Microwave Fixation Of Labile Metabolites

Author : C. Leroy Blank,William B. Stavinoha,Yuji Maruyama
Publisher : Elsevier
Page : 204 pages
File Size : 43,9 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9781483159058

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Microwave Fixation of Labile Metabolites by C. Leroy Blank,William B. Stavinoha,Yuji Maruyama Pdf

Microwave Fixation of Labile Metabolites documents the proceedings of an official Satellite Symposium of the 8th International Congress of Pharmacology held in Tokyo, Japan, on 25 July 1981. The Symposium was entitled ""Drug Effects on Rapidly Metabolized Compounds in the CNS: Rapid Tissue Fixation with Microwave Irradiation."" The volume begins with a discussion of the use of microwave irradiation to study the concentration and interrelationships of neurochemicals in the brain. This is followed by papers on the effects of immobilization on the increases in cerebellar cyclic GMP induced by cold exposure or apomorphine; importance of rapid enzymatic inactivation prior to the determination of endogenous levels of catecholamines; use of glycolic acid to study catecholamines in the brain following microwave irradiation. Also include are studies on methods for preventing the post mortem increase in ?-aminobutyric acid (GABA); the effect of microwave irradiation on catecholamine levels in the central nervous system; and effect of microwave irradiation in the brain histamine level of rats.

Author : Toshiharu Nagatsu,Abraham Fisher,Mitsuo Yoshida
Publisher : Springer Science & Business Media
Page : 797 pages
File Size : 52,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468458442

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Basic, Clinical, and Therapeutic Aspects of Alzheimer’s and Parkinson’s Diseases by Toshiharu Nagatsu,Abraham Fisher,Mitsuo Yoshida Pdf

This two-volume work contains the full text of the oral and poster presentations and the general discussion at the round table discussion of the Second International Conference on Alzheimer's and Parkinson's Diseases: Basic and Therapeutic Strategies, held at the Kyoto Park Hotel in Kyoto, Japan, on November 6-10, 1989. The First Conference was held at the Aviya Sonesta Hotel in Eilat, Israel, on March 24-27, 1985. The record of this First Conference was published by Plenum Press in 1986 as Volume 29 in Advances in Behavioral Biology, under the title "Alzheimer's and Parkinson's Diseases: Strategies for Research and Development." We are happy that the comprehensive texts of the oral and poster presentations of the Second Conference could again be published within the framework of this series. Since the First Conference in 1985, rapid progress has been made in both basic and 'therapeutic aspects of these diseases. About 700 scientists from allover the world participated in the Second Conference, and 300 papers were presented in oral and poster sessions. Many people and organizations have helped to organize this multi disciplinary international conference and hence have contributed to the scientific quality of these two volumes. We thank the members of the organizing committee, the organizations that provided financial support, and the contributing scientists for their enthusiastic participation. These two volumes follow the same publishing philosophy as the volume derived from the First Conference. They span a broad spectrum of topics and bridge preclinical and clinical concepts related to these diseases.

Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1968 pages
File Size : 53,6 Mb
Release : 2024-07-01
Category : Medicine
ISBN : UOM:39015074107544

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Current Catalog by National Library of Medicine (U.S.) Pdf

First multi-year cumulation covers six years: 1965-70.

Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1972 pages
File Size : 48,6 Mb
Release : 1984
Category : Medicine
ISBN : MINN:31951M01375430O

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National Library of Medicine Current Catalog by National Library of Medicine (U.S.) Pdf

Author : Claude Nicolau
Publisher : Elsevier
Page : 207 pages
File Size : 52,6 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9781483160443

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Oxygen Transport in Red Blood Cells by Claude Nicolau Pdf

