Medical Implications Of Biofilms

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Medical Implications of Biofilms

Michael Wilson,Deirdre Devine

Author : Michael Wilson,Deirdre Devine
Publisher : Cambridge University Press
Page : 340 pages
File Size : 48,9 Mb
Release : 2003-09-01
Category : Science
ISBN : 1139438018

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Medical Implications of Biofilms by Michael Wilson,Deirdre Devine Pdf

Human tissues often support large, complex microbial communities growing as biofilms that can cause a variety of infections. As a result of an increased use of implanted medical devices, the incidence of these biofilm-associated diseases is increasing: the non-shedding surfaces of these devices provide ideal substrata for colonisation by biofilm-forming microbes. The consequences of this mode of growth are far-reaching. As microbes in biofilms exhibit increased tolerance towards antimicrobial agents and decreased susceptibility to host defence systems, biofilm-associated diseases are becoming increasingly difficult to treat. Not surprisingly, therefore, interest in biofilms has increased dramatically. The application of microscopic and molecular techniques has revolutionised our understanding of biofilm structure, composition, organisation, and activities, resulting in important advances in the prevention and treatment of biofilm-related diseases. The purpose of this book, which was first published in 2003, is to bring these advances to the attention of clinicians and medical researchers.

Medical Implications of Biofilms

Michael Wilson,Deirdre Devine

Author : Michael Wilson,Deirdre Devine
Publisher : Unknown
Page : 314 pages
File Size : 50,7 Mb
Release : 2003
Category : Biofilms
ISBN : 0511203527

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Medical Implications of Biofilms by Michael Wilson,Deirdre Devine Pdf

As biofilms exhibit increased tolerance towards anti-microbial agents and decreased susceptibility to host defense systems, biofilm-associated diseases have become difficult to treat. New techniques have revolutionized our understanding of biofilms, resulting in advances in the prevention and treatment of biofilm-related diseases. This book presents these advances to clinicians and medical researchers.

Biofilms and Implantable Medical Devices

Ying Deng,Wei Lv

Author : Ying Deng,Wei Lv
Publisher : Woodhead Publishing
Page : 238 pages
File Size : 53,6 Mb
Release : 2016-10-24
Category : Technology & Engineering
ISBN : 9780081003985

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Biofilms and Implantable Medical Devices by Ying Deng,Wei Lv Pdf

Biofilms and Implantable Medical Devices: Infection and Control explores the increasing use of permanent and semi-permanent implants and indwelling medical devices. As an understanding of the growth and impact of biofilm formation on these medical devices and biomaterials is vital for protecting the health of the human host, this book provides readers with a comprehensive treatise on biofilms and their relationship with medical devices, also reporting on infections and associated strategies for prevention. Provides useful information on the fundamentals of biofilm problems in medical devices Discusses biofilm problems in a range of medical devices Focuses on strategies for prevention of biofilm formation

Medical Biofilms

Jana Jass,Susanne Surman,James Walker

Author : Jana Jass,Susanne Surman,James Walker
Publisher : John Wiley & Sons
Page : 328 pages
File Size : 40,7 Mb
Release : 2003-04-02
Category : Science
ISBN : 0471988677

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Medical Biofilms by Jana Jass,Susanne Surman,James Walker Pdf

Biofilms are formed by microorganisms growing on surfaces and comprise a series of microcolonies interspersed with spaces through which fluids and other microorganisms move. In medicine, the primary problems are biofilms associated with implants: infections are increasingly difficult to treat with traditional antibiotics and removal of the implant often becomes essential, frequently leading to higher morbidity and mortality. This will be the first book dedicated to medical biofilms. It will cover much recent information on the problems of biofilms, how to detect them and how to control their presence.

