Mitochondrial Dysfunction A Functional Medicine Approach To Aging And Diseases

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Mitochondrial Dysfunction: A Functional Medicine Approach to Aging and Diseases

John Binnington
Mitochondrial Dysfunction A Functional Medicine Approach to Aging and Diseases Book PDF

Author : John Binnington
Publisher : Foster Academics
Page : 0 pages
File Size : 46,7 Mb
Release : 2023-09-26
Category : Medical
ISBN : 1646465598

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Mitochondrial Dysfunction: A Functional Medicine Approach to Aging and Diseases by John Binnington Pdf

Mitochondria are double-membrane-bound organelles found in eukaryotic cells. They build cable-like structures and deliver energy to cells with the help of oxidative phosphorylation (OXPHOS) process. Aging causes a wide range of interrelated conditions and is also a leading cause of various human diseases. The age-associated changes in mitochondria are linked with deterioration in mitochondrial function. The accumulation of oxidative damage and mutations caused by reactive oxygen species (ROS), mitochondrial functionality, and DNA volume and integrity decline with age. Mitochondrial dysfunction includes an increase in oxidative damage and a reduction in oxidative capacity, and plays a significant role in biological aging. The accumulation of dysfunctional mitochondria occurs in all the tissues with aging, including brain, liver and skeletal muscle. These dysfunctional mitochondria are marked and removed through an autophagic process named mitophagy. Mitochondrial dysfunction occurs in many neurodegenerative diseases such as Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), Friedreich's ataxia (FRDA) and Alzheimer's disease (AD). This book explores all the important aspects of mitochondrial dysfunction and its impact on aging and diseases. Experts and students actively engaged in researches on mitochondrial dysfunction will find it full of crucial and unexplored concepts.

Mitochondrial Dysfunction: A Functional Medicine Approach to Diagnosis and Treatment: Get Rid of Fat, Fatigue, and Brain Fog

Michael T. Chang
Mitochondrial Dysfunction A Functional Medicine Approach to Diagnosis and Treatment Get Rid of Fat Fatigue and Brain Fog Book PDF

Author : Michael T. Chang
Publisher : Unknown
Page : 194 pages
File Size : 47,6 Mb
Release : 2019-09-08
Category : Health & Fitness
ISBN : 1733397310

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Mitochondrial Dysfunction: A Functional Medicine Approach to Diagnosis and Treatment: Get Rid of Fat, Fatigue, and Brain Fog by Michael T. Chang Pdf

Are of sick and tired of being tired, overweight, brain fogged and depressed? You have tried everything and nothing makes a difference. The answer may lie deep inside your cells called the mitochondria, the energy factories that power the cell. By rebooting them in a proven treatment method, you can not only get rid of your symptoms but also prevent chronic degenerative diseases like cancer and Alzheimer's and even slow the aging process. Functional medicine can help you diagnose and treat mitochondrial dysfunction.Dr. Michael Chang, MD, CFMP, Board certified in Pathology and Laboratory Medicine, draws from his experience at Healed and Whole Clinic using a validated treatment approach to this condition. He has also personally experienced mitochondrial fatigue stemming from biomechanical leg pain from which he has now recovered by applying the same treatments as outlined in this book.

Mitochondrial Dysfunction in Aging and Diseases of Aging

Richard H. Haas
Mitochondrial Dysfunction in Aging and Diseases of Aging Book PDF

Author : Richard H. Haas
Publisher : MDPI
Page : 268 pages
File Size : 46,9 Mb
Release : 2019-10-01
Category : Science
ISBN : 9783039213276

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Mitochondrial Dysfunction in Aging and Diseases of Aging by Richard H. Haas Pdf

This collection of review articles authored by international experts pulls together current information about the role of mitochondria in aging and diseases of aging. Mitochondria are vitally important cellular organelles and undergo their own aging process becoming less efficient in aged animals including humans. These changes have wide-ranging significance contributing to immune dysfunction (autoimmunity and immune deficiency), inflammation, delayed healing, skin and retinal damage, cancer and most of the degenerative diseases of aging. Mitochondrial aging predisposes to drug toxicity in the geriatric population and to many of the features of normal aging. The research detailed in this book summarizes current understanding of the role of mitochondria in the complex molecular changes of aging, moving on to specific diseases of aging. Mitochondrial dysfunction is an important target for development of treatments for aging and disease. The last article details how exercise is a treatment and combats many features of the aging process.

