Fertility And Its Regulation

Author : E.S. Hafez,T.J. Lobl
Publisher : Springer Science & Business Media
Page : 474 pages
File Size : 45,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400948945

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Male Fertility and Its Regulation by E.S. Hafez,T.J. Lobl Pdf

Uncontrolled population growth, a significant problem for many countries, depresses real living standards in all developing areas. As a corollary, un controlled population growth also stresses the ability to deliver adequate reproductive health care on both national and individual levels. To focus on this and related problems an International Congress to examine many aspects of male and female Reproductive Health Center Care was held on 10-15 October 1982 in Maui, Hawaii, USA. This volume is a result of the proceedings from the 'Symposium on Male Fertility and its Regulation' which was a part of the Reproductive Health Care Congress. The organizers of this symposium recognized the need to focus male reproductive understanding on contraceptive development. The ultimate objective was and still is to produce a variety of safe and effective male contraceptives similar to that accomplished in the female. Speakers were invited to review the state of the art in several areas related to male contra ception, reproductive toxicity and reproductive biology. The abstracts of these sessions were published as a special issue of Archives of Andrology (Vol. 9, No.1, August, 1982). Subsequently, this volume was assembled from key papers presented at the Symposium. Additionally, invited man uscripts from leaders in specific areas were solicited to provide additional range to the topics covered.

Author : Giorgio Cavallini,Giovanni Beretta
Publisher : Springer
Page : 187 pages
File Size : 40,6 Mb
Release : 2014-10-20
Category : Health & Fitness
ISBN : 9783319085036

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Clinical Management of Male Infertility by Giorgio Cavallini,Giovanni Beretta Pdf

This book provides andrologists and other practitioners with reliable, up-to-date information on all aspects of male infertility and is designed to assist in the clinical management of patients. Clear guidance is offered on classification of infertility, sperm analysis interpretation and diagnosis. The full range of types and causes of male infertility are then discussed in depth. Particular attention is devoted to poorly understood conditions such as unexplained couple infertility and idiopathic male infertility, but the roles of diverse disorders, health and lifestyle factors and environmental pollution are also fully explored. Research considered stimulating for the reader is highlighted, reflecting the fascinating and controversial nature of the field. International treatment guidelines are presented and the role of diet and dietary supplements is discussed in view of their increasing importance. Clinicians will find that the book’s straightforward approach ensures that it can be easily and rapidly consulted.

Author : G.R. Cunningham,W.B. Schill,E.S. Hafez
Publisher : Springer Science & Business Media
Page : 229 pages
File Size : 52,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400988750

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Regulation of Male Fertility by G.R. Cunningham,W.B. Schill,E.S. Hafez Pdf

Many of the studies discussed in this book were addition to discussions of a variety of hormonal, presented at the First Pan American Congress of biochemical, immunological, physical, and me Andrology, which was held in Caracas, Venezuela, chanical approaches. It is our hope that the efforts in March 1979. An international group of in of the contributors will help to intensify research vestigators have contributed reviews designed to and development of improved methods for safely be informative to medical, graduate, and post regulating male fertility. graduate students, as well as clinicians and in vestigators working in the area of male reproduc G. R. CUNNINGHAM tion. Current physiological concepts that may W. B. SCHILL provide insight for new initiatives are examined in E. S. E. HAFEZ TABLE OF CONTENTS Preface v Contributors IX Foreword by C. SCHIRREN XI 1. PHYSIOLOGY OF MALE REPRODUCTION 1. Hormonal regulation of testicular function 5 P. FRANCHIMONT 2. Inhibin: new gonadal hormone 15 P. FRANCHIMONT, A. DEMOULIN, J. VERSTRAELEN-PROYARD, M. T. HAZEE-HAGELSTEIN, and J. P. BOURGUIGNON 3. Morphological features of the epididymis: possible significance in male contraception 25 T. D. GLOVER 4. Regulatory physiology of male accessory organs 35 E. S. E. HAFEZ and G. R. CUNNINGHAM 5. Methods for evaluating contraceptive techniques 41 T. Z. HOMONNAI and F. G. PAZ II. HORMONAL CONTRACEPTION 6. Inhibition of male reproductive processes with an LH-RH agonist 55 A. CORBIN and F. J. BEX 7.

Author : Anonim
Publisher : Unknown
Page : 99 pages
File Size : 49,5 Mb
Release : 1982
Category : Electronic
ISBN : OCLC:900817830

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Male Fertility and Its Regulation by Anonim Pdf

Author : World Health Organisation
Publisher : Cambridge University Press
Page : 150 pages
File Size : 48,7 Mb
Release : 1999-05-13
Category : Medical
ISBN : 0521645999

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WHO Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction by World Health Organisation Pdf

The definitive and essential source of reference for all laboratories involved in the analysis of human semen.

