Maternal Control Of Development In Vertebrates

Author : Florence Louise Marlow
Publisher : Morgan & Claypool Publishers
Page : 221 pages
File Size : 54,7 Mb
Release : 2010
Category : Family & Relationships
ISBN : 9781615040513

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Maternal Control of Development in Vertebrates by Florence Louise Marlow Pdf

Eggs of all animals contain mRNAs and proteins that are supplied to or deposited in the egg as it develops during oogenesis. These maternal gene products regulate all aspects of oocyte development, and an embryo fully relies on these maternal gene products for all aspects of its early development, including fertilization, transitions between meiotic and mitotic cell cycles, and activation of its own genome. Given the diverse processes required to produce a developmentally competent egg and embryo, it is not surprising that maternal gene products are not only essential for normal embryonic development but also for fertility. This review provides an overview of fundamental aspects of oocyte and early embryonic development and the interference and genetic approaches that have provided access to maternally regulated aspects of vertebrate development. Some of the pathways and molecules highlighted in this review, in particular, Bmps, Wnts, small GTPases, cytoskeletal components, and cell cycle regulators, are well known and are essential regulators of multiple aspects of animal development, including oogenesis, early embryogenesis, organogenesis, and reproductive fitness of the adult animal. Specific examples of developmental processes under maternal control and the essential proteins will be explored in each chapter, and where known conserved aspects or divergent roles for these maternal regulators of early vertebrate development will be discussed throughout this review. Table of Contents: Introduction / Oogenesis: From Germline Stem Cells to Germline Cysts / Oocyte Polarity and the Embryonic Axes: The Balbiani Body, an Ancient Oocyte Asymmetry / Preparing Developmentally Competent Eggs / Egg Activation / Blocking Polyspermy / Cleavage/ Mitosis: Going Multicellular / Maternal-Zygotic Transition / Reprogramming: Epigenetic Modifications and Zygotic Genome Activation / Dorsal-Ventral Axis Formation before Zygotic Genome Activation in Zebrafish and Frogs / Maternal TGF-β and the Dorsal-Ventral Embryonic Axis / Maternal Control After Zygotic Genome Activation / Compensation by Stable Maternal Proteins / Maternal Contributions to Germline Establishment or Maintenance / Perspective / Acknowledgments / References

Author : Francisco Pelegri,Michael Danilchik,Ann Sutherland
Publisher : Springer
Page : 549 pages
File Size : 42,8 Mb
Release : 2016-12-13
Category : Science
ISBN : 9783319460956

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Vertebrate Development by Francisco Pelegri,Michael Danilchik,Ann Sutherland Pdf

This book provides a comprehensive overview of topics describing the earliest steps of fertilization, from egg activation and fertilization to the activation of the zygotic genome, in various studied vertebrate model systems. The contribution of maternal and paternal factors and their role in the early embryo as parental DNA becomes modified and embryonic genes become activated is fundamental to the initiation of embryogenesis in all animal systems. It can be argued that this is a unique developmental period, when information from the parents is compressed to direct the development of the body plan of the entire organism, a process of astounding simplicity, elegance and beauty. In addition to their fundamental scientific interest, many frontiers of biomedicine, such as reproductive biology, stem cells and reprogramming, and the understanding of intergenerational diseases, depend on advances in our knowledge of these early processes. Vertebrate Development: Maternal to Zygotic Control brings together chapters from experts in various disciplines describing the latest advances related to this important developmental transition. Each chapter is a synthesis of knowledge relevant to all vertebrates, with details on specific systems as well as comparisons between the various studied vertebrate models. The editorial expertise encompasses the fields of major vertebrate model systems (mammalian, amphibian and teleost) ensuring a balanced approach to various topics. This unique book—with its combination of in-depth and up-to-date basic research, inter-species comprehensiveness and emphasis on the very early stages of animal development—is essential for research scientists studying vertebrate development, as well as being a valuable resource for college educators teaching advanced courses in developmental biology.

Author : National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology
Publisher : National Academies Press
Page : 348 pages
File Size : 47,5 Mb
Release : 2000-12-21
Category : Nature
ISBN : 9780309070867

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Scientific Frontiers in Developmental Toxicology and Risk Assessment by National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology Pdf

Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

Author : Anonim
Publisher : Academic Press
Page : 0 pages
File Size : 40,5 Mb
Release : 2015-09-14
Category : Science
ISBN : 0124095232

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The Maternal-to-Zygotic Transition by Anonim Pdf

The Maternal-to-Zygotic Transition provides users with an expert accounting of the mechanisms and functions of this transition in a range of animal and plant models. The book provides critical information on how maternal gene products program the initial development of all animal and plant embryos, then undergoing a series of events, termed the maternal-to-zygotic transition, during which maternal products are cleared and zygotic genome activation takes over the developmental control.