Mitochondrial Dysfunction

Lawrence H. Lash,Dean P. Jones
Mitochondrial Dysfunction Book PDF

Author : Lawrence H. Lash,Dean P. Jones
Publisher : Elsevier
Page : 528 pages
File Size : 52,9 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483218618

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Mitochondrial Dysfunction by Lawrence H. Lash,Dean P. Jones Pdf

Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

Mitochondria and the Future of Medicine

Lee Know
Mitochondria and the Future of Medicine Book PDF

Author : Lee Know
Publisher : Chelsea Green Publishing
Page : 274 pages
File Size : 55,9 Mb
Release : 2018
Category : MEDICAL
ISBN : 9781603587679

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Mitochondria and the Future of Medicine by Lee Know Pdf

With information for patients and practitioners on optimizing mitochondrial function for greater health and longevity Why do we age? Why does cancer develop? What's the connection between heart failure and Alzheimer's disease, or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the Exercise Paradox? Why do antioxidant supplements sometimes do more harm than good? Many will be amazed to learn that all these questions, and many more, can be answered by a single point of discussion: mitochondria and bioenergetics. In Mitochondria and the Future of Medicine, Naturopathic Doctor Lee Know tells the epic story of mitochondria, the widely misunderstood and often-overlooked powerhouses of our cells. The legendary saga began over two billion years ago, when one bacterium entered another without being digested, which would evolve to create the first mitochondrion. Since then, for life to exist beyond single-celled bacteria, it's the mitochondria that have been responsible for this life-giving energy. By understanding how our mitochondria work, in fact, it is possible to add years to our lives, and life to our years. Current research, however, has revealed a dark side: many seemingly disconnected degenerative diseases have tangled roots in dysfunctional mitochondria. However, modern research has also endowed us with the knowledge on how to optimize its function, which is of critical importance to our health and longevity. Lee Know offers cutting-edge information on supplementation and lifestyle changes for mitochondrial optimization, such as CoQ10, D-Ribose, cannabinoids, and ketogenic dietary therapy, and how to implement their use successfully. Mitochondria and the Future of Medicine is an invaluable resource for practitioners interested in mitochondrial medicine and the true roots of chronic illness and disease, as well as anyone interested in optimizing their health.

Mitochondrial Dysfunction in Ageing and Diseases

Jaime M. Ross,Giuseppe Coppotelli,Lars Olson
Mitochondrial Dysfunction in Ageing and Diseases Book PDF

Author : Jaime M. Ross,Giuseppe Coppotelli,Lars Olson
Publisher : MDPI
Page : 543 pages
File Size : 41,8 Mb
Release : 2018-09-28
Category : Electronic book
ISBN : 9783038422518

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Mitochondrial Dysfunction in Ageing and Diseases by Jaime M. Ross,Giuseppe Coppotelli,Lars Olson Pdf

This book is a printed edition of the Special Issue "Mitochondrial Dysfunction in Ageing and Diseases" that was published in IJMS

Mitochondria Dysfunction

Tailor Fran
Mitochondria Dysfunction Book PDF

Author : Tailor Fran
Publisher : Independently Published
Page : 0 pages
File Size : 42,6 Mb
Release : 2024-02-12
Category : Self-Help
ISBN : 9798879422375

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Mitochondria Dysfunction by Tailor Fran Pdf

