Mapping Biological Systems To Network Systems

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Mapping Biological Systems to Network Systems

Author : Heena Rathore
Publisher : Springer
Page : 196 pages
File Size : 55,9 Mb
Release : 2016-02-10
Category : Technology & Engineering
ISBN : 9783319297828

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Mapping Biological Systems to Network Systems by Heena Rathore Pdf

The book presents the challenges inherent in the paradigm shift of network systems from static to highly dynamic distributed systems – it proposes solutions that the symbiotic nature of biological systems can provide into altering networking systems to adapt to these changes. The author discuss how biological systems – which have the inherent capabilities of evolving, self-organizing, self-repairing and flourishing with time – are inspiring researchers to take opportunities from the biology domain and map them with the problems faced in network domain. The book revolves around the central idea of bio-inspired systems -- it begins by exploring why biology and computer network research are such a natural match. This is followed by presenting a broad overview of biologically inspired research in network systems -- it is classified by the biological field that inspired each topic and by the area of networking in which that topic lies. Each case elucidates how biological concepts have been most successfully applied in various domains. Nevertheless, it also presents a case study discussing the security aspects of wireless sensor networks and how biological solution stand out in comparison to optimized solutions. Furthermore, it also discusses novel biological solutions for solving problems in diverse engineering domains such as mechanical, electrical, civil, aerospace, energy and agriculture. The readers will not only get proper understanding of the bio inspired systems but also better insight for developing novel bio inspired solutions.

Networks of Networks in Biology

Author : Narsis A. Kiani,David Gomez-Cabrero,Ginestra Bianconi
Publisher : Cambridge University Press
Page : 215 pages
File Size : 50,9 Mb
Release : 2021-04
Category : Computers
ISBN : 9781108428873

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Networks of Networks in Biology by Narsis A. Kiani,David Gomez-Cabrero,Ginestra Bianconi Pdf

Introduces network inspired approaches for the analysis and integration of large, heterogeneous data sets in the life sciences.

Systems Biology for Signaling Networks

Author : Sangdun Choi
Publisher : Springer Science & Business Media
Page : 900 pages
File Size : 54,9 Mb
Release : 2010-08-09
Category : Science
ISBN : 9781441957979

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Systems Biology for Signaling Networks by Sangdun Choi Pdf

System Biology encompasses the knowledge from diverse fields such as Molecular Biology, Immunology, Genetics, Computational Biology, Mathematical Biology, etc. not only to address key questions that are not answerable by individual fields alone, but also to help in our understanding of the complexities of biological systems. Whole genome expression studies have provided us the means of studying the expression of thousands of genes under a particular condition and this technique had been widely used to find out the role of key macromolecules that are involved in biological signaling pathways. However, making sense of the underlying complexity is only possible if we interconnect various signaling pathways into human and computer readable network maps. These maps can then be used to classify and study individual components involved in a particular phenomenon. Apart from transcriptomics, several individual gene studies have resulted in adding to our knowledge of key components that are involved in a signaling pathway. It therefore becomes imperative to take into account of these studies also, while constructing our network maps to highlight the interconnectedness of the entire signaling pathways and the role of that particular individual protein in the pathway. This collection of articles will contain a collection of pioneering work done by scientists working in regulatory signaling networks and the use of large scale gene expression and omics data. The distinctive features of this book would be: Act a single source of information to understand the various components of different signaling network (roadmap of biochemical pathways, the nature of a molecule of interest in a particular pathway, etc.), Serve as a platform to highlight the key findings in this highly volatile and evolving field, and Provide answers to various techniques both related to microarray and cell signaling to the readers.

Recent Advances in Information Systems and Technologies

Author : Álvaro Rocha,Ana Maria Correia,Hojjat Adeli,Luís Paulo Reis,Sandra Costanzo
Publisher : Springer
Page : 1054 pages
File Size : 50,5 Mb
Release : 2017-03-28
Category : Technology & Engineering
ISBN : 9783319565385

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Recent Advances in Information Systems and Technologies by Álvaro Rocha,Ana Maria Correia,Hojjat Adeli,Luís Paulo Reis,Sandra Costanzo Pdf

This book presents a selection of papers from the 2017 World Conference on Information Systems and Technologies (WorldCIST'17), held between the 11st and 13th of April 2017 at Porto Santo Island, Madeira, Portugal. WorldCIST is a global forum for researchers and practitioners to present and discuss recent results and innovations, current trends, professional experiences and challenges involved in modern Information Systems and Technologies research, together with technological developments and applications. The main topics covered are: Information and Knowledge Management; Organizational Models and Information Systems; Software and Systems Modeling; Software Systems, Architectures, Applications and Tools; Multimedia Systems and Applications; Computer Networks, Mobility and Pervasive Systems; Intelligent and Decision Support Systems; Big Data Analytics and Applications; Human–Computer Interaction; Ethics, Computers & Security; Health Informatics; Information Technologies in Education; and Information Technologies in Radiocommunications.