Author : Cristian O'Flaherty
Publisher : MDPI
Page : 194 pages
File Size : 54,6 Mb
Release : 2020-12-02
Category : Science
ISBN : 9783039360246

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Reactive Oxygen Species and Male Fertility by Cristian O'Flaherty Pdf

Reactive oxygen species (ROS) are inevitable by-products of aerobic cells. A delicate balance between ROS production and antioxidant defences is essential to assure cell function. This requirement is also true for the spermatozoon, the male gamete, with the unique goal of carrying and delivering the paternal genome into the oocyte. Oxidative stress promotes damage in lipids, proteins and DNA of spermatozoa, and this oxidative damage is associated with infertility. The ROS-dependent damage could occur at different stages of the production and maturation of the sperm. On the other hand, low and controlled levels of ROS are necessary to trigger and regulate sperm function. When ejaculated, spermatozoa are incapable of fertilizing the egg. They must reside in the oviduct of the female genital tract to undergo a yet to be understood the biochemical process called capacitation. Once capacitated, the spermatozoon undergoes the exocytotic event called acrosome reaction and fertilize the oocyte. ROS regulate the different molecular mechanisms such as sperm motility, capacitation and acrosome reaction to assure fertilization. This Special Issue includes original research and reviews of literature concerning the role of reactive oxygen species in male reproduction, particularly the role of antioxidants in the regulation of male fertility as well as basic and clinical studies using antioxidant-based strategies for the treatment of male infertility.

Author : Mohamed Arafa,Haitham Elbardisi,Ahmad Majzoub,Ashok Agarwal
Publisher : Springer Nature
Page : 374 pages
File Size : 48,6 Mb
Release : 2020-03-14
Category : Health & Fitness
ISBN : 9783030379728

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Genetics of Male Infertility by Mohamed Arafa,Haitham Elbardisi,Ahmad Majzoub,Ashok Agarwal Pdf

This unique, case-based guide provides a thoughtful and comprehensive overview of the genetic basis of male infertility for the practicing clinician. In addition to discussing the molecular foundations of sperm production and the consequences of genetic abnormalities on various stages of sperm development, it examines the clinical aspects of acknowledged genetic disorders and their implications on male fertility. In so doing, it offers the necessary tools required by the clinician for the diagnosis and treatment of infertile men with genetic abnormalities. Moreover, it provides essential algorithms that may aid in counseling patients in the clinic. The text is arranged in four thematic sections for easy reference. The genetic foundation of male reproduction is presented in part 1, including regulation of sperm production, the structure of sperm chromatin, and spermatogenesis. The impact of genetic abnormalities on male infertility is the subject of part 2, covering sperm defects, mitochondrial function and DNA fragmentation. The clinical case material in part 3 illustrates real-world examples of genetic etiologies and the current diagnostic and therapeutic strategies for conditions such as vas asplasia, cryptorchidism, immotile cilia syndrome, sperm aneuploidy and other challenging scenarios. Casting forward, the fourth and final section presents an overview of future possibilities for management of genetic causes of male infertility, including gene editing. Fully exploring the clinical context of these genetic conditions in a practical manner that appeals to the practicing clinician, Genetics of Male Infertility is an exciting and essential text for reproductive medicine specialists, andrologists, urologists, researchers and all other clinicians treating infertile patients.

Author : T. D. Glover,C. L. R. Barratt
Publisher : Cambridge University Press
Page : 287 pages
File Size : 43,5 Mb
Release : 2009-03-19
Category : Medical
ISBN : 9781139425704

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Male Fertility and Infertility by T. D. Glover,C. L. R. Barratt Pdf

This contemporary account of male fertility provides a much needed bridge between those seeking to understand the subject from an evolutionary and biological perspective and those with clinical responsibility for the investigation and treatment of infertility. Accordingly, the first half of the book deals with the evolutionary aspects of male reproduction and sperm competition, sperm production and delivery in man and other animals, spermatogenesis and epididymal function, sperm transport in the female tract and the apparent decline in human sperm count. The second part of the book puts greater emphasis on clinical problems and opens with a discussion of intracytoplasmic sperm injection, its value and limitations. This is followed by a review of modern developments in the genetics of male fertility and proceeds to a further chapter on the role of surgical procedures used in the treatment. Semen analysis is critically reviewed and the molecular techniques now being used in preimplantation diagnosis and in the study of mitochondrial inheritance are fully described. Taken together these chapters, written by an international team of authors, illustrate the breadth of vision needed to tackle the problem of male fertility.