The Rise of Virulence and Antibiotic Resistance in Staphylococcus aureus

Shymaa Enany,Laura Crotty Alexander

Author : Shymaa Enany,Laura Crotty Alexander
Publisher : BoD – Books on Demand
Page : 226 pages
File Size : 41,5 Mb
Release : 2017-03-08
Category : Medical
ISBN : 9789535129837

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The Rise of Virulence and Antibiotic Resistance in Staphylococcus aureus by Shymaa Enany,Laura Crotty Alexander Pdf

Staphylococcus aureus S. aureus is a growing issue both within hospitals and community because of its virulence determinants and the continuing emergence of new strains resistant to antimicrobiotics. In this book, we present the state of the art of S. aureus virulence mechanisms and antibiotic-resistance profiles, providing an unprecedented and comprehensive collection of up-to-date research about the evolution, dissemination, and mechanisms of different staphylococcal antimicrobial resistance patterns alongside bacterial virulence determinants and their impact in the medical field. We include several review chapters to allow readers to better understand the mechanisms of methicillin resistance, glycopeptide resistance, and horizontal gene transfer and the effects of alterations in S. aureus membranes and cell walls on drug resistance. In addition, we include chapters dedicated to unveiling S. aureus pathogenicity with the most current research available on S. aureus exfoliative toxins, enterotoxins, surface proteins, biofilm, and defensive responses of S. aureus to antibiotic treatment.

Biofilm-Mediated Diseases: Causes and Controls

Rina Rani Ray,Moupriya Nag,Dibyajit Lahiri

Author : Rina Rani Ray,Moupriya Nag,Dibyajit Lahiri
Publisher : Springer Nature
Page : 284 pages
File Size : 41,9 Mb
Release : 2021-05-05
Category : Medical
ISBN : 9789811607455

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Biofilm-Mediated Diseases: Causes and Controls by Rina Rani Ray,Moupriya Nag,Dibyajit Lahiri Pdf

This book reviews the current concepts in biofilm formation and its implications in human health and disease. The initial chapters introduce the mechanisms of biofilm formation and its composition. Subsequently, the chapters discuss the role of biofilm in acute and chronic infections. It also explores the pivotal role of both innate and adaptive immunity on the course of biofilm infection. In addition, the book elucidates the bacterial biofilm formation on implantable devices and the current approaches to its treatment and prevention. It analyzes the possible relationship between antimicrobial resistance and biofilm formation. Finally, the book also summarizes the current state-of-the-art therapeutic approaches for preventing and treating biofilms. This book is a useful resource for researchers in the field of microbiology, clinical microbiology, and also medical practitioners.

The Role of Biofilms in Device-Related Infections

Mark Shirtliff,Jeff G. Leid

Author : Mark Shirtliff,Jeff G. Leid
Publisher : Springer Science & Business Media
Page : 276 pages
File Size : 42,9 Mb
Release : 2008-12-19
Category : Medical
ISBN : 9783540681199

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The Role of Biofilms in Device-Related Infections by Mark Shirtliff,Jeff G. Leid Pdf

Approximately 60% of all hospital-associated infections, over one million cases per year, are due to biofilms that have formed on indwelling medical devices. Device-related biofilm infections increase hospital stays and add over one billion dollars/year to U.S. hospitalization costs. Since the use and the types of indwelling medical devices commonly used in modern healthcare are continuously expanding, especially with an aging population, the incidence of biofilm infections will also continue to rise. The central problem with microbial biofilm infections of foreign bodies is their propensity to resist clearance by the host immune system and all antimicrobial agents tested to date. In fact, compared to their free floating, planktonic counterparts, microbes within a biofilm are 50 – 500 times more resistant to antimicrobial agents. Therefore, achieving therapeutic and non-lethal dosing regimens within the human host is impossible. The end result is a conversion from an acute infection to one that is persistent, chronic, and recurrent, most often requiring device removal in order to eliminate the infection. This text will describe the major types of device-related infections, and will explain the host, pathogen, and the unique properties of their interactions in order to gain a better understanding of these recalcitrant infections.