Oxygen Transport in Red Blood Cells contains the proceedings of the 12th Aharon Katzir Katchalsky Conference held at Tours, France on April 4-7, 1984. Organized into 16 chapters, this book begins with a discussion on the influence of heme pocket geometry on ligand binding to heme proteins. Subsequent chapters describe a genetic approach to producing oxygen affinity differences; clinical importance of the oxygen transport function of preserved red blood cells; methods for the measurement of oxygen equilibrium curves of red cell suspensions and hemoglobin solutions; and aspects of oxygen supply to tissue. Other chapters elucidate interactions between hemoglobin and erythrocyte membrane and membrane protein oxidation; incorporation of allosteric effectors of hemoglobin in red blood cells; and significance of low hemoglobin oxygen affinity.The interaction of ligands and other molecules with hemoglobin and the storage of red blood cells having incorporated exogenous allosteric effectors of hemoglobin are also explained.

Author : Hansjurgen Matthies
Publisher : Elsevier
Page : 429 pages
File Size : 48,6 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483161310

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Learning and Memory by Hansjurgen Matthies Pdf

Learning and Memory: Mechanisms of Information Storage in the Nervous System contains the proceedings of the Seventh International Neurobiological Symposium held at Magdeburg on October 28 to November 2, 1985. Organized into four sections, this book first elucidates the synaptic long-term potentiation. Section II explores hippocampal functions, and Section III describes the biochemistry of memory formation. The last section addresses the principles and modification of learning behavior.

Author : S. H. Parvez
Publisher : Elsevier Publishing Company
Page : 446 pages
File Size : 42,9 Mb
Release : 1993
Category : Medical
ISBN : UOM:39015029103234

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Methods in Neurotransmitter and Neuropeptide Research by S. H. Parvez Pdf

Hardbound. This two-part book provides the most advanced biochemical and histochemical analytical methods on neurotransmitters, neuromodulators, and neuropeptides described by international specialists. The biochemical methods include liquid chromatography/electrochemistry, liquid chromatography/fluorescence and chemiluminescence detection, gas chromatography or liquid chromatography with mass spectrometry, and immunoassays.Morphological and physiological methods are also described, including immunohistochemistry, in situ hybridization, in vivo microdialysis, electrophysiological analysis, microwave irradiation, electrophysiological analysis, micro-anatomical dissection, peptide sequence analysis, quantitative autoradiographic analysis, and isolated CNS preparations. The neurotransmitters and neuropeptides include catecholamines, indoleamines, histamine, polyamines, and various neuropeptides, and their related enzymes. The book is the most comprehensiv

Author : Donard Dwyer
Publisher : Academic Press
Page : 555 pages
File Size : 51,5 Mb
Release : 2002
Category : Medical
ISBN : 0123668522

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Glucose Metabolism in the Brain by Donard Dwyer Pdf

Regulation of glucose at the biochemical level affects every area of the brain, and has impact from cellular to behavioral brain function. It plays an important role in diseases such as diabetes, stroke, schizophrenia and drug abuse as well as in normal and dysfunctional memory and cognition. This volume represents a thorough examination of all the major issues that are relevant to glucose metabolism by brain cells in relation to disease, combining basic research and clinical findings in a single, indispensable reference. Key Features * Serves as an essential reference on glucose metabolism in the brain * Presents authoritative accounts by leading researchers in the field * Includes thorough reviews with provocative sections on future directions

Author : Anonim
Publisher : Elsevier
Page : 555 pages
File Size : 41,7 Mb
Release : 2002-11-04
Category : Medical
ISBN : 9780080491592

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Glucose Metabolism in the Brain by Anonim Pdf

Regulation of glucose at the biochemical level affects every area of the brain, and has impact from cellular to behavioral brain function. It plays an important role in diseases such as diabetes, stroke, schizophrenia and drug abuse as well as in normal and dysfunctional memory and cognition. This volume represents a thorough examination of all the major issues that are relevant to glucose metabolism by brain cells in relation to disease, combining basic research and clinical findings in a single, indispensable reference. Serves as an essential reference on glucose metabolism in the brain Presents authoritative accounts by leading researchers in the field Includes thorough reviews with provocative sections on future directions