Author : Florence L. Marlow
Publisher : Biota Publishing
Page : 222 pages
File Size : 48,6 Mb
Release : 2010-12-01
Category : Science
ISBN : 9781615040520

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Maternal Control of Development in Vertebrates by Florence L. Marlow Pdf

Eggs of all animals contain mRNAs and proteins that are supplied to or deposited in the egg as it develops during oogenesis. These maternal gene products regulate all aspects of oocyte development, and an embryo fully relies on these maternal gene products for all aspects of its early development, including fertilization, transitions between meiotic and mitotic cell cycles, and activation of its own genome. Given the diverse processes required to produce a developmentally competent egg and embryo, it is not surprising that maternal gene products are not only essential for normal embryonic development but also for fertility. This review provides an overview of fundamental aspects of oocyte and early embryonic development and the interference and genetic approaches that have provided access to maternally regulated aspects of vertebrate development. Some of the pathways and molecules highlighted in this review, in particular, Bmps, Wnts, small GTPases, cytoskeletal components, and cell cycle regulators, are well known and are essential regulators of multiple aspects of animal development, including oogenesis, early embryogenesis, organogenesis, and reproductive fitness of the adult animal. Specific examples of developmental processes under maternal control and the essential proteins will be explored in each chapter, and where known conserved aspects or divergent roles for these maternal regulators of early vertebrate development will be discussed throughout this review.

Author : Werner A. Mueller,Monika Hassel,Maura Grealy
Publisher : Springer
Page : 725 pages
File Size : 51,8 Mb
Release : 2015-01-03
Category : Science
ISBN : 9783662437841

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Development and Reproduction in Humans and Animal Model Species by Werner A. Mueller,Monika Hassel,Maura Grealy Pdf

This book describes human development including sexual reproduction and stem cell research with the development of model organisms that are accessible to genetic and experimental analysis in readily understandable texts and 315 multi-colored graphics. The introductory account of model organisms selected from the entire animal kingdom presents general principles, which are then outlined in subsequent chapters devoted to, for example, sexual development; genes controlling development and their contemporary molecular-analysis methods; production of clones and transgenic animals; development of the nervous and circulatory systems; regenerative medicine and ageing. Finally the evolution of developmental toolkits and novelties is discussed including the genetic basis of the enlargement of the human forebrain. Separate boxes are devoted to controversial questions such as the benefits and problems of prenatal diagnostics or the construction of ancient body plans.

Author : Patrick J. Babin,Joan Cerdà,Esther Lubzens
Publisher : Springer Science & Business Media
Page : 513 pages
File Size : 45,5 Mb
Release : 2007-08-20
Category : Nature
ISBN : 9781402062339

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The Fish Oocyte by Patrick J. Babin,Joan Cerdà,Esther Lubzens Pdf

This book addresses the growing needs in deciphering the biological processes associated with fish reproduction, in view of the growth of aquaculture and the dwindling natural stocks of commercially important fish. It presents a comprehensive overview on egg production in fish, from the standpoint of the oocyte. With this view in mind, the book includes chapters on oocyte development (oogenesis), hormonal regulation and hormone receptors, formation of the egg envelopes, growth, accumulation of nutrients and maternal transcripts, maturation, hydration, ovulation and fertilization. A special emphasis is placed on using state-of-the-art tools including electron microscopy for discerning the ultra-structure of the follicle and genomic/proteomic tools to fully understand biological basis of fish reproduction. Studies on promoting oocyte maturation, ovulation and spawning in farmed fish and preservation of fish oocytes at low temperatures are also included. The book will appeal to University lecturers, students, research scientists and those associated with culture of fish in freshwater or marine aquaculture.

Author : Peter D. Gluckman,Alan Beedle,Tatjana Buklijas,Felicia Low,Mark A. Hanson
Publisher : Oxford University Press
Page : 401 pages
File Size : 55,9 Mb
Release : 2016
Category : Science
ISBN : 9780199663927

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Principles of Evolutionary Medicine by Peter D. Gluckman,Alan Beedle,Tatjana Buklijas,Felicia Low,Mark A. Hanson Pdf

This is the first integrated and comprehensive textbook to explain the principles of evolutionary biology from a medical perspective and to focus on how medicine and public health might utilise evolutionary biology.