Microbial Biofilms in Healthcare

Karen Vickery

Author : Karen Vickery
Publisher : MDPI
Page : 166 pages
File Size : 53,8 Mb
Release : 2020-03-16
Category : Medical
ISBN : 9783039284108

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Microbial Biofilms in Healthcare by Karen Vickery Pdf

Biofilms are ubiquitous and their presence in industry can lead to production losses. However, nowhere do biofilms impact human health and welfare as much as those that are found contaminating the healthcare environment, surgical instruments, equipment, and medical implantable devices. Approximately 70% of healthcare-associated infections are due to biofilm formation, resulting in increased patient morbidity and mortality. Biofilms formed on medical implants are recalcitrant to antibiotic treatment, which leaves implant removal as the principal treatment option. In this book, we investigate the role of biofilms in breast and dental implant disease and cancer. We include in vitro models for investigating treatment of chronic wounds and disinfectant action against Candida sp. Also included are papers on the most recent strategies for treating biofilm infection ranging from antibiotics incorporated into bone void fillers to antimicrobial peptides and quorum sensing.

Biofilms in Human Diseases: Treatment and Control

Sunil Kumar,Niharika Chandra,Leena Singh,Muhammad Zaffar Hashmi,Ajit Varma

Author : Sunil Kumar,Niharika Chandra,Leena Singh,Muhammad Zaffar Hashmi,Ajit Varma
Publisher : Springer Nature
Page : 318 pages
File Size : 42,9 Mb
Release : 2019-11-19
Category : Medical
ISBN : 9783030307578

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Biofilms in Human Diseases: Treatment and Control by Sunil Kumar,Niharika Chandra,Leena Singh,Muhammad Zaffar Hashmi,Ajit Varma Pdf

This book highlights treatment strategies for bacterial biofilms in connection with a variety of human diseases. In particular, it reviews bacterial biofilm formation and its mechanism. Topics covered include biofilms in human health, the role of biofilms in mediating human diseases, and methods for testing bacterial biofilms. Further sections concentrate on biofilm-mediated diseases in different parts of the human gastrointestinal tract, while therapeutic strategies for biofilm control and natural agents that disrupt bacterial biofilms are also covered. Readers will also find the latest advances in probiotics and biofilms, as well as the use of probiotics to counteract biofilm-associated infections. Biofilms and antimicrobial resistance are discussed. Subsequent chapters address the management of inflammatory bowel disease via probiotics biofilms, as well as the role of probiotics bacteria in the treatment of human diseases associated with bacterial biofilms. The book is chiefly intended for clinicians/scientists in the fields of medical microbiology, applied microbiology, biochemistry, and biotechnology.

Microbial Biofilms

Dharumadurai Dhanasekaran,Nooruddin Thajuddin

Author : Dharumadurai Dhanasekaran,Nooruddin Thajuddin
Publisher : BoD – Books on Demand
Page : 526 pages
File Size : 55,5 Mb
Release : 2016-07-13
Category : Medical
ISBN : 9789535124351

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Microbial Biofilms by Dharumadurai Dhanasekaran,Nooruddin Thajuddin Pdf

In the book Microbial Biofilms: Importance and applications, eminent scientists provide an up-to-date review of the present and future trends on biofilm-related research. This book is divided with four subdivisions as biofilm fundamentals, applications, health aspects, and their control. Moreover, this book also provides a comprehensive account on microbial interactions in biofilms, pyocyanin, and extracellular DNA in facilitating Pseudomonas aeruginosa biofilm formation, atomic force microscopic studies of biofilms, and biofilms in beverage industry. The book comprises a total of 21 chapters from valued contributions from world leading experts in Australia, Bulgaria, Canada, China, Serbia, Germany, Italy, Japan, the United Kingdom, the Kingdom of Saudi Arabia, Republic of Korea, Mexico, Poland, Portugal, and Turkey. This book may be used as a text or reference for everyone interested in biofilms and their applications. It is also highly recommended for environmental microbiologists, soil scientists, medical microbiologists, bioremediation experts, and microbiologists working in biocorrosion, biofouling, biodegradation, water microbiology, quorum sensing, and many other related areas. Scientists in academia, research laboratories, and industry will also find it of interest.

Bacterial Biofilms

Tony Romeo

Author : Tony Romeo
Publisher : Springer Science & Business Media
Page : 294 pages
File Size : 54,5 Mb
Release : 2008-02-26
Category : Medical
ISBN : 9783540754183

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Bacterial Biofilms by Tony Romeo Pdf

Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.