Attention: We all age, and with it comes a decline in health. But have you ever considered the tiny powerhouses lurking inside your cells, playing a pivotal role in this process? 'Mitochondria dysfunction: The unexpected roles of Mitochondria in Aging and Diseases' delves into the fascinating and often surprising world of these cellular power plants, revealing their profound impact on your health and longevity. Interest: Imagine mitochondria as tiny factories fueled by oxygen and nutrients, generating the energy that keeps your body ticking. But what happens when these factories malfunction? This book unveils the unexpected ways in which mitochondrial dysfunction contributes to not just aging, but also a spectrum of diseases, from neurodegenerative disorders like Alzheimer's and Parkinson's to chronic conditions like heart disease and diabetes. Desire: This isn't just a scientific exploration; it's a guide to understanding your own health. You'll discover the latest research on how lifestyle choices, diet, and even exercise can influence mitochondrial function, potentially slowing down the aging process and reducing your risk of disease. The book empowers you to become an active participant in your own well-being, offering evidence-based strategies for optimizing your cellular powerhouses. Action: Forget fad diets and quick fixes. This book equips you with the knowledge to make informed decisions about your health. You'll learn about cutting-edge research in areas like mitochondrial-targeted therapies, offering a glimpse into the future of personalized medicine focused on rejuvenating your cellular powerhouses. 'More than just understanding aging and disease, this book empowers you to take control of your health and unlock the potential for a longer, healthier life.'

Mitochondrial Dysfunction and Nanotherapeutics

Marcos Roberto de Oliveira
Mitochondrial Dysfunction and Nanotherapeutics Book PDF

Author : Marcos Roberto de Oliveira
Publisher : Academic Press
Page : 602 pages
File Size : 55,6 Mb
Release : 2021-07-15
Category : Science
ISBN : 9780323886185

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Mitochondrial Dysfunction and Nanotherapeutics by Marcos Roberto de Oliveira Pdf

Mitochondrial Dysfunction and Nanotherapeutics: Aging, Diseases, and Nanotechnology-Related Strategies in Mitochondrial Medicine provides a comprehensive overview of mitochondrial dysfunction and current strategies for targeting the organelle. Based on the most current research, the editor lined up a team of worldwide experts to cover the most exciting research in the area, considering the impact through the human life span. This book is structured in two parts that provide a good balance of foundational and applied content. Part I deals with an overview of mitochondrial dysfunction and its role in the aging process, including metabolic diseases, neuro-affective and neurodegenerative disorders, sepsis, and toxicological aspects. Part II covers therapeutic substance delivery to mitochondria with a focus on cancer, neurodegenerative diseases, and increasing the bioavailability of natural compounds of interest. Several nanoscale strategies are described. Mitochondrial Dysfunction and Nanotherapeutics: Aging, Diseases, and Nanotechnology-Related Strategies in Mitochondrial Medicine is a complete resource for researchers in this exciting field. Its comprehensive coverage makes this book particularly interesting to bioscience researchers looking to understand the foundations of mitochondrial health throughout the human life span. Additionally, clinician researchers, medical doctors, nutritionists, pharmacologists, and sports scientists may be attracted to the detailed information on the organelle-targeted delivery strategies. Contains detailed information on mitochondrial dysfunction Reviews our current understanding of the role of mitochondria in aging Includes coverage of specific conditions, including sports and affective disorders, among others Discusses mitochondria targeted delivery of therapeutic compounds

Mitochondrial Dysfunction in Aging and Diseases of Aging

Richard H. Haas
Mitochondrial Dysfunction in Aging and Diseases of Aging Book PDF

Author : Richard H. Haas
Publisher : Unknown
Page : 1 pages
File Size : 46,8 Mb
Release : 2019
Category : Electronic books
ISBN : 3039213288

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Mitochondrial Dysfunction in Aging and Diseases of Aging by Richard H. Haas Pdf

This collection of review articles authored by international experts pulls together current information about the role of mitochondria in aging and diseases of aging. Mitochondria are vitally important cellular organelles and undergo their own aging process becoming less efficient in aged animals including humans. These changes have wide-ranging significance contributing to immune dysfunction (autoimmunity and immune deficiency), inflammation, delayed healing, skin and retinal damage, cancer and most of the degenerative diseases of aging. Mitochondrial aging predisposes to drug toxicity in the geriatric population and to many of the features of normal aging. The research detailed in this book summarizes current understanding of the role of mitochondria in the complex molecular changes of aging, moving on to specific diseases of aging. Mitochondrial dysfunction is an important target for development of treatments for aging and disease. The last article details how exercise is a treatment and combats many features of the aging process.