Author : Kavindra Kumar Kesari,Shubhadeep Roychoudhury
Publisher : Springer Nature
Page : 384 pages
File Size : 51,9 Mb
Release : 2022-05-31
Category : Medical
ISBN : 9783030893408

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Oxidative Stress and Toxicity in Reproductive Biology and Medicine by Kavindra Kumar Kesari,Shubhadeep Roychoudhury Pdf

This book discusses the role of oxidative stress in human reproduction with a focus on men’s health. The physiological roles of reactive oxygen species (ROS) in male fertility are the focus in this book. This topic is important because oxidative stress is a result of the imbalance between ROS and antioxidants in the body which may lead to sperm damage (DNA or count), deformity, and eventually, male infertility. Therefore, for a better understanding of the molecular mechanisms related to male genotoxicity and its regulation in infertility, this book provides an up-to-date view on the impact of oxidative stress factors in male reproduction . The main aim of this book is to collect a series of research articles and reviews from a diverse group of scientists to share their research work on the role of ROS or oxidative stress in physiological and pathological states in relation to (in)fertility in the male. This book presents various state-of-the-art chapters of the recent progress in the field of cellular toxicology and clinical manifestations of various issues related to men’s health and fertility. Topics include cell signaling, DNA damage and infertility, the pathophysiology of disease instigation and distribution, immune toxicity and prevention.

Author : Shanna H. Swan,Stacey Colino
Publisher : Simon and Schuster
Page : 304 pages
File Size : 46,9 Mb
Release : 2022-02-08
Category : Health & Fitness
ISBN : 9781982113674

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Count Down by Shanna H. Swan,Stacey Colino Pdf

An award-winning scientist, in this urgent, thought-provoking and meticulously researched book, shows how chemicals in the modern environment are changing--and endangering--human sexuality and fertility on the grandest scale.

Author : C.Yan Cheng,Fei Sun
Publisher : Springer
Page : 0 pages
File Size : 40,6 Mb
Release : 2022-08-30
Category : Science
ISBN : 3030777812

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Molecular Mechanisms in Spermatogenesis by C.Yan Cheng,Fei Sun Pdf

This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.

Author : Larry I. Lipshultz,Stuart S. Howards,Craig S. Niederberger
Publisher : Cambridge University Press
Page : 691 pages
File Size : 54,6 Mb
Release : 2009-09-24
Category : Medical
ISBN : 9781139483247

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Infertility in the Male by Larry I. Lipshultz,Stuart S. Howards,Craig S. Niederberger Pdf

The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice – will see men with suboptimal fertility and reproductive problems. The book provides an excellent source of timely, well-considered information for those training in this young and rapidly evolving field. While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. The book has been extensively revised with a particular focus on modern molecular medicine. Appropriate therapeutic interventions are highlighted throughout.

Author : Colin Markland,John J. Sciarra,J. Joseph Speidel
Publisher : Unknown
Page : 316 pages
File Size : 40,6 Mb
Release : 1975
Category : Electronic
ISBN : OCLC:164675873

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Control of male fertility by Colin Markland,John J. Sciarra,J. Joseph Speidel Pdf

Author : P.H. Vogt
Publisher : Karger Medical and Scientific Publishers
Page : 178 pages
File Size : 53,8 Mb
Release : 2017-09-12
Category : Medical
ISBN : 9783318060980

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Genetics of Human Infertility by P.H. Vogt Pdf

Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its complex etiology often, but not always, includes genetic factors besides anatomical defects, immunological interference, and environmental aspects. Nearly 30% of infertility cases are probably caused only by genetic defects. Thereby experimental animal knockout models convincingly show that infertility can be caused by single or multiple gene defects. Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods. This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.

Author : Nicola Fabris
Publisher : Springer Science & Business Media
Page : 473 pages
File Size : 44,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468445473

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Immunoregulation by Nicola Fabris Pdf

Immunoregulation is one of the areas which has witnessed the most explosive advances of immunology during the past decade. It is in this area that the current view of the immune system has arisen and developed. There is indeed little doubt that immune reactions are primarily determined by messages which are genera ted within the immune system and passed among different types of immunologie cells. This cell communication not only determines the type, intensity and duration of the response after perturbation of the immune system by exogenous antigens, but it is also essential for preventing autoimmune reactions and their clinical conse quences. In order to assure aperfect balance within the enormous com plexity of the immune system, it is not surprising that multiple self-regulatory mechanisms are organized at different levels, such as antibody feedback, idiotypic-anti-idiotypic responses, suppres sor and helper T cells, lymphokine signals and genetic require ments. A nu mb er of observations in recent years have, however, demonstrated that consistent contributions to the immunological homeostasis are given also by signals generated outside of the immune system, namely,in the central and autonomous nervous system as weIl as in the endocrine apparatus. Furthermore, the interactions between the immune system and the other body homestatic mechanisms seem to be bidirectional: if immunological cells may be targets of neuroendocrinological factors, immunological products seem in turn to contribute to the neuro endocrine homeostasis.