Biofilms in Medicine, Industry and Environmental Biotechnology

Piet Lens,V. O'Flaherty,A. P. Moran,P. Stoodley,T. Mahony

Author : Piet Lens,V. O'Flaherty,A. P. Moran,P. Stoodley,T. Mahony
Publisher : IWA Publishing
Page : 634 pages
File Size : 55,7 Mb
Release : 2003-04-30
Category : Science
ISBN : 9781843390190

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Biofilms in Medicine, Industry and Environmental Biotechnology by Piet Lens,V. O'Flaherty,A. P. Moran,P. Stoodley,T. Mahony Pdf

Biofilms are of great practical importance for beneficial technologies such as water and wastewater treatment and bioremediation of groundwater and soil. In other settings biofilms cause severe problems, for example in 65% of bacterial infections currently treated by clinicians (particularly those associated with prosthetics and implants), accelerated corrosion in industrial systems, oil souring and biofouling. Until recently, the structure and function of biofilms could only be inferred from gross measures of biomass and metabolic activity. This limitation meant that investigators involved in biofilm research and application had only a crude understanding of the microbial ecology, physical structure and chemical characteristics of biofilms. Consequently, opportunities for the exploitation and control of biofilms were very limited. The past decade has witnessed the development of several new techniques to elucidate the structure and function of biofilms. Examples include: the use of molecular probes that identify different microbes in complex communities as well as their metabolic functions; the use of microsensors that show concentration gradients of key nutrients and chemicals; the use of confocal laser scanning microscopy to describe the physical structure of biofilms and the development of a new generation of mathematical models that allow for the prediction of biofilm structure and function. However, much progress remains to be made in efforts to understand, control and exploit biofilms. This timely book will introduce its readers to the structure and function of biofilms at a fundamental level as determined during the past decade of research, including: Extracellular polymers as the biofilm matrix; Biofilm phenotype (differential gene expression, interspecies signalling); Biofilm ecology; Biofilm monitoring; Resistance of biofilms to antimicrobial agents and Biofilm abatement. Biofilms in Medicine, Industry and Environmental Technology offers a holistic and multi-disciplinary description of the topic, including biofilm formation and composition, but also biofilm monitoring, disinfection and control. All these aspects are presented from three points of views: medical, industrial and environmental biotechnological in a compact, easy to read format.

Microbial Biofilms

Chaminda Jayampath Seneviratne

Author : Chaminda Jayampath Seneviratne
Publisher : CRC Press
Page : 334 pages
File Size : 49,5 Mb
Release : 2017-07-12
Category : Medical
ISBN : 9781351646420

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Microbial Biofilms by Chaminda Jayampath Seneviratne Pdf

Microbial Biofilms: Omics Biology, Antimicrobials and Clinical Implications is a comprehensive survey of microbial biofilms and their role in human health and disease with contributions from world renowned experts in molecular microbiology, proteomics, genomics, metabolomics and infectious diseases. The book is intended to serve as a guide for students, as well as a reference for researchers, clinicians and industry professionals. The chapters cover bacterial and fungal microbiomes, and the latest omics techniques organized in a clear and up-to-date manner. One of the highlights of this book is the comprehensive information on "omics of microbial biofilms". The chapters dedicated to metagenomics, proteomics and metabolomics are designed to provide a simple and holistic review of the current knowledge and, the applications of these techniques in the field of microbial biofilms. In addition to introductory chapters on microbial biofilms and their clinical implications, subsequent chapters delve into oral biofilms, their composition, and metagenomic diversity. Thereafter, mechanisms of drug resistance in microbial biofilms are reviewed, as well as the proteomic and metabolomic characterization of this resistance. The book includes a comprehensive discussion of persister cells and host–microbial interactions on mucosal surfaces. Finally, the book concludes with a summary of novel therapeutic approaches for biofilms such as synbiotics and biogenics.