Clinical Autonomic and Mitochondrial Disorders

Nicholas L. DePace,Joseph Colombo
Clinical Autonomic and Mitochondrial Disorders Book PDF

Author : Nicholas L. DePace,Joseph Colombo
Publisher : Springer
Page : 614 pages
File Size : 45,8 Mb
Release : 2019-08-01
Category : Medical
ISBN : 9783030170165

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Clinical Autonomic and Mitochondrial Disorders by Nicholas L. DePace,Joseph Colombo Pdf

This book establishes and specifies a rigorously scientific and clinically valid basis for nonpharmaceutical approaches to many common diseases and disorders found in clinical settings. It includes lifestyle and supplement recommendations for beginning and maintaining autonomic nervous system and mitochondrial health and wellness. The book is organized around a six-pronged mind-body wellness program and contains a series of clinical applications and frequently asked questions. The physiologic need and clinical benefit and synergism of all six aspects working together are detailed, including the underlying biochemistry, with exhaustive references to statistically significant and clinically relevant studies. The book covers a range of clinical disorders, including anxiety, arrhythmia, atherosclerosis, bipolar disease, dementia, depression, fatigue, fibromyalgia, heart diseases, hypertension, mast cell disorder, migraine, and PTSD. Clinical Autonomic and Mitochondrial Disorders: Diagnosis, Prevention, and Treatment for Mind-Body Wellness is an essential resource for physicians, residents, fellows, medical students, and researchers in cardiology, primary care, neurology, endocrinology, psychiatry, and integrative and functional medicine. It provides therapy options to the indications and diagnoses published in the authors' book Clinical Autonomic Dysfunction (Springer, 2014).

Mitochondria in Health and Disease

Ray Griffiths
Mitochondria in Health and Disease Book PDF

Author : Ray Griffiths
Publisher : Singing Dragon
Page : 338 pages
File Size : 45,6 Mb
Release : 2018-04-19
Category : Health & Fitness
ISBN : 9780857012883

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Mitochondria in Health and Disease by Ray Griffiths Pdf

What are the functions of mitochondria in the human body? Why might they stop working properly and what can happen as a result? How can personalized nutrition help to optimize mitochondrial function and prevent or address chronic conditions? This innovative book explores the incredibly complex biochemical roles of mitochondria in health and disease. When healthy, mitochondria provide us with ninety percent of our body's energy. When unhealthy, this can lead to many chronic and degenerative conditions including cancer and Alzheimer's disease. This guide helps practitioners to identify the mitochondrial dysfunction underlying a wide range of health complaints, and provides inspiration about relevant and emerging mitochondria-supportive dietary regimes and nutrients to explore within the model of personalized nutrition.

Mitochondria Diet

Jeffrey Winzant
Mitochondria Diet Book PDF

Author : Jeffrey Winzant
Publisher : No Fluff Publishing
Page : 47 pages
File Size : 52,7 Mb
Release : 2023-01-26
Category : Health & Fitness
ISBN : PKEY:6610000435234

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Mitochondria Diet by Jeffrey Winzant Pdf

Did you know that mitochondrial health is an essential key to longevity and overall well-being? Mitochondria are often overlooked in the body’s complex cellular structure. They may not get as much attention as the brain or heart, but they are integral to overall health just like any other organ, and your health can be affected by the inner workings of these tiny organelles. For example, when your cells don’t use energy properly from food because they cannot metabolize glucose (a type of sugar), your mitochondria cellular structures stop functioning efficiently, resulting in insulin resistance as well—both upstream triggers for health problems like cardiovascular disease, diabetes, cancer, Alzheimer’s Disease, Parkinson’s Disease and much more. Fortunately, there are many steps that you can take to manage these mitochondrial dysfunctions through nutrition. That’s why we have outlined a 3-week meal plan designed with your mitochondria in mind. First things first, it’s a good idea to understand what mitochondria are and why they are vital for optimal health. Stay tuned for a deep dive into what they do, why you should care about them, and how you can take better care of them through nutrition. In this guide, you’ll discover: ● What are mitochondria ● Diet tips to help improve your mitochondria function ● Symptoms you can tell your cellular structures are not working properly ● A seven-day weekly plan ● Sample recipes to follow