Author : Nelson R. Cabej
Publisher : Newnes
Page : 308 pages
File Size : 51,5 Mb
Release : 2013-04-01
Category : Science
ISBN : 9780124017290

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Building the Most Complex Structure on Earth by Nelson R. Cabej Pdf

Building the Most Complex Structure on Earth provides readers with a basic biological education an easy and understandable introduction into a new epigenetic theory of development and evolution. This is a novel theory that describes the epigenetic mechanisms of the development and evolution of animals and explains the colossal evolution and diversification of animals from a new post-genetic perspective. Modern biology has demonstrated the existence of a common genetic toolkit in the animal kingdom, but neither the number of genes nor the evolution of new genes is responsible for the development and evolution of animals. The failure to understand how the same genetic toolkit is used to produce millions of widely different animal forms remains a perplexing conundrum in modern biology. The novel theory shows that the development and evolution of the animal kingdom are functions of epigenetic mechanisms, which are the competent users of the genetic toolkit. Provides a comprehensive view of the epigenetic aspects of reproduction, development, and evolution. Highly rigorous, but simple enough for readers with only a basic knowledge of biology.

Author : Leon W. Browder
Publisher : Springer Science & Business Media
Page : 637 pages
File Size : 43,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461568148

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Oogenesis by Leon W. Browder Pdf

This book launches a new continuing series in developmental biology. Any new publishing venture in science can only be justified if it satisfies a need and fulfills that need in an exemplary way. I believe that there is an acute need for comprehensive treatises on specialized topics in developmental biology-especially because this is a very diverse field that receives con tributions from a wide variety of disciplines. It is difficult to remain abreast of progress in multifaceted topics and to understand how the various aspects of a topic interrelate. The volumes that will comprise this series are designed to facilitate those processes. Each volume of this series will attempt to convey the current status of research and thought on a specific topic in development, place current research within historical perspective, and lay the intellectual groundwork for future research. These volumes are intended to provide an in-depth background on these topics for advanced undergraduates, graduate stu dents, and senior scientists. An investigator considering research in one of these areas will get an overview of the field as well as discover the status of recent research in the area.

Author : Charles J. Epstein,Robert P. Erickson,Anthony Joseph Wynshaw-Boris
Publisher : Oxford University Press, USA
Page : 1110 pages
File Size : 47,5 Mb
Release : 2004
Category : Medical
ISBN : 9780195145021

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Inborn Errors of Development by Charles J. Epstein,Robert P. Erickson,Anthony Joseph Wynshaw-Boris Pdf

In this book, the clinical chapters are organized into sections by defined developmental pathways or gene families, and each section is preceded by a general overview. For each disorder the authors cover the disease-causing genes, the role of these genes in development as elucidated in model organisms, the human mutations that have been identified, and the developmental pathogenesis of the condition. Clinical descriptions, along with discussions of therapy and counseling, are provided. This book will be an invaluable resource for physicians, dentists, and other health professionals and for basic scientists interested in developmental processes and genetic perturbations that affect them.

Author : Patrick P. L. Tam,W. James Nelson,Janet Rossant
Publisher : Unknown
Page : 0 pages
File Size : 51,6 Mb
Release : 2013
Category : Science
ISBN : 1936113244

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Mammalian Development by Patrick P. L. Tam,W. James Nelson,Janet Rossant Pdf

"A subject collection from Cold Spring Harbor perspectives in biology."

Author : Alessandro Minelli
Publisher : Cambridge University Press
Page : 205 pages
File Size : 55,6 Mb
Release : 2021-05-20
Category : Science
ISBN : 9781108836777

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Understanding Development by Alessandro Minelli Pdf

Using familiar examples and clear arguments, this volume offers fresh alternatives to widespread misconceptions about biological development.

Author : Benedikt Hallgrimsson Ph.D.,Brian K. Hall Ph.D.
Publisher : Univ of California Press
Page : 472 pages
File Size : 53,7 Mb
Release : 2011-04-11
Category : Science
ISBN : 9780520948822

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Epigenetics by Benedikt Hallgrimsson Ph.D.,Brian K. Hall Ph.D. Pdf

Illuminating the processes and patterns that link genotype to phenotype, epigenetics seeks to explain features, characters, and developmental mechanisms that can only be understood in terms of interactions that arise above the level of the gene. With chapters written by leading authorities, this volume offers a broad integrative survey of epigenetics. Approaching this complex subject from a variety of perspectives, it presents a broad, historically grounded view that demonstrates the utility of this approach for understanding complex biological systems in development, disease, and evolution. Chapters cover such topics as morphogenesis and organ formation, conceptual foundations, and cell differentiation, and together demonstrate that the integration of epigenetics into mainstream developmental biology is essential for answering fundamental questions about how phenotypic traits are produced.

Author : William Barry Wood
Publisher : Unknown
Page : 694 pages
File Size : 50,6 Mb
Release : 1988
Category : Science
ISBN : UOM:39015049386132

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The Nematode Caenorhabditis Elegans by William Barry Wood Pdf