Oral Biofilms

S. Eick

Author : S. Eick
Publisher : Karger Medical and Scientific Publishers
Page : 247 pages
File Size : 47,8 Mb
Release : 2020-12-21
Category : Medical
ISBN : 9783318068528

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Oral Biofilms by S. Eick Pdf

Biofilms are highly organized polymicrobial communities that are embedded in an extracellular matrix and formed on natural and artificial surfaces. In the oral cavity, biofilms are formed not only on natural teeth, but also on restorative materials, prosthetic constructions, and dental implants. Oral diseases like caries, gingivitis, periodontitis, and also pulp inflammation are associated with biofilms. This publication is an up-to-date overview on oral biofilms from different clinically relevant perspectives. Experts comprising basic researchers and clinicians report on recent research relating to biofilms - from general summaries to recommendations for daily clinical work. This book covers all aspects of oral biofilms, including models used in the laboratory, biofilms in dental water unit lines, periodontal and peri-implant biofilms, caries-related biofilms, halitosis, endodontic biofilms, and Candida infections, as well as biofilms on dental materials and on orthodontic appliances. Several chapters deal with anti-biofilm therapy, from the efficacy of mechanical methods and the use of antimicrobials, to alternative concepts. This publication is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on biofilms.

Biofilms in Infection Prevention and Control

Steven L. Percival,David Williams,Tracey Cooper,Jacqueline Randle

Author : Steven L. Percival,David Williams,Tracey Cooper,Jacqueline Randle
Publisher : Academic Press
Page : 394 pages
File Size : 42,7 Mb
Release : 2014-01-30
Category : Science
ISBN : 9780123977519

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Biofilms in Infection Prevention and Control by Steven L. Percival,David Williams,Tracey Cooper,Jacqueline Randle Pdf

Biofilms in Infection and Disease Control: A Healthcare Handbook outlines the scientific evidence and rationale for the prevention of infection, the role biofilms play in infection control, and the issues concerning their resistance to antimicrobials. This book provides practical guidance for healthcare and infection control professionals, as well as students, for preventing and controlling infection. Biofilms are the most common mode of bacterial growth in nature. Highly resistant to antibiotics and antimicrobials, biofilms are the source of more than 65 percent of health care associated infections (HCAI), which, according to the WHO, affect 1.4 million people annually. Biofilms are involved in 80 percent of all microbial infections in the body, including those associated with medical devices such as catheters, endotracheal tubes, joint prostheses, and heart valves. Biofilms are also the principle causes of infections of the middle-ear, dental caries, gingivitis, prostatitis and cystic fibrosis. Importantly, biofilms also significantly delay wound healing and reduce antimicrobial efficiency in at-risk or infected skin wounds. Provides specific procedures for controlling and preventing infection Includes case studies of HCAI, and identifies appropriate treatments Presents national government standards for infection prevention and control Includes extensive references and links to websites for further information

Medical Implications Of Biofilms

Medical Implications of Biofilms by Michael Wilson,Deirdre Devine Pdf

Medical Implications of Biofilms by Michael Wilson,Deirdre Devine Pdf

Biofilms and Implantable Medical Devices by Ying Deng,Wei Lv Pdf

Medical Biofilms by Jana Jass,Susanne Surman,James Walker Pdf

The Rise of Virulence and Antibiotic Resistance in Staphylococcus aureus by Shymaa Enany,Laura Crotty Alexander Pdf

Biofilm-Mediated Diseases: Causes and Controls by Rina Rani Ray,Moupriya Nag,Dibyajit Lahiri Pdf

The Role of Biofilms in Device-Related Infections by Mark Shirtliff,Jeff G. Leid Pdf

Microbial Biofilms in Healthcare by Karen Vickery Pdf

Biofilms in Human Diseases: Treatment and Control by Sunil Kumar,Niharika Chandra,Leena Singh,Muhammad Zaffar Hashmi,Ajit Varma Pdf

Microbial Biofilms by Dharumadurai Dhanasekaran,Nooruddin Thajuddin Pdf

Bacterial Biofilms by Tony Romeo Pdf

Biofilms in Medicine, Industry and Environmental Biotechnology by Piet Lens,V. O'Flaherty,A. P. Moran,P. Stoodley,T. Mahony Pdf

Microbial Biofilms by Chaminda Jayampath Seneviratne Pdf

Oral Biofilms by S. Eick Pdf

Biofilms in Infection Prevention and Control by Steven L. Percival,David Williams,Tracey Cooper,Jacqueline Randle Pdf

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