The Disease Delusion

Dr. Jeffrey S. Bland
The Disease Delusion Book PDF

Author : Dr. Jeffrey S. Bland
Publisher : Harper Collins
Page : 434 pages
File Size : 55,9 Mb
Release : 2014-05-06
Category : Health & Fitness
ISBN : 9780062290755

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The Disease Delusion by Dr. Jeffrey S. Bland Pdf

For decades, Dr. Jeffrey Bland has been on the cutting edge of Functional Medicine, which seeks to pinpoint and prevent the cause of illness, rather than treat its symptoms. Managing chronic diseases accounts for three quarters of our total healthcare costs, because we’re masking these illnesses with pills and temporary treatments, rather than addressing their underlying causes, he argues. Worse, only treating symptoms leads us down the path of further illness. In The Disease Delusion, Dr. Bland explains what Functional Medicine is and what it can do for you. While advances in modern science have nearly doubled our lifespans in only four generations, our quality of life has not reached its full potential. Outlining the reasons why we suffer chronic diseases from asthma and diabetes to obesity, arthritis and cancer to a host of other ailments, Dr. Bland offers achievable, science-based solutions that can alleviate these common conditions and offers a roadmap for a lifetime of wellness.

Clinical Mitochondrial Medicine

Patrick F. Chinnery,Michael J. Keogh
Clinical Mitochondrial Medicine Book PDF

Author : Patrick F. Chinnery,Michael J. Keogh
Publisher : Cambridge University Press
Page : 229 pages
File Size : 40,7 Mb
Release : 2018-05-17
Category : Medical
ISBN : 9780521132985

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Clinical Mitochondrial Medicine by Patrick F. Chinnery,Michael J. Keogh Pdf

This interactive clinical textbook takes a system- and case-based approach in understanding mitochondrial disorders in clinical practice.

The Human Mitochondrial Genome

Giuseppe Gasparre,Anna Maria Porcelli
The Human Mitochondrial Genome Book PDF

Author : Giuseppe Gasparre,Anna Maria Porcelli
Publisher : Academic Press
Page : 596 pages
File Size : 47,9 Mb
Release : 2020-07-23
Category : Science
ISBN : 9780128226421

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The Human Mitochondrial Genome by Giuseppe Gasparre,Anna Maria Porcelli Pdf

The Human Mitochondrial Genome: From Basic Biology to Disease offers a comprehensive, up-to-date examination of human mitochondrial genomics, connecting basic research to translational medicine across a range of disease types. Here, international experts discuss the essential biology of human mitochondrial DNA (mtDNA), including its maintenance, repair, segregation, and heredity. Furthermore, mtDNA evolution and exploitation, mutations, methods, and models for functional studies of mtDNA are dealt with. Disease discussion is accompanied by approaches for treatment strategies, with disease areas discussed including cancer, neurodegenerative, age-related, mtDNA depletion, deletion, and point mutation diseases. Nucleosides supplementation, mitoTALENs, and mitoZNF nucleases are among the therapeutic approaches examined in-depth. With increasing funding for mtDNA studies, many clinicians and clinician scientists are turning their attention to mtDNA disease association. This book provides the tools and background knowledge required to perform new, impactful research in this exciting space, from distinguishing a haplogroup-defining variant or disease-related mutation to exploring emerging therapeutic pathways. Fully examines recent advances and technological innovations in the field, enabling new mtDNA studies, variant and mutation identification, pathogenic assessment, and therapies Disease discussion accompanied by diagnostic and therapeutic strategies currently implemented clinically Outlines and discusses essential research protocols and perspectives for young scientists to pick up Features an international team of authoritative contributors from basic biologists to clinician-scientists