Mass Spectrometry Based Metabolomics In Clinical And Herbal Medicines

Mass Spectrometry Based Metabolomics In Clinical And Herbal Medicines Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Mass Spectrometry Based Metabolomics In Clinical And Herbal Medicines book. This book definitely worth reading, it is an incredibly well-written.

Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines

Aihua Zhang,Wanying Wang
Mass Spectrometry Based Metabolomics in Clinical and Herbal Medicines Book PDF

Author : Aihua Zhang,Wanying Wang
Publisher : John Wiley & Sons
Page : 292 pages
File Size : 43,8 Mb
Release : 2021-08-20
Category : Science
ISBN : 9783527835744

Get Book

Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines by Aihua Zhang,Wanying Wang Pdf

Highlights the importance and benefit of mass spectrometry-based metabolomics for identifying biomarkers that accurately screen for potential biomarkers of diseases Mass spectrometry-based metabolomics offer new opportunities for biomarker discovery in complex diseases and may provide pathological understanding of diseases beyond traditional technologies. It is the systematic analysis of low-molecular-weight metabolites in biological samples and has been applied to discovering and identifying the perturbed pathways. Currently, mass spectrometry-based metabolomics has become an important tool in clinical research and the diagnosis of human disease. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines comprehensively presents the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics such as metabolites analysis, biomarker discovery, technical challenges, discovery of natural product, mechanism interpretation of action, discovery of active ingredients, clinical application and precision medicine, and enhancing their biomedical value in a real world of biomedicine, shedding light on the potential for spectrometry-based metabolomics. It highlights the value of mass spectrometry-based metabolomics and metabolism to address the complexity of herbal medicines in systems pharmacology, especially, to link phytochemical analysis with the assessment of pharmacological effect and therapeutic potential. Each chapter has been laid out with introduction, method, up-to-date literature, identification of biomarker, and applications Covers the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics in the discovery of biomarker, active ingredients, natural product, etc. Constitutes a unique and indispensable practical guide for any phytochemistry or related laboratory, and provides hands-on description of new techniques Provides a guide for new practitioners of pharmacologists, pharmacological scholars, drug developers, botanist, researchers of traditional medicines. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines provides a landmark of mass spectrometry-based metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all biomedical science fields.

Metabolomics

Xianquan Zhan
Metabolomics Book PDF

Author : Xianquan Zhan
Publisher : BoD – Books on Demand
Page : 170 pages
File Size : 53,7 Mb
Release : 2021-09-01
Category : Science
ISBN : 9781839690839

Get Book

Metabolomics by Xianquan Zhan Pdf

Metabolomics is the methodology and theory to study the metabolome, including targeted approaches based on selected/multiple reaction monitoring (SRM/MRM) and untargeted approaches based on nuclear magnetic resonance (NMR) or mass spectrometry (MS). The metabolome contains all metabolites derived from sugars, lipids, proteins, and nucleic acids in a given biological system, tissue, cell, or body fluid in a metabolic network system. Metabolomic variations directly link to molecular mechanisms of a disease, reliable therapeutic targets, and effective biomarkers for prediction, diagnosis, and prognostic assessment of disease. This book presents new advances in the concept and methodology of metabolomics, as well as applications of metabolomics in the research and practice of medical and life sciences.

Mass Spectrometry-Based Metabolomics

Sastia Prama Putri,Eiichiro Fukusaki
Mass Spectrometry Based Metabolomics Book PDF

Author : Sastia Prama Putri,Eiichiro Fukusaki
Publisher : CRC Press
Page : 294 pages
File Size : 42,8 Mb
Release : 2016-04-21
Category : Science
ISBN : 9781482223774

Get Book

Mass Spectrometry-Based Metabolomics by Sastia Prama Putri,Eiichiro Fukusaki Pdf

Mass Spectrometry-Based Metabolomics: A Practical Guide is a simple, step-by-step reference for profiling metabolites in a target organism. It discusses optimization of sample preparation for urine, serum, blood, tissue, food, and plant and animal cell samples. Encompassing three different technical fields—biology, analytical chemistry, and informatics— mass spectrometry-based metabolomics can be challenging for biologists without special training in quantitative mass spectrometry. This book is designed to overcome this limitation by providing researchers with the knowledge they need to use metabolomics technology in their respective disciplines. The book summarizes all steps in metabolomics research, from experimental design to sample preparation, analytical procedures, and data analysis. Case studies are presented for easy understanding of the metabolomics workflow and its practical applications in different research fields. The book includes an in-house library and built-in software so that those new to the field can begin to analyze real data samples. In addition to being an excellent introductory text, the book also contains the latest advancements in this emerging field and can thus be a useful reference for metabolomics specialists.

Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines

Aihua Zhang,Wanying Wang
Mass Spectrometry Based Metabolomics in Clinical and Herbal Medicines Book PDF

Author : Aihua Zhang,Wanying Wang
Publisher : John Wiley & Sons
Page : 292 pages
File Size : 51,8 Mb
Release : 2021-09-07
Category : Science
ISBN : 9783527349913

Get Book

Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines by Aihua Zhang,Wanying Wang Pdf

Highlights the importance and benefit of mass spectrometry-based metabolomics for identifying biomarkers that accurately screen for potential biomarkers of diseases Mass spectrometry-based metabolomics offer new opportunities for biomarker discovery in complex diseases and may provide pathological understanding of diseases beyond traditional technologies. It is the systematic analysis of low-molecular-weight metabolites in biological samples and has been applied to discovering and identifying the perturbed pathways. Currently, mass spectrometry-based metabolomics has become an important tool in clinical research and the diagnosis of human disease. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines comprehensively presents the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics such as metabolites analysis, biomarker discovery, technical challenges, discovery of natural product, mechanism interpretation of action, discovery of active ingredients, clinical application and precision medicine, and enhancing their biomedical value in a real world of biomedicine, shedding light on the potential for spectrometry-based metabolomics. It highlights the value of mass spectrometry-based metabolomics and metabolism to address the complexity of herbal medicines in systems pharmacology, especially, to link phytochemical analysis with the assessment of pharmacological effect and therapeutic potential. Each chapter has been laid out with introduction, method, up-to-date literature, identification of biomarker, and applications Covers the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics in the discovery of biomarker, active ingredients, natural product, etc. Constitutes a unique and indispensable practical guide for any phytochemistry or related laboratory, and provides hands-on description of new techniques Provides a guide for new practitioners of pharmacologists, pharmacological scholars, drug developers, botanist, researchers of traditional medicines. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines provides a landmark of mass spectrometry-based metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all biomedical science fields.

Chinmedomics

Xijun Wang,Aihua Zhang,Hui Sun
Chinmedomics Book PDF

Author : Xijun Wang,Aihua Zhang,Hui Sun
Publisher : Academic Press
Page : 408 pages
File Size : 44,8 Mb
Release : 2015-07-15
Category : Medical
ISBN : 9780128031186

Get Book

Chinmedomics by Xijun Wang,Aihua Zhang,Hui Sun Pdf

Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine uses new experimental techniques and research to open doors in drug discovery and development related to traditional Chinese medicine (TCM). This book features a unique approach that combines chemometric analysis with metabolomics studies to illuminate significant changes that have occurred in syndrome states while simultaneously analyzing the efficacy of chemical ingredients in herbal medicines. Chapters provide cutting-edge information on traditional medicine, analytical technology, natural products, metabolomics, bioinformatics and their applications. This book provides a valuable resource for pharmacologists, pharmaceutical scientists, medicinal plant researchers, pharmacognosists and chemists working with TCM and highlights ways to further research and advances in this area in the future. Presents a practical guide for new practitioners of Chinmedomics with insights on the current use and future development of this method Each chapter includes an introduction, method, references to the latest literature, possible mechanisms of action and applications Edited by the leading experts of research related to Chinmedomics

NMR-based Metabolomics

Hector C Keun
NMR based Metabolomics Book PDF

Author : Hector C Keun
Publisher : Royal Society of Chemistry
Page : 384 pages
File Size : 51,7 Mb
Release : 2018-01-17
Category : Science
ISBN : 9781849736435

Get Book

NMR-based Metabolomics by Hector C Keun Pdf

This book describes the state of the art in the application of NMR spectroscopy to metabolomics and will be a key title for researchers and practitioners.

Methodologies for Metabolomics

Norbert W. Lutz,Jonathan V. Sweedler,Ron A. Wevers
Methodologies for Metabolomics Book PDF

Author : Norbert W. Lutz,Jonathan V. Sweedler,Ron A. Wevers
Publisher : Cambridge University Press
Page : 641 pages
File Size : 44,9 Mb
Release : 2013-01-21
Category : Medical
ISBN : 9780521765909

Get Book

Methodologies for Metabolomics by Norbert W. Lutz,Jonathan V. Sweedler,Ron A. Wevers Pdf

Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.