Author : Janet V. Passonneau
Publisher : Unknown
Page : 440 pages
File Size : 46,6 Mb
Release : 1980
Category : Brain
ISBN : UOM:39015000256910

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Cerebral Metabolism and Neural Function by Janet V. Passonneau Pdf

Author : Mauro DiNuzzo,Arne Schousboe
Publisher : Springer Nature
Page : 443 pages
File Size : 44,7 Mb
Release : 2019-10-31
Category : Medical
ISBN : 9783030274801

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Brain Glycogen Metabolism by Mauro DiNuzzo,Arne Schousboe Pdf

This book aims to provide a state-of-the-art summary of what is currently known about brain glycogen metabolism, detailing the recent advances in our understanding of why glycogen is so critical for normal brain function. The role of glycogen in cellular neurophysiology remains largely unclear and its specific contribution to the energy demand of brain cells is still elusive.Glycogen is the sole cerebral glucose reserve and is emerging as a fundamental component of brain energy metabolism. Pharmacological or genetic manipulation of glycogen metabolism in the brain impairs memory formation and increases susceptibility to epileptic seizures and cortical spreading depression. Glycogen is also directly implicated in abnormal neuronal excitability and mental retardation that characterize brain disorders like Lafora disease and Pompe disease.

Author : Anonim
Publisher : Unknown
Page : 450 pages
File Size : 46,7 Mb
Release : 1999
Category : Animal experimentation
ISBN : MINN:31951D01699945S

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Using Animals in Intramural Research by Anonim Pdf

Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 542 pages
File Size : 50,5 Mb
Release : 1975
Category : Medicine
ISBN : UOM:39015074115604

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Literature Search by National Library of Medicine (U.S.) Pdf

Author : D.W. McCandles
Publisher : Springer Science & Business Media
Page : 459 pages
File Size : 46,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468412093

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Cerebral Energy Metabolism and Metabolic Encephalopathy by D.W. McCandles Pdf

In recent years, there has been rapid growth in knowledge pertaining to the nervous system. This has, in some measure, been due to the development and application of a number of techniques such as the 2-deoxyglucose method and microchemical methods for measuring metabolites and regional cerebral blood flow. Data from the application of these techniques are just beginning to be collected, and the next few years promise to bring many new and exciting findings. The study of energy metabolism in brain is particularly interesting due to the fact that although the brain has scant energy reserves (as compared with the liver), it has one of the highest metabolic rates in the body. Recent studies from several laboratories have shown a surprising divergence of re sponses to metabolic insult in different areas of brain. In this regard, the cer ebellum, for example, may have metabolic features which are uniqve from those of any other region. The high-energy phosphate compounds ATP and phos phocreatine, supplied by the oxidative metabolism of glucose, are necessary for normal cerebral functions such as the maintenance of membrane potentials, transmission of impulses, and synthetic processes. Interruption of substrate or "poisoning" of the system by a variety of means lead to a rapid change in cellular energetics, and ultimately cell death. From the clinical standpoint, an interesting feature of metabolic encephalopathy is that in many cases, early diagnosis and treatment may result in a rapid reversal of symptoms.

Author : Josef Kuře
Publisher : BoD – Books on Demand
Page : 266 pages
File Size : 53,7 Mb
Release : 2011-09-15
Category : Medical
ISBN : 9789533072609

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Euthanasia by Josef Kuře Pdf

No one really wants to die, or do they? From classical times to our post-modern era of medical high tech, societies have struggled with the thorny issue of euthanasia, and what it entails. Who shall be entitled to a "good death" and in what form shall it arrive? This book provides the reader with insight and enlightenment on the medical, philosophical, social, cultural and existential aspects of "good death" amid our digitized, individualized and ageing society, hampered by rising health care costs but unchained from one standardized level of care.