Constraint Decision-Making Systems in Engineering

Author : Das, Santosh Kumar,Dey, Nilanjan
Publisher : IGI Global
Page : 333 pages
File Size : 44,6 Mb
Release : 2023-01-06
Category : Business & Economics
ISBN : 9781668473450

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Constraint Decision-Making Systems in Engineering by Das, Santosh Kumar,Dey, Nilanjan Pdf

In recent years, most applications deal with constraint decision-making systems as problems are based on imprecise information and parameters. It is difficult to understand the nature of data based on applications and it requires a specific model for understanding the nature of the system. Further research on constraint decision-making systems in engineering is required. Constraint Decision-Making Systems in Engineering derives and explores several types of constraint decisions in engineering and focuses on new and innovative conclusions based on problems, robust and efficient systems, and linear and non-linear applications. Covering topics such as fault detection, data mining techniques, and knowledge-based management, this premier reference source is an essential resource for engineers, managers, computer scientists, students and educators of higher education, librarians, researchers, and academicians.

Applied Statistics for Network Biology

Author : Matthias Dehmer,Frank Emmert-Streib,Armin Graber,Armindo Salvador
Publisher : John Wiley & Sons
Page : 441 pages
File Size : 43,9 Mb
Release : 2011-04-08
Category : Medical
ISBN : 9783527638086

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Applied Statistics for Network Biology by Matthias Dehmer,Frank Emmert-Streib,Armin Graber,Armindo Salvador Pdf

The book introduces to the reader a number of cutting edge statistical methods which can e used for the analysis of genomic, proteomic and metabolomic data sets. In particular in the field of systems biology, researchers are trying to analyze as many data as possible in a given biological system (such as a cell or an organ). The appropriate statistical evaluation of these large scale data is critical for the correct interpretation and different experimental approaches require different approaches for the statistical analysis of these data. This book is written by biostatisticians and mathematicians but aimed as a valuable guide for the experimental researcher as well computational biologists who often lack an appropriate background in statistical analysis.

Network Structures in Biological Systems and in Human Society

Author : Alexander V. Oleskin
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 49,9 Mb
Release : 2014
Category : Biological systems
ISBN : 1628085096

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Network Structures in Biological Systems and in Human Society by Alexander V. Oleskin Pdf

This book focuses on network structures in biological systems and in human society. The term "network structure" is used in literature with at least two different meanings. The broader meaning (denoted by this author as a network sensu lato) refers to any system composed of nodes (vertices) connected by links (edges). In terms of this interpretation, the analytical tools that deal with centrality measures, clustering, and community structure-related criteria, small-world behaviour, and other network characteristics have provided important insights into the organisation and functioning of various objects, including biological systems and human society. However, there is a narrower interpretation of the term "network" that is predominantly used in the social sciences: a network structure is a decentralised, non-hierarchical system that is regulated by co-operative interactions among its nodes (a network sensu stricto. In this work, the term "networks" is interpreted in the latter sense. The characteristics of a network's organisational situation are considered in this work in comparison to other types of structures that are denoted as (1) hierarchical (vertical, pyramidal) structures characterised by a single dominant activity centre (central leader, pacemaker); and (2) (quasi-)market structures dominated by competitive, rather than co-operative, interactions among the actors involved. This is an interdisciplinary work because the three organisational structures are considered with respect to biological systems and to human society, including its political system.

An Introduction to Computational Systems Biology

Author : Karthik Raman
Publisher : CRC Press
Page : 359 pages
File Size : 46,6 Mb
Release : 2021-05-30
Category : Computers
ISBN : 9780429944529

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An Introduction to Computational Systems Biology by Karthik Raman Pdf

Emphasises a hands-on approach to modelling Strong emphasis on coding and software tools for systems biology Covers the entire spectrum of modelling, from static networks, to dynamic models Thoughtful exercises to test and enable student understanding of concepts Current chapters on exciting new developments like whole-cell modelling and community modelling

Networks in Systems Biology

Author : Fabricio Alves Barbosa da Silva,Nicolas Carels,Marcelo Trindade dos Santos,Francisco José Pereira Lopes
Publisher : Springer Nature
Page : 381 pages
File Size : 55,9 Mb
Release : 2020-10-03
Category : Computers
ISBN : 9783030518622

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Networks in Systems Biology by Fabricio Alves Barbosa da Silva,Nicolas Carels,Marcelo Trindade dos Santos,Francisco José Pereira Lopes Pdf

This book presents a range of current research topics in biological network modeling, as well as its application in studies on human hosts, pathogens, and diseases. Systems biology is a rapidly expanding field that involves the study of biological systems through the mathematical modeling and analysis of large volumes of biological data. Gathering contributions from renowned experts in the field, some of the topics discussed in depth here include networks in systems biology, the computational modeling of multidrug-resistant bacteria, and systems biology of cancer. Given its scope, the book is intended for researchers, advanced students, and practitioners of systems biology. The chapters are research-oriented, and present some of the latest findings on their respective topics.

Complex Systems Science in Biomedicine

Author : Thomas Deisboeck,J. Yasha Kresh
Publisher : Springer Science & Business Media
Page : 857 pages
File Size : 44,8 Mb
Release : 2007-06-13
Category : Medical
ISBN : 9780387335322

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Complex Systems Science in Biomedicine by Thomas Deisboeck,J. Yasha Kresh Pdf

Complex Systems Science in Biomedicine Thomas S. Deisboeck and J. Yasha Kresh Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts. In Parts I & II, Complex Systems Science in Biomedicine provides a general systems thinking perspective and presents some of the fundamental theoretical underpinnings of this rapidly emerging field. Part III then follows with a multi-scaled approach, spanning from the molecular to macroscopic level, exemplified by studying such diverse areas as molecular networks and developmental processes, the immune and nervous systems, the heart, cancer and multi-organ failure. The volume concludes with Part IV that addresses methods and techniques driven in design and development by this new understanding of biomedical science. Key Topics Include: • Historic Perspectives of General Systems Thinking • Fundamental Methods and Techniques for Studying Complex Dynamical Systems • Applications from Molecular Networks to Disease Processes • Enabling Technologies for Exploration of Systems in the Life Sciences Complex Systems Science in Biomedicine is essential reading for experimental, theoretical, and interdisciplinary scientists working in the biomedical research field interested in a comprehensive overview of this rapidly emerging field. About the Editors: Thomas S. Deisboeck is currently Assistant Professor of Radiology at Massachusetts General Hospital and Harvard Medical School in Boston. An expert in interdisciplinary cancer modeling, Dr. Deisboeck is Director of the Complex Biosystems Modeling Laboratory which is part of the Harvard-MIT Martinos Center for Biomedical Imaging. J. Yasha Kresh is currently Professor of Cardiothoracic Surgery and Research Director, Professor of Medicine and Director of Cardiovascular Biophysics at the Drexel University College of Medicine. An expert in dynamical systems, he holds appointments in the School of Biomedical Engineering and Health Systems, Dept. of Mechanical Engineering and Molecular Pathobiology Program. Prof. Kresh is Fellow of the American College of Cardiology, American Heart Association, Biomedical Engineering Society, American Institute for Medical and Biological Engineering.

Handbook on Biological Networks

Author : Stefano Boccaletti
Publisher : World Scientific
Page : 465 pages
File Size : 53,8 Mb
Release : 2010
Category : Mathematics
ISBN : 9789812838803

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Handbook on Biological Networks by Stefano Boccaletti Pdf

Networked systems are all around us. The accumulated evidence of systems as complex as a cell cannot be fully understood by studying only their isolated constituents, giving rise to a new area of interest in research OCo the study of complex networks . In a broad sense, biological networks have been one of the most studied networks, and the field has benefited from many important contributions. By understanding and modeling the structure of a biological network, a better perception of its dynamical and functional behavior is to be expected. This unique book compiles the most relevant results and novel insights provided by network theory in the biological sciences, ranging from the structure and dynamics of the brain to cellular and protein networks and to population-level biology. Sample Chapter(s). Chapter 1: Introduction (61 KB). Contents: Networks at the Cellular Level: The Structural Network Properties of Biological Systems (M Brilli & P Li); Dynamics of Multicellular Synthetic Gene Networks (E Ullner et al.); Boolean Networks in Inference and Dynamic Modeling of Biological Systems at the Molecular and Physiological Level (J Thakar & R Albert); Complexity of Boolean Dynamics in Simple Models of Signaling Networks and in Real Genetic Networks (A D az-Guilera & R ulvarez-Buylla); Geometry and Topology of Folding Landscapes (L Bongini & L Casetti); Elastic Network Models for Biomolecular Dynamics: Theory and Application to Membrane Proteins and Viruses (T R Lezon et al.); Metabolic Networks (M C Palumbo et al.); Brain Networks: The Human Brain Network (O Sporns); Brain Network Analysis from High-Resolution EEG Signals (F De Vico Fallani & F Babiloni); An Optimization Approach to the Structure of the Neuronal layout of C elegans (A Arenas et al.); Cultured Neuronal Networks Express Complex Patterns of Activity and Morphological Memory (N Raichman et al.); Synchrony and Precise Timing in Complex Neural Networks (R-M Memmesheimer & M Timme); Networks at the Individual and Population Levels: Ideas for Moving Beyond Structure to Dynamics of Ecological Networks (D B Stouffer et al.); Evolutionary Models for Simple Biosystems (F Bagnoli); Evolution of Cooperation in Adaptive Social Networks (S Van Segbroeck et al.); From Animal Collectives and Complex Networks to Decentralized Motion Control Strategies (A Buscarino et al.); Interplay of Network State and Topology in Epidemic Dynamics (T Gross). Readership: Advanced undergraduates, graduate students and researchers interested in the study of complex networks in a wide range of biological processes and systems."

Big Mechanisms in Systems Biology

Author : Bor-Sen Chen,Cheng-Wei Li
Publisher : Academic Press
Page : 878 pages
File Size : 41,6 Mb
Release : 2016-10-25
Category : Medical
ISBN : 9780128097076

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Big Mechanisms in Systems Biology by Bor-Sen Chen,Cheng-Wei Li Pdf

Big Mechanisms in Systems Biology: Big Data Mining, Network Modeling, and Genome-Wide Data Identification explains big mechanisms of systems biology by system identification and big data mining methods using models of biological systems. Systems biology is currently undergoing revolutionary changes in response to the integration of powerful technologies. Faced with a large volume of available literature, complicated mechanisms, small prior knowledge, few classes on the topics, and causal and mechanistic language, this is an ideal resource. This book addresses system immunity, regulation, infection, aging, evolution, and carcinogenesis, which are complicated biological systems with inconsistent findings in existing resources. These inconsistencies may reflect the underlying biology time-varying systems and signal transduction events that are often context-dependent, which raises a significant problem for mechanistic modeling since it is not clear which genes/proteins to include in models or experimental measurements. The book is a valuable resource for bioinformaticians and members of several areas of the biomedical field who are interested in an in-depth understanding on how to process and apply great amounts of biological data to improve research. Written in a didactic manner in order to explain how to investigate Big Mechanisms by big data mining and system identification Provides more than 140 diagrams to illustrate Big Mechanism in systems biology Presents worked examples in each chapter

Cancer Systems Biology

Author : Edwin Wang
Publisher : CRC Press
Page : 456 pages
File Size : 43,5 Mb
Release : 2010-05-04
Category : Computers
ISBN : 1439811865

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Cancer Systems Biology by Edwin Wang Pdf

The unprecedented amount of data produced with high-throughput experimentation forces biologists to employ mathematical representation and computation methods to glean meaningful information in systems-level biology. Applying this approach to the underlying molecular mechanisms of tumorigenesis, cancer researchers can uncover a series of new discov

Methods in Bioengineering

Author : Arul Jayaraman,Juergen Hahn
Publisher : Artech House
Page : 329 pages
File Size : 40,8 Mb
Release : 2009
Category : Science
ISBN : 9781596934061

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Methods in Bioengineering by Arul Jayaraman,Juergen Hahn Pdf

"This cutting-edge volume provides a detailed look at the two main aspects of systems biology: the design of sophisticated experimental methods and the development of complex models to analyze the data. Focusing on methods that are being used to solve current problems in biomedical science and engineering, this comprehensive, richly illustrated resource shows you how to: design of state-of-the art methods for analyzing biological systems Implement experimental approaches for investigating cellular behavior in health and disease; use algorithms and modeling techniques for quantitatively describing biomedical problems; and integrate experimental and computational approaches for a more complete view of biological systems." --Book Jacket.

Guide to Yeast Genetics: Functional Genomics, Proteomics, and Other Systems Analysis

Author : Anonim
Publisher : Academic Press
Page : 942 pages
File Size : 45,6 Mb
Release : 2010-02-27
Category : Science
ISBN : 012375173X

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Guide to Yeast Genetics: Functional Genomics, Proteomics, and Other Systems Analysis by Anonim Pdf

This fully updated edition of the bestselling three-part Methods in Enzymology series, Guide to Yeast Genetics and Molecular Cell Biology is specifically designed to meet the needs of graduate students, postdoctoral students, and researchers by providing all the up-to-date methods necessary to study genes in yeast. Procedures are included that enable newcomers to set up a yeast laboratory and to master basic manipulations. This volume serves as an essential reference for any beginning or experienced researcher in the field. Provides up-to-date methods necessary to study genes in yeast. Includes proceedures that enable newcomers to set up a yeast laboratory and to master basic manipulations. This volume serves as an essential reference for any beginning or experienced researcher in the field.