Serum Pharmacochemistry of Traditional Chinese Medicine

Xijun Wang,Aihua Zhang,Hui Sun
Serum Pharmacochemistry of Traditional Chinese Medicine Book PDF

Author : Xijun Wang,Aihua Zhang,Hui Sun
Publisher : Academic Press
Page : 378 pages
File Size : 52,8 Mb
Release : 2016-12-27
Category : Medical
ISBN : 9780128111482

Get Book

Serum Pharmacochemistry of Traditional Chinese Medicine by Xijun Wang,Aihua Zhang,Hui Sun Pdf

Serum Pharmacochemistry of Traditional Chinese Medicine: Technologies, Strategies and Applications provides a valuable and indispensable guide on the latest methods, research advances, and applications in this area. Chapters offer cutting-edge information on pharmacokinetics and pharmacodynamics, analytical chemistry, traditional medicine, natural products, bioinformatics, new technologies, therapeutic applications, and more. For researchers and students in academia and industry, this book provides a hands-on description of experimental techniques, along with beneficial guidelines to help advance research in the fields of Traditional Chinese Medicine and drug development. Provides a valuable guide for practitioners of serum pharmacochemistry of Traditional Chinese Medicine, along with insights to its current use and future applications Edited and written by leading scientists at the forefront of this research Presents well written chapters that include an introduction, description of the method, and identification of chemical constituents, with applications and references to the latest research and literature

Herbal Biomolecules in Healthcare Applications

Subhash C. Mandal,Amit Kumar Nayak,Amal Kumar Dhara
Herbal Biomolecules in Healthcare Applications Book PDF

Author : Subhash C. Mandal,Amit Kumar Nayak,Amal Kumar Dhara
Publisher : Academic Press
Page : 752 pages
File Size : 50,9 Mb
Release : 2021-10-05
Category : Medical
ISBN : 9780323900805

Get Book

Herbal Biomolecules in Healthcare Applications by Subhash C. Mandal,Amit Kumar Nayak,Amal Kumar Dhara Pdf

Herbal Biomolecules in Healthcare Applications presents extensive detailed information on all the vital principles, basics and fundamental aspects of multiple herbal biomolecules in the healthcare industry. This book examines important herbal biomolecules including alkaloids, glycosides, flavonoids, anthraquinones, steroids, polysaccharides, tannins and polyphenolic compounds, terpenes, fats and waxes, proteins and peptides, and vitamins. These herbal biomacromolecules are responsible for different bioactivities as well as pharmacological potentials. A systematic understanding of the extraction, purification, characterization, applications of these herbal biomolecules and their derivatives in healthcare fields is developed in this comprehensive book. Chapters explore the key topics along with an emphasis on recent research and developments in healthcare fields by leading experts. They include updated literature review of the relevant key topics, good quality illustrations, chemical structures, flow charts, well-organized tables and case studies. Herbal Biomolecules in Healthcare Applications will be useful for researchers working on natural products and biomolecules with bioactivity and nutraceutical properties. Professionals specializing in scientific areas such as biochemistry, pharmacology, analytical chemistry, organic chemistry, clinics, or engineering focused on bioactive natural products will find this book useful. Provides a study of different type of biomolecules from herbal extracts and their bioactivities as well as their application in the healthcare industry Contributions by global leaders and experts from academia, industry and regulatory agencies, who have been considered as pioneers in the application of herbal biomolecules in the diverse healthcare fields Includes updated literature review along with practical examples and research case studies

Plant Metabolomics

Kazuki Saito,Richard A. Dixon,Lothar Willmitzer
Plant Metabolomics Book PDF

Author : Kazuki Saito,Richard A. Dixon,Lothar Willmitzer
Publisher : Springer Science & Business Media
Page : 351 pages
File Size : 43,9 Mb
Release : 2006-06-29
Category : Science
ISBN : 9783540297826

Get Book

Plant Metabolomics by Kazuki Saito,Richard A. Dixon,Lothar Willmitzer Pdf

Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology. This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.

Metabolic Engineering

Sang Yup Lee,Jens Nielsen,Gregory Stephanopoulos
Metabolic Engineering Book PDF

Author : Sang Yup Lee,Jens Nielsen,Gregory Stephanopoulos
Publisher : John Wiley & Sons
Page : 1075 pages
File Size : 46,9 Mb
Release : 2021-06-02
Category : Science
ISBN : 9783527823451

Get Book

Metabolic Engineering by Sang Yup Lee,Jens Nielsen,Gregory Stephanopoulos Pdf

Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation. Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya. The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about: Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It's comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.

Mass Spectrometry in Chemical Biology

Norberto Peporine Lopes,Ricardo Roberto da Silva
Mass Spectrometry in Chemical Biology Book PDF

Author : Norberto Peporine Lopes,Ricardo Roberto da Silva
Publisher : Royal Society of Chemistry
Page : 312 pages
File Size : 49,8 Mb
Release : 2017-11-22
Category : Science
ISBN : 9781782625278

Get Book

Mass Spectrometry in Chemical Biology by Norberto Peporine Lopes,Ricardo Roberto da Silva Pdf

Mass spectrometry is one of the most widespread technologies in chemistry and has been increasingly used in biology with the rise of omics sciences. This book summarizes some important methodological approaches in mass spectrometry and applications in the field of chemical biology. The core chapters build on basic concepts introduced in the opening chapter and explore established fields such as high throughput screening, proteomics and metabolomics. Emerging applications of mass spectrometry in elucidating biosynthetic pathways, enzyme mechanisms and protein-protein interactions are then presented. Connections between these diverse research fields are highlighted throughout. The book concludes with a discussion of databases and future perspectives. This book will be a useful tool to early chemical biology researchers wishing to incorporate mass spectrometry as a tool in their research.

The Handbook of Plant Metabolomics

Wolfram Weckwerth,Guenter Kahl
The Handbook of Plant Metabolomics Book PDF

Author : Wolfram Weckwerth,Guenter Kahl
Publisher : John Wiley & Sons
Page : 422 pages
File Size : 45,9 Mb
Release : 2013-02-28
Category : Science
ISBN : 9783527669905

Get Book

The Handbook of Plant Metabolomics by Wolfram Weckwerth,Guenter Kahl Pdf

This is the newest title in the successful Molecular Plant Biology Handbook Series. Just like the other titles in the series this new book presents an excellent overview of different approaches and techniques in Metabolomics. Contributors are either from ivy-league research institutions or from companies developing new technologies in this dynamic and fast-growing field. With its approach to introduce current techniques in plant metabolomics to a wider audience and with many labs and companies considering to introduce metabolomics for their research, the title meets a growing market. The Kahl books are in addition a trusted brand for the plant science community and have always sold above expectations.

Metabolome Analysis

Silas G. Villas-Boas,Jens Nielsen,Jorn Smedsgaard,Michael A. E. Hansen,Ute Roessner-Tunali
Metabolome Analysis Book PDF

Author : Silas G. Villas-Boas,Jens Nielsen,Jorn Smedsgaard,Michael A. E. Hansen,Ute Roessner-Tunali
Publisher : John Wiley & Sons
Page : 339 pages
File Size : 47,6 Mb
Release : 2007-02-16
Category : Science
ISBN : 9780470105504

Get Book

Metabolome Analysis by Silas G. Villas-Boas,Jens Nielsen,Jorn Smedsgaard,Michael A. E. Hansen,Ute Roessner-Tunali Pdf

Providing information on the main approaches for the analysis of metabolites, this textbook: Covers basic methodologies in sample preparation and separation techniques, as well as the most recent techniques of mass spectrometry. Differentiates between primary and secondary metabolites. Includes four chapters discussing successful metabolome studies of different organisms. Highlights the analytical challenges of studying metabolites. Illustrates applications of metabolome analysis through the use of case studies.

Integration of Omics Approaches and Systems Biology for Clinical Applications

Antonia Vlahou,Fulvio Magni,Harald Mischak,Jerome Zoidakis
Integration of Omics Approaches and Systems Biology for Clinical Applications Book PDF

Author : Antonia Vlahou,Fulvio Magni,Harald Mischak,Jerome Zoidakis
Publisher : John Wiley & Sons
Page : 386 pages
File Size : 49,5 Mb
Release : 2018-02-21
Category : Science
ISBN : 9781119181149

Get Book

Integration of Omics Approaches and Systems Biology for Clinical Applications by Antonia Vlahou,Fulvio Magni,Harald Mischak,Jerome Zoidakis Pdf

Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis is put on integration of data generated from these different platforms in order to uncover the molecular landscape of diseases. The relevance of each approach to the clinical setting is explained and future applications for patient monitoring or treatment are discussed. Integration of omics Approaches and Systems Biology for Clinical Applications presents an overview of state of the art omics techniques. These methods are employed in order to obtain the comprehensive molecular profile of biological specimens. In addition, computational tools are used for organizing and integrating these multi-source data towards developing molecular models that reflect the pathophysiology of diseases. Investigation of chronic kidney disease (CKD) and bladder cancer are used as test cases. These represent multi-factorial, highly heterogeneous diseases, and are among the most significant health issues in developed countries with a rapidly aging population. The book presents novel insights on CKD and bladder cancer obtained by omics data integration as an example of the application of systems biology in the clinical setting. Describes a range of state of the art omics analytical platforms Covers all aspects of the systems biology approach—from sample preparation to data integration and bioinformatics analysis Contains specific examples of omics methods applied in the investigation of human diseases (Chronic Kidney Disease, Bladder Cancer) Integration of omics Approaches and Systems Biology for Clinical Applications will appeal to a wide spectrum of scientists including biologists, biotechnologists, biochemists, biophysicists, and bioinformaticians working on the different molecular platforms. It is also an excellent text for students interested